Busch Lab

ZMP

mmp11a

Ensembl ID:
ENSDARG00000026325
ZFIN ID:
ZDB-GENE-070817-3
Human Orthologue:
MMP11
Human Description:
matrix metallopeptidase 11 (stromelysin 3) [Source:HGNC Symbol;Acc:7157]
Mouse Orthologue:
Mmp11
Mouse Description:
matrix metallopeptidase 11 Gene [Source:MGI Symbol;Acc:MGI:97008]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa41243 Nonsense Mutation detected in F1 DNA Not yet available
sa8388 Nonsense Mutation detected in F1 DNA Not yet available
sa41244 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa16310 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa41243
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077280 Nonsense 97 483 2 8
Genomic Location (Zv9):
Chromosome 8 (position 31658785)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30801511
GRCz11 8 30810743
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTCCAGGGCCACTGGTCCTAAACGTTGTGGCGTGCCAGACTATCCCGAA[C/T]AGAGAGATGTGCATCTCCGCCAGAAACGATATGTGCTCTTTGGAGGACGC
Long Flanking Sequence:
TAAAAATATCCTATGTGTCTGACTTCTTCTGGTGTTTTACTGGCAGTTAGCAAAAAATGACTTAAAGGTGAATATTCCACCACCTGCTGGATTAGAAGTATGGACCGCAACTGAAAGGATGCTGGTTTAGCATATGTTGTACCAGGTTAAGTTGAATTACCAACTTTGTTGTTTTAACTTACAAAATTATGTTGAAAAAACTAAAATGCAGAATAATTTTTAGTGTATAGTGATCTACCATCAGGAGCTAGCCAGCTAACCATTATCACAAACTTTTATTGTTACCATCAGGCTAATGTAGCTTTTCCATGTTTCCACTGCAGGGTTTGTCATATATTCCTCATTTGCACTCTGAGAAGAGGAGAGGCAGAGTCCCTCACCCACAGGACACCTTCAAACCTCCAGCATGGCCGAAAGAAGAGCCACATATCAACACACCACTCAGGAACAGCTCCAGGGCCACTGGTCCTAAACGTTGTGGCGTGCCAGACTATCCCGAA[C/T]AGAGAGATGTGCATCTCCGCCAGAAACGATATGTGCTCTTTGGAGGACGCTGGCCAAAAACTGACCTCACCTACAAGTAAGGTGTAAAAAAATTAGAAACAATTATTAGTCATTTATGATGTTGTTACAGTTATATCAGGGAAAAACTTAAGCTTGCATCGGTTGAGTGTAGGAAAAAGATAATAATAGAGAGGCACAAGAAGAACATCCACACCATAAAAACTAAAATGACATGTATAGACAACAGCGGACAACAATCTGAGGAAACCACAGGCTATAAAGACTAACATACATGCAGAACCAAACAAGACACAGGTGACACTAATAATAAACCATGGAAACAGATAAGTGTCTCAAAATAAGAGTCTCAAAACCAAACTAGATGCAACACATTTAAGATATTATACGTATTGGCATGAGGAATCCTTTAGAAAGTGTATGTTTAAAAACATTATGAACGTTATGTTAATATAATATTATGTCACATACTAAGAGAAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8388
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077280 Nonsense 114 483 2 8
Genomic Location (Zv9):
Chromosome 8 (position 31658838)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30801564
GRCz11 8 30810796
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGATGTGCATCTCCGCCAGAAACGATATGTGCTCTTTGGAGGACGCTG[G/A]CCAAAAACTGACCTCACCTACAAGTAAGGTGTAMAAAAATTAGAAACAAT
Long Flanking Sequence:
AAAATGACTTAAAGGTGAATATTCCACCACCTGCTGGATTAGAAGTATGGACCGCAACTGAAAGGATGCTGGTTTAGCATATGTTGTACCAGGTTAAGTTGAATTACCAACTTTGTTGTTTTAACTTACAAAATTATGTTGAAAAAACTAAAATGCAGAATAATTTTTAGTGTATAGTGATCTACCATCAGGAGCTAGCCAGCTAACCATTATCACAAACTTTTATTGTTACCATCAGGCTAATGTAGCTTTTCCATGTTTCCACTGCAGGGTTTGTCATATATTCCTCATTTGCACTCTGAGAAGAGGAGAGGCAGAGTCCCTCACCCACAGGACACCTTCAAACCTCCAGCATGGCCGAAAGAAGAGCCACATATCAACACACCACTCAGGAACAGCTCCAGGGCCACTGGTCCTAAACGTTGTGGCGTGCCAGACTATCCCGAACAGAGAGATGTGCATCTCCGCCAGAAACGATATGTGCTCTTTGGAGGACGCTG[G/A]CCAAAAACTGACCTCACCTACAAGTAAGGTGTAAAAAAATTAGAAACAATTATTAGTCATTTATGATGTTGTTACAGTTATATCAGGGAAAAACTTAAGCTTGCATCGGTTGAGTGTAGGAAAAAGATAATAATAGAGAGGCACAAGAAGAACATCCACACCATAAAAACTAAAATGACATGTATAGACAACAGCGGACAACAATCTGAGGAAACCACAGGCTATAAAGACTAACATACATGCAGAACCAAACAAGACACAGGTGACACTAATAATAAACCATGGAAACAGATAAGTGTCTCAAAATAAGAGTCTCAAAACCAAACTAGATGCAACACATTTAAGATATTATACGTATTGGCATGAGGAATCCTTTAGAAAGTGTATGTTTAAAAACATTATGAACGTTATGTTAATATAATATTATGTCACATACTAAGAGAAAAAAAAACACTGGTTGGTTGTAATTGAGATCATTTATTTTAAGTTGTTTTTGAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41244
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077280 Essential Splice Site 356 483 6 8
Genomic Location (Zv9):
Chromosome 8 (position 31668336)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30811062
GRCz11 8 30820294
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATAGACGCCGCCTATGAAGACAAAAAGGGCAATATCTGGTTCTTTGAAG[G/A]TGGGTGAGTGCAGCGGCACTGGCTGACTCTGGTGATTTGCGGTTGGAGGA
Long Flanking Sequence:
ATTGTGCTGGTATGCCAACAACAGAATTAAAAACTGGTTTTGCAATACTTTCAAGCTGAATCTCCATGAACTGTGTGTTCACATTAAACACAAAACATTTGAACACCTTCAGCAAACTCATCCCAACATGACAGGTGGCTTTAACCTCATCCACTACACAATATACAACAGTAAATTGAGATAAATTATTTCAAATACTCGGATATAACCAAAAGACTGTTTATCTGAACAAGCTGATGCGTTCCCTTCATTCTCCCTTTGTTTATTCAGTCTCCTCTTTTCTCACTGTTTGCAGCCTGACGCTTGTCACACAGATTTCGATGCTGTGTCTATAATCCGTGGGGAATTGTTCTTCTTCAAGGCCAGCTATGCGTGGCGCATCAGGGATGGCCGTCTGCAGGCCGGATACCCTGCGCTGGCCTCCCGACACTGGAGTGGCATTCCACAGAAAATAGACGCCGCCTATGAAGACAAAAAGGGCAATATCTGGTTCTTTGAAG[G/A]TGGGTGAGTGCAGCGGCACTGGCTGACTCTGGTGATTTGCGGTTGGAGGACAGGATTAGACAAGCCTGGTTATATACAAATGTATGGTGACGGGTGGTGCGGTACTTCCCCTTGACCCATATCTGAAGCGTCCCACTTTGTGAAGGGCATGACTGAACACAACCACGCTGAACACTCACTGCTAACAACTGACAAACACACACGCATGTTGTGCAGGACAGTTCCTAAACAGTTTTGTACTCTTATGGGTGGTTGCTGCAGTTTAAATAGTTTATAAGTTAATTAAATTTTCTAAATTAGAAGCATTAAAGATTGAAAATGTGGGTTGGAAAATGTAGTTTGGTCATGTTGAATCTAATAGCATCGATTCGATCTGAGTCAAATAGCTACTGTGTATGAGTTCAAATATGCTGTAAATGTACTTCATTTTTTACCCACTAGAGGACACTAGACAGACAGTTTTATGGAAATGTCAATATGTCACATAGCACTATTAAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16310
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000077280 Nonsense 405 483 7 8
Genomic Location (Zv9):
Chromosome 8 (position 31670654)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 30813380
GRCz11 8 30822612
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGCTRCGTGTAAAGGAGCACCACAGCCAGCACACATACTTCTTCAAGTCT[G/T]GAAACTACTGGCGTTTGGATCCTCAAGAGAACCGAGTGGAMWCGTCTGCC
Long Flanking Sequence:
AAGCACGCATGCACGTGGGAACGGTGGGCGGGGAAAAGCAGCTCATTTGCATTTAAAGCTACAGGCTTCAAAAACAGCTACACTGTACTCAGACACCAAAACGGGCAGATTCTGGAGGTTATAATAAATACGCAGATTCTGGAGACACCAGAGGTATATCTTACATCTTGTAAAAGGAGTAAAATAGGTGCCCTTTAAAGTTAGACACGTTAGCACCAACCTGTTGGAACCACAGGAACAAGAAAATGCATAAGCAAGACTTTTCAAGCATATGATGCGAAATTGAAATAGTTACATTGAGTAAAATCATACATGAAAGCAGTGATATGTCTAATGAATCTTTCCCTTATGTCTTAGGTTCCAACTACTGGGTGTTTGATGCCGAGCACAGGATTAAAGGACCAGACTCTCTACTATCTTTAGGCCTCCGTGTCTCAAACATTCAGGCCGCGCTGCGTGTAAAGGAGCACCACAGCCAGCACACATACTTCTTCAAGTCT[G/T]GAAACTACTGGCGTTTGGATCCTCAAGAGAACCGAGTGGACACGTCTGCCCCCCGGCGGATCCAGCAAGACTGGTGGGGTGTTCCTGAGGAGATTGATGCTGCCTTCCAGGAGGCCAGCGGTATGTCCAGACCAGCCTTTTACAGATGTATTAGTAGTGAAAGTGAAGATTACTATGAAAGAAATCAGGTTGTGAGTTAAAACTAGTTTGCTGAATCTGTGCTTTGAATGAAGTTAGTAAGTCACTTAATCAGGCATTTTCAACCACACATTTAATTGATATATTATATCATTATTTTTGTTTTAATTATTTAATTTCATATTGGCTTCACGAGGCAGAGTGGGAGGTTAGTGCTTGTGTTAAACACAAAGGAAGATATATTGAAGAAAAAAAGCAGCCATTGGCAGTATTTTTTGTTCCAACTGCAGCTGCATTTCCCAACATTTTTCACAATATCTTGTTTTGTGTAAAAGTTTTGAACCATCTGAGAAAGTAAATGG
Associated Phenotype:
Not determined