Busch Lab

ZMP

mbd1

Ensembl ID:
ENSDARG00000025699
ZFIN ID:
ZDB-GENE-030131-6318
Description:
methyl-CpG binding domain protein 1 [Source:RefSeq peptide;Acc:NP_001038218]
Human Orthologue:
MBD1
Human Description:
methyl-CpG binding domain protein 1 [Source:HGNC Symbol;Acc:6916]
Mouse Orthologue:
Mbd1
Mouse Description:
methyl-CpG binding domain protein 1 Gene [Source:MGI Symbol;Acc:MGI:1333811]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa7223 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa21916 Nonsense Available for shipment Available now
sa35091 Nonsense Available for shipment Available now
sa21917 Essential Splice Site Available for shipment Available now
sa41843 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa21918 Nonsense Available for shipment Available now
sa31833 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa7223
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033914 None None 964 None 16
ENSDART00000035629 None None 850 None 15
ENSDART00000124131 Essential Splice Site None 961 None 17
ENSDART00000147179 Essential Splice Site None 66 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26493724)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25322549
GRCz11 11 25560165
KASP Assay ID:
554-4754.1 (used for ordering genotyping assays)
KASP Sequence:
GTCAGTTATTTAAAATTTACCAATGTGTGGCTCGTTAAGGKGTTWACAGG[T/G]AGGKTTTTAAAAATGTCGCCGTCGTATTWATGACTTTTCATGTAACCGAA
Long Flanking Sequence:
ACATTTAAAAGAGTTCATGGATTATACAAAACAGGAAAAGAATAACTGAATAATATTAGAAATAGGTGGCTTAACCTAGTGATATGAATGATAAAAAGAACATTACATGTTATAAAGGATAATTATAAATAATAGAGATTAATAATACATTAATATAGAAAATATAAATACATTAGACATTTTCTTAACGTTACACCAATTTCCTTTGATTTGTTAGAAATGTCCTCGGTAAAAGCCAAAAACAACAACTCAATAACAGTATACAAAAAATATAATAAATATGCATAATCTTCATATGGGATGAAACAGAAAAGAAGACCATTTAATCAGATCATTTAATAAGAAGACACAAAATGAATCAGCTTTGTGTGCCACGAGACGTGAGCTTTAATTATTCGGAACGAGTCACGGGTTTCCGGGTTACAGCAGCACTTCCGGCTTCTCTTCAGTGTCAGTTATTTAAAATTTACCAATGTGTGGCTCGTTAAGGTGTTAACAGG[T/G]AGGTTTTTAAAAATGTCGCCGTCGTATTAATGACTTTTCATGTAACCGAATCACAAAACTCCGCAAATAGTGCAAGAAAACCTCACTATACAGTGTCTTTTGCAATAATTTCACGCTTGCTAGCACATTAGCCACCATGCTAACTATTTGCGCTGATACTTGCTCGGCTGTGTCTCAAAACCTAGCGTGTTGGCTACCTAGAACGCACCAAGAGTCGGGGTTTAGTAAACAAAACATTTGTTTTTTTCTTCCGTAAAGCAACAATAGGCCTTTGAATGCAGATGCGGGTGCCTGTATCGAATGTATAACACACAGCAAAAAGAGTATGCAGATAACTTGACGTTAATAAGATGTAAGAGCTTCACTTTGACTCCTCTGACTTTTATTATGCTGCTGAAAACATTGTGTTTTAATGTATGTTTTTTTATTGTAGTTCAAATAGGAAAAATAAGGTGGCTATACAACCATGGACACAGAGGAAGTAGCAGCTGAAGCACCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21916
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033914 Nonsense 13 964 1 16
ENSDART00000035629 None None 850 None 15
ENSDART00000124131 Nonsense 13 961 2 17
ENSDART00000147179 Nonsense 13 66 3 3
Genomic Location (Zv9):
Chromosome 11 (position 26494227)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25323052
GRCz11 11 25560668
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGGCTATACAACCATGGACACAGAGGAAGTAGCAGCTGAAGCACCTGCA[G/T]AAACAGCAACCGAGGAAAAAGATGCAACTTCAGAGGAAAACAAAGAGTCC
Long Flanking Sequence:
GTTTTTAAAAATGTCGCCGTCGTATTAATGACTTTTCATGTAACCGAATCACAAAACTCCGCAAATAGTGCAAGAAAACCTCACTATACAGTGTCTTTTGCAATAATTTCACGCTTGCTAGCACATTAGCCACCATGCTAACTATTTGCGCTGATACTTGCTCGGCTGTGTCTCAAAACCTAGCGTGTTGGCTACCTAGAACGCACCAAGAGTCGGGGTTTAGTAAACAAAACATTTGTTTTTTTCTTCCGTAAAGCAACAATAGGCCTTTGAATGCAGATGCGGGTGCCTGTATCGAATGTATAACACACAGCAAAAAGAGTATGCAGATAACTTGACGTTAATAAGATGTAAGAGCTTCACTTTGACTCCTCTGACTTTTATTATGCTGCTGAAAACATTGTGTTTTAATGTATGTTTTTTTATTGTAGTTCAAATAGGAAAAATAAGGTGGCTATACAACCATGGACACAGAGGAAGTAGCAGCTGAAGCACCTGCA[G/T]AAACAGCAACCGAGGAAAAAGATGCAACTTCAGAGGAAAACAAAGAGTCCACGACAAGCACAGACATCCAGGATCATGTCACGGACAAAAACCAAGAGGAAGATGCAGCTGCAAAGGAAGACGAAGAAGCTGTTATTGACAAGGAAGCTGAAGAAGCTGTAATTCAGAAAAAAGATGAAGAAGCAGTAGTTCAGAAGGAAGGTGAAGAAGCTATAATTCAGAAGGAAGGTGAAGAAACTATAGCCGAGAAAGAAGGTGAAGAAACTGTAACCGAGAAAGAAGGTGAAGATGCTGTAACAGAGAAAGAAGGTGAAGAAGCTGAAACCGAAAAAGAAGGTGAAGATGCTGTAACCGAAAAAGAAGGTGAAGATGCTGTAACCGAAAAAGAAGGTAAAGATGCAGTAACCGAGAAAGAAGGTGAAGAAGCTGAAACTGAGAATAAAGGTGAAGAAGCTGAAACGGAGAATAAAGGTGAAGAAGCAGTACTCGAGAAGCAAGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35091
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033914 Nonsense 523 964 7 16
ENSDART00000035629 None None 850 None 15
ENSDART00000124131 Nonsense 523 961 8 17
ENSDART00000147179 None None 66 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26500056)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25328881
GRCz11 11 25566497
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTTAATATCCACTCTCGTAAAGTTGTTAAATGTCGCAAACGGAAATGTT[T/A]ACACCCTGTTCGTAGGGAGAGGGGTTTTAAGGTACAGTGCTATATATTAG
Long Flanking Sequence:
TGGGAAAGTCTGTCTTCACTTTTTTGTACTTTAGAGTCTGCATTAGATGTAATAAAACCTATTCTTATGAAGAAGGACAAACTTTGTGCAAGGACTGCAGGATAGAGAATAGAGCATGTAAGTCAAATGCTATTCATTTAGTTTTGTGAGTGCTGGTTAATAATAAGCTTTATCATAATTTGTGTCATTTTAAATGCATAGTTATTATATTCCTCTTTGTTTTCTTTGTTTTTTGCTTTAGTGGCAAGCAGAAAACCATACAAAAAGGTGACAGTCTTTTTACTTTATGGAATGTTTTGTGTAACCTATTAAGAAATGTATATTTATTTATTGTATTTATTTATGGATTTATTGTTCTTAGTGGGTTCCATGTGGTCGATGCTGGGCTTGTCAAACAACAGTGGACTGTGGGAAATGCGTTAGCTGCAGAAATGGCCGGCTGCGCCATCGACTTAATATCCACTCTCGTAAAGTTGTTAAATGTCGCAAACGGAAATGTT[T/A]ACACCCTGTTCGTAGGGAGAGGGGTTTTAAGGTACAGTGCTATATATTAGCTTTTTAAAAAGTTTTTATCAGTATGATGTTTTTATTAATCTTTTCAGCTTAAAAGGGGATATATTTTCCACTGACAATCATTTAGCTTTCAACAAAACACAATGAAAAAACTTCAATAACGTAAATAATAATAACAGTAGAGATAAAACAATAATGTAAACTATAATAATAACAAAATTGACAAATCAGGAAGGGTCAAATATACACCCAATAGTCAAACTCTTTATTGAATAAAATTAAGTTTTTGTTCTTAATCTAAGGAGGAGACTGTGAGAGAAAGCTTGCTGGTTATTAAATCAGAAAATGCCTACCTTGCAGATTTAAACTTGATGGCAATTAATTTATGCTTCTACGAAACCTGGACCTTACAAATTTGGTCCAGATATTTCTGAATACATTCATTTGAAGGCGAAGGGAAAATGCAATATTTTCTATAGCGTAAAGATCGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21917
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033914 Essential Splice Site 742 964 14 16
ENSDART00000035629 Essential Splice Site 628 850 13 15
ENSDART00000124131 Essential Splice Site 739 961 15 17
ENSDART00000147179 None None 66 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26506158)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25334983
GRCz11 11 25572599
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGAACCGAAGCTACTGTATATAAATGTTGATTTGTCATTTTCTCTCTC[T/A]GGAGACGATGAGTCCTCATGTGCGAACTGGACAGGCGGAGATGATCAAAG
Long Flanking Sequence:
CACATATGGACGAGGTACACCCGGGTCCAAGAAGATGTGGGGTTTTGAGATGTCAGATGATATGCCTGAACAGTACATGCAGAAAAATTCAGCTCACCTGATGAATCAAGACCGATTCCTGCACCCCAGTTACAATGGAAAGGTATTTCAGCAGACTCCTAAAACATCACCACTTAATCATCTTCACTTCCAATAACTTATTTCTGTTTTTATACTTACTGATGAAGGCCTACAGTTATACTGATGTGCCAAACAGTCATATGGTGAACAACATGCCACTCTATAATCCACACAAAGTTGAGGTATGTTCTCAACATAAACATGAAAAAAATCTATACGATAGCTGTAAACTATTAATCAAATCGTGATCATTTCAAAACTACTCTCAAAGCAACAGTCCATTAACAAAATAAAAAGCTAATTCCATTGTCAGAATGCATGTTCTTACTATTTGAACCGAAGCTACTGTATATAAATGTTGATTTGTCATTTTCTCTCTC[T/A]GGAGACGATGAGTCCTCATGTGCGAACTGGACAGGCGGAGATGATCAAAGAAAATGGGCTTCAGAGCATCAGTAACAGAAGCTTTGTGGCTAGGGTAAGCTCCTTATAATTTTCTGTGTTTAAATGAATAAAAACAAGAAAGAAAAAAAGATTAGTGAGTGGGAAATAAGCATAGCTCACCTGAGTGGTAAAAATATTAAAATAAGTTTGGTATTGTGCCTCCTTTCTTTTTTTCCCTTTTCTCTACATGATATTATCAGAAGGCAGACTCAAAGTGACCTCTGATGATAGTATTCATTTCTCTTTTATTTATTTATTTTTTTTTTTTGCCAGCACGTTATCTTGAAAAACCAAGGCGACTGTAACGCATAACCTTTTAGATTATTGTAAATTAACTAAACATTCTGAAAATGAATAACTTTAAAATGCATTTAATGGTAAGAAATTTATGAAGGATCATGTGAAACTGAAAACGGGTAATAATTCAGAAAATTCAGCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41843
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033914 Essential Splice Site 772 964 14 16
ENSDART00000035629 Essential Splice Site 658 850 13 15
ENSDART00000124131 Essential Splice Site 769 961 15 17
ENSDART00000147179 None None 66 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26506254)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25335079
GRCz11 11 25572695
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAAGAAAATGGGCTTCAGAGCATCAGTAACAGAAGCTTTGTGGCTAGGG[T/C]AAGCTCCTTATAATTTTCTGTGTTTAAATGAATAAAAACAAGAAAGAAAA
Long Flanking Sequence:
CCTGATGAATCAAGACCGATTCCTGCACCCCAGTTACAATGGAAAGGTATTTCAGCAGACTCCTAAAACATCACCACTTAATCATCTTCACTTCCAATAACTTATTTCTGTTTTTATACTTACTGATGAAGGCCTACAGTTATACTGATGTGCCAAACAGTCATATGGTGAACAACATGCCACTCTATAATCCACACAAAGTTGAGGTATGTTCTCAACATAAACATGAAAAAAATCTATACGATAGCTGTAAACTATTAATCAAATCGTGATCATTTCAAAACTACTCTCAAAGCAACAGTCCATTAACAAAATAAAAAGCTAATTCCATTGTCAGAATGCATGTTCTTACTATTTGAACCGAAGCTACTGTATATAAATGTTGATTTGTCATTTTCTCTCTCTGGAGACGATGAGTCCTCATGTGCGAACTGGACAGGCGGAGATGATCAAAGAAAATGGGCTTCAGAGCATCAGTAACAGAAGCTTTGTGGCTAGGG[T/C]AAGCTCCTTATAATTTTCTGTGTTTAAATGAATAAAAACAAGAAAGAAAAAAAGATTAGTGAGTGGGAAATAAGCATAGCTCACCTGAGTGGTAAAAATATTAAAATAAGTTTGGTATTGTGCCTCCTTTCTTTTTTTCCCTTTTCTCTACATGATATTATCAGAAGGCAGACTCAAAGTGACCTCTGATGATAGTATTCATTTCTCTTTTATTTATTTATTTTTTTTTTTTGCCAGCACGTTATCTTGAAAAACCAAGGCGACTGTAACGCATAACCTTTTAGATTATTGTAAATTAACTAAACATTCTGAAAATGAATAACTTTAAAATGCATTTAATGGTAAGAAATTTATGAAGGATCATGTGAAACTGAAAACGGGTAATAATTCAGAAAATTCAGCTTTGATGTTACTGCTAAACATTTTACTTTTATATATTTACATTTTATCCTGTATCTATTTATGTGTGTACAGTATGTGTGGTTGTATCTAATATATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21918
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033914 Nonsense 786 964 15 16
ENSDART00000035629 Nonsense 672 850 14 15
ENSDART00000124131 Nonsense 783 961 16 17
ENSDART00000147179 None None 66 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26507481)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25336306
GRCz11 11 25573922
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTATTTACAGAGACCTGACGTTCCTCCTACCACTCAGTTTGACAGCACT[G/T]GAAATCCAGGCTCTAAAACTGAAAGAAACCGATCGCAGGATGAACAATCA
Long Flanking Sequence:
TGGATTTTGTATGTTCTCCACATGTTTCGTTTGGGTTATCTCCAGATGCTCCTGTTTCCCCCACAGTTCAAAGACATGTGGTATAGGTGAATTGGATAAGCTAAATTATCTGTAGTGTACGAGTGTGTGTGAATGTTTCCCAGTGATGGGTTGCAGCTGGAAGGGCATCCGCTGTGTAAAATATATGCTTGATAAGTTGGTGGTTCATTCCGCCATGGTGATCCCAAATTAATAAAGGGACTAAGCCCAAAAGAAAATGAATGAATAATATACTGTAAAAATATTCTCTAAATTCAGAATTTGACAGGGGTATGAATAATTTCAGGCTTAACTTTCTGTATGCGTCTAATGTATGTGTTTGTGTATGTATATGTGTACTGTAAATGTGTGTCTGTGCAGTAATAATTGTATTACAGTAAAGTATTTGCAATTGCTTATTAGTATTTCACATTTATTTACAGAGACCTGACGTTCCTCCTACCACTCAGTTTGACAGCACT[G/T]GAAATCCAGGCTCTAAAACTGAAAGAAACCGATCGCAGGATGAACAATCAGAGGGCGAGTCTTTCCCATCGGTAAGAAGACATTTCACCGATTCTGTCCCAATGATAAGGCTGTTTCATTAAAGTCCACCTGAACCAGACATGGCTGAGACTTATTTCAGTATGTTCATGAACTTACAGTTGAAACGGAATATTGAGTGAGGGGGGCTTTCTTTTGCACATCATAGCATACTAACAGTAAGAGGTGCGTGGTTTAAAATGATTGTAGCTAAAGTTGTGAAACTGACGTCAACAAAGAAGAACCCCCACTACAAACGCTGAACAAGATTGCCTAAACAAAATTAAAAAAAAATCAGTGGATTAACTTGATTGGATTATTAATCACATAAAGAAACAAAATGTAGCTAGTAAAATGAACATTGTAAATTTCCATACAAAGATGTGAATTAAATTTATGTGCAAAACTGGAATTTATAATAAAAGATTTGCGAATAAACCAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31833
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033914 Essential Splice Site 810 964 None 16
ENSDART00000035629 Essential Splice Site 696 850 None 15
ENSDART00000124131 Essential Splice Site 807 961 None 17
ENSDART00000147179 None None 66 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26508598)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25337423
GRCz11 11 25575039
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAATAGGTGGATGGAAACATAGCTAGTGCCCACACTCTTCTTTCTATGAC[A/T]GATCACTCAGATATTCAGCGTGGCAGGCAGCGACCACGCCGTCCAGGGCA
Long Flanking Sequence:
CTGATAAACTGACGGCAAATATCAAAAAGGAAAACAGAGTTTGCTGCAGTTGGAAAAGCTGCGTGAGTGTTTTTCTTGTATCATAAATGACTTGCGCCATTAGAAGACAATGTCGACATGCAATGAGCACGCAGTGGTTTTTGCAGACATTACACTCTCGCTCATGACAGTCCTGAACGTAATAATAATTCTATAATTATAATAATACTTATGATGGACTTTTGGTTAAGGCATTTTAGATTGACTAAATATTTAATGTTTTACAATGTGCTCAGCCTGCTGGTTTATCCATGGACCCTTTTCACATTTCGGGGTTTCTCAGTAGCTGAGGTCGTCATAGCTGGATAATCTTAAAAGCACAGTGAATGGGAGGGCACAACAAAATGCAGTTGTTTTTATGTGCATTTTTTAAAAATCTGTGCGCATCTTGACTTTCCAAAATGAGCTAAAAAATAGGTGGATGGAAACATAGCTAGTGCCCACACTCTTCTTTCTATGAC[A/T]GATCACTCAGATATTCAGCGTGGCAGGCAGCGACCACGCCGTCCAGGGCATGGACGTAAATCACGAACTGATGCCGCTCTTGAGATCTCTACGCAGTATAGTCCTCCCAGTTCTCTGGTTCTGCGTGGTGGTGGAAGGGCCGCGGTTACAGCTGCTGCAGTGCTCCAAACGCTCCACCATGGCGGATACCGTCATCTACATCGAGCCCGGCTTTCACTACCACATCAGCGTCCAGGACCAGCCGCTGCTGCCCACACACAAACTCTACGACTGCCACCCGTCTCGCCTCACCAGCGCGGCTGAGATCATCGCCCTCATCGAGGATCTGGAGAAGCACTCCGTCTGCCAAGGCTCAGAGCACAAACACAGCTCAGACCTGGTGATTCCCGAACGGGCGGCTACTTGTGACTTCCTTATTTCAGCAGAGGTAGAACGCTGTGAGAAATGCCAGACTTTACAAAGGGCGTAGAGAGAAAGAGAAAGCTGGAAATTGCTCTTAT
Associated Phenotype:
Not determined