ZMP
comtb
Ensembl ID:
ZFIN ID:
Description:
catechol O-methyltransferase [Source:RefSeq peptide;Acc:NP_001077312]
Human Orthologue:
COMT
Human Description:
catechol-O-methyltransferase [Source:HGNC Symbol;Acc:2228]
Mouse Orthologue:
Comt1
Mouse Description:
catechol-O-methyltransferase 1 Gene [Source:MGI Symbol;Acc:MGI:88470]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa6209 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa35092 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa6209
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000033702 | Nonsense | 193 | 264 | 5 | 6 |
| ENSDART00000146647 | None | None | 20 | None | 3 |
Genomic Location (Zv9):
Chromosome 11 (position 26563560)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 11 | 25392385 |
| GRCz11 | 11 | 25630001 |
KASP Assay ID:
554-5281.1 (used for ordering genotyping assays)
KASP Sequence:
AAGGAKCACTTTGGAATYGAAACCTTTGATTTAGTTTTTCTGGACCACTG[G/A]AAAGACCATTACCTTCCTGACACTAAATTAATGGAGGTGTGTTTTGACCA
Long Flanking Sequence:
TTTTGTGCTGCATGCATTGGTTGTTTATCTATAGCTGACCAGATGGAGCCTTTGCTATCTTCATCAACTTCAGGTTAAGGTGCAATAAACACTAATGCTGGGAGTGGAAAATATCAACAAAGAGAATCAGAGTTTCTGAAGGTTTCAGTCTTTCAGTGTTTTAGCGTCTCCTCGGCTGATAAAATAGTGTTTTAAAAGTTAGTTGTGTCATAATAAATATCGTTAAAGCAACACTCAATAATATCATCACATATTTCCCATTATTCCCAGTACATATTTCCCAGAGTAGATTTACTTTAAATAAGCCTGCAGTGATGTGAAAAATTCTAAAATTGAATGTTGTTCTCTAATTTGCTAATAAAGGTATTATTGTAAAAGCCTAACAGGTATTTTTCACTTCATCAGGTGCAGCTTGTAGAAGGTGCGTCTGAAGACTGGATCCCACGCATGAAGGAGCACTTTGGAATCGAAACCTTTGATTTAGTTTTTCTGGACCACTG[G/A]AAAGACCATTACCTTCCTGACACTAAATTAATGGAGGTGTGTTTTGACCATTTCATCTGCAGATATCAGAAATCTTGAATTTGCCGCTAAATCCTTCTGTCTCTCCTTTTCTGTCTACTTTCTTCACAGGGTTGTGGTCTGCTAAGGAAAGGCACGGTTCTTCTTGCTGATAATGTGATCTGTCCTGGAGTCCCAGACTATCTTGAATATGTGCGCAATAGCCGTTCCTATAAAAGCTGCTATTTTAAATCCCATTTAGAGTACACCAGGGCAGAGGATGGCTTGGAGAAGTCTGTGTTTTTGGGCTAGAGATGTACAGAGATGATTCTTATGCTTAAAAGGAGGATTTTTTTTCTTTTCTGAGAGCCAGTGTGAGGTTTATTTTAAATGATTTATTATTATAAGTCCCCTACACTCTTCAAACACTTGGTTGTTTTAAACCAAATTTAGATAAAATATGAACAAACTGTAACAATGGGTTAAAGGCGTAGTAAACCCAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa35092
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000033702 | Nonsense | 239 | 264 | 6 | 6 |
| ENSDART00000146647 | None | None | 20 | None | 3 |
Genomic Location (Zv9):
Chromosome 11 (position 26563791)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 11 | 25392616 |
| GRCz11 | 11 | 25630232 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTCCTGGAGTCCCAGACTATCTTGAATATGTGCGCAATAGCCGTTCCTA[T/G]AAAAGCTGCTATTTTAAATCCCATTTAGAGTACACCAGGGCAGAGGATGG
Long Flanking Sequence:
CACTCAATAATATCATCACATATTTCCCATTATTCCCAGTACATATTTCCCAGAGTAGATTTACTTTAAATAAGCCTGCAGTGATGTGAAAAATTCTAAAATTGAATGTTGTTCTCTAATTTGCTAATAAAGGTATTATTGTAAAAGCCTAACAGGTATTTTTCACTTCATCAGGTGCAGCTTGTAGAAGGTGCGTCTGAAGACTGGATCCCACGCATGAAGGAGCACTTTGGAATCGAAACCTTTGATTTAGTTTTTCTGGACCACTGGAAAGACCATTACCTTCCTGACACTAAATTAATGGAGGTGTGTTTTGACCATTTCATCTGCAGATATCAGAAATCTTGAATTTGCCGCTAAATCCTTCTGTCTCTCCTTTTCTGTCTACTTTCTTCACAGGGTTGTGGTCTGCTAAGGAAAGGCACGGTTCTTCTTGCTGATAATGTGATCTGTCCTGGAGTCCCAGACTATCTTGAATATGTGCGCAATAGCCGTTCCTA[T/G]AAAAGCTGCTATTTTAAATCCCATTTAGAGTACACCAGGGCAGAGGATGGCTTGGAGAAGTCTGTGTTTTTGGGCTAGAGATGTACAGAGATGATTCTTATGCTTAAAAGGAGGATTTTTTTTCTTTTCTGAGAGCCAGTGTGAGGTTTATTTTAAATGATTTATTATTATAAGTCCCCTACACTCTTCAAACACTTGGTTGTTTTAAACCAAATTTAGATAAAATATGAACAAACTGTAACAATGGGTTAAAGGCGTAGTAAACCCAAAAATTTAAATCCCATCAGTATTACTTGAACTTCATCTGTTAGAGTTTATTTCTTGTCTTGAACACAAAAGAAGATACTTAGCAAACATTTGGGAAACTGGTAGACATTGACTTCTGTAGTGTATTATTAATTCATTAATTTTCTTTTTGGCTTAGTCCCTATATTATTTAGGGGTCGCCACGGCGGAATGAATCGCCAACCTATCCAGCATATGTTTTACGCAGCGGATGC
Associated Phenotype:
Not determined