Busch Lab

ZMP

comtb

Ensembl ID:
ENSDARG00000025679
ZFIN ID:
ZDB-GENE-040724-164
Description:
catechol O-methyltransferase [Source:RefSeq peptide;Acc:NP_001077312]
Human Orthologue:
COMT
Human Description:
catechol-O-methyltransferase [Source:HGNC Symbol;Acc:2228]
Mouse Orthologue:
Comt1
Mouse Description:
catechol-O-methyltransferase 1 Gene [Source:MGI Symbol;Acc:MGI:88470]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa6209 Nonsense Mutation detected in F1 DNA Not yet available
sa35092 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa6209
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033702 Nonsense 193 264 5 6
ENSDART00000146647 None None 20 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26563560)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25392385
GRCz11 11 25630001
KASP Assay ID:
554-5281.1 (used for ordering genotyping assays)
KASP Sequence:
AAGGAKCACTTTGGAATYGAAACCTTTGATTTAGTTTTTCTGGACCACTG[G/A]AAAGACCATTACCTTCCTGACACTAAATTAATGGAGGTGTGTTTTGACCA
Long Flanking Sequence:
TTTTGTGCTGCATGCATTGGTTGTTTATCTATAGCTGACCAGATGGAGCCTTTGCTATCTTCATCAACTTCAGGTTAAGGTGCAATAAACACTAATGCTGGGAGTGGAAAATATCAACAAAGAGAATCAGAGTTTCTGAAGGTTTCAGTCTTTCAGTGTTTTAGCGTCTCCTCGGCTGATAAAATAGTGTTTTAAAAGTTAGTTGTGTCATAATAAATATCGTTAAAGCAACACTCAATAATATCATCACATATTTCCCATTATTCCCAGTACATATTTCCCAGAGTAGATTTACTTTAAATAAGCCTGCAGTGATGTGAAAAATTCTAAAATTGAATGTTGTTCTCTAATTTGCTAATAAAGGTATTATTGTAAAAGCCTAACAGGTATTTTTCACTTCATCAGGTGCAGCTTGTAGAAGGTGCGTCTGAAGACTGGATCCCACGCATGAAGGAGCACTTTGGAATCGAAACCTTTGATTTAGTTTTTCTGGACCACTG[G/A]AAAGACCATTACCTTCCTGACACTAAATTAATGGAGGTGTGTTTTGACCATTTCATCTGCAGATATCAGAAATCTTGAATTTGCCGCTAAATCCTTCTGTCTCTCCTTTTCTGTCTACTTTCTTCACAGGGTTGTGGTCTGCTAAGGAAAGGCACGGTTCTTCTTGCTGATAATGTGATCTGTCCTGGAGTCCCAGACTATCTTGAATATGTGCGCAATAGCCGTTCCTATAAAAGCTGCTATTTTAAATCCCATTTAGAGTACACCAGGGCAGAGGATGGCTTGGAGAAGTCTGTGTTTTTGGGCTAGAGATGTACAGAGATGATTCTTATGCTTAAAAGGAGGATTTTTTTTCTTTTCTGAGAGCCAGTGTGAGGTTTATTTTAAATGATTTATTATTATAAGTCCCCTACACTCTTCAAACACTTGGTTGTTTTAAACCAAATTTAGATAAAATATGAACAAACTGTAACAATGGGTTAAAGGCGTAGTAAACCCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35092
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000033702 Nonsense 239 264 6 6
ENSDART00000146647 None None 20 None 3
Genomic Location (Zv9):
Chromosome 11 (position 26563791)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 25392616
GRCz11 11 25630232
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTCCTGGAGTCCCAGACTATCTTGAATATGTGCGCAATAGCCGTTCCTA[T/G]AAAAGCTGCTATTTTAAATCCCATTTAGAGTACACCAGGGCAGAGGATGG
Long Flanking Sequence:
CACTCAATAATATCATCACATATTTCCCATTATTCCCAGTACATATTTCCCAGAGTAGATTTACTTTAAATAAGCCTGCAGTGATGTGAAAAATTCTAAAATTGAATGTTGTTCTCTAATTTGCTAATAAAGGTATTATTGTAAAAGCCTAACAGGTATTTTTCACTTCATCAGGTGCAGCTTGTAGAAGGTGCGTCTGAAGACTGGATCCCACGCATGAAGGAGCACTTTGGAATCGAAACCTTTGATTTAGTTTTTCTGGACCACTGGAAAGACCATTACCTTCCTGACACTAAATTAATGGAGGTGTGTTTTGACCATTTCATCTGCAGATATCAGAAATCTTGAATTTGCCGCTAAATCCTTCTGTCTCTCCTTTTCTGTCTACTTTCTTCACAGGGTTGTGGTCTGCTAAGGAAAGGCACGGTTCTTCTTGCTGATAATGTGATCTGTCCTGGAGTCCCAGACTATCTTGAATATGTGCGCAATAGCCGTTCCTA[T/G]AAAAGCTGCTATTTTAAATCCCATTTAGAGTACACCAGGGCAGAGGATGGCTTGGAGAAGTCTGTGTTTTTGGGCTAGAGATGTACAGAGATGATTCTTATGCTTAAAAGGAGGATTTTTTTTCTTTTCTGAGAGCCAGTGTGAGGTTTATTTTAAATGATTTATTATTATAAGTCCCCTACACTCTTCAAACACTTGGTTGTTTTAAACCAAATTTAGATAAAATATGAACAAACTGTAACAATGGGTTAAAGGCGTAGTAAACCCAAAAATTTAAATCCCATCAGTATTACTTGAACTTCATCTGTTAGAGTTTATTTCTTGTCTTGAACACAAAAGAAGATACTTAGCAAACATTTGGGAAACTGGTAGACATTGACTTCTGTAGTGTATTATTAATTCATTAATTTTCTTTTTGGCTTAGTCCCTATATTATTTAGGGGTCGCCACGGCGGAATGAATCGCCAACCTATCCAGCATATGTTTTACGCAGCGGATGC
Associated Phenotype:
Not determined