Busch Lab

ZMP

brd8

Ensembl ID:
ENSDARG00000025071
ZFIN ID:
ZDB-GENE-030722-10
Description:
Bromodomain containing 8 [Source:UniProtKB/TrEMBL;Acc:Q6PFM2]
Human Orthologue:
BRD8
Human Description:
bromodomain containing 8 [Source:HGNC Symbol;Acc:19874]
Mouse Orthologues:
4933408B17Rik, Brd8
Mouse Descriptions:
RIKEN cDNA 4933408B17 gene Gene [Source:MGI Symbol;Acc:MGI:3045347]
bromodomain containing 8 Gene [Source:MGI Symbol;Acc:MGI:1925906]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa31973 Essential Splice Site Available for shipment Available now
sa265 Nonsense Confirmed mutation in F2 line Not yet available
sa15090 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa31973
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028623 Essential Splice Site None 840 1 19
ENSDART00000123139 None None 849 None 19

The following transcripts of ENSDARG00000025071 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 7665892)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 7391371
GRCz11 14 7697780
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACATCGACAGTCCGGGCGCCGACGAACTAAAAAGAAACACAAAAGAAGG[T/A]AAGTTTATAATCATTTTGTTTATTTTGAAACTTTTTTGTTGTATATTGAG
Long Flanking Sequence:
GAAGTAACTTGAGTCAAACTTATTAAAAAGTTTGTTCATCATCGTGAAGTAAATGTAAATCTCATTTGATTTGTGATCTCGTCGTAATTTTATAACGAACTCCAAGAGGGTCACCATCCCAGTTGCTCAAAGAAGATTATTAACATAACAACAACAACAACAATAGTACAAATAATAATAATAAAAACAATAACAATAATAATAATTATTATTATTATTGTTTATAATGTATATTATTAACTTACACATATATAAATAAAACTATAACATGTAGATATAAATATTTAATCATAAAATTGCATTACGTACACGGTGAAACCAGAGAAGGCTAGCACACGTGACCTGCCATTCTCCAATCATCATCTGTACACGCGCTCGCGGCCTGGGTCACCTCATGTTCACCCCTTAATGAGTGTGACGTCAAATTGATGGACCCTAAACCTGGCGAGAGACATCGACAGTCCGGGCGCCGACGAACTAAAAAGAAACACAAAAGAAGG[T/A]AAGTTTATAATCATTTTGTTTATTTTGAAACTTTTTTGTTGTATATTGAGGTCTTGATTGGTGTTAATGTCGGTAACGTTAATTTAACCGCGCTAATGTTATCTGCCGTTCGGCCTTAAACTCAATCTACGATTCCGTGTTTCTTTATGAAATGTGTTATATATAACATACAAAATGCCAATAATAGACAAATAATGCAAATAATCATTTACTAAGACGGTTTTGTTGTTGTTGTAAACGAGCCTGTTAGGCGATTGAGGTAAAGCTGTCTTTATTCGCACATTCTCCTTAATAATATAATATAAGAAAAGTATTACTTGCAAATTCTAAATCGGGAAATTATATGATCAGCCAATGACTATCGAAGTACAACATTGTTCGCAGTCAACTAGATAGTGGTAATGAAGTCATGCATGCGATGTCAGTCCGAATAACTTATTTAACGTTAGTGTAAGGCCCCTCGACGCATGTGCCATTATAAAACCAACTTTACCTCAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa265
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028623 Nonsense 443 840 13 19
ENSDART00000123139 Nonsense 452 849 13 19

The following transcripts of ENSDARG00000025071 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 7685694)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 7411173
GRCz11 14 7717582
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCCCTCTGTGAGGATCCAGCAGTCGGAGGTCACCCCCTCACCAGCCCCT[G/A]GGAATCACAGACATTTAAGGCAGCCGAACCAGAGCCTATGATCCAGCAGA
Long Flanking Sequence:
AGTAAGTGTATTTATGAACATACTATAACCTGCTGCTTTACTCCAGAGAACTCAAAATAACAGCAAGAAACGCTTTTGCACAGGCCGATCTAAAGGGTAATGCTGCCAACTGATGATCAGCAGTAAAACTGAGACTTCCCAACAGGGAAAACCACCAATAATCAAGAATGCATAATTAAATGGTGTCATGGCTTTGCAGTCAAAAAAGTAATTTCTAGTAGAAGTCATTTAGGCAAAAACAGCCACCAACATAACGAAAGGGTGGTCAATCAGTACACAAGGGTTAAATAATAAATAATTATTCACAGTATTTTAAAGTGCCCACCATATCAATATTGTGCATCACTGTATATTGAATGATTACATATCAACATGTCTGAAAGCATTACCTCTATTTCAGGTGGACGACCCTGTGGAGGCTCTGGACGCAGCGGCAGTGGAGGCAGCTCTCTCCCTCTGTGAGGATCCAGCAGTCGGAGGTCACCCCCTCACCAGCCCCT[G/A]GGAATCACAGACATTTAAGGCAGCCGAACCAGAGCCTATGATCCAGCAGAGTGCCATCCCAGCGGGCGCAGAGAGTGCCCCGAACTCTGCAATTGTGCAGGGAGAAATGGAGGTTCTGGTAGAAGAGGCTACAGAAACCGAAGCAGTTGAGGGAGTGACAGAGGAGCCTGAGGTGCCCTCTGCCCCGGAAACAGAGCAGAGCCAGGACTCAGAGGTTAAGACAGAGGTCGAGAGGGGAGGAGAGGGTGAAGGGGGTGTGGAGGAAACAGCGCAGCCGGAGAACAGAACACCGAGTCCAGCTGTGAAGTGTGAAGGGGAGGACTGGGTTCAGCCAGAGACCGTGACACCCTGTCTGGATTCAGAAGATAGCTCGGCCTCAGCAAAAGATGCAAAGGTATTAGCAAAGCAAAATGAAAAGTATGCCTTTATGTACAATGCTAATCAAAAGTATTTTTTAATTGACATGACTAATTTATAAGTTGTATAACAATAAAATCGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15090
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000028623 Essential Splice Site 574 840 13 19
ENSDART00000123139 Essential Splice Site 583 849 13 19

The following transcripts of ENSDARG00000025071 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 14 (position 7686089)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 7411568
GRCz11 14 7717977
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
YWCCCTGTCTGGATTCAGAAGATAGCTCGGCCTCAGCAAAAGATGYAAAG[G/A]TATYAGCAAAGCAAAAKGAAAAGTATGCCTTTATGTACAATGCTRWTCAA
Long Flanking Sequence:
TTCAGGTGGACGACCCTGTGGAGGCTCTGGACGCAGCGGCAGTGGAGGCAGCTCTCTCCCTCTGTGAGGATCCAGCAGTCGGAGGTCACCCCCTCACCAGCCCCTGGGAATCACAGACATTTAAGGCAGCCGAACCAGAGCCTATGATCCAGCAGAGTGCCATCCCAGCGGGCGCAGAGAGTGCCCCGAACTCTGCAATTGTGCAGGGAGAAATGGAGGTTCTGGTAGAAGAGGCTACAGAAACCGAAGCAGTTGAGGGAGTGACAGAGGAGCCTGAGGTGCCCTCTGCCCCGGAAACAGAGCAGAGCCAGGACTCAGAGGTTAAGACAGAGGTCGAGAGGGGAGGAGAGGGTGAAGGGGGTGTGGAGGAAACAGCGCAGCCGGAGAACAGAACACCGAGTCCAGCTGTGAAGTGTGAAGGGGAGGACTGGGTTCAGCCAGAGACCGTGACACCCTGTCTGGATTCAGAAGATAGCTCGGCCTCAGCAAAAGATGCAAAG[G/A]TATTAGCAAAGCAAAATGAAAAGTATGCCTTTATGTACAATGCTAATCAAAAGTATTTTTTAATTGACATGACTAATTTATAAGTTGTATAACAATAAAATCGAGCCAGTCATAGCGAAATGCCCAGCACAGCTTATCAACAATATAGAAGTAGTCAGAGTGCATAGTGCATGTGTGAGCATACCTGCGGTTAATTTAACCGGCGTCTGCTACAGCGTGTGTCTTTGCTACTGTGCTAGTAGGCGGGACCGCAGGTTTCGATTTTCCTGGGTTTGCACGCGCAGCAACTGGGCTGAGCTTAAGTTTCGTATCCATGTCACGCCTTAGCGTTCATTTGAAGTACTAGGAGTCGACCCTTTTATAAATGAATCAATAGTTTTAAACACTTTCCACTCTCAGATTTAAGCCTTAGCTGGACATTTTACTTTACTTAGAGCTTTTATGCACTACATGGATGGTAAGGGTGTCACGATCCTCCAAATCCTCGATTCGATTACATT
Associated Phenotype:
Not determined