ZMP
c6ast3
Ensembl ID:
ZFIN ID:
Description:
six-cysteine containing astacin protease 3 [Source:RefSeq peptide;Acc:NP_001013544]
Human Orthologue:
ASTL
Human Description:
astacin-like metallo-endopeptidase (M12 family) [Source:HGNC Symbol;Acc:31704]
Mouse Orthologue:
Astl
Mouse Description:
astacin-like metalloendopeptidase (M12 family) Gene [Source:MGI Symbol;Acc:MGI:3046414]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa40959 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa38629 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa40959
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000030900 | Nonsense | 64 | 254 | 4 | 9 |
| ENSDART00000114934 | Nonsense | 65 | 255 | 5 | 10 |
Genomic Location (Zv9):
Chromosome 7 (position 40035797)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 38372437 |
| GRCz11 | 7 | 38643695 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGGACGACATTGCTGTGAATGAGAAAAATGCTGATCCCTGCACCTCCTA[C/A]GGCTGTCTCTGGCCCAAATACAGTGATGGCAAGATTTATGTGCCTTACGT
Long Flanking Sequence:
TAAAAATTTGTAAACGATGCATGGTTTTGTATACTATAATATAAAATAATATGCAAAAAATGTTTTGACATTACCTAATATTTATTATCCATTTTGTGTTGGGTGTTCTGGCATAACTCACATCCAGCCTGGTAAGTGAAATGCCTAATTTAGCTACTTACCTAATTTAGCAAAGAGAATGTAAAAGCGTTTTAGAAGAAACAAATGAAACAACAAATATTGAGATTTTCTTTTTAACTGAAGCAATGGTTCATTGGTGAATGTGTTGACTTGTTTTTTATAATAGCTCAGCTGTCTGTGTCTGAACTGCTGCATAGAGCCAACAGAGGCATCAGTGCGTATACAACACTTACTCAGCAATACACATCAGTATATCTCAACTGTTCATTACTGAAAGACCCAAAATGACCTGTTCATGTTTTAGTTCCTGAAGCTGATGAGCCCAAGCTCCTGGACGACATTGCTGTGAATGAGAAAAATGCTGATCCCTGCACCTCCTA[C/A]GGCTGTCTCTGGCCCAAATACAGTGATGGCAAGATTTATGTGCCTTACGTCATCGCCAACCACTACTGTAAGTCATTAATTACACAGAAAAAAAGTAGGCCAAATACAGAACTCTTGCTGAATGCATGAAAATGCCTTTAGAATGCTAAATTAAAGGGACAGTTCACAAACAAAAAGACAATTCTGTCACATTCACCCCCACTTATAAACCTGAATTACTTTTTCTCCTGTCAAACACAAAAGAAAAGATTTGTAAACCGGTAACCATCGACTTACATCAACATTACTCAAAATATCTTCTCTTGTGTTTAACAGAAAAACAAAACTCATTCTCTCGGATTCCATTAATAATGAAAAAAAATTACCTTTTCATAGTAGCAACCTCTGACTTTTGCCCTTTCAGCCTCCCGTGAGCTGGAGATCATCCAGCGTGGACTGGACTCTTTCTCTTACAGTACTTGTATCCGCTTCTTCCCTCGCGGCAATGAGAGAGACTACAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38629
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000030900 | Essential Splice Site | 86 | 254 | 4 | 9 |
| ENSDART00000114934 | Essential Splice Site | 87 | 255 | 5 | 10 |
Genomic Location (Zv9):
Chromosome 7 (position 40035729)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 38372369 |
| GRCz11 | 7 | 38643627 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATACAGTGATGGCAAGATTTATGTGCCTTACGTCATCGCCAACCACTACT[G/T]TAAGTCATTAATTACACAGAAAAAAAGTAGGCCAAATACAGAACTCTTGC
Long Flanking Sequence:
CATTACCTAATATTTATTATCCATTTTGTGTTGGGTGTTCTGGCATAACTCACATCCAGCCTGGTAAGTGAAATGCCTAATTTAGCTACTTACCTAATTTAGCAAAGAGAATGTAAAAGCGTTTTAGAAGAAACAAATGAAACAACAAATATTGAGATTTTCTTTTTAACTGAAGCAATGGTTCATTGGTGAATGTGTTGACTTGTTTTTTATAATAGCTCAGCTGTCTGTGTCTGAACTGCTGCATAGAGCCAACAGAGGCATCAGTGCGTATACAACACTTACTCAGCAATACACATCAGTATATCTCAACTGTTCATTACTGAAAGACCCAAAATGACCTGTTCATGTTTTAGTTCCTGAAGCTGATGAGCCCAAGCTCCTGGACGACATTGCTGTGAATGAGAAAAATGCTGATCCCTGCACCTCCTACGGCTGTCTCTGGCCCAAATACAGTGATGGCAAGATTTATGTGCCTTACGTCATCGCCAACCACTACT[G/T]TAAGTCATTAATTACACAGAAAAAAAGTAGGCCAAATACAGAACTCTTGCTGAATGCATGAAAATGCCTTTAGAATGCTAAATTAAAGGGACAGTTCACAAACAAAAAGACAATTCTGTCACATTCACCCCCACTTATAAACCTGAATTACTTTTTCTCCTGTCAAACACAAAAGAAAAGATTTGTAAACCGGTAACCATCGACTTACATCAACATTACTCAAAATATCTTCTCTTGTGTTTAACAGAAAAACAAAACTCATTCTCTCGGATTCCATTAATAATGAAAAAAAATTACCTTTTCATAGTAGCAACCTCTGACTTTTGCCCTTTCAGCCTCCCGTGAGCTGGAGATCATCCAGCGTGGACTGGACTCTTTCTCTTACAGTACTTGTATCCGCTTCTTCCCTCGCGGCAATGAGAGAGACTACATCAGCATTGAATCTCGCAGCGGGTACGTGACAGATCTTAAACCTAATGCAAAGAGACAACACAAAAGTC
Associated Phenotype:
Not determined