Busch Lab

ZMP

narf

Ensembl ID:
ENSDARG00000024184
ZFIN ID:
ZDB-GENE-040718-31
Description:
Nuclear prelamin A recognition factor [Source:UniProtKB/Swiss-Prot;Acc:Q6DHP6]
Human Orthologue:
NARF
Human Description:
nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:29916]
Mouse Orthologue:
Narf
Mouse Description:
nuclear prelamin A recognition factor Gene [Source:MGI Symbol;Acc:MGI:1914858]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa35338 Splice Site, Nonsense Mutation detected in F1 DNA Not yet available
sa27988 Nonsense Mutation detected in F1 DNA Not yet available
sa22143 Nonsense Available for shipment Available now
sa6266 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa35338
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007053 Splice Site, Nonsense 20 465 3 12
ENSDART00000142716 Splice Site, Nonsense 20 131 3 5

The following transcripts of ENSDARG00000024184 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 34960155)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 33364264
GRCz11 12 33465247
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATTGCTTAAACACTCATTGTGGTTTATTTTCTGTTCCACTTTATAGTG[C/A]AACAAGAAACAAAGTGATGAAAGTATAAACTCACTTCAAGAGAAAGGTGT
Long Flanking Sequence:
AGATTGATTTTGATATTTCTGTATAGAAGTGCATAAAATATAATAAATAATCTACAAGCGTTGATAAATTCATTAAAGAAAAAGTTACAAATTATGTAAACATTGTTTTCTGACAAGTCAAACTGTATTTATGTAAACAGCAATTAAATAATCAAATGTAAAATAAAACCACATAGTCTTCATTTTATACACAATTCAATGAAATGTATGGTGAACAATTTGTAATACTTTTGTAAATATCTGTTAATAATAAGTTACAAATGGTGCAGTTTCATACGATTCAATGTTTAAAAATCCTCACACAGTCACAGGCCTCAAAAAACACTTGCAGAATGATCAGTTATAATCCAGACTCAACATTGCATATACTGACGATGTGACTATTGCGAATGGTCACGTTGCTATATTAATGCTGAAACGATATATTGTGCAGGCCTACTTGTAACCTTTGTATTGCTTAAACACTCATTGTGGTTTATTTTCTGTTCCACTTTATAGTG[C/A]AACAAGAAACAAAGTGATGAAAGTATAAACTCACTTCAAGAGAAAGGTGTTGCCAGTGGAGAGGTACTCTATTGTCTTTTATTTTATATACTTTGTGTATCAGACACAGTGCAATCTGATAAGCTGCGGTCTGCATCTGTTGTTTTGTTTGTGTTTGTATTGGGGTTGGATGAAGAAATGCAAACCTCATTTGTTTTGGACGCGTGCATAATCTGATACGTGAATTTATTTGTTTTTCGTCCCAGGTGAGAGAGTCTACCTCAGTTCAGCAGGTGTTGCTGAGTGCGTGTCTGTCCTGTGACGGCTGTATATCGGAGGATGAAGGCAAGAGAATATCACAGCAGAATCTGGACGAGATCAATCACGTGCTTGCTCTCAACAAGGTAGCGTTTGCCTGTCATGGATTTGGAAAGATGGTTTGTTGATGTATCTTACATTTGTCTTTTTATTTTTGGCAGAAATGTGACACTTCGAAGCACAAAATTCTCGTAGTGTCCGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa27988
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007053 Nonsense 74 465 4 12
ENSDART00000142716 Nonsense 74 131 4 5

The following transcripts of ENSDARG00000024184 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 34960497)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 33364606
GRCz11 12 33465589
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTCCTGTGACGGCTGTATATCGGAGGATGAAGGCAAGAGAATATCACAG[C/T]AGAATCTGGACGAGATCAATCACGTGCTTGCTCTCAACAAGGTAGCGTTT
Long Flanking Sequence:
ATAATCCAGACTCAACATTGCATATACTGACGATGTGACTATTGCGAATGGTCACGTTGCTATATTAATGCTGAAACGATATATTGTGCAGGCCTACTTGTAACCTTTGTATTGCTTAAACACTCATTGTGGTTTATTTTCTGTTCCACTTTATAGTGCAACAAGAAACAAAGTGATGAAAGTATAAACTCACTTCAAGAGAAAGGTGTTGCCAGTGGAGAGGTACTCTATTGTCTTTTATTTTATATACTTTGTGTATCAGACACAGTGCAATCTGATAAGCTGCGGTCTGCATCTGTTGTTTTGTTTGTGTTTGTATTGGGGTTGGATGAAGAAATGCAAACCTCATTTGTTTTGGACGCGTGCATAATCTGATACGTGAATTTATTTGTTTTTCGTCCCAGGTGAGAGAGTCTACCTCAGTTCAGCAGGTGTTGCTGAGTGCGTGTCTGTCCTGTGACGGCTGTATATCGGAGGATGAAGGCAAGAGAATATCACAG[C/T]AGAATCTGGACGAGATCAATCACGTGCTTGCTCTCAACAAGGTAGCGTTTGCCTGTCATGGATTTGGAAAGATGGTTTGTTGATGTATCTTACATTTGTCTTTTTATTTTTGGCAGAAATGTGACACTTCGAAGCACAAAATTCTCGTAGTGTCCGTGTGTCCACAGTCGGTGCCATTTTTTGCTGTTAAATTTCAGTTGGACGTTTCAGCAGCTGCACAGAAACTTTGTGGCTTCCTCAAGAGTGTGGGTACGTCTGGACGCCATATTTCATCTTTCTACATCCAGCTGGTTTTTCTGTTTTTAACCGAGTCAAGATGTGCACATTGCAAATATTTACTGCAATGCAGTCTATGCTCATTTGCACATATTAGGTTTATTTTAGTATCGTTTCTAATATTATTTTATATTGGCTTATATATTAAGTTAATTTTATTAAAGTATCAGAAACGCCAGTTCCCTGGACTGTTTTAAGAAACTTCTCAAAACTCATCTTTTTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22143
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007053 Nonsense 122 465 5 12
ENSDART00000142716 Nonsense 122 131 5 5

The following transcripts of ENSDARG00000024184 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 34960716)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 33364825
GRCz11 12 33465808
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGGTGCCATTTTTTGCTGTTAAATTTCAGTTGGACGTTTCAGCAGCTGCA[C/T]AGAAACTTTGTGGCTTCCTCAAGAGTGTGGGTACGTCTGGACGCCATATT
Long Flanking Sequence:
GAGGTACTCTATTGTCTTTTATTTTATATACTTTGTGTATCAGACACAGTGCAATCTGATAAGCTGCGGTCTGCATCTGTTGTTTTGTTTGTGTTTGTATTGGGGTTGGATGAAGAAATGCAAACCTCATTTGTTTTGGACGCGTGCATAATCTGATACGTGAATTTATTTGTTTTTCGTCCCAGGTGAGAGAGTCTACCTCAGTTCAGCAGGTGTTGCTGAGTGCGTGTCTGTCCTGTGACGGCTGTATATCGGAGGATGAAGGCAAGAGAATATCACAGCAGAATCTGGACGAGATCAATCACGTGCTTGCTCTCAACAAGGTAGCGTTTGCCTGTCATGGATTTGGAAAGATGGTTTGTTGATGTATCTTACATTTGTCTTTTTATTTTTGGCAGAAATGTGACACTTCGAAGCACAAAATTCTCGTAGTGTCCGTGTGTCCACAGTCGGTGCCATTTTTTGCTGTTAAATTTCAGTTGGACGTTTCAGCAGCTGCA[C/T]AGAAACTTTGTGGCTTCCTCAAGAGTGTGGGTACGTCTGGACGCCATATTTCATCTTTCTACATCCAGCTGGTTTTTCTGTTTTTAACCGAGTCAAGATGTGCACATTGCAAATATTTACTGCAATGCAGTCTATGCTCATTTGCACATATTAGGTTTATTTTAGTATCGTTTCTAATATTATTTTATATTGGCTTATATATTAAGTTAATTTTATTAAAGTATCAGAAACGCCAGTTCCCTGGACTGTTTTAAGAAACTTCTCAAAACTCATCTTTTTATTATTGCTTATAACTTATGAGGCCTTCTTGTAATATGTATATTTTTAGCATTATTATCATTCTTACTTTTTTGTGTATTTCATGTTCTTCTGTGTGTTGATGCTCTTGTTAGCGCTTTGAGTTTGAGAAAAGCGCAATATAAATAAAATGTATTATTATTATTATTATTATTATTTTATTATATTACTTTATTAATGTTAAAGTTTTAATATCGTTTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6266
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007053 Essential Splice Site 176 465 6 12
ENSDART00000142716 None None 131 None 5

The following transcripts of ENSDARG00000024184 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 34962478)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 33366587
GRCz11 12 33467570
KASP Assay ID:
554-5169.1 (used for ordering genotyping assays)
KASP Sequence:
TAAACATCATGACGCTAATGCTATGCCTATGTTCACATCCTCCTGTCCAG[G/A]TAAGACAATYCTGATTCAAGTATATGCTCTTTTACRTCTCTTAAAGTAGG
Long Flanking Sequence:
AGCAATATTTCTCTATTTATTTATTTATTTATTTATTTATTTAATTTTTTAAAGCTTGTGTCAGTCCCTGAGCAATATTTTTCTATTTATTTATTTTGTTTTATTTAAACTTGTGTCAGTCCCTGAGCAATAGTTTTCTATTTATTTATTTATTTTATTTTATTTTTAATCTTGTGTCAGTCCCTGAGCAATATTTTTCTATTTTATAATTTTTTTAAATTATTTGTTTTTAAGCAAATTTTTATTTAATTGTATTTTATGCTAATATTATATATCTAACTTTACTTGACTATAAAACCCATTTAACATGTGAGACATGATTTATTTGATTCCATTTTAAAGGTTTCTTTTATCTGTCTCCTCAGGGGTTCATTATGTCTTTGACACCACCATAGCTGCAAGTTTTAGCATTTTGGAAAGCCAGAGAGAATTTGTTCAGCGCTATCGTCGTAAACATCATGACGCTAATGCTATGCCTATGTTCACATCCTCCTGTCCAG[G/A]TAAGACAATCCTGATTCAAGTATATGCTCTTTTACATCTCTTAAAGTAGGAATACACTAATTTTACTCCACATCGCATGTTCTTTTATTAAATCTGTATTGGCTAATTGAATCATTAGGTTTGAATCAAAAAGAAAGGTTGCATCTGGGCACATGTGCAACCTGCAAGACAAAATAAGCATCCCTTATTTTTCTGTCTGAACGTCAAGTCTTAGTGTTTCTCATAACATTTCATCTCTTGGATAAGTTAAATGCAGTGCAGTTGTGTGTGAATGGGTGGGACTGGGTTAGATAGCCATAGCATTCTGCAGCTGTGAGATAGATGAGTGTACGCCACTTTACACACCCTTCCTGCTCTCCTCATAGCTTTCCTCCTTACCCCCAGAGCAGTGTTTGTTACTCATGAATGATTATTAACTCATTAAGCTAATGTGTTTACCAGATGCCTTTTACAATACATTTAACTTAGTCCTATCTGGTGAGGAGACCTGTTGATGCAAT
Associated Phenotype:
Not determined