Busch Lab

ZMP

llgl2

Ensembl ID:
ENSDARG00000023920
ZFIN ID:
ZDB-GENE-030131-9877
Description:
Lethal(2) giant larvae protein homolog 2 [Source:UniProtKB/Swiss-Prot;Acc:Q7SZE3]
Human Orthologue:
LLGL2
Human Description:
lethal giant larvae homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:6629]
Mouse Orthologue:
Llgl2
Mouse Description:
lethal giant larvae homolog 2 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1918843]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa31887 Nonsense Available for shipment Available now
sa38900 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa31887
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000034550 Nonsense 373 1020 11 26
ENSDART00000127203 None None 495 None 12

The following transcripts of ENSDARG00000023920 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 35253232)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 33657341
GRCz11 12 33758324
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGAGGAGCTGGTTGTGGTGGATCTGCAGACTGAAGGGTGGCCCGTCATC[C/T]AGACGCCATACCTGGTGCCATTACACTGTTCAGCCATCACTTGCTCACAC
Long Flanking Sequence:
CATTGTGGACAACAGAACAAACTAGTTCTACAGTTAAGCTAAATTATGAAGCCTTATTTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAGCATCAGAATGAGCCAGAAAGGTGATTTAATGACTTTAAACGTGACATAGTTGTTGGTGCAGACACTAAAGAACCAGTTTGTGGAAATCAATCAGACTTCCCGTTAATATTAGTAAGCGAACTAAAGGAATTATATCCTTTTGACCGAACCAGCTTCAACAATTAGGATTGATTCTTGATTCCCCAGTTTCTCTTAATCTATTATTTCTGGTATCAGTTAATCAGCTTAAACATTTTAGCTGAGCTCCAGTAAGTGCACTTCCTCTAAGTGTGTGTCTGTGTTTCAGGTGAACCCAGCGCTCTTGTGGTTCTTGTGGAGGAGGAGCTGGTTGTGGTGGATCTGCAGACTGAAGGGTGGCCCGTCATC[C/T]AGACGCCATACCTGGTGCCATTACACTGTTCAGCCATCACTTGCTCACACCACGTCTCCTCCATCCCTCTCAAACTGTGGGAGAGAGTGCAAGCTGCGGGAGCCCACCAGAACACACACTACTCCAGGAAGGTATGCATATGTATGACTTAAGCCAGAATTAGCAGGTACATTACAAGCATTTTCCATTTATTATATATAAGTAGGAATAATATACAATACATGTAAAAAAAAATGTACAGGAAACTGAATCTGTTATTTGTCTACAACAATGCAAAATGCTTAACCGTACTATTGTCTTAGAATTCTGTATACACTGTTTGTCCTTCAGGTCCAAAATGACCCATCTTCACTAAACATCCAAAATTAAGCAGCTAAATTTAATTTAAATTCTTAAATCTACTTTGCATAAAGAAAAAACCTTTTTTATCACAAACTCTGTGAATGTGTATTTTTTCCCTTCAGCATTGTGCAGAATTTCAACAATGTTTAATCAGCTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38900
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000034550 Nonsense 403 1020 11 26
ENSDART00000127203 None None 495 None 12

The following transcripts of ENSDARG00000023920 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 12 (position 35253142)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 33657251
GRCz11 12 33758234
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTGCTCACACCACGTCTCCTCCATCCCTCTCAAACTGTGGGAGAGAGTG[C/T]AAGCTGCGGGAGCCCACCAGAACACACACTACTCCAGGAAGGTATGCATA
Long Flanking Sequence:
ATATATATATATATATATATATATATATATATATATATATATAGCATCAGAATGAGCCAGAAAGGTGATTTAATGACTTTAAACGTGACATAGTTGTTGGTGCAGACACTAAAGAACCAGTTTGTGGAAATCAATCAGACTTCCCGTTAATATTAGTAAGCGAACTAAAGGAATTATATCCTTTTGACCGAACCAGCTTCAACAATTAGGATTGATTCTTGATTCCCCAGTTTCTCTTAATCTATTATTTCTGGTATCAGTTAATCAGCTTAAACATTTTAGCTGAGCTCCAGTAAGTGCACTTCCTCTAAGTGTGTGTCTGTGTTTCAGGTGAACCCAGCGCTCTTGTGGTTCTTGTGGAGGAGGAGCTGGTTGTGGTGGATCTGCAGACTGAAGGGTGGCCCGTCATCCAGACGCCATACCTGGTGCCATTACACTGTTCAGCCATCACTTGCTCACACCACGTCTCCTCCATCCCTCTCAAACTGTGGGAGAGAGTG[C/T]AAGCTGCGGGAGCCCACCAGAACACACACTACTCCAGGAAGGTATGCATATGTATGACTTAAGCCAGAATTAGCAGGTACATTACAAGCATTTTCCATTTATTATATATAAGTAGGAATAATATACAATACATGTAAAAAAAAATGTACAGGAAACTGAATCTGTTATTTGTCTACAACAATGCAAAATGCTTAACCGTACTATTGTCTTAGAATTCTGTATACACTGTTTGTCCTTCAGGTCCAAAATGACCCATCTTCACTAAACATCCAAAATTAAGCAGCTAAATTTAATTTAAATTCTTAAATCTACTTTGCATAAAGAAAAAACCTTTTTTATCACAAACTCTGTGAATGTGTATTTTTTCCCTTCAGCATTGTGCAGAATTTCAACAATGTTTAATCAGCTGGCAACATTTGTTTTTGACTAAAGTAAATGATATATTTTTTAATGGTAAAAGTATCTGTACATAAGTTTTTAGCAAAACTGTAATCATAAAA
Associated Phenotype:
Not determined