ZMP
kpna4
Ensembl ID:
ZFIN IDs:
Description:
importin subunit alpha-4 [Source:RefSeq peptide;Acc:NP_958462]
Human Orthologue:
KPNA4
Human Description:
karyopherin alpha 4 (importin alpha 3) [Source:HGNC Symbol;Acc:6397]
Mouse Orthologue:
Kpna4
Mouse Description:
karyopherin (importin) alpha 4 Gene [Source:MGI Symbol;Acc:MGI:1100848]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa32009 | Essential Splice Site | Available for shipment | Available now |
| sa30680 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa32009
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000034456 | Essential Splice Site | 38 | 521 | 2 | 17 |
| ENSDART00000125797 | Essential Splice Site | 38 | 531 | 2 | 19 |
Genomic Location (Zv9):
Chromosome 15 (position 1612524)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 1652409 |
| GRCz11 | 15 | 1617318 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAGACCATGAGAAGACAGCGGACAGAAGTGGTGGTGGAACTCAGAAAGG[T/C]AAGACTGGTTCATGCTTGTAAAATCAGCTGTTTGTGAAAGCACCAAAGAT
Long Flanking Sequence:
AAAAGACAGAAAATGTTACTTTACACACTGTATTGTAAATAAATCTGAAGAGCATTTTCATATTAGTCAATAATATTACTGAAAATAAAAACTGAATAAATGTAAATAAACTCCACGATGGGCTAATAATCAGTGGATTTCTGCAAGCACAGATTCCATGTGGGCCTAGTAATAATAAAATTATATTGATGCTGCATTAGCAATGAGCAGACACCTAGTCCATATCGACTGTCTCAATGCTATTATATGTTTTCTTTATTTAATATGACATTGATTATACAATCTTATTAATCTTGTGCAATAATAATAGGAACTAAAAATACTCCAGTGAATGACCAGCATTCTTCAGAATATTTTCAATTGTTTTTTGGGTGAACTGTCTCTTTAAGAGTGTGAGTGTGTGTGTGTCATGCTGTGATTATCATTAATGATTGTTCTGGTTTCTCCTGTACAGACCATGAGAAGACAGCGGACAGAAGTGGTGGTGGAACTCAGAAAGG[T/C]AAGACTGGTTCATGCTTGTAAAATCAGCTGTTTGTGAAAGCACCAAAGATGAAGAACAAAATCTGACCAAAAAGGAAAGGCTTTTCCTTTTGGGGCTTATGTTGCCAGAACCTAATATTGCATTTTTATTTTCTGTAGAACAAGCGAGACGAGCACCTGCTGAAGCGGAGGAACGTCCCACATGAGGATATCTGTGACGATTCTGACGCAGTTGGAGATTTCAGAAGCGTAAGCAAGTGTTGCGTTACTCGATTAATTGAGGTTTCTAAAGCACTTAAGTGAATTGGGTTTATACTAATTATTGCTTATTGTTTGTAATTATAGCAAAACACTTCTCTTGAGGCGATCGTGCAGGTGAGTCTTGTGTTTTTATTTATGGCATAGAATGCATAAAAATACAATAAAAAAGGAGAATGGTGATTCTCATGAAAACATGTCTGGCTTTTATTTCCCATATAAATCAAAAAAATAGTTTTTATTTTGTTGCCTAATGAAAATTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa30680
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000034456 | Nonsense | 231 | 521 | 9 | 17 |
| ENSDART00000125797 | Nonsense | 231 | 531 | 9 | 19 |
Genomic Location (Zv9):
Chromosome 15 (position 1605391)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 1645276 |
| GRCz11 | 15 | 1610185 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACCTTCCTCCGTAACGTCACCTGGGTCATGGTCAACCTGTGCCGCCAC[A/T]AGGACCCTCCCCCGCCCATGGAGACCATCCAGGAGGTACAAATATGATGC
Long Flanking Sequence:
TATTCAGTGTTAAATGCCCCAATCTGAGTTTAAATACATTTAACGTAACGTTTATTGCCAAACTACTGAAAACAGCAGCTTCTAGTTCACCTCAGATCTTGAAGATTAAATAACTAGCAGACTGTTTGAAAATGAAAGTCAGAACTGAGTGCAAACCAACAAGATTAGTTAATCAGCCCCTGTACTATTCTAATGTTAAATACTTGTTCGATTATAAACCTTACCATTTGGTTGGCAGTGCAGTGACTGGTGTTTAAATCTTCTGTCATGTTTAGTTAGGACTGACAAATTGCCTGTTGCTGGAAGCTTGTCATGTACAGTTATAACACTGATGTTGATGAATGAGAGTACTGTGCTGTTCTGCAGGTGATGGTCCTCAGTGCAGAGATTACGTCATCAGTCTGGGTGTGGTCAAACCACTCCTATCCTTCATCAGCCCCTCCATACCCATCACCTTCCTCCGTAACGTCACCTGGGTCATGGTCAACCTGTGCCGCCAC[A/T]AGGACCCTCCCCCGCCCATGGAGACCATCCAGGAGGTACAAATATGATGCTTATTTTTAAGAGGTGGAAATGGCAGCATTTTAAATGAAATCAAAGCCTCCAAGTTTGTTTTAATTAGAGGGCTCATAATGGTGCTGGAAATCCTTATGTCCTTTCATTTCATTTTTTGCATTTAATGTTTGTTTTTAAATGCCACAGGAATGGAAGTAGGGTTGAAAGCGCTTACATTTGTTGTGCATTTGTCAGTAAAGCTGGCTCTGTAGTCAGCTGTGAATCTCCGGCGCCTGTGTTTACTGCACACAGCCATGGTTGTCTGCCAAACTACACAAAATATCACATGCAACATCATCATGCGATCGTCAAATCGGAAATAATTCTGCGATTAGATCGATATTTGCAGAACTTCTCAATGAACTACGGCCCTTTAAAGTAAACATTGCTCAAGTTAAAGCTGAAAGCACATGCAAATACCACACATAATGGCGTTTTTGCTCAATTCA
Associated Phenotype:
Not determined