Busch Lab

ZMP

ucp1

Ensembl ID:
ENSDARG00000023151
ZFIN ID:
ZDB-GENE-010503-1
Description:
mitochondrial uncoupling protein 3 [Source:RefSeq peptide;Acc:NP_955817]
Human Orthologues:
UCP1, UCP2, UCP3
Human Descriptions:
uncoupling protein 1 (mitochondrial, proton carrier) [Source:HGNC Symbol;Acc:12517]
uncoupling protein 2 (mitochondrial, proton carrier) [Source:HGNC Symbol;Acc:12518]
uncoupling protein 3 (mitochondrial, proton carrier) [Source:HGNC Symbol;Acc:12519]
Mouse Orthologues:
Ucp1, Ucp2, Ucp3
Mouse Descriptions:
uncoupling protein 1 (mitochondrial, proton carrier) Gene [Source:MGI Symbol;Acc:MGI:98894]
uncoupling protein 2 (mitochondrial, proton carrier) Gene [Source:MGI Symbol;Acc:MGI:109354]
uncoupling protein 3 (mitochondrial, proton carrier) Gene [Source:MGI Symbol;Acc:MGI:1099787]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa19606 Essential Splice Site Available for shipment Available now
sa10943 Nonsense Available for shipment Available now
sa18447 Nonsense Available for shipment Available now
sa32779 Nonsense Mutation detected in F1 DNA Not yet available
sa1981 Essential Splice Site F2 line generated Not yet available

Mutation Details

Allele Name:
sa19606
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000038807 Essential Splice Site None 309 None 7

The following transcripts of ENSDARG00000023151 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53870249)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52739820
GRCz11 1 53374558
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCCGGCCCGTCCCGTCCCGTCCCTCCAGCACACACAGATTACTGCCAGG[T/G]CAGAGGATTTTTATTCAGGATCGCACTGCGTTACTAATAATTGGACCGTG
Long Flanking Sequence:
ATAGTCAGAAAGGTAGTAGTTGGCTTTAGGTATGTAAAATAAAGGATGATACTTTATGTGCTAATAAACAGTTCACATCTTATAGTAATAAATCCAGTAATAAATCCGATGCATTGTTACCTAACCTAAAGTGCTACCAGAAATCTTCTTTAGTGACCTGCAGCTTTGAAAACACTCCTCTGCCTGAGTGAATGAGTTTTAATTTATTCCTGTAGTGTGTTGACGAGCGCAGCATCTCGATCAGCTGTGTGTTTTTGTCTTCAGTGTATTATCTAAGCGCTTGTTTATCAGGCTGTTTTGGAGCTGGACTCTGTGCTGAGGGTGGACTTTGTGTGGACCAGTGGTGTGTCCCGCAGAGACGCCTCTTGAATGGAGTCCTGCTTGTGCTCGTATATAAAGAGGGACAGAGAGAGTCCTCGTCCCTCCAGAGCTCCAGGCTTCATCCCTGCCGGCCGGCCCGTCCCGTCCCGTCCCTCCAGCACACACAGATTACTGCCAGG[T/G]CAGAGGATTTTTATTCAGGATCGCACTGCGTTACTAATAATTGGACCGTGTTAGTGTGTGTTTAAGAAAAAAGAAACAATATGCAATATGGTTATTTTGATTGTTTAGTAAATGAGGGTTTTAAATGTGACATTTTAAATATTGTTTCACATTTTGCAAACTCATTTTTTAAATCTTTTTTAATTAAATGTTTAAGTTTTAACATTTAAATGTTTTAAGTTTTTAATTGTTAAATAGATTATGATTTTAAACTTTACATTTTGAAATTAGTTAAAAGAAATTAAAAATGCAAACTTTTGTTAAAAAATGAATTAATTATAAATTAATTATACATTTAAATAATTATATTTTTTTAGGATTTTAAACTGTGATATGTATATATATATATATACACACACACACACACACACACATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10943
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000038807 Nonsense 88 309 3 7

The following transcripts of ENSDARG00000023151 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53874360)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52743931
GRCz11 1 53378669
KASP Assay ID:
2259-1178.1 (used for ordering genotyping assays)
KASP Sequence:
CGGAGGGTCCGCGCTCGCTCWACAACGGCCTGGTCGCCGGCCTACAGAGA[C/T]AGATGGCCTTCGCCTCCATCCGCATTGGCCTCTACGACAACGTCAAGAGC
Long Flanking Sequence:
AGTTGGCGTTTCTGTGTGGAGTTTGCATGTTCTCCCTGTCTTCGTGTGGGTTTCCTCCGGGTGCGCTGGGTTCCCCCACAGTCCAAAGACGTACAGTACAGGTGAATAAATTGTCCGTAGCATATGAGTGTGTGTGTGGATGTTTCCCAGAGATGGGTTGCGGCTGGAAGGGCATCCGCTGTGTAAAAACTTGCTGGATAGGTTGGTGGTTCATTCCGCTGTGGCAACCGCGGTTTAATAAAGGGACTAAGCCGACAAGAAAATGAATGAATGAATATAATCCTGCCCAAAGCAGTCTAACGGTGATCTTTATAAAGTAGTATTCACTAAGCTATCATTTCATGTATTGTTTGTGTGTGTGTTAGATCCAGGGGGAGAAAGCGGTGACAGGAGCCGCTAAAGGCATCCGCTACAAAGGTGTTTTCGGGACCATCAGCACCATGATGAGGACGGAGGGTCCGCGCTCGCTCTACAACGGCCTGGTCGCCGGCCTACAGAGA[C/T]AGATGGCCTTCGCCTCCATCCGCATTGGCCTCTACGACAACGTCAAGAGCTTCTACACGCGTGGAAAAGACAGTCAGTCAAAAAGTCTCCTTCAGCAAACCGAAAGCCTTTTCTTAAAGCTATTTTGTTCATTTCAGAAGAACTTTTTCATTAGATTTAACATTAGGTAACATTCAAAGATTAATCACATGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTTTGTGTGTGTGTGTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATATACAGAGGCTGGACAATGAATGTGAAACTCCTGGTTTTAGGGCTCAGTAATTTATCAGTATGGTGTAGGCAGGGCCTCCTTTTGCGACCAATACAGCATCAGTTCATCTCGGGAGTGACCGAGTGACAGATACAAGTCCTGCACAGTGGCCCGAGAGATTTTAAGCCTTTCTTATTGCAGAATAGTGGCCAGGTCACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18447
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000038807 Nonsense 99 309 3 7

The following transcripts of ENSDARG00000023151 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53874395)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52743966
GRCz11 1 53378704
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCGGCCTACAGAGAYAGATGGCCTTCGCCTCCATCCGCATTGGCCTCTA[C/A]GACAACGTCAAGAGCTTCTAMACGCGTGGAAAAGACAGTCAGTCAAAAAG
Long Flanking Sequence:
CTGTCTTCGTGTGGGTTTCCTCCGGGTGCGCTGGGTTCCCCCACAGTCCAAAGACGTACAGTACAGGTGAATAAATTGTCCGTAGCATATGAGTGTGTGTGTGGATGTTTCCCAGAGATGGGTTGCGGCTGGAAGGGCATCCGCTGTGTAAAAACTTGCTGGATAGGTTGGTGGTTCATTCCGCTGTGGCAACCGCGGTTTAATAAAGGGACTAAGCCGACAAGAAAATGAATGAATGAATATAATCCTGCCCAAAGCAGTCTAACGGTGATCTTTATAAAGTAGTATTCACTAAGCTATCATTTCATGTATTGTTTGTGTGTGTGTTAGATCCAGGGGGAGAAAGCGGTGACAGGAGCCGCTAAAGGCATCCGCTACAAAGGTGTTTTCGGGACCATCAGCACCATGATGAGGACGGAGGGTCCGCGCTCGCTCTACAACGGCCTGGTCGCCGGCCTACAGAGACAGATGGCCTTCGCCTCCATCCGCATTGGCCTCTA[C/A]GACAACGTCAAGAGCTTCTACACGCGTGGAAAAGACAGTCAGTCAAAAAGTCTCCTTCAGCAAACCGAAAGCCTTTTCTTAAAGCTATTTTGTTCATTTCAGAAGAACTTTTTCATTAGATTTAACATTAGGTAACATTCAAAGATTAATCACATGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTTTGTGTGTGTGTGTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATATACAGAGGCTGGACAATGAATGTGAAACTCCTGGTTTTAGGGCTCAGTAATTTATCAGTATGGTGTAGGCAGGGCCTCCTTTTGCGACCAATACAGCATCAGTTCATCTCGGGAGTGACCGAGTGACAGATACAAGTCCTGCACAGTGGCCCGAGAGATTTTAAGCCTTTCTTATTGCAGAATAGTGGCCAGGTCACTACATGGTGCTACAAGTTTCCTGACTCACTCCTCCA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa2013
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000038807 Nonsense 106 309 3 7

The following transcripts of ENSDARG00000023151 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53874416)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52743987
GRCz11 1 53378725
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCTTCGCCTCCATCCGCATTGGCCTCTACGACAACGTCAAGAGCTTCTA[C/A]ACGCGTGGAAAAGACAGTCAGTCAAAAAGTCTCCTTCAGCAAACCGAAAG
Long Flanking Sequence:
CCGGGTGCGCTGGGTTCCCCCACAGTCCAAAGACGTACAGTACAGGTGAATAAATTGTCCGTAGCATATGAGTGTGTGTGTGGATGTTTCCCAGAGATGGGTTGCGGCTGGAAGGGCATCCGCTGTGTAAAAACTTGCTGGATAGGTTGGTGGTTCATTCCGCTGTGGCAACCGCGGTTTAATAAAGGGACTAAGCCGACAAGAAAATGAATGAATGAATATAATCCTGCCCAAAGCAGTCTAACGGTGATCTTTATAAAGTAGTATTCACTAAGCTATCATTTCATGTATTGTTTGTGTGTGTGTTAGATCCAGGGGGAGAAAGCGGTGACAGGAGCCGCTAAAGGCATCCGCTACAAAGGTGTTTTCGGGACCATCAGCACCATGATGAGGACGGAGGGTCCGCGCTCGCTCTACAACGGCCTGGTCGCCGGCCTACAGAGACAGATGGCCTTCGCCTCCATCCGCATTGGCCTCTACGACAACGTCAAGAGCTTCTA[C/A]ACGCGTGGAAAAGACAGTCAGTCAAAAAGTCTCCTTCAGCAAACCGAAAGCCTTTTCTTAAAGCTATTTTGTTCATTTCAGAAGAACTTTTTCATTAGATTTAACATTAGGTAACATTCAAAGATTAATCACATGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTTTGTGTGTGTGTGTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATATACAGAGGCTGGACAATGAATGTGAAACTCCTGGTTTTAGGGCTCAGTAATTTATCAGTATGGTGTAGGCAGGGCCTCCTTTTGCGACCAATACAGCATCAGTTCATCTCGGGAGTGACCGAGTGACAGATACAAGTCCTGCACAGTGGCCCGAGAGATTTTAAGCCTTTCTTATTGCAGAATAGTGGCCAGGTCACTACATGGTGCTACAAGTTTCCTGACTCACTCCTCCAAAACACCTCAAAGTGGCTTAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32779
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000038807 Nonsense 154 309 4 7

The following transcripts of ENSDARG00000023151 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53875841)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52745412
GRCz11 1 53380150
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGTGGTAAAGGTGCGTTTCCAGGCCCAAATGAACCTCCAGGGTGTGGGC[A/T]GACGATACAACGGCACCATGCAGGCCTACAGGCAGATCTTCCAGCTTGAG
Long Flanking Sequence:
GTGACCAAAGGTTTGGCTATAGCAGCCCGGCCATGTATACTGACTCTTTGAAGTCATTGGAAATTTAGTCATGAAACCTCCATCCCTAAATTGGCCAGTGTTTCAGTTTCATCCTCCAACCCTTATACAGATTTTATCTAAAAGTATTTTCTCAATTATATACATGCATGTGTGTATTATATATCTAATAAATATACACAGTGCACACACATTATGTCAAAACACATTTTTTGGCCAGCCATAATTAATAGTGAAATAAACAATAAAATTTTCTTAATTATTTACTGCAATCTGTGACCCTGAATCACAAAATGCACATGTATGAATGTAAAAAAAAAAAGCTCATATCTGTCTTGTCCTGATGTTTCTCTGCAGACCCTAATGTGGCGGTGCGAATCCTGGCGGGCTGTACTACCGGAGCGATGGCCGTGTCCATGGCTCAGCCCACAGACGTGGTAAAGGTGCGTTTCCAGGCCCAAATGAACCTCCAGGGTGTGGGC[A/T]GACGATACAACGGCACCATGCAGGCCTACAGGCAGATCTTCCAGCTTGAGGGACTCCGTGGTCTCTGGAAAGGTACAGGCAGACGTACTGAATCTATGGGGTCATTTACTTGTACACTACATAGGGAGCGAGTGATCAGTGACTCAAAGAATATTCCAAAAGTTTGCAAGTAAAATGATGTACAGAAAAATCCACCAATCAGAGAGTCACATTCTGCAATGGATGCTGAAATATGCAAATTTAACAAAAATGTCAAATATGTTGATTCTGTAGTTGATTATGAAATTATTTTTGTATTATTATAGAATATTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATAAAAAAAAAATACATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAGTTGAAGTCACAATTATTAGCCCCATTTATTTTTTCCCCAATTTCTGTTTGATGTTGAGCAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1981
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000038807 Essential Splice Site 212 309 6 7

The following transcripts of ENSDARG00000023151 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53880657)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52750228
GRCz11 1 53384966
KASP Assay ID:
554-2777.1 (used for ordering genotyping assays)
KASP Sequence:
TATCCCTATAACCGATTGCAATAGTAATGTATTGTCCCGTTTCTGCATGC[A/T]GACAATCTCCCGTGTCACTTTGTGTCTGCGTTCGGCGCGGGCTTCATCAC
Long Flanking Sequence:
TATTCCGCTGTCTCCAGAAACGTCCGCGGGACTACGTTTTCAGAATGAGCTTGGGTTGAATCAAACACACCTGAAGCAGCTAATCAAGCTCTTACTAGATGTACTAGAAACTTCCTGGCAGGTGTGTTGAAGCAAGTTGGAACTAAACTCAGCAGGACACCGGCCCTCCAGGACCAAGTTTGGACACCCCTGGACTAAGCCAAAGGAATATGAATGAATGTTAAGTTATTATAAATAAACATGAAGAACCTGCAGTTATATAGCCTATAGGTGATGTCTATGTGTCCATATTCAATGAAGAGTATTAAGTGTTTGTGTTGTCCTTTAAGTCTTCCATGGTTGGCAGAATTAGTTTTTCCTACTATGGAAGGAAATGGTTGCAGGTTTTGTTGTACAGAATAAAGAAACTCAGAGATTTATAACTTGAGGGAGAGCAATAAATAGCTGAACTATCCCTATAACCGATTGCAATAGTAATGTATTGTCCCGTTTCTGCATGC[A/T]GACAATCTCCCGTGTCACTTTGTGTCTGCGTTCGGCGCGGGCTTCATCACGACGGTGATCGCGTCTCCTGTGGATGTGGTAAAAACACGGTACATGAACTCTCCACCGGGACAGTACAGCAGCTCCACCAACTGCGCCTGGACCATGCTCACTAAAGAGGGACCCACAGCTTTCTACAAAGGGTGAGCGAGCATTTACACCAACTATAATTACTCGACTCATTTTCTTGTTGTGATTAATTGCTGAAGCTTTCATCGCGATATTGAGACAAGCTCCAGAGACTGTAGCCCCTTCTGTATATACAGTTGAACTCAGAATTATTAGCCCCCCTGTATTTTTCACCCCCCTGTATATTTTTTTCCTAATTTCTGTTTAACAGAGAGAAGATTTTTATCAACACGTTTCTAATCAATATAGTAATAACACAAAAAAATGTACTGTATTACTGTATAGTGTACAGTTAAAATCAAAATTATTAAACTATTAGTTCTGTTTTTATT
Associated Phenotype:
Not determined