ZMP
abcb5
Ensembl ID:
ZFIN ID:
Description:
Im:7158730 protein [Source:UniProtKB/TrEMBL;Acc:A9JR76]
Human Orthologues:
ABCB1, ABCB4, ABCB5
Human Descriptions:
ATP-binding cassette, sub-family B (MDR/TAP), member 1 [Source:HGNC Symbol;Acc:40]
ATP-binding cassette, sub-family B (MDR/TAP), member 4 [Source:HGNC Symbol;Acc:45]
ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:HGNC Symbol;Acc:46]
ATP-binding cassette, sub-family B (MDR/TAP), member 4 [Source:HGNC Symbol;Acc:45]
ATP-binding cassette, sub-family B (MDR/TAP), member 5 [Source:HGNC Symbol;Acc:46]
Mouse Orthologues:
Abcb1a, Abcb1b, Abcb4, Abcb5
Mouse Descriptions:
ATP-binding cassette, sub-family B (MDR/TAP), member 1A Gene [Source:MGI Symbol;Acc:MGI:97570]
ATP-binding cassette, sub-family B (MDR/TAP), member 1B Gene [Source:MGI Symbol;Acc:MGI:97568]
ATP-binding cassette, sub-family B (MDR/TAP), member 4 Gene [Source:MGI Symbol;Acc:MGI:97569]
ATP-binding cassette, sub-family B (MDR/TAP), member 5 Gene [Source:MGI Symbol;Acc:MGI:1924956]
ATP-binding cassette, sub-family B (MDR/TAP), member 1B Gene [Source:MGI Symbol;Acc:MGI:97568]
ATP-binding cassette, sub-family B (MDR/TAP), member 4 Gene [Source:MGI Symbol;Acc:MGI:97569]
ATP-binding cassette, sub-family B (MDR/TAP), member 5 Gene [Source:MGI Symbol;Acc:MGI:1924956]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa2844 | Essential Splice Site | F2 line generated | Not yet available |
| sa42702 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa8683 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa2844
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079185 | Essential Splice Site | 51 | 601 | 3 | 15 |
| ENSDART00000141616 | Essential Splice Site | 51 | 1338 | 3 | 29 |
Genomic Location (Zv9):
Chromosome 16 (position 21523985)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 19760860 |
| GRCz11 | 16 | 19566679 |
KASP Assay ID:
554-2671.1 (used for ordering genotyping assays)
KASP Sequence:
CTCATGAAGACAAACCAGAGGAGCCACCCAGTGACTCAAAGCACAAAGGG[T/C]ACATACTGATTGAGCAGCAAGTGGATTGTTTTATTMATGTAGAGAGAATT
Long Flanking Sequence:
TAGCAACAAGAATACTGTGTTTTCACAATGAAAGACGGACCACCTGAAGAATCAACAGACCCCCCACCCTACTCGCATGGTAGTTTCGCATTTTACATTTATGCATTTGGCTGACACCTTCTCCAAATCAATTTTCACATGTTAAATCAACTAACAACCAACATGGTGCAGATTGGCAAGCCTAGAAACTCAATTATTCTACTATAGACTAGCACTCATGATTAAAGTATGTGTGATATTGAAAAATGCTGAAATATTTTTTTTCATTCATTCATTTTCCTTCAGCTTAGTCTTTGTTTCAGAGGTCACTAAATTATTTTACATAAATTATTTTGATCATGAAGACACCTTAGACTTTTAGCGCATGCTCTTTAATAAACAAGCTCTTTCTTTTCTCAGAGGCGATCCCTGAGGGCTTTGTAAACCTCGCTTACAGCCAAGATGAGAAACCTCATGAAGACAAACCAGAGGAGCCACCCAGTGACTCAAAGCACAAAGGG[T/C]ACATACTGATTGAGCAGCAAGTGGATTGTTTTATTCATGTAGAGAGAATTAAGAAATGTGTCTGCATTTTATAAATGATGGGTGGTTTCTGAGTAAAATATGGACAAACCCAAATGTAGGGTTAAAAGTAGGTCATTTAAGAAAACAGCAGTTGGGTTTGTCTTATTTAAATCAGCATTTTTAGAATATATAAGCCAGTGACAGAAAATAAGCAGGGCTTGAGGCAAAAATTCCATGGAAAGTTGCCTCACTCCCTCAATTCAAAATCAATAACATTCATTTGTATTTAGTTAAATAGTACAAAAAAAAAAAAAAAAAAATATATATATATATATATATATATATATATATACATACATACATACATACATACATACACACACACACACACACACACACACACACACACACACACACACACACACACACATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42702
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079185 | Essential Splice Site | 123 | 601 | 6 | 15 |
| ENSDART00000141616 | Essential Splice Site | 123 | 1338 | 6 | 29 |
Genomic Location (Zv9):
Chromosome 16 (position 21522147)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 19759022 |
| GRCz11 | 16 | 19564841 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAAAGATCTGGTAGGACTGGTTTCAAAACATCTTTCTTTCAAATGTTTGC[A/T]GGCTTCAATGGGAACTTCACCTCTAACTTCACCTTCACCCTCAACAACAC
Long Flanking Sequence:
TGACAGCTTTGTGCAGAGTGGGCAGACGTACAATCTGACAGGTATATTAATTGTTGAAACACTGTAAGATTTGATAAATAAAGAAGCATCCTTACAAGCAAATGCATGAACATCTAATATCTCCTTAAAGGTCCAGTTTAGCTAAAAATGAAAATTGTCACATTTTACTCACTTGTTCCAAACCTGTTTGAATTGCTACCTTCTGTTGAATAGAATAGAAGATATTTTGAAGAATGTTTGTGACTTCCATAGTATATTCCCCTACTATTGTAGTCAATAGCGGTTTCCAACACTGTTCAAAATATCTTGAGGTTGAGTGAATTGTCATGTTTGACTGAACGATCTCTTTAAGACCTAAAGTCAACAAAGCAGCCTGTTTTGAGTTGGTACAGTAGTTTAAACTTAGCCCTAAGTGTCACAGTTCAGCAGTCCTTTCATAAATATTTAATGTAAAGATCTGGTAGGACTGGTTTCAAAACATCTTTCTTTCAAATGTTTGC[A/T]GGCTTCAATGGGAACTTCACCTCTAACTTCACCTTCACCCTCAACAACACTTCAACGTGTTTGGCTGGTTCTCCGGAAATAGGCATTGAACCTAAAATGACAAAGTAAGGATCAGTCTGGTGTCACATTCATGCTCTGAATAATTCAGTGCAGCATCTTAGTTAACGTCAGTGATCAGGGGTATAAAATACTTAAATCCTTTTAATTTTATCCTCCTACCCAAGTATTGTTTTTAGTGAATTAAAACTACAAAAAAAGGCCATGTCATGATGAAAATCCGGTGTGCTCGAAACTTTACACATTGTTGTATCCTTTTATAAATAAAAATAAATGTGATATTTCTGGAGCTTAGGTGTTGCCACATTTTCATTTTTTTTTTTTTTTGTACTTTTTGTTTGACTGCGCACCCATTTTAGATTTATATACATGCTTTTTTGTGAATATTTTAGCAAATTAAAAGTAACTTTGTACGTGTGTGCATCACATAACAAGAAACTGCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa8683
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000079185 | Essential Splice Site | 417 | 601 | 11 | 15 |
| ENSDART00000141616 | Essential Splice Site | 417 | 1338 | 11 | 29 |
Genomic Location (Zv9):
Chromosome 16 (position 21517106)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 19753981 |
| GRCz11 | 16 | 19559800 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCCAAGGCCCGGGGTGCTGCTTATGAGRTCTACAARACTATTGACATGG[T/C]AAAAACTTTAAGTCTTTTACAGTAAAGGTCATTTTTTATTATATTTATAG
Long Flanking Sequence:
CTTTATTAAGACTTCAATACACTACAGTCATAGTGGATGAGTGTTTGTGTGATTGTGTGTTTGGGTGTTTCCCAGTACTTTGTTGTAGCTGGAAGGGCATCTGTTGTGTAAAACATATGTTGGAATAGTTATTCTTGAGAACCCCAGAGTACCAACCCCTGATAAATAAGGGACTAAGCCTAAGGAAAATGAATGATATGTTTGGAAATGTAAACTGATAATTCCTTTAGACATATTAGCGTGAATGATAGAAGTAACCGACTTTATTAAATTTATTTATTTTAATTTATTTGTATTTTGTTTGTGAAAACACTAATGGCCTAAGATGTGTGTAAAGTACTAGAAGTCATTTTTTAACCAGCATCTTTGTATTGTTTGACCTCAGGTTTTCTTCTCTGTTATGATTGGCACTTTCTCTTTGGGTCAAGGAGCTCCAAACCTGGAGGCCATTGCCAAGGCCCGGGGTGCTGCTTATGAGGTCTACAAAACTATTGACATGG[T/C]AAAAACTTTAAGTCTTTTACAGTAAAGGTCATTTTTTATTATATTTATAGCCATAATGTCACATTGGATGACTTATTGTTTTTCTATACCTGCTGCAGCCTCGTCCCATTGACAGCAGTTCAAAAGAAGGACACAAACCAGACCGTGTGAGAGGAGATATCGAATTCAAAAACATTAATTTCAATTACCCCTCCAGAAAAGATGTGACGGTGTGTTTTGCAATATTTTTTTATAAAGATGTAATTTATTTATTTTTAAATATTAATATAATTAATTTTATGTATATCTGTATTATATTTATAATTCTGAATATGTTCAAACATGCGTACATTTATTAAACAAACAGTAAATGCAATATGTACACACGCACAAACCAAGAAAACATTTTCATTTAGTGTACTATGATTTAGAATAACTAAAACAAAATAACACTCGATAAAAATCGTAATTTAAAATGAAAAGCATACATGTATGTTAATGTTAATAAATATTGTTAAAAA
Associated Phenotype:
Not determined