Busch Lab

ZMP

tmem178

Ensembl ID:
ENSDARG00000020758
ZFIN ID:
ZDB-GENE-060929-756
Description:
Transmembrane protein 178 [Source:UniProtKB/Swiss-Prot;Acc:Q08CE6]
Human Orthologue:
TMEM178
Human Description:
transmembrane protein 178 [Source:HGNC Symbol;Acc:28517]
Mouse Orthologue:
Tmem178
Mouse Description:
transmembrane protein 178 Gene [Source:MGI Symbol;Acc:MGI:1915277]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa41870 Nonsense Mutation detected in F1 DNA Not yet available
sa9980 Nonsense Available for shipment Available now
sa1210 Nonsense F2 line generated Not yet available
sa27806 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa41870
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008594 Nonsense 91 301 1 4
Genomic Location (Zv9):
Chromosome 11 (position 31389823)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 30267185
GRCz11 11 30514369
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTGGCGCTCATGAAGCCCATTCACGTTGGGAGTCGAGAGGAGGAACTGT[T/A]GGAGAACTGGAGGGCGATTTTGGGCATGGGCATTTTGGAGACGGAGTGCG
Long Flanking Sequence:
GCGGCTAAAAGAAGATGCACAGACGCCGAAGGCAGTGCAGGTAAACACGCACGCACGGCCATCGCGCATCCCCATATAGATGCCCACGGCACCGCACGCGCAGACACACTCCGCTCATCCACCTGTAATGACAGATCGCTGCCCAAAGCGGTGCATTGTCCCAGGAAACGGCGAGGAAAGTCCGCTTCGCGTGAGAGATGACTGAGTGAGTTGCGCGGATGTTGGAGACATGGAGAAACGGGCTCTTGTAACGGCGATCAGCTTGTCCATGAGCCTGCTCGCGCTCATGCTGCTGGTCACTGCGATCTTCACCGATCACTGGTACGAGACCGACACCAGGAGACACAAGGAGAACTGCGACCAGTACGGGTCCGAGTCCAACGACCAGAAGAACAGGGAGATGCCCATCTATCACCTGCCTCTGGTGGACAGCGGGAACGCGAAGCGCAACCTGGCGCTCATGAAGCCCATTCACGTTGGGAGTCGAGAGGAGGAACTGT[T/A]GGAGAACTGGAGGGCGATTTTGGGCATGGGCATTTTGGAGACGGAGTGCGGGCGCCCGCTTTTCTCCACCTATTCGGGACTATGGAGGAAATGCTACTTCCAGGGAATGGACAGGGATATTGACAAACTCATTTTGAAGGGTAAGGCTTAGGTGGAAAGTTCATTTCGATGCAAAATATACAGAGGAAAAAATGTGTGCTTAGTTGGGTGTGAAGCGGTTTAGTGCCAGCCAACAGAACTAAACGAAGTTCGAGACTTTTCTTTTTTCTACTACCCTAACACAAAAGAGTTCCCTGCGCTAAATCTAACGCACGTCCGAATGTCAAACAAATAATTCTCATGAGTCGACTCTAACAGCATTCAGCGCAACCAGAGTAGTTCCATTAGTTCCAAACGAATGATTGTAATGAGCTGGCTATGTAATAGTTGTTTTTGATGAATCAACACACCTACAGTAGCTATTAACCAATCAATAAATAAGACAGACAGGTTTTAACCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9980
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008594 Nonsense 116 301 1 4
Genomic Location (Zv9):
Chromosome 11 (position 31389898)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 30267260
GRCz11 11 30514444
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATGGGYATTTTGGAGACGGAGTGCGGGCGCCCGCTTTTCTCCACCTAYT[C/A]GGGACTATGGAGGAAATGCTACTTCCAGGGAATGGACAGGGATATTGACA
Long Flanking Sequence:
ATAGATGCCCACGGCACCGCACGCGCAGACACACTCCGCTCATCCACCTGTAATGACAGATCGCTGCCCAAAGCGGTGCATTGTCCCAGGAAACGGCGAGGAAAGTCCGCTTCGCGTGAGAGATGACTGAGTGAGTTGCGCGGATGTTGGAGACATGGAGAAACGGGCTCTTGTAACGGCGATCAGCTTGTCCATGAGCCTGCTCGCGCTCATGCTGCTGGTCACTGCGATCTTCACCGATCACTGGTACGAGACCGACACCAGGAGACACAAGGAGAACTGCGACCAGTACGGGTCCGAGTCCAACGACCAGAAGAACAGGGAGATGCCCATCTATCACCTGCCTCTGGTGGACAGCGGGAACGCGAAGCGCAACCTGGCGCTCATGAAGCCCATTCACGTTGGGAGTCGAGAGGAGGAACTGTTGGAGAACTGGAGGGCGATTTTGGGCATGGGCATTTTGGAGACGGAGTGCGGGCGCCCGCTTTTCTCCACCTATT[C/A]GGGACTATGGAGGAAATGCTACTTCCAGGGAATGGACAGGGATATTGACAAACTCATTTTGAAGGGTAAGGCTTAGGTGGAAAGTTCATTTCGATGCAAAATATACAGAGGAAAAAATGTGTGCTTAGTTGGGTGTGAAGCGGTTTAGTGCCAGCCAACAGAACTAAACGAAGTTCGAGACTTTTCTTTTTTCTACTACCCTAACACAAAAGAGTTCCCTGCGCTAAATCTAACGCACGTCCGAATGTCAAACAAATAATTCTCATGAGTCGACTCTAACAGCATTCAGCGCAACCAGAGTAGTTCCATTAGTTCCAAACGAATGATTGTAATGAGCTGGCTATGTAATAGTTGTTTTTGATGAATCAACACACCTACAGTAGCTATTAACCAATCAATAAATAAGACAGACAGGTTTTAACCTAAGGGTGTTGGGCAGGGGGTGGATCTGAGTAACAGGGGCCTTGGAGAGAGAGAGTGGGGGTCAGCATAATGATACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1210
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008594 Nonsense 155 301 2 4
Genomic Location (Zv9):
Chromosome 11 (position 31395491)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 30272853
GRCz11 11 30520037
KASP Assay ID:
554-1119.1 (used for ordering genotyping assays)
KASP Sequence:
GTATTGCAGAGCGATGCACATCTGTCAAGTACCATTTCTCCCAACCCATC[A/T]GACTCAGGAACATCCCTCTCAACCTGACGAGGACCATACAGCAGGACGAG
Long Flanking Sequence:
GTTCAGAAAGGGTACATTTTAATTTCACCCACACATTTCGGATCCAGCCAGCTTGAATTCATGTCTCTGACTGAATGAATTGACCGTATCCCCCCACACTATGAGTCCAGAACGTGTTTTAAAATATTATTAATTACCTAATGCTTGCTGCATGATCACTGCAGTCTCATTCCAGCTCGCAGAATTAGCTCCCAACGCCGGCCAAATCTGTGTGGTGTTGGTGTGAACTCAGGCGGAAATAATGACAGAAGGTCACTCTGTCGGGGAGGCTGGAGTTTCAGCAAAGCTTGAAACGTCTAGGGAAAAGACAAACAATAAAACAAAGAGTCGAGAAGATTAGTGCAAACAGAAAATGCAATATACCAGCAGCGTGTCGTTTTATTTGTGTGGGATTTCAGCTTGGTTTGAAGGTGGGAGTTTGTCCTAAATGAGTGTGCGATCTGTGCGCAGGTATTGCAGAGCGATGCACATCTGTCAAGTACCATTTCTCCCAACCCATC[A/T]GACTCAGGAACATCCCTCTCAACCTGACGAGGACCATACAGCAGGACGAGTGGCACCTCTTACGTAAGTTGCCCAAAGCTTCCTCACCACCGCCTTGTGCAGCTCTTGATATGCCATGAATATTAAGCAGAGCTCGCAAGCTGGAGTTAAGTGTGCTTTGCATGGAGAAAACTGCAGAGAAAATCCTTGTAAAATAAAACCTAAAGGCTGATGCTTTTCTGCTTAGTTTGATTTTGATCAATGCTGTTCAGTTTCTTAAAAGGATAGTTCACCCCAAAATTTAAATTCTGCCATTGTATATTAAATGTATGATAATTTACTCACTATTTGCTCTCCCTCAAGCGGTTCCCAACCTTTATGATTTTTCTTTCTTCTGTTGAACACAAAAGAAAATATTTCAAAGAAAGTTGGAAACCTGTAACCATTGACTTCCATAGTATCTGTTTTTTTTCTACTATGGATGTCAATGGTTACAGGTTTTCAGCTTTCTTCAAAATATC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa27806
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008594 Essential Splice Site 176 301 3 4
Genomic Location (Zv9):
Chromosome 11 (position 31401635)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 30278997
GRCz11 11 30526181
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAGATAAGGTGTGAGTTGGCTAAGTGGGCGATATGTGTGTGTGTGTTTC[A/T]GATCTGCGGCGCATCACGGCAGGGTTTTTGGGCATGGCAGCAGCCGTAAT
Long Flanking Sequence:
AATGGATTTGCTCTTCAATGTTTAGACTTTCAGCAGTGAAATTAAACCACACTGAACTGAACTAAACTGAACGTCAACTCTGAAAACTGGACTGACACAGTTTCAATTTACTAGAACTTCTATGCTAAGCTGCTTTGACACCATTTACATTGTAAAAGTGCTATAGAAATAAAGATGAATTGAATTATTATTATGTTTGCACAAGATTTTATTAAGTGAATGAAATATATAACCACTAAATAGAAATGTTCACAAAATCTAAACAATAAAAGAAATTTGAATAAAAATGATATTAAAAATACACCTTTGCATCAAAATGTTTCATTTGGAGTTCATGGCAAAATATGGAGAATAGAGCCTCATAAAGCTTTGGAATCACCAGATGATAACGAAATGTTCATTTTTGGGTGAACTATCCCTTGAAATCCTCACATTTCAGTGAAAGTTCCTAAAGATAAGGTGTGAGTTGGCTAAGTGGGCGATATGTGTGTGTGTGTTTC[A/T]GATCTGCGGCGCATCACGGCAGGGTTTTTGGGCATGGCAGCAGCCGTAATGCTGTGTGGAAGCATCGTGGCCGCGGTTGGATTTTTCTGGGAGGAGAGCCTCACTCAGCATGTGTCTGGACTCCTGTTCCTTATGGCAGGTACATCATTCTGTTCATTCGCTCTTCCTTGGATCTTCTTTTTTCATACTCAGCTACTTGTTACTCGTTTCTCCCAGTCGCAGTGTTTCTTGTAGGTGGTTCTTTTTCCTTTCCAAGTTGTTGTCTACCTTGTTCATTCTCCCACGTCTTGTATATTCATCTGTTTTTCTCCTTCTGTCTCATTTGTCTTGGACTTATACAGTACTGTACATATGTACACACATTACACACACACACACGTCCCCACCGGGAAATAAAAACAAGTACACATACACACACATATACTTCTGGTTTATGAGGACTATCCATAAATATATTATGTTTTATACAGTAGAAAACAAGTACACATTCACACACACAC
Associated Phenotype:
Not determined