Busch Lab

ZMP

tmtc4

Ensembl ID:
ENSDARG00000020447
ZFIN ID:
ZDB-GENE-070912-148
Description:
transmembrane and tetratricopeptide repeat containing 4 [Source:RefSeq peptide;Acc:NP_001166973]
Human Orthologue:
TMTC4
Human Description:
transmembrane and tetratricopeptide repeat containing 4 [Source:HGNC Symbol;Acc:25904]
Mouse Orthologue:
Tmtc4
Mouse Description:
transmembrane and tetratricopeptide repeat containing 4 Gene [Source:MGI Symbol;Acc:MGI:1921050]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa14987 Nonsense Available for shipment Available now
sa21512 Nonsense Available for shipment Available now
sa34677 Nonsense Mutation detected in F1 DNA Not yet available
sa21511 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa14987
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078681 Nonsense 285 739 7 17
ENSDART00000127214 Nonsense 285 739 8 18
ENSDART00000133427 None None 62 None 4
ENSDART00000136838 None None 55 None 3
ENSDART00000142904 Nonsense 285 299 8 8
ENSDART00000146268 None None 32 None 2
Genomic Location (Zv9):
Chromosome 9 (position 32549326)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 31705272
GRCz11 9 31516018
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGGTTGRCTCTACTCTTTCTTGGTGGTTCCTTACTTATGTACAYGAGATG[G/A]AAAATCATGGGAACTGGACCTCCATCTTTYACMGAGGTGGATAACCCAGC
Long Flanking Sequence:
CAGTTGGTGGCGATAAAAAGTTCTCTGTGTTGTGGATATTTGGCAGCATTCTTCTGTGTGCTGTAGCCATGCTCTGCAAGGAACAAGGCATTACGGCTTTGGTAAGTGAAAATATGTATACAGGTCAAATACAGTAATATAAACACACACAGCATATGCCGTACCTCACATCTGTTTTTAAACTAGCTCCTTCACCATCCATAAAATATCCTTGTTCTTTTTTTTTTTTTTTTGTCTGAAGGGAGTTAATGCTGCTTATGACATTCTCATGGTGTGCAATCTGAACATTTATGAGCTTGCTCACCGGCTGCTGTCCAGGAGAAAATCAGCTGACGTAAGTGTCGGATTCACAGGATGTCACTCTTTATACCCAAACAATCTCTCTAATGGATTTAAACTTTTCTCTTTTGCACCCAGATTGGTGGCTTGCCAAGAAACGGTTTGCTTATGAGGTTGGCTCTACTCTTTCTTGGTGGTTCCTTACTTATGTACACGAGATG[G/A]AAAATCATGGGAACTGGACCTCCATCTTTCACCGAGGTGGATAACCCAGCATCCTTTGCAGAAAATATCATCCTGAGGGTAAGCAGTCCTTTCAGTTTGACAGTTAAAAGTCTACGTAGGGAAAAATGACTTGTTTTTGTAAAGTATGCTTTTAGTAAATTTAAAACAATTATTATTATCATTATTTTCTTAAATTATATTTGTTTTGCTCTAGTTTCAAAGTTAAAAAACAGAAGTCTTACTTGTTGGTATTGAGCGCTTATATATTGGTGTTGTGGTAAACCTAATAAAACTCAATACTTTAAGGGGGAAATGAAGCACTCAGTCAAGTTTGCATTCTTTTGTGCATTGTATTTCACTTTAATAAAAATATATTAAACAAACTTGATTAATGTAACCATTTAGCTGAAAACGGCCTGTTTTACTATAGCTTTTAGACCTAGGGCGCCACCAACTTGGAATGTCGATGTGTCTGACGTCACAGGGTTGGTTTCGTTCCG
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa2500
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078681 Nonsense 324 739 8 17
ENSDART00000127214 Nonsense 324 739 9 18
ENSDART00000133427 None None 62 None 4
ENSDART00000136838 None None 55 None 3
ENSDART00000142904 None None 299 None 8
ENSDART00000146268 None None 32 None 2
Genomic Location (Zv9):
Chromosome 9 (position 32545877)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 31701823
GRCz11 9 31512569
KASP Assay ID:
554-2971.1 (used for ordering genotyping assays)
KASP Sequence:
RTCTTTTCTCAGATTGTGAACTATAATTACTACTACTCTTTGAATGCCTG[G/A]TTGCTGCTGTGTCCCTGGTGGCTGTGTTTTGATTGGTCAATGGGCTGTGT
Long Flanking Sequence:
TGACCTTATGAACCCTGTATTAGACACACTTTTAATGCTTGTATTTGCATCAGCTCCACGCCCACCACTCTACGCATTGGGTTAAATCAGGCTTTGCGGTGTGTTTAGTCCATTACTTTCACTGTATCTGTTTAGCTGAGGGAACAGAACCAACCCTGTGACATCAGGTACAGCAATATTGCAAGATGGAGGCGCCCTAAGTCTAAAATCTATAGTAAAACATGTTGTTTTCTGCTAAATGTTTATTTATTTATCGACTTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAATGTCCATTTAAGTGGAAATTATTTACAAAACAATGTAAACTTGACTGAGTGCTTCATTTACCCTTTTATAAAAGTGTTGTGGTTACACAGACTGTCATATAGTATATTCTCTGTCATCTTTTCTCAGATTGTGAACTATAATTACTACTACTCTTTGAATGCCTG[G/A]TTGCTGCTGTGTCCCTGGTGGCTGTGTTTTGATTGGTCAATGGGCTGTGTGCCTCTGATTAGCTCAGCTGCTGATTGGAGGATCGTCTGGCCTGCTGTGCTGTGGTTCTGTCTGATTGGCTTGGTGAGCCAAGCTCTGTTCTCACAGGACAGTAATAAAAGAAGGTAAGCACTGTATCAAAATACGACATGCTGTGAGTAGACTTTTGGAAATGGAGACGTTATCTTAAGAAGACAGTCTGATTGTTGTTATCTGAACATTTGTTTCTACACAATTATACTGTCTGTCTATCATACTGCAATACTGCTGTAAGGCAGTCTGGGTTATTCTGCATTTACTGGATTTATTGGGTATGGATTTAAGTAATGTTAATGTCCTTTATTTTATTTTAATATGGTCCAAATTTCAATTAAAATATATATTTTGATCATTTTAGGTTTTCTTTTCCCGGAAATAGCAGTTGGTCAGAATAATAAATAACAATACTACTAATTATAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21512
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078681 Nonsense 359 739 8 17
ENSDART00000127214 Nonsense 359 739 9 18
ENSDART00000133427 None None 62 None 4
ENSDART00000136838 None None 55 None 3
ENSDART00000142904 None None 299 None 8
ENSDART00000146268 None None 32 None 2
Genomic Location (Zv9):
Chromosome 9 (position 32545772)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 31701718
GRCz11 9 31512464
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGATTAGCTCAGCTGCTGATTGGAGGATCGTCTGGCCTGCTGTGCTGTG[G/A]TTCTGTCTGATTGGCTTGGTGAGCCAAGCTCTGTTCTCACAGGACAGTAA
Long Flanking Sequence:
TAGTCCATTACTTTCACTGTATCTGTTTAGCTGAGGGAACAGAACCAACCCTGTGACATCAGGTACAGCAATATTGCAAGATGGAGGCGCCCTAAGTCTAAAATCTATAGTAAAACATGTTGTTTTCTGCTAAATGTTTATTTATTTATCGACTTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAATGTCCATTTAAGTGGAAATTATTTACAAAACAATGTAAACTTGACTGAGTGCTTCATTTACCCTTTTATAAAAGTGTTGTGGTTACACAGACTGTCATATAGTATATTCTCTGTCATCTTTTCTCAGATTGTGAACTATAATTACTACTACTCTTTGAATGCCTGGTTGCTGCTGTGTCCCTGGTGGCTGTGTTTTGATTGGTCAATGGGCTGTGTGCCTCTGATTAGCTCAGCTGCTGATTGGAGGATCGTCTGGCCTGCTGTGCTGTG[G/A]TTCTGTCTGATTGGCTTGGTGAGCCAAGCTCTGTTCTCACAGGACAGTAATAAAAGAAGGTAAGCACTGTATCAAAATACGACATGCTGTGAGTAGACTTTTGGAAATGGAGACGTTATCTTAAGAAGACAGTCTGATTGTTGTTATCTGAACATTTGTTTCTACACAATTATACTGTCTGTCTATCATACTGCAATACTGCTGTAAGGCAGTCTGGGTTATTCTGCATTTACTGGATTTATTGGGTATGGATTTAAGTAATGTTAATGTCCTTTATTTTATTTTAATATGGTCCAAATTTCAATTAAAATATATATTTTGATCATTTTAGGTTTTCTTTTCCCGGAAATAGCAGTTGGTCAGAATAATAAATAACAATACTACTAATTATAATGTAAAAATAAGTGTTTTTCTACCACTGATGCGACTATATTTTTAATTTCATATGATTCCTTATACAGCATTGATACAATATAATCTGTTAAGTAGACTTAAGCATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34677
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078681 Nonsense 466 739 10 17
ENSDART00000127214 Nonsense 466 739 11 18
ENSDART00000133427 None None 62 None 4
ENSDART00000136838 None None 55 None 3
ENSDART00000142904 None None 299 None 8
ENSDART00000146268 None None 32 None 2
Genomic Location (Zv9):
Chromosome 9 (position 32543654)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 31699600
GRCz11 9 31510346
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTGAATGTGACTCGCTCTGCACAGCGCAGTCAACAGTGGAGGTCTGAA[C/T]AGAGTCTCTTCACCAGCGCCCTTTCTGTGTGCCCGCTCAACGCCAAGGTG
Long Flanking Sequence:
GTATTTGAAATAAATAAAAAACTAATTAGTAATAATAATCAGTATTGTAATAGTATTTAATTCCTCACATTGTTGCAATGGTCCTATCGCAATGTATGTTTTCTGTATTCCAGAACTCTGACATTTGGCTTGGTACTGTTGGTGATCCCCTTCCTGCCAGCTAGTAATGTGTTCTTCAGAGTGGGTTTTGTGATTGCGGAGCGTGTGCTGTACCTCTCCTCAGCGGGCTACTGCCTCATTCTGGCCTACGCTGTGGGCTACTGTAGCTGCCACTGGAGGAAACACAAGGTATGTGGCCTGTTCTACACCAATTTCCCACTTATCGCCTCCTAATATTCACCATCAGACCATAATTCACTGTAACTAATGCTCAGTTGAGTTTGCGTTCATGTGTGATGTCTGTGGGCTGAATGCAGAGGCTGCTGAGAGCAGCCACGTTGACGCTGCTGTGTGTGAATGTGACTCGCTCTGCACAGCGCAGTCAACAGTGGAGGTCTGAA[C/T]AGAGTCTCTTCACCAGCGCCCTTTCTGTGTGCCCGCTCAACGCCAAGGTGAGACAGTACACCTGCCCTGTCATACTGCGAATAACTTTACATCATTGTTGAAATCTAGAGATGCACCGATATAATATTTTTATGGCCAACTCAGATTTTTTTTTAGGCAAATTGGCTGATTTCATTACCTATGTGCATTGTTATCATTTAAATTATATATATATTTAAATTCAGATTATTAAAAAATGTAAAATTTATTATTAATTGTATAATTTCTAAAGTAAAAATATAGGCCTGGGGAATTAATTGAAATGAAATCCCAAACGTGATTGAGCAAAACTACGGTTGTCATGCTCATCTGGTCAGGGAAGCAGGGTGTGATTAGTGGTAAATCTCCTCTAGAGACCATCTTTACTTTACAACATAGGCATTAATATAACCTTTGATTAGTCACCCATGCCCTATGAAAACATAATAATGACAGTGCAAATTCTCTGCTAGTACACAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21511
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000078681 Essential Splice Site 630 739 14 17
ENSDART00000127214 Essential Splice Site 630 739 15 18
ENSDART00000133427 None None 62 None 4
ENSDART00000136838 None None 55 None 3
ENSDART00000142904 None None 299 None 8
ENSDART00000146268 None None 32 None 2
Genomic Location (Zv9):
Chromosome 9 (position 32540728)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 31696674
GRCz11 9 31507420
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACCACAGCTTGGCATGGAACAATATGGTCATACTGTTAGACAACACTGG[T/A]AATGTACACCTGATTTTGTTTGTTTGATCAGATTTAAAAGATCAATGAAT
Long Flanking Sequence:
GAATCTTACAGCATGGATTTTTAATGTTTAGCGTGTTTCTTGCATCATTTTATCCACCCTTTCTTTGTAATACAAATCAACATGGGGCAGTTTATAATTAATTAGAGCAAGAAATTGTCTATTCCGCTCTAAATATTGCTCATTATGATGTGTAATAACGTGCTATTTTTGCTGCAATGATGATTTGATTCAAATGCTCCATGAATTATGAACTTCCTAGTGTTTAATATCCTAGTGTTTAATGCACATGCTTTGGATGTGTAGGAAATGCACGTTCAGATTTCCTCAGACCCCATGGTCATTATCTGTGAGAATAAAATGATTAAAACTGGACTGTGCAAAGCATTAAAGAGACATGTTTGTGCTTGTTTGTTTTGCCTTTAGTATGCAGACCTGAACCGTAGCATTGATGCGCTAAATGCCTGGAGGAATGCCACCATGCTGAAGCCTGACCACAGCTTGGCATGGAACAATATGGTCATACTGTTAGACAACACTGG[T/A]AATGTACACCTGATTTTGTTTGTTTGATCAGATTTAAAAGATCAATGAATACTATCATGGGCTGCACAGTGGCGCAGTTGGTAGCACGTTCGCCTCACAGCAAAAAGGTCGCTGGTTCGAGCATTGGCTGGGTCAGTTGGCGTTTCTGTGTGGAGTATGCATATTTTCCTTGTGTTGGCCTGGGTTTCCTCCGGTTTCCCCCACAGTCCAAAGACATTTAGGTGAATTGAATAAGCTAAATTGTCTGTAGTGTATGTGTGTGAATTAGTGTATGCTGGATAAGTTGGTGGTTCATTTCGCTGTGCTGACCCCGGATAAATAAAAGGACAAGCCAAAAAGAAAATGAATGAATAAATGAATACCATCACAAACAGAAAAACTGCAGTGGTCCCTCACTATAACGCAGTTCACCTTTTGCGGCCTTGCATCTACGCAGATTTTTTTAAAAAATTTGACATGCTTTTTTGTGTTCATTGTGTTCTGTGTCCTGATTAGAGCCT
Associated Phenotype:
Not determined