Busch Lab

ZMP

ptpn11a

Ensembl ID:
ENSDARG00000020334
ZFIN ID:
ZDB-GENE-030131-5911
Description:
tyrosine-protein phosphatase non-receptor type 11 [Source:RefSeq peptide;Acc:NP_956140]
Human Orthologue:
PTPN11
Human Description:
protein tyrosine phosphatase, non-receptor type 11 [Source:HGNC Symbol;Acc:9644]
Mouse Orthologue:
Ptpn11
Mouse Description:
protein tyrosine phosphatase, non-receptor type 11 Gene [Source:MGI Symbol;Acc:MGI:99511]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa41576 Nonsense Mutation detected in F1 DNA Not yet available
sa10099 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa41576
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081599 Nonsense 104 594 3 16
Genomic Location (Zv9):
Chromosome 10 (position 3442508)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3434702
GRCz11 10 3435006
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGAAAGAGAAAAACGGAGACGTCATTGAGCTGAAATACCCTCTGAACTG[T/A]GCCGATCCCACCTCCGAGAGGTGAGCACATACATACCTCATTATCTGTCT
Long Flanking Sequence:
CGATACAAATGATAAATAAATTGCATTATCTATGTAATCAAGTTATTTTAGAACACTGAGGTCTGTAGTACACGCTGTCATACAGAGCTGTGGAGACATTGGCGTAAATTGTTATGGAATGTGTTTTTTTAATTGGACTTTGAGTCTTTTATAAAGTTTGATATTATGTGTTTTGTATAGTTTGGCTACATAAATGTATTTTAATAAGTTCAGATTTAATAAACAACCAAATATGCAAATTTGTACGGAATCATTTTTTAAAATCCATATTTTTTACTTAAAATTACTTAAATCTTCTTTCATTTTTTTTTTCATCTCCTCACTAGGCGAAATGGCGCTGTCACACACATTAAGATTCAAAACACAGGAGACTATTACGACCTGTATGGTGGAGAGAAGTTTGCCACTCTTGCTGAGCTGGTCCAGTATTACATGGAGCATCATGGACAGCTGAAAGAGAAAAACGGAGACGTCATTGAGCTGAAATACCCTCTGAACTG[T/A]GCCGATCCCACCTCCGAGAGGTGAGCACATACATACCTCATTATCTGTCTGTCCTTACATGACAATTTGGGATGAGTTGTGTTTTATAGGCTTCTCTTTATTGGCTGTGAACTTGAACAAACCTTTTCTGACTGTCCTGTCTTTTTTTTTGCAACCACAAGGTGGTTTCATGGTCACCTCTCTGGTCGTGAAGCTGAGAAGCTGTTGACAGAGAAGGGCAAGAACGGAAGTTTCCTGGTGAGAGAAAGTCAGAGTCACCCAGGAGATTTTGTGCTCTCCGTACGAACTGGAGATGACAAGACGGACACCAGCGATGGCAAACCCAAAGTCACACACGTCATGATACGCTGCCAGGTAACAAAAAAAATAAATCAAATGCATTATTAACTATGTGGTTTTATATTGTCAGCCTGTTTTTTTTTTATCAGATGTGGATTAAAATCGTCTAGATCCTTAATATTAAGTAGACAATTAGTGTGCTCAAGTTGTGTGGAATTACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10099
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081599 Essential Splice Site 534 594 13 16
Genomic Location (Zv9):
Chromosome 10 (position 3453382)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3445576
GRCz11 10 3445880
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
MGTACAGCATTATATTGAGACTCTGCAGCGCCGCATAGAGGAGGAGCAGG[T/C]GTGTACACTTACAGTGGGGGAGATAAGTATTGAACACATAACCATTTATC
Long Flanking Sequence:
AGAACACATGAGAAAGAACGAACAAGAAAGAAAGTACACGAGGAAAAGAAAGAAAGAATGAATGAGAACGAACAAACAAGACAATAAGAAAGAAAGGACGATCGAGAAAGAATAAAAGAACAAATGAACAAGAAAGGAAAAAAAATGACCAGGTTTGTGGGCACTGCCGGAGATGAATCAAACAAAAATAGCTAGCAAGTGAAAAATCAAATATGTAGTAAAAATGTACATTTCACGCACGCACACACAAAGCAAAGAATGTTGGTCGACCACTTGGTTCTCTTAGTTAACTACAAGACCCTAAAATCAAACTTTAAAGGTCAGTCTAACCATCAGTTTGTGTTCAGGGGTGGACTGCGATATCGATGTGCCCAAGACTATCCAGATGGTGCGATCTCAGCGTTCAGGAATGGTACAGACTGAAGCACAGTATCGCTTCATCTACATGGCCGTACAGCATTATATTGAGACTCTGCAGCGCCGCATAGAGGAGGAGCAGG[T/C]GTGTACACTTACAGTGGGGGAGATAAGTATTGAACACATAACCATTTATCTCAGAAAACACATTTTTAAAGGCATCTAAAGGTGCTGTTGACTTGAAATTTTGACCAGATGTTGATAGCAACCAAATAAACTATAAAAGTAACTGTTTAGATTACAAATGAAGTTATGTGTAATAAAATAAAATGACACAGGGAAAAAGTATTGAACATATGAAGAACGTGAGGTGTAGAAAGCCAGTAAAAGCCCAGGCAGTAGCTGAAATCTCAGTAGTTCTTTAGCAACCCTCTGCCCTTCCTCAGTGTAAATGAATATCAGCTGCTTCAGTCCAACATCTACATTAGCAGGAGGATGAAGATGAAACCAGGGAAGACATTTCAACAAGACAATGATCCAAAACACAGCCAAATGCTTTCAGAGAAAAAAAATCAAGCTGTAGAATGGCCTAGCCAATCACCTGACTTAAACCCAGTAGAAAATACAAATTAAAGATCAGATTTGAT
Associated Phenotype:
Not determined