Busch Lab

ZMP

DNM2 (2 of 2)

Ensembl ID:
ENSDARG00000020270
Description:
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Human Orthologue:
DNM2
Human Description:
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Mouse Orthologue:
Dnm2
Mouse Description:
dynamin 2 Gene [Source:MGI Symbol;Acc:MGI:109547]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa19634 Nonsense Mutation detected in F1 DNA Not yet available
sa7417 Missense Mutation detected in F1 DNA Not yet available
sa38304 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa19634
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100171 Nonsense 25 876 1 26
Genomic Location (Zv9):
Chromosome 1 (position 59722626)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 58183161
GRCz11 1 58880164
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTTGATTCCCCTCATTAACAAGCTGCAGGACGCCTTCAGCTCCATCGGC[C/T]AGAGCTGCAACTTGGAGCTGCCGCAGATCGCGGTGGTCGGCGGGCAGAGC
Long Flanking Sequence:
TTTCAAAATGGTCTTTAGGATATTATGTGCATTATATTATATACATACCTGTTGATTTATGAGCAAAATACTTCATATTAACTCAATGTAACGCTGTCTAGCCGCAACTGTTATCTCTTCACCAAAGAGTAACGGAAAACTGTTCAAACTAACCCCACCTGTGCTTCATGACCACCCTCTGTCTACCAATAAGCTCTCGATGTTACTGACGGACATCAGCGATAGCCAATAGAAACGCGCGGATTGCATCCCAAGGGCGTTTCTTCAAAAGTTTATGGTGGTCTGCTGACCGGATATGAAAAGTTTCTCGCAGACAGTTTTCTGTGTTTCTGACAGCTGGAGTTCGTGTTTGTTTTCGTCCAGTCAAGCGAAGGCGGGTGATGAAGTGAGTTTCTCTGAGCTCCGAGGGTCTGATAAAGCTCGTCATCATGGGGAACCGCGGGATGGAGGACTTGATTCCCCTCATTAACAAGCTGCAGGACGCCTTCAGCTCCATCGGC[C/T]AGAGCTGCAACTTGGAGCTGCCGCAGATCGCGGTGGTCGGCGGGCAGAGCGCCGGTAAAAGCTCCGTGCTCGAGAACTTCGTGGGAAGGTAAAAGTCTTTACACTATTTAAATGTGGCTTTTTAAAATATGACATACGAACGTTTCGGTTGTTTTATTCTGTTATTATTTTGTTTATGTTACGGTGTTGTATTGAAATCTGACTCCTTCCCTGAAAAAAAGTTCTGATGGAGCTACAATCAAATAATTTAGCAAAATTACTAACTTATATAGAGCAAGATATGACATCAACATAAATTTGGTTTATATGTGACCTTATATGTGACCTTTTTAAACCTGTGTTTGTAGGGAGAGTAAATGTAATTTAATTTAAACCATTTTTGAGACTTAATTTAAACCATTCATAAGACCATTCATGAGACTTGTGTACTGTAATGTTTTTGTATAAGAAATTTGCTTAGAATGTTAGTTAGTTAGTTAGTTATTGTCTTGGTGGCCTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7417
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100171 Missense 86 876 3 26
Genomic Location (Zv9):
Chromosome 1 (position 59714364)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 58174899
GRCz11 1 58871902
KASP Assay ID:
554-4294.1 (used for ordering genotyping assays)
KASP Sequence:
CTATTGTAAACGTGTGTGTGTGTGTGTGTGTGWAGAATATGCMGAGTTCC[T/A]GCACTGTAAGGGCCGCAAGTTTGYGGACTTTGAYGAGGTTCGGATGGAGA
Long Flanking Sequence:
ATATATGTAAATACAAACTTTTATATTGGTTTTCACCTCATAGTTTCGTTTTGTTATTTGTTTGTTGTTTTCGGTTGTCTTGGGCTGTGTGTAAATGCAGTAATAATATGGTAAAGCCACAGTATCTTACACAACTTAAGAAACTGACTCAATGGGAATTTGCTGAACAGATATGCTTTGAGTTGCAAAATATAGTCGGTTCTGACCTTTTATTATTTAAACTGCAAGGCAAAAAGCTTGTTTTGAAGACTCTGAATGCATTATGAGAATTAATTGAGTGATTGAAAATACATAATGCATGATGTGTGTGTGTGTGTGTGTGTTTTTCAGGGATTTTCTGCCGAGAGGATCAGGAATCGTCACTCGCAGGCCTCTGATTCTCCAGCTGGTGAACAGTAAAGCTGGTAAATCCACAAAACATTTGATCAAAACCACAGTGTAGTGTATGAGCTATTGTAAACGTGTGTGTGTGTGTGTGTGTGTAGAATATGCCGAGTTCC[T/A]GCACTGTAAGGGCCGCAAGTTTGTGGACTTTGACGAGGTTCGGATGGAGATTGAAGCAGAAACGGACCGAATCACTGGATCTAACAAGGGAATCTCTGCAGTGCCCATTAACCTGCGCGTTTACTCGCCCAACGGTAATAACACACTTTAAGCTGTGTCTGAAATTGCTTATTATTCACCGTTAATCAATGTGAGCTAACGACACCAATATGGCTAGTTTTGATTTCATGTGGACTTTAGTGAGACGTGCAGACGTTCTAGTTTTGGATAAAGTGCCATTGATTTGTTTTTAACACTATTTTAATGGTGTTTTTCTCTCTTCAGTGCTGAATCTGACGCTGATCGATCTTCCGGGCATGACGAAGGTGGCGGTGGGTGACCAGCCGCAGGATATCGAGTACCAGATCCGGTGAGAGCAGTGGGGTTGAAGCTAAAGTGCTGAACTAATGGCAAACTCCTCCTTCAGAGACGAGACCTTGATCATTGTTTACGTTATATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38304
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000100171 Essential Splice Site 383 876 10 26
Genomic Location (Zv9):
Chromosome 1 (position 59708517)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 58169052
GRCz11 1 58866055
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCGAATAAACCGCATCTTCCACGAGCGCTTCCCCTTCGAGCTGGTGAAG[G/A]TGCGCTAACACCGAGCTCTAAATCATCATAAGCTGAAAACGATGATTTAT
Long Flanking Sequence:
CATTCTACAGCTTGATTTTCTTTCTCTGAAAGCATCTGAGAGTCTCCTCGGTTGTGTTTTGGATCATGTCTTGCTGAAATGGTTTGATCTTCATCCTCCTGCTGATGTAGATGTTGGACTGAAGCAGTTGAGGAAGGGCAGAGGGTTGCTGAAGAACTACTGAGAGATTTCAGCTGCTGTCTGGGCTTTCACTGCCCAACTACACCTCCCTTTCTTCATGTGTTCAATACTGTTTCCCTGCGTCATTTCTTTTTCCAAATTTCCAAGTCAACAGCACCTTTAGGAATATGTTTCCTGAGAAAAAGGGCGACGTGTTCAACACTTATGTCCCCAGCTGTATATAAATATACCTGTGTGTGTTCAGGATGGTCCAGCAGTTCGGTGTGGACTTTGAGAAGCGTATCGAGGGCTCTGGAGATCAGGTGGACACTCTGGAACTCTCCGGCGGAGCTCGAATAAACCGCATCTTCCACGAGCGCTTCCCCTTCGAGCTGGTGAAG[G/A]TGCGCTAACACCGAGCTCTAAATCATCATAAGCTGAAAACGATGATTTATTGTTGCTAATTATTATTTTATTTCATTCAGTTTTTCATTTATTGTGAGTTTTTAATTTTATTTCGGTTAACAAAATGTTTTTAGACCAATAGCTTTAGTTTTTGTTAAAGCAGTGATCACCTAACGTGTTCCTGGAGGGCCGGTGTCCTGCAGATTTGAGCTCCAGCCCTGATCAAACACACCTGAACAAGCTTATCAAGGTCTTACTAGGTATACTTGAAACACCCAGACAGGTGTGTTGAGGCAAGTTGGAGCTAAACACTGCTGGGACACCGACCCTCCAGGACCGAGATTGGTGACCCCTGGTTTAAAGTAACTTCTGTATATGAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Associated Phenotype:
Not determined