Busch Lab

ZMP

cdc42bpb

Ensembl ID:
ENSDARG00000019383
ZFIN ID:
ZDB-GENE-030131-3647
Description:
serine/threonine-protein kinase MRCK beta [Source:RefSeq peptide;Acc:NP_001038590]
Human Orthologue:
CDC42BPB
Human Description:
CDC42 binding protein kinase beta (DMPK-like) [Source:HGNC Symbol;Acc:1738]
Mouse Orthologue:
Cdc42bpb
Mouse Description:
CDC42 binding protein kinase beta Gene [Source:MGI Symbol;Acc:MGI:2136459]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa29326 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa36997 Nonsense Mutation detected in F1 DNA Not yet available
sa12889 Nonsense Available for shipment Available now
sa43407 Nonsense Mutation detected in F1 DNA Not yet available
sa6626 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa29326
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049437 Essential Splice Site 199 1708 5 36
Genomic Location (Zv9):
Chromosome 20 (position 18545083)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 18573340
GRCz11 20 18472923
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGATGGTTCTCGCCATCCACTCCATCCATCAGCAGCGCTACGTACACAG[G/A]TGACACGAATACTGTGTTTGTGTGTATGAATGGGAGTAGTATGAAGTGCC
Long Flanking Sequence:
ATATAAATGCATATTACATTACATAACAAACTACATTCATAAATTAAATGTCAATTATTATCATATAACCTTAAGTTTAATAAATTATTGAGCACGTGTACATTATTATCAGGGAAATGGATAAGTTTACCATGATGAATTTTTTTTTATTTCGCAGCTTCTGATAGCACAGCCTCTAACACAGTAATTCAGGAGGTCACGGCACAATGCGTCCTGTGTGGTTTAATGATAAATATATTGCAATCACACTGCTCTTTGATGTCTTGCGTTTGATATTATGAAGTGCTGAGTCGGTGTTTGTGTAATTGAATGGTGTTGTGTGATAAGAGATGATAATGTCTCCTCCTGCAGTACTTGGTGATGGATTATTACGTTGGCGGTGACCTGCTGACGCTGCTTAGTAAATTTGAAGACCGGCTGCCGGAGGACATGGCCAAGTTCTACGTGGCGGAGATGGTTCTCGCCATCCACTCCATCCATCAGCAGCGCTACGTACACAG[G/A]TGACACGAATACTGTGTTTGTGTGTATGAATGGGAGTAGTATGAAGTGCCACATAGAATTTAAATCAAACTTTGCTTATCGACGTATACATAAAACACGTGCATATACACCTATTCACAAAGTGGCACAATTTCCATCTAAACCTGAAAGAGATAAAATATGATCTTTGTGGTATTTTAATAGGGACATCAGAAACTTAATTTACCTCTTGTAAATAGGGGCGTAATAGGTCCCCTTTAAATAACAAATAGCCTCTTGCCTATTTCTGTCTGTTTTTAGTCAGAATAAGGCCACATTTTATGCATATGGCCATGTTTTTAATGCTAGACTAGTTCCAGACAAAACATCCCATATCCCACATCCCATAACAAATTATGTCTATATGTTTGAATGTAATCACAAGCAAGTCAGAGTGGTCATTAGCATGGTTTGAGTGATGGGCACACTGGTGGGATCTCCTGTCCACTCCCACATGAAATATTTAATGAAATGACCGCAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36997
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049437 Nonsense 282 1708 7 36
Genomic Location (Zv9):
Chromosome 20 (position 18532124)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 18560381
GRCz11 20 18459964
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGCTGGGCGTTTGCATGTATGAGATGCTGTACGGCGAGACACCCTTTTA[C/A]GCCGAATCCCTGGTGGAGACCTATGGAAAGATCATGAACCATGAGGTGCG
Long Flanking Sequence:
TACTGGATTAAGATCTTCTAGGGGATCGAATTGAGATCGCGATCTTTTTACGATTAATTGTGCAGCTCTAATCGCAATACTACTTGGTATCACAATACTTCAGCTGGTATAGTATAGTAACATAAATTAATGGTATCATGGCAACCCTACAATGGTACTATCTAAAAAGTAATCTAACCTTGTGAAGATTTGACATTAGTGGTTTTGTAAAAAAAATTCTTAAGATATTGATGATAATAAGAAAAAAATGTTATTATAAGTGAGTATTACCTCATAATTTCACCCTGCATACACAGATGCAAACTTGTCCCGTCTCATTTGCGACGTCACTTATCCTCTGTGCAGGTCCAATCTTCAGTGGCTGTGGGCACACCAGACTACATCTCTCCAGAGATCCTGCAGGCCATGGAGGACGGCATGGGGAAATACGGGCCGGAGTGTGACTGGTGGTCGCTGGGCGTTTGCATGTATGAGATGCTGTACGGCGAGACACCCTTTTA[C/A]GCCGAATCCCTGGTGGAGACCTATGGAAAGATCATGAACCATGAGGTGCGTATATTTTTGGTTTCACCCAGTTTAAACGTTCCCCGCCACTGACCCATATTTGAGTCTAGGGAAATAGACATTTTTCATTGTAGGAAAAGCATGAACTGCAGCGAATCCGATTAAAATATTTATTTATAGGCAATAAAAATAAAGCTTAGGCTAATTATCGTGACAAATAGCATCCCGCCTGGAACTCTGTTGGGACATATAACATGGCTCATAAAATCTGAACTGCCCTAATTTTTATCAGGACATCTGGCCGCCCCTAAACCACCACTGTTTTTTCCTATTTGTCTGTGCTTTGGTTCTTTTAATAGGAATAGATGCCCCTTTACAAGAGATGCAATTCTGATGGCTTCAAAATGTTTCTGTGAAGTTTCAACCTTAAAAGCCCCACATATCACATATTAAAGCTTGTCAAAGTTGCCCCTTTTTGGGTGTAAGTGAGTGTATGTCTC
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa4887
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049437 Nonsense 473 1708 10 36
Genomic Location (Zv9):
Chromosome 20 (position 18526809)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 18555066
GRCz11 20 18454649
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTCCCAGAATCCACTCAGGCTGTTCAATCTCTTCATGGCTCTGGTCGA[G/T]GAGCYGGCACTCTCGGACGAGATAAAGAGATTAAAAAACTTAATGAGGAA
Long Flanking Sequence:
TATAAAACAAGTCATTTATGTCAAAAATGTCAAAAACTGTTGTTTCAATTCTATTCTAAGTAGTTTAAACAAGCAGCAAAAGTTATTTTTCGAGTATATTTTAGCTGTACATTTATTAGAAAATAATTGCATACCTTAGAAAGCTCATTGGCCAATCAGAATCAAGCATTCAACAGCACTGTAGTATAAATATAATTAAAAGCCTGTATTAAGTCTGTTTATCGTTCAGAATAAATTGTGTATCTTCTGATAAAGATCATATAACTTTATTCATATAGATTACTTTTATGAAGTCTTTATGTAAATGATTGAAGCATAGAAGTATTGGAGTGAACTGTAACTTTCAGCTCATGTTCTTCAATGTTGAGGTGTTAATAGTTCTCTTGTTAATTTTATACGTGCATCAGTGAAATGTATTTATAATATGCGATTCCTACTTGCTCTATGCATTTTTCCCAGAATCCACTCAGGCTGTTCAATCTCTTCATGGCTCTGGTCGA[G/T]GAGCCGGCACTCTCGGACGAGATAAAGAGATTAAAAAACTTAATGAGGAAATCGATCGGCTTAAAAAGAAACTGGCAGGTAATGGGCCTCTTGTTATTATCTCTAGATTTCTGATATGATCTGAAGTCGGTTATTATGAGTCATGTCAAAGCACTATGCACAAGCTTGCGTTATAGTGTAACTGTGACCACACTTTCATACAGTTCTGATAAGAATATTAGGATCAGTCCATGCTGCTCTTACTTTTCACAGTTTGTTCATTTGATTTGGCTATGCATTTGTGTCAGTCTCATCCAATCAGCCTGTCTCTTCAGACTCTGATAGGCTGGAGCACCAGTTGGAGGAAGCAGTGACTCTTCGACAGGACTTTGAAAGTTCCTCCACCAAACTAAAAGCCCTGGACAAGCAAGTCAAAGCTCTCAAGCTGGAGAAAGAGGATATTCATAAGGTACGAGTGGCTTGTGAATTGAATTAACAGCCAAAAAGGATACATGTTGGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12889
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049437 Nonsense 1105 1708 25 36
Genomic Location (Zv9):
Chromosome 20 (position 18491632)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 18519889
GRCz11 20 18419472
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGCTTATACAGCCTTGTTTGTTGCTCCTCTTTCAGATCCCGAAGCCCACC[G/T]GAGTGAAGAAGGGCTGGCAGAGAGCATATGCTGWAGTKTGTGACTGTAAA
Long Flanking Sequence:
ACTATAAATTAAATATTGTGTGCACACATGTTTATAGTTTTTAAAACAACAAAAGTACACTATTTTGGCTTTTACATGTGATGGGAAGTCACTGGTTGTGTGAATGAACCTGAATCTTCCCAATAGAATTTCTATTATGCATTATTTTCAAGAAGCTATAATGGGTCTTGTTTTGTCTGTACTAATAGTTATTTGGATATTGGTAAAACCTGAATGAATAACAATTAACTTGTTGAATAGCATATTATATATGTTTGTTTTCTATTTTGTTGTGATACTTTTATAATTATTTATGAATTGTTATAAGTTATATTAATTGTTATAATACAGTTTAATATCAATATAAGCAATTATTCAAGAAACAAATTCAGGTTTTAGCCAAGTGCATTTTTGAGTTTTTAGTTTTGGACCAGAGTTTTCGTTTCGATGCATCCCTGCTAATTATCCATTAGCTTATACAGCCTTGTTTGTTGCTCCTCTTTCAGATCCCGAAGCCCACC[G/T]GAGTGAAGAAGGGCTGGCAGAGAGCATATGCTGTAGTGTGTGACTGTAAACTCTTTCTCTACGAGGTGCCAGAAGGGAAGTCCACTCAACCTGTCGTGATGGCCAGTCAGGTCCTTGACTTGAGGTGAGGACTAGTCACATTTATTTTTTATTTTTTTATTCTTTCTTTTATATACACACACACACATAGATAGATAGACAGACAGACCGACCGACCGACCAACCGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATAGATACATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATAGATAGATAGATAGATAGATAGATAGAT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa1652
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049437 Essential Splice Site 1146 1708 25 36
Genomic Location (Zv9):
Chromosome 20 (position 18491506)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 18519763
GRCz11 20 18419346
KASP Assay ID:
554-1592.1 (used for ordering genotyping assays)
KASP Sequence:
GGAAGTCCACTCAACCTGTCGTGATGGCCAGTCAGGTCCTTGACTTGAGG[T/C]SAGGACTAGTCACATTTATTTTNNNNNNNTTATTTTTTTATTCTTTCTTTTATATAC
Long Flanking Sequence:
AATTTCTATTATGCATTATTTTCAAGAAGCTATAATGGGTCTTGTTTTGTCTGTACTAATAGTTATTTGGATATTGGTAAAACCTGAATGAATAACAATTAACTTGTTGAATAGCATATTATATATGTTTGTTTTCTATTTTGTTGTGATACTTTTATAATTATTTATGAATTGTTATAAGTTATATTAATTGTTATAATACAGTTTAATATCAATATAAGCAATTATTCAAGAAACAAATTCAGGTTTTAGCCAAGTGCATTTTTGAGTTTTTAGTTTTGGACCAGAGTTTTCGTTTCGATGCATCCCTGCTAATTATCCATTAGCTTATACAGCCTTGTTTGTTGCTCCTCTTTCAGATCCCGAAGCCCACCGGAGTGAAGAAGGGCTGGCAGAGAGCATATGCTGTAGTGTGTGACTGTAAACTCTTTCTCTACGAGGTGCCAGAAGGGAAGTCCACTCAACCTGTCGTGATGGCCAGTCAGGTCCTTGACTTGAGG[T/C]GAGGACTAGTCACATTTATTTTTTATTTTTTTATTCTTTCTTTTATATACACACACACACATAGATAGATAGACAGACAGACCGACCGACCGACCAACCGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATAGATACATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATACATAGATACATAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43407
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049437 Nonsense 1265 1708 28 36
Genomic Location (Zv9):
Chromosome 20 (position 18486665)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 18514922
GRCz11 20 18414505
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACGAATTGTCTTGGGGACAGAAGATGGCCTTTTTGTAGTCGAGATCACC[A/T]GAGATGGTATGAATACTGTACATTCCTCGCTCAGTTCTTATCTTTTTATT
Long Flanking Sequence:
TATATATATATATATACACACACACACACACACAAACACATACATATATATATTTATATGTATGTATGTATGTATGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACAAATGCTGCTTTTATTTTTATTATTACCTTTTTTGATCCCAGGTTATTTTGGTCAGCATTTTTTATTGTATAAGTCAGTGTTTCTTCAACCACGTTTCTTGAGGGCCACCAACACTGCATTTTTTGGATGTCGCCTTAGTTTGTCACACCCATCACAGGTCTTTTAGTCTCTGCTATTGAGTTGATTGAAGCCTTTGGGTGGGCGCCCCCTAAGACATTAGTGACTGAAACACTGATGTTTACAAATCACATCCAGGAATGTTCCATTTTTTAAAAAATAATATCTGTTGTTTTTTCCACTGCAGATCGAGAACGAATTGTCTTGGGGACAGAAGATGGCCTTTTTGTAGTCGAGATCACC[A/T]GAGATGGTATGAATACTGTACATTCCTCGCTCAGTTCTTATCTTTTTATTTATTTTTATTTCCATTATAAATCCAATCTCCCATGATGTTTTTCAGTCATTGTTCGTGCCGCTGACTGTAAAAAAGTCTGCCAGATCGAGCTCATCCCCAAAGAGAAGATGGTGGCCCTGCTTTCTGGCCGTAATCGCCATGTCCATTTATACCCCTGGGCGGCACTAGAGGGCGCTGAAGGGGGTTTCGATGCCAAGCTGACAGATACGAGAGGCTGCCAGGCCATGACCATCGGTAACCTCCGCCCTGGCGGTCCAGCGTGTCTCTTTGCAGGCGTGAAGCGGCAGGTTTTCTGTTATGAAATCACACGAGCGAAACCCCATCATCGCAAACTCTGGGAAGTGCAGGCGCCAGGGGTCGTCCAATGGCTGGGGATAATTCGAGAACGGATCTGCGTAGGTTACCCATCAGGCTTTGCTCTGCTGGCCATGCAGGGAGAATCGTCGCCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6626
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049437 Nonsense 1671 1708 36 36
Genomic Location (Zv9):
Chromosome 20 (position 18465658)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 18493915
GRCz11 20 18393498
KASP Assay ID:
554-4975.1 (used for ordering genotyping assays)
KASP Sequence:
TCTAATTTTGTTTCTTTACCTGGTCTTTCCTCTGTAGCCCGACTCAGAYT[C/A]GACCAAGCATTCCACCCCCTCGAACAGCTCCAACCCCAGCAGCCCACCGA
Long Flanking Sequence:
TACAGTCGTTACTTAAGATCTGCTTCCTTCATGTCTGTCACTGTGCTGTTTATCGGAGGAAGCCGAGGTGGCGATTGAGGCATACTCTGACAGGCACATGGGAACGGTGGGCGGGGAGAACTAGCATTAAAGGCACAGGCAACAAAAACAGCTACACAGTGTTCAGAGCAGAAAATGCAGTATTCTGAAAGCTACAATAAATGATCTGATGGGGGTTTTGAGCTGAAACTCTACACAAACACATTCTGGAGACAAAAAAAAAGACTTTTCTTAAACCTTAAAAAGGGGTGAAATAGGTGCCTTTTAATTTTAGTTAAAGATTTAGTCATTTCGAATCTATTCTAATCTAGTCCATTCTAATAGCTAATAATGATCATTTTATTTCAACCACATAAAGTTAATGATAACAACACAAATGTAAACACCTACCCGGACCCAAGTGTGTTTTTTTCTAATTTTGTTTCTTTACCTGGTCTTTCCTCTGTAGCCCGACTCAGACT[C/A]GACCAAGCATTCCACCCCCTCGAACAGCTCCAACCCCAGCAGCCCACCGAGCCCCAACTCTCCCCACCGCAGTCAGCTGACTCTGGACAGCCTGGATCAGTCCCTGGATGGTTGAAAGAAAGAGGACGCGACCCTTCATAAGCGTCCCACACACACACACACACCCTGCATATCCACCTTCTCTGCAAGGACTTGCTCAAGAAGTGCCAAGACCCTTCCAGCTCACGGGCCCAAAGGTTTAAACGATAAAAAGAAGCCTCAATCGCCACAAGCAGAGAGTGTCAGGTGTGTGTGTGTCCGAAAAAGAGAAAACAAATCATCAGAGCCACCAAAATAAGAGGTAAAAGCCCCCCTCTGGTGGAAATTTCACGGTATTACACTACCCGGCTCAGATTAGCAGCATGACAGACTTTTATTTTATTTTATTTTAAACCTAATTTCACGCCATGCTCCTGCAAGTTGTTTTTTTTAATTGTTATTTACTTTAGTAAGTGAAAATG
Associated Phenotype:
Not determined