ZMP

thop1

Ensembl ID:

ENSDARG00000019233

ZFIN ID:

ZDB-GENE-041010-216

Human Orthologue:

NLN

Human Description:

neurolysin (metallopeptidase M3 family) [Source:HGNC Symbol;Acc:16058]

Mouse Orthologue:

Nln

Mouse Description:

neurolysin (metallopeptidase M3 family) Gene [Source:MGI Symbol;Acc:MGI:1923055]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa38786	Splice Site, Nonsense	Mutation detected in F1 DNA	Not yet available
sa2561	Nonsense	F2 line generated	Not yet available

Mutation Details

Allele Name:

sa38786

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Splice Site, Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000003839	Splice Site, Nonsense	150	630	3	13
ENSDART00000123818	Splice Site, Nonsense	150	690	3	14

Genomic Location (Zv9):

Chromosome 10 (position 15441967)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	15455274
GRCz11	10	15413393

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATGTTGAAGTGAGCATGAGGGCGGACGTGTTTCAGAGACTTTTAGTCCTG[C/T]AGGTACATCATGTCATATTCAACATGAAAGCTAAATTTAATTCTGATAAT

Long Flanking Sequence:

ATAATGACAATAAAGTTGAATTTAATCTAATCTAATCCATATTATTCAGCAAAAGCCTGATTATTATACTGGAATGAGATTATAGTTTGCCTTGGTCAATATAACTGCAGCAGAGTGAAGCTTTAAATGAGAAAATTATTAAAACTCTTTGGTCATTTTTGAACGAGATGCTTATAGTCTAATCCAATTTGATGATCTATGCTAACCTAAGCTAAAAGTAAATAAATAAGTAAATGAGTAAATAAGGCTCTTTCTAAAAAAGTGGAGTGAAATTTTAATGATATGGAAACCGTTATATATATATATATATATAATGCTGTGAAGTGAAGTGAAGTTTTCTGTGCTGTGTTTCAGCTTCTCGTCATGTGTTGGACTTCCCCCAGTATGTCGCTCCATGTAAAGAGGTCAGGTTTGCGAGCACTGAGGCTGATAAACGTCTTTCAGATTTCGATGTTGAAGTGAGCATGAGGGCGGACGTGTTTCAGAGACTTTTAGTCCTG[C/T]AGGTACATCATGTCATATTCAACATGAAAGCTAAATTTAATTCTGATAATTCTAGTGTGGTAAAAAAAACACTGTCACTTTCCAGAAGAAAAAAAGGAAACCAGTTTTGATACTGATAACTGATAAACCTTTAAAGACAGAAGTTGTTAAAATATTGCAAATGGTTTTATTGAGATTATTGTATCTCCTAATTTCACAGATAGTACAACAATACTACCTATACTACAATCCCAAATCAAACAAAGTTGGGACCAGATATGAACACAAATTATTTCATGTTTTGTCTGGTCAACTTCATTTAATTTGTAAATATGCATCCTTTCCTATTGGGACAGGAGCAATTTAGGGCTAGTAATCAGGTCAATTAGTTAAATAATGATAATGTCAACAGATGATTGTAATTAAGATTGGTTACAAAAGCAGCATCAAAGAAAGGTCTAGTTCAGCAGTCTCAAACTCAAGGGAGGCCATTTCAGTGACAGATTAGAAAAATCTGAAGG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa2561

Status:

F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000003839	Nonsense	167	630	4	13
ENSDART00000123818	Nonsense	167	690	4	14

Genomic Location (Zv9):

Chromosome 10 (position 15445779)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	15459086
GRCz11	10	15417205

KASP Assay ID:

554-3188.1 (used for ordering genotyping assays)

KASP Sequence:

AGGAAAAACAGTCCTGTGATTTACTGCCTGAGTCAGAGAGATTCCTGGGA[C/T]GACTTATAAAGTTAGGAAAACGGAATGGATTACATTTGWCTGAGGATATA

Long Flanking Sequence:

AAAAAGACATTTTGCAAGTCGGCAGCCAGGTCCAGTTTCATAGAGGTGACCTATAAAATGAGGCATTTGGCAGTGCTGGACAAACCCATTAAGACTTTGTACAAAACAGTTTCATGTTGCGCTTTTACAAATTAAAATGATGATCTCATTGTAAAAATCTCCCGTTGTAGTGAGCGTCCTGCTGTTCTACTCATTTGATGAGGCTGTCCTCTCTCCCTGGTTTTTACTACCTGTTTAATTGAGCTGTAAATGAAATGATCGCAATATTTCTCTAGTATGGACTCTTCACTGTCCTCATTGTGACCCTGTTGAAGACTCTGTTCATAGGAAAGCATGTGACACCAATGCGGTGTCGGACTTGTATGTTTGGCCAGTTGTCAAAAACGTAGAAGTAAACTTAACTGGTGGCATTCACTGTGCATGCTTCAGCATTTCCCACTTTATCTTCATAGGAAAAACAGTCCTGTGATTTACTGCCTGAGTCAGAGAGATTCCTGGGA[C/T]GACTTATAAAGTTAGGAAAACGGAATGGATTACATTTGTCTGAGGATATACAAGATGTGGGTTTGTTTGGTTTTTTTTGTTTACTACAAACTTAGCTTTGAGGATGAACTGACAATTCTTTTTAGACTCTATGGAACGTATTGCTTGCAATTTTAGTTACTGTAGTCATCTCAACAGTGTTAACCTTAGTGCAACTTGTCAGTTATAGAAATCCTGTTAAAAAGAATTTTAATAATAATGTTTTACAATAATTCTGATAAGAAGCATTAAAAACTAGAGAATATAAAATTAGTTTAGAATTGTATTTTAAGTTATTACAACTATAAAAATTAACATATACTACTATTTTACTACTACTACTAATAATGATGATGATAACTATACTTAATAATATATGTTTTAAAATAATTATGAAGAAATATTAAGTATTAAGTAACAAAATTTGATTAGAATTGTAATTAAAACAACTTAAAAAACAAATATCAGAATTAATTTGAAAC

Associated Phenotype:

Not determined