ZMP

krt18

Ensembl ID:

ENSDARG00000018404

ZFIN ID:

ZDB-GENE-030411-6

Description:

Keratin, type I cytoskeletal 18 [Source:UniProtKB/Swiss-Prot;Acc:Q7ZTS4]

Human Orthologues:

AC090051.1, KRT18

Human Descriptions:

Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:C9JEA8]
keratin 18 [Source:HGNC Symbol;Acc:6430]

Mouse Orthologue:

Krt18

Mouse Description:

keratin 18 Gene [Source:MGI Symbol;Acc:MGI:96692]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa24263	Nonsense	Available for shipment	Available now
sa37630	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa24263

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000020750	Nonsense	247	460	3	7
ENSDART00000127667	Nonsense	218	431	3	7

The following transcripts of ENSDARG00000018404 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 23 (position 10456611)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	10415413
GRCz11	23	10350383

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGAACCTTGAGAGCGAGATCGAGGCCCTCAAAGAAGAGCTCATCTTCCTT[A/T]AGAAGAACCATGACAATGTGAGTACACATCTGGCACATCTGGAAACATTT

Long Flanking Sequence:

CTAAGCAAACCAAGAATGATGAAGCTCCAGTTAAAAAATATTTGGTCAGTGATAGTCATTCATTAAAAGATGCAAATTTGCCAGAGAGTTCAAGTCAGGTGAGGTTTGTGTGTCATAGCTGCACGATGGTGATGTCCCATCTCTTTGGAGCAAGATTTCTGACTGACTCCAATGATTTATTTTTTGGCTCTAGATCTTTGATGCCACCACAAACAATGCTCGTCTAGTGCTCCAGATTGACAACGCCCGCCTGGCAGCTGATGACTTCAGAGTCAAGTGAGTAGCAACAAACAAATCATTTTGACCTCATGGGAAGCTCTTAAAATCAACAGAGACCCATTGACCTTTGTTGTGCCTGCAGGTATGAATCTGAGCTGTCCATCCGCCAAGGTGTGGAGGCCGACATCACCGGCCTAAGAAAGGTCATCGATGACACCAACCTGAACCGCATGAACCTTGAGAGCGAGATCGAGGCCCTCAAAGAAGAGCTCATCTTCCTT[A/T]AGAAGAACCATGACAATGTGAGTACACATCTGGCACATCTGGAAACATTTGTCCACCTCGTAATTCGTTAAAGGCGTTGCTTTAAGACATATTTTACGGCTTCTCCACCCAACAGGAGGTAATGGAGCTTCGTAACCAAATCTCCCAGTCAGGAGTGCAGGTGGATGTTGATGCTCCTAAGGGACAAGACCTTTCCCAGATCATGGAGGAGATCAGAGCCAAGTACGAGAAGATGGCCCTGAAGAACCAGGAGGAGCTGAAGGCCTGGCATGAATCTCAGGTATATCCTAAAAGACAACCCTTCATTTCCAATGAACTCTAACATGTTGAAGCTTTGGCTAATGTGAAATTAAATGTTCTCTCTAGATCACAGAGGTTCAGGTACAAGTCACGCAGAACACAGAGGCCCTCCAGGGTGCCCGTTCAGAGGTTAACGAACTTCGCAGACAAATTCAGACATTGGAGATCGAGCTGGAATCACAGAAGAACCTGGTGAGTTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa37630

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000020750	Essential Splice Site	252	460	3	7
ENSDART00000127667	Essential Splice Site	223	431	3	7

The following transcripts of ENSDARG00000018404 do not overlap with this mutation:

Genomic Location (Zv9):

Chromosome 23 (position 10456629)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	10415431
GRCz11	23	10350401

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCGAGGCCCTCAAAGAAGAGCTCATCTTCCTTAAGAAGAACCATGACAAT[G/T]TGAGTACACATCTGGCACATCTGGAAACATTTGTCCACCTCGTAATTCGT

Long Flanking Sequence:

ATGAAGCTCCAGTTAAAAAATATTTGGTCAGTGATAGTCATTCATTAAAAGATGCAAATTTGCCAGAGAGTTCAAGTCAGGTGAGGTTTGTGTGTCATAGCTGCACGATGGTGATGTCCCATCTCTTTGGAGCAAGATTTCTGACTGACTCCAATGATTTATTTTTTGGCTCTAGATCTTTGATGCCACCACAAACAATGCTCGTCTAGTGCTCCAGATTGACAACGCCCGCCTGGCAGCTGATGACTTCAGAGTCAAGTGAGTAGCAACAAACAAATCATTTTGACCTCATGGGAAGCTCTTAAAATCAACAGAGACCCATTGACCTTTGTTGTGCCTGCAGGTATGAATCTGAGCTGTCCATCCGCCAAGGTGTGGAGGCCGACATCACCGGCCTAAGAAAGGTCATCGATGACACCAACCTGAACCGCATGAACCTTGAGAGCGAGATCGAGGCCCTCAAAGAAGAGCTCATCTTCCTTAAGAAGAACCATGACAAT[G/T]TGAGTACACATCTGGCACATCTGGAAACATTTGTCCACCTCGTAATTCGTTAAAGGCGTTGCTTTAAGACATATTTTACGGCTTCTCCACCCAACAGGAGGTAATGGAGCTTCGTAACCAAATCTCCCAGTCAGGAGTGCAGGTGGATGTTGATGCTCCTAAGGGACAAGACCTTTCCCAGATCATGGAGGAGATCAGAGCCAAGTACGAGAAGATGGCCCTGAAGAACCAGGAGGAGCTGAAGGCCTGGCATGAATCTCAGGTATATCCTAAAAGACAACCCTTCATTTCCAATGAACTCTAACATGTTGAAGCTTTGGCTAATGTGAAATTAAATGTTCTCTCTAGATCACAGAGGTTCAGGTACAAGTCACGCAGAACACAGAGGCCCTCCAGGGTGCCCGTTCAGAGGTTAACGAACTTCGCAGACAAATTCAGACATTGGAGATCGAGCTGGAATCACAGAAGAACCTGGTGAGTTTGCTTTCTTGTACTCATCG

Associated Phenotype:

Not determined