Busch Lab

ZMP

pdpk1b

Ensembl ID:
ENSDARG00000018285
ZFIN ID:
ZDB-GENE-040426-1820
Description:
3-phosphoinositide dependent protein kinase-1b [Source:RefSeq peptide;Acc:NP_991262]
Human Orthologues:
AC141586.1, PDPK1
Human Descriptions:
3-phosphoinositide dependent protein kinase-1 [Source:HGNC Symbol;Acc:8816]
Putative 3-phosphoinositide-dependent protein kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q6A1A2]
Mouse Orthologue:
Pdpk1
Mouse Description:
3-phosphoinositide dependent protein kinase 1 Gene [Source:MGI Symbol;Acc:MGI:1338068]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa17656 Essential Splice Site Available for shipment Available now
sa24545 Nonsense Available for shipment Available now
sa39462 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17656
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003789 Essential Splice Site 87 537 3 14
Genomic Location (Zv9):
Chromosome 24 (position 38834987)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 37434205
GRCz11 24 37321925
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTACAGGTTGTCTTGGCAAAGGAACACACGACGGGGAAGGAATATGCAA[G/A]TAAGTTGTCYTGTCATTTAGGGCTGTGCATTATGATGATGATGATNNNAT
Long Flanking Sequence:
CACACATACATACATATTCTGCTTAAAATATTTTTTATAAAAATGTTATCTTATGTAATGCAATAATTGCTATGTTTCTCCCATTTAGGATTTAGTAGTTATTAGTATGAGTTATATTTAATAGTTCCTACTATACTTGTGTTTTTCTCTCATCAGTATGATGTTGCATCCCTCCACTCCTCTGTTCTCATCTCCTGTCCATCCATGGTAAGAGGCCAGCAGGACACGCCTCGTCTCCACGGCAACAGCATGGAGGGACCGGCACCAAACGCCCAGCCCGCCCAGCCTCGCAAGAAGAGACCCGAGGACTTCCGATTCGGCAAAATCCTGGGAGAAGGCTCTTTCTCTACTGTACGACACACACACTCCGACTGCGCCACACACGCACACACCTGACAGAGCCCAGAGAGTGTGACTCTGTTAATGGACTAACCTTTGCTGTCTTTTATATTTACAGGTTGTCTTGGCAAAGGAACACACGACGGGGAAGGAATATGCAA[G/A]TAAGTTGTCCTGTCATTTAGGGCTGTGCATTATGATGATGATGATGATATACTCTCACCGGCCACTTTATTAGGTACACCTGTCTGTTGACTGGTTGTTAACGCAAATTTCTAATCAGCCAATCAAATGTCAGCAATTCAATGCATTTAGGCATGTAGACATGGTCAAGACGATCTGCTGCAGTTCAAACCGAGCATCAGAATGGGGAACAGAGGGGATTTAAGTGACTTTGAACGTGGCATGGTTGTTGCTGATCTACTGGGATTTTCATGCACAACCATCTCTAGGGTTTCCAGAGAATGGTCTGAAATAGAGAAAATATCCAGTGAGCGGCAGTTCTGTGGGCGCAAATGCCTTGTTGATACCAGGGGCCAGAGGAGAATGGCCAGACTGGTTCCAGCTGATAGAAAGGCAACAGTAACTCAAATAAGCACTCGTTACAACCGAGGTCTGCAGAAAAGCATCTCTGAACACACAACACGTCCAACCTTGAGGCGGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24545
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003789 Nonsense 109 537 4 14
Genomic Location (Zv9):
Chromosome 24 (position 38832918)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 37432136
GRCz11 24 37319856
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAAGCGCCACATAATGAAGGAGAATAAAGCGCAGTATGTCAAGAGAGAA[C/T]GAGACATAATGTCACACCTGGATCATCCGTTCTTCGTCAAACTCTACTTC
Long Flanking Sequence:
ATTTCCGAATATATACTTTAAAATAAATTTTTTAAAAAGTCACTTAAATGTGGTGATTATAAATAAACTATTAATTGATTGAATGCAGAAATGGCACTATATTGTGATGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATACATACATACATACATACATACATAAATACATATATATATATATATAAATACATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATACATATATATATATATATCAGGATCTTAAATGACTTATCATGATTTAATACTTGGGCACATCGTGCAGCTCTTTAATAGCCTTTGCACTGACATTTGAGCATGTACTGGAAAGTGTTTGTGTTTCCTCAGTTAAGATCCTGGAGAAGCGCCACATAATGAAGGAGAATAAAGCGCAGTATGTCAAGAGAGAA[C/T]GAGACATAATGTCACACCTGGATCATCCGTTCTTCGTCAAACTCTACTTCACCTTTCAGGACGAGGAGAAGCTGTGTATCCTTCACACAAACTCTGATGCTCAACTAGTATGGGTTGCACAGCGTCAATATTAAGGAGCACAATAAAGATGGCTGTTGTGTTTCTTTCAAATGAGCTAATATGACATGGACATGCTTATTTTTGTGGCATTTTTTACACTAAAAATACATGTTTTTAATTATTTTGAGCACATTTTAGGTAGCTTGACGTTTATCATTAGGTTTGTATGGTATGCCGTTTATTGAACTATCCCTTTAAGATGTTACTCAAGATATATCTATTAATGGCATATTAGGCTTCTCCTAATTTCTTTCAGCACTATACATGTATACATGTCAGCATATGTTAATGAAGGATTTGTCAAAGCCTTGCTTATGTCAACGCTGCATTTTATAGCTTGTTTTCCTGAATGTCGTGTCAGATTTTGGATTAAGCTACGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39462
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003789 Essential Splice Site 134 537 4 14
Genomic Location (Zv9):
Chromosome 24 (position 38832841)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 37432059
GRCz11 24 37319779
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCGTTCTTCGTCAAACTCTACTTCACCTTTCAGGACGAGGAGAAGCTGTG[T/A]ATCCTTCACACAAACTCTGATGCTCAACTAGTATGGGTTGCACAGCGTCA
Long Flanking Sequence:
ATTGAATGCAGAAATGGCACTATATTGTGATGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATACATACATACATACATACATACATAAATACATATATATATATATATAAATACATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAAATACATATATATATATATATCAGGATCTTAAATGACTTATCATGATTTAATACTTGGGCACATCGTGCAGCTCTTTAATAGCCTTTGCACTGACATTTGAGCATGTACTGGAAAGTGTTTGTGTTTCCTCAGTTAAGATCCTGGAGAAGCGCCACATAATGAAGGAGAATAAAGCGCAGTATGTCAAGAGAGAACGAGACATAATGTCACACCTGGATCATCCGTTCTTCGTCAAACTCTACTTCACCTTTCAGGACGAGGAGAAGCTGTG[T/A]ATCCTTCACACAAACTCTGATGCTCAACTAGTATGGGTTGCACAGCGTCAATATTAAGGAGCACAATAAAGATGGCTGTTGTGTTTCTTTCAAATGAGCTAATATGACATGGACATGCTTATTTTTGTGGCATTTTTTACACTAAAAATACATGTTTTTAATTATTTTGAGCACATTTTAGGTAGCTTGACGTTTATCATTAGGTTTGTATGGTATGCCGTTTATTGAACTATCCCTTTAAGATGTTACTCAAGATATATCTATTAATGGCATATTAGGCTTCTCCTAATTTCTTTCAGCACTATACATGTATACATGTCAGCATATGTTAATGAAGGATTTGTCAAAGCCTTGCTTATGTCAACGCTGCATTTTATAGCTTGTTTTCCTGAATGTCGTGTCAGATTTTGGATTAAGCTACGCTAAAAATGGCGAATTGCTGAAATACATTCGAAAAATCGGCTCATTTGATGAGACCTGCACACGCTTTTACTCTGCTG
Associated Phenotype:
Not determined