Busch Lab

ZMP

cand1

Ensembl ID:
ENSDARG00000017841
ZFIN ID:
ZDB-GENE-040426-2872
Description:
cullin-associated NEDD8-dissociated protein 1 [Source:RefSeq peptide;Acc:NP_998650]
Human Orthologue:
CAND1
Human Description:
cullin-associated and neddylation-dissociated 1 [Source:HGNC Symbol;Acc:30688]
Mouse Orthologue:
Cand1
Mouse Description:
cullin associated and neddylation disassociated 1 Gene [Source:MGI Symbol;Acc:MGI:1261820]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa40252 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa20236 Essential Splice Site Available for shipment Available now
sa40253 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa40252
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003694 Essential Splice Site 123 1230 3 15
Genomic Location (Zv9):
Chromosome 4 (position 12479570)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 13416197
GRCz11 4 13415046
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCATTGGCCTCAAGACAGTGATTGGGGAGCTCCCACCAGCTTCCAGTGG[T/G]AAAACATCCTTTTCCTGCTTGTATTAATGCAGATGTCTCAAAATATTCCA
Long Flanking Sequence:
AATGCTTTAATGCGAAATTGATTCATGCCGCAGTGATTTATTGAGAAGTATAGTTGCTTTTTACAATGAGCTATCTTGGTTGTTAGCCTCTATTCATTCCCTAGATAGTCCTGAAAGGATTGCATGAAGAAGTCACTGCAATCTCTCTTCATTTCAGTGTGTTAATTTGCTGAAAAACGTTTTTGCTGAGCATACTTGGAATATCGCTGACTAGAATGCTAAGCATAAGTAATTTTGTAGTAGATATTATTGCAAGGAATCTACATTTACGACCTTGCATAGCAAAAAGATAAATGGTAGGTAATTCAAAAGGTTACACTAAAATCCTTGTTTTTTTTTTGCAGTTTGGGACCACTTGTCAGCAAAGTGAAGGAGTACCAGGTCGAAACGATTGTTGATACATTGTGTACAAACATGTTATCAGATAAAGAGCAGCTTCGAGATATTTCCAGCATTGGCCTCAAGACAGTGATTGGGGAGCTCCCACCAGCTTCCAGTGG[T/G]AAAACATCCTTTTCCTGCTTGTATTAATGCAGATGTCTCAAAATATTCCACAATTTTTTCCACTCTATTCTGTGCTGAAAGGATGGAGATTTCATTCACACGTGCATGGCTATATTTAGTCATTTTCATGAGCCATCTTGCCTGCTAAATCAGTTTCTCTTTGCTTTAGGCTCTGCTCTTGCTGCTAGCGTTTGCAAAAAGATAACAGGCCGCCTTACAAGTGCCATTGCCAAGCAGGAGGATGTCTCGGTTCAGCTGGAAGCATTGGACATCATGGCAGACATGCTGTGCAGGTATGTCAGATGAGGCATGTGATGACTGCTGCTTTTGTTTCAACCAATTCTTCTATTGAGTGCACAAGGACTCCTGCGAAGTAATTTCTAGATGCGTTTGTGCACATTCATCACACCAGTGACAGTTCTCAGTCTTTTACTTCAGTTCACTGATCTTAATGTACTTTAAGGTCTTTCAGTTTAGATGCTGACTCTCAGCTCTGTTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20236
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003694 Essential Splice Site 164 1230 4 15
Genomic Location (Zv9):
Chromosome 4 (position 12479864)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 13416491
GRCz11 4 13415340
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCTCGGTTCAGCTGGAAGCATTGGACATCATGGCAGACATGCTGTGCAG[G/A]TATGTCAGATGAGGCATGTGATGACTGCTGCTTTTGTTTCAACCAATTCT
Long Flanking Sequence:
TGGTAGGTAATTCAAAAGGTTACACTAAAATCCTTGTTTTTTTTTTGCAGTTTGGGACCACTTGTCAGCAAAGTGAAGGAGTACCAGGTCGAAACGATTGTTGATACATTGTGTACAAACATGTTATCAGATAAAGAGCAGCTTCGAGATATTTCCAGCATTGGCCTCAAGACAGTGATTGGGGAGCTCCCACCAGCTTCCAGTGGTAAAACATCCTTTTCCTGCTTGTATTAATGCAGATGTCTCAAAATATTCCACAATTTTTTCCACTCTATTCTGTGCTGAAAGGATGGAGATTTCATTCACACGTGCATGGCTATATTTAGTCATTTTCATGAGCCATCTTGCCTGCTAAATCAGTTTCTCTTTGCTTTAGGCTCTGCTCTTGCTGCTAGCGTTTGCAAAAAGATAACAGGCCGCCTTACAAGTGCCATTGCCAAGCAGGAGGATGTCTCGGTTCAGCTGGAAGCATTGGACATCATGGCAGACATGCTGTGCAG[G/A]TATGTCAGATGAGGCATGTGATGACTGCTGCTTTTGTTTCAACCAATTCTTCTATTGAGTGCACAAGGACTCCTGCGAAGTAATTTCTAGATGCGTTTGTGCACATTCATCACACCAGTGACAGTTCTCAGTCTTTTACTTCAGTTCACTGATCTTAATGTACTTTAAGGTCTTTCAGTTTAGATGCTGACTCTCAGCTCTGTTGTGCAGTAACTAATGGCAGACTTGGGTGAATGCATTTTGCATTCATATTTACATTCGCGCATTAGCCAGATGCTTTTATTCAAAGCGACTTGGAGATTTTGCCAACTTGTGTGTTCCCTGGGAATTAAATCCACAGCTGTGGCATTTCTAAAGTTCATGCTTTATCAGTTGAGCTACACAGAACTATCTAAACAATATTTTCCCTTAAGGTGGATTTAAGCCTTTCACACTAAGAATAAAACTAATGATAATAACAGTGATATGTTCATTTTAACATTACAGTTACTTGTGTGATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40253
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003694 Nonsense 348 1230 8 15
Genomic Location (Zv9):
Chromosome 4 (position 12484150)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 13420777
GRCz11 4 13419626
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCAAACAGGAAGTGATGATGAGTACAGTGATGATGACGACATGAGCTGG[A/T]AAGTGAGGAGAGCGGCAGCAAAGTGCTTGGATGCAGTGGTGAGCACACGA
Long Flanking Sequence:
GCTGCCTTCATGACTGCTGTTTCTCTTCCTGATCTTGAAGTTTTTTTTTATTTTTGTCCCCTCTTGGAATGTTGTTTTCATCCATAAATCATATTCTTACCTATTCGTTGTTTTCTTTTCAATAATTGATTGTGCTGACTGTGCACTAGCTTGTAAGCAGCCTTAGGAGGCTGGTACAGCTTGGCAGCAGATTTGAGAGAACATTTGTTTTTCTCAGAAGTCTGTTTCAGTGTTGATGAAGAAGAAGTTTTAAAGGACAAACTTGTTGCTCTGTGTCTTCAACACTGTCTGATTGTTGACAAAGAAATTCTTTTTTAGCTATCTTGGAACTGATGTACCCAGAATCATCTTCCAAAATAAAATGTGAACGCTGTATTTCAGCAGTTGCAAGTGCAATGGATAGGAGAATTCATATTGGCATCTGTGATTGATATAATCTAATCATTGTGATCCAAACAGGAAGTGATGATGAGTACAGTGATGATGACGACATGAGCTGG[A/T]AAGTGAGGAGAGCGGCAGCAAAGTGCTTGGATGCAGTGGTGAGCACACGACATGAGATGTTACCCGAGTTCTACCGCACTGTTTCTCCAGCGCTCATTGCCCGCTTTAAAGAGCGGGAAGAAAACGTGAAGGCGGATGTGTTCCATGCGTACTTGTCCCTACTCAAGCAGACGCGTCCTGCCCAGAGTTGGCTCTGTGACCCAGATGCCATGGAACAAGGAGAAACACCTCTCACTATGCTTCAAAGCCAGGTGTGGGAAAAATGCTCTTTAAAAAAAAAAAAGAACTGCTAGTTTATTCTAAGAACCTGCTCAACAATACTGTAAAGATAGCCAGAAATTGAAGTTTTAGGTTAAAATTACAGTACTGATTGGTACAGAAGTCGATACTTTGGACATTCCGATCAGTCATGTTTTAAGATAGACTGTATTACTAGTCCATACACTTGGGCCTCCCGATTATCTGAATTTATTTCTAAATGTGATTGTGCTGTGTGAATT
Associated Phenotype:
Not determined