Busch Lab

ZMP

Q7ZUX0_DANRE

Ensembl ID:
ENSDARG00000017834
Description:
Zgc:55983 [Source:UniProtKB/TrEMBL;Acc:Q7ZUX0]
Human Orthologue:
MICAL1
Human Description:
microtubule associated monoxygenase, calponin and LIM domain containing 1 [Source:HGNC Symbol;Acc:20
Mouse Orthologue:
Mical1
Mouse Description:
microtubule associated monoxygenase, calponin and LIM domain containing 1 Gene [Source:MGI Symbol;Ac

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa7303 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa31192 Nonsense Available for shipment Available now
sa38246 Nonsense Mutation detected in F1 DNA Not yet available
sa39551 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa7303
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008682 Essential Splice Site None 562 1 19
ENSDART00000132952 None None 448 None 15
ENSDART00000137821 None None 702 None 16

The following transcripts of ENSDARG00000017834 do not overlap with this mutation:

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8562130)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8801935
GRCz11 1 9486046
KASP Assay ID:
554-4901.1 (used for ordering genotyping assays)
KASP Sequence:
TCTCAGGAGTTTCAGGGATTTCTTAACTGCAGCTGACGGTGAAATTAGTG[G/A]TGAGTGTTTGTGTGTGTGAGAGATTAAGCAAAAWTCCTTCAGCATTCAGC
Long Flanking Sequence:
ATTTTTCAAGATAACCGATGACACTGTCGTTGAACAAAAACATTATATAATAAATTAGTAACTTAAGTGTTTAGTAAATAAATATCATTTTACAGTTTAAAAGACTGTTTCACCCACATAAGTATAAATCAATATAAACCATGACTAACAGAATATTTAGGGAATATATTGAAGGAACAACAACATTCCATTTACTTAAAAACTGTTCAATAGTACGAGATGTTTTCAGAGCTTTTATGTTAAAGAATGATTAATGTAGATCAGAAGCTAATATTTAGACATCATCCAACTCCCTTTTTCAGAAATAGGAGAATGAGAAAAAAAGCACGTGACTGGTTTGAAAGTAGCATGATATCACCATCTGCTATCATCATATGCCTTGAGTGAGGGAAGTGTTTAAAACTCCCTCACCTTAAACTCCACCCATGAACAAGACGTCATAACGCTTCTTCTCAGGAGTTTCAGGGATTTCTTAACTGCAGCTGACGGTGAAATTAGTG[G/A]TGAGTGTTTGTGTGTGTGAGAGATTAAGCAAAAATCCTTCAGCATTCAGCGTTCCTGACCGTCTTCACCACTTCGGAAAGAGGATATTTCAGCTTCCCAGTCAGTAGTCGTCCGTGGTTGAATCGCATTTGCACCATGGCTGCTGTGAAAGCGCTTCAACAGTGGTGCAAGATCCAGTGTGAAGGATACCGGGACGTGTCGATAACCAACATGACCACATCTTTCCGGGACGGTTTGGCTTTCTGCGCTCTAATTCACAAACACAGACCGGACTTGATGTAAGTATTAGCAGCAGCTCCCCCGTAAAACAACGCGCGGTTTGGCGTTGCATCGTATTCAGAAAACACACCGCTTCTGGACGCTTGACGTGAAATTAAATGTTTCACATTCAAACGAATAGTTTGATTATAGTTTATAACTCTCCTCAGGAGCGCTGAACTGGCTCAAAACAAACTACACTTTTGACGAGGACGTTGTATCTTGTTATGCAGTAAAAGTTT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa7895
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008682 Nonsense 67 562 4 19
ENSDART00000132952 None None 448 None 15
ENSDART00000137821 None None 702 None 16

The following transcripts of ENSDARG00000017834 do not overlap with this mutation:

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8555218)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8795023
GRCz11 1 9479134
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGTTATTGCTGAGTGCTTTTTTTTCTTTCTTTTTTTAAACCAGGCTTTC[G/T]AAGTGGCAGAGAAGGAGTTGGGAATACCTGCCCTCCTGGATGCTGAAGAC
Long Flanking Sequence:
TAAATTAATGCATACATTTGATTCACTGAAGCAAGTATTACCCCCCTGAAAATCAATGTATAATTCACACCCTAGTTATAAACTATCCTTAAACTAATGCAGCCCTACAAAATACAAAGTGAAAAGAATTGGTTTCAGTAGCTAATGTAAATCAATATGTTATGTGTAACATTTTTAATCGTAAAATGCCCATAAGTGGAAATGGTCAAGGAAGTAGACAGTTATTTTACAGGTTAAATATTTATCAGGATTTTGTATTTCTCAAGTGCTTCCCCTTCCCTTTTTAGAGCATGTGTTTTTGCGGATCTGGAACTTGATAATGGAGGTATATTAATATGTAAAATTGTCAATAGGAAATCCTGTGATTGTTCTGCTTCACAGAAAATCGTGCACACACACACACACACACACACACACACACACACACACACGTACACACACACGTAAACCCTGTTATTGCTGAGTGCTTTTTTTTCTTTCTTTTTTTAAACCAGGCTTTC[G/T]AAGTGGCAGAGAAGGAGTTGGGAATACCTGCCCTCCTGGATGCTGAAGACATGGTGGCTTTAAAAGTGCCAGATCGCCTTAGTATTCTGACTTATGTGTCCCAGTACTACAATTATTTCCACGGGCGCTCTCCCAGTAAGGCACACATTTCAATGCTGTTACTACTGCATATAGCTGTTATTTAGCCAATTAACAGGAGTCATTTTAAGACGTACACAATTCCAGATCATAAAACTAAGGCTGCTTATAGACTGAAATGTTTTAGAAGTGACAACCACTTTTAAGTGCAGCAGGAGTGAATATATTATCTTTTTAAAAGTTTGAAAGGGAATGTGACTGGTTCCTGAAAGTATGATTGACCCATTGGTGGGAATCATAGCAACTTTCTGGCTTCTCTCTTGTTTGGTTTCCTATATGTTTGATATTGGTAATATTGTGGTGACTAAAGATGTCAACATATGCATGTTTGTGTTGGAAAGCTGCAGTGTGGAGTGCGCTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31192
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008682 Nonsense 512 562 9 19
ENSDART00000132952 Nonsense 398 448 5 15
ENSDART00000137821 Nonsense 401 702 5 16

The following transcripts of ENSDARG00000017834 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8548092)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8787897
GRCz11 1 9472008
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAGAAGAGCTTATCCAGGAATGTGAACACACCGTCATCTAACAGCAAG[G/T]GTGAGGAACACTGACTTACCTGTGCTTTTACTGTACATGCACTGATGTCT
Long Flanking Sequence:
TTTTGAGGAAAACCAACAGAAATTGGATTAAAGTAATGCTTTCTAGTCTGCATGTATTGAGCGTGTTTGTGCTACTTTATAAAGACTGTCTGCTTTCAAATTGTTGAATTCAGTAGCGTACACATTAAACTGAAGTATACTTTTGGTTTTTGAGCACATTATGTAATTATCATTTATGTCTTCACTTGTTTTCTTAGGGTGGAGGTGTACAAGGGTCACAATGAAACAGAATTATAGCCTTTATGTACCTGTCGAGTTTTGTTTGAATACTTGGTGTTTGCTGACATGTCGGCTCACAAGACACATTCATCATGAACACAATCTCCTTTCACAGTAATGTTCCCCCTCTGGAATCTAATGCTAAAGCCCCCTTTGGTCGGGTGCGTCTCAAAGCGCTTGAAGCCAGTGGTGAAACTACTGCTCCTGCCACTACAGTCCCATCCTGGATGAAAGAGAAGAGCTTATCCAGGAATGTGAACACACCGTCATCTAACAGCAAG[G/T]GTGAGGAACACTGACTTACCTGTGCTTTTACTGTACATGCACTGATGTCTAATATACAGTGGTTGTTTTCATTGGCAGAGATGGTTTGTTTTGATTGATTGGATATACTAATGTTGCGCATTTAATGTTTTGATATGTTTATATAACTTATTTTAATTAGACTTTTTATTTATTTTAATTTAATTAAAGACTGCTTTTATTATTATTATTATTATTATTAATAATAATAATAAAGATGATTATGATTGTTGTTCTTAAAAGCTCAGTGTCAACCAATTTTTTGGACTCGAATGCAGTTCAAAGACCAACAAAAAATAATTTATATTCATTATTATTATTATCATTATTATTAATATTATTATTATTATTACTACGACTACTATTACTACGACTATTACTACTGCTATTCTATTATTACTATTACTACAACTACTGTTATGACTACTAATACTATTGCTTATATGACTATTACTACTGCTGTTACTACTATTACTATGATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38246
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008682 None None 562 15 19
ENSDART00000132952 None None 448 11 15
ENSDART00000137821 Nonsense 596 702 12 16

The following transcripts of ENSDARG00000017834 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8542131)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8781936
GRCz11 1 9466047
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCATCAGAAACAAGCAGGTCTACATGAGACGGGAGTCTGAGCTTGTTTA[T/A]ATGTAAGAGTGCATAATCTCTCTGCATTGCTGCGTTAATGTTGACTCCTC
Long Flanking Sequence:
CACTGTTGTTCTAAATATGCATGACACACTATTTATTTTTCTTTTGGTCTAGAAACTTAGAAACTAGGAATGGCATTTATGAATGTTGTCTTGTTTTAATGCTTAATAATTCCTCCTTTGACCTAACTTTTTTTTAAATAAAAAGGTTTTTTAAATTGTAATTGCTATTTCAGTTTTACTACAGCACTATTTCATTAAATTACCCACACGTCCTTCAAACATGCTTATTAAAACTGTCCTCCAGAGACCTGATGTGGTCCTTTGGATCTCCAGCAGATGGGGACAAATATTAGAAATGTAGATTCTCAACTCCTTTTTATTTGAAGTGGGAAAAAAGTGAAAAGATAATGAAAGTATAAGCCAATATTGCATTTCATTGTTTTATTATTGGTATTTTCAGATGGAGAAGAGGACGCATTAATGAATGACTTAATGGTGGACTGGTTTACCCTCATCAGAAACAAGCAGGTCTACATGAGACGGGAGTCTGAGCTTGTTTA[T/A]ATGTAAGAGTGCATAATCTCTCTGCATTGCTGCGTTAATGTTGACTCCTCAGTATTCAAGACTTCTTCTTTGTGTTGTTTTTTTTCTGTGATTGGGCTATGATAGTGCCAGGACGCAGGATCTTGAGGAAGAGCAGCCCAGTGTTGATGCCGAACTCCGGAGACTTATGGAGAAACCAGGTTAGCATCACACTGAACAAGTCTATCTTTTTTTTGTTTGCATTAAGCAACAAAAAAATAAATGCGGTTTGCATTTTTTTTTCTGTTTCTGAGCTTCTTCTAAAAAAAAATTATAAATAGGCAAACGATTGGCAGTTTTCTTTCTGGGTGGAGCTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTAAAAGATCAAATGATTTCTAGAACTCTTGAGCAGCCTAGGGCGAAAAATCACATCCTGACCCGAAACATTTACAGACCATTTACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39551
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008682 None None 562 19 19
ENSDART00000132952 None None 448 15 15
ENSDART00000137821 Nonsense 691 702 16 16

The following transcripts of ENSDARG00000017834 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 8537032)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 8776837
GRCz11 1 9460948
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGATATGAAGAAGGAAAAGGTCAAGAAGATGTCTCCAGTAACTCGATG[G/A]TTTAGCATGAGAAAACGGAGGTCTTCAGAAGATTGATCGTCTTGTAGTTT
Long Flanking Sequence:
TGAAGTACTTTACTTATTCTAGGAGGAGGAATATAACACAAGATCTGTTAACCAAATGCTAGAAAGCTAAGAGTTTGTTTTAATACAGGGTGCAAAATGAAGATATTTTGAAGAATGTTGGAGACTGGTAGCCATTTTCTTTGTGTTGTTTTTTCTTACAATAGTTTCTGGCATTCTTCAAATTATCTTCATTTAGGTTTTACATAAAATGCTAGAAGGCTGAGTTTTTTAATGTAAAACCTAAATGAAGATATTTTAAAGAATGTTCAAGACCCATAGCCATTCTCTTCCATAGTGGTTTTTTCTTATTATGGTTTCCAGCATTCTTTAAATTATCTTCATTTGTGCTCGAGAAGGAAAAAAAGATTGTAAATGTTTGGAACTACATGAGAGTAAATGCTTATTTTTGAGTGAACTGTCTCTTTAAGTTTGTATTATGTTTTACCATTTGCAGATATGAAGAAGGAAAAGGTCAAGAAGATGTCTCCAGTAACTCGATG[G/A]TTTAGCATGAGAAAACGGAGGTCTTCAGAAGATTGATCGTCTTGTAGTTTTTGTTTTTGTGTGTCTTCCAGAACAATGTTTCTGCCACAGTTTGAGGTCAGATCTCAAAATATAAACTGCAGTCACACGCTCTTCAAAACATGGTGTTTTTGTGAAATGCCATCATTACTCATTTTCACACTCTTCATTTCACATACGTTTGCACTTGTTTTGTTGTTCAGACCTCTGTCTGTTGTCTTTATGGGTGTGATTTTTGTCATTTGTTAGCAAACGCTTTTGCACTTGAATCTTCTGAATAATGTCTCTCAGTCAGTGTTCCATTAGGGAGTTGGACAGTGTCGAGAGAGAGTCTTACTGATTCACATTGGATCAATGCTGAAAATGGACAGGTTGAGGTCTGATCTCAAATATATTCTAATACAGAGAATTGACTTTTTATTATAAATGTTTTTGTAAATAGAAACAATCATATTTTAGCGCTTTTAAAAGGCATCGTTTTA
Associated Phenotype:
Not determined