Busch Lab

ZMP

mmp2

Ensembl ID:
ENSDARG00000017676
ZFIN ID:
ZDB-GENE-030131-9123
Description:
72 kDa type IV collagenase [Source:RefSeq peptide;Acc:NP_932333]
Human Orthologue:
MMP2
Human Description:
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) [Source:HGNC S
Mouse Orthologue:
Mmp2
Mouse Description:
matrix metallopeptidase 2 Gene [Source:MGI Symbol;Acc:MGI:97009]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa45285 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa34122 Nonsense Available for shipment Available now
sa1218 Nonsense Available for shipment Available now
sa21006 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa45285
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026712 Essential Splice Site 394 657 7 13
Genomic Location (Zv9):
Chromosome 7 (position 36877367)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 35151210
GRCz11 7 35422687
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCAAAAGCTTTGACGATGACCGCAAATGGGGCTTTTGTCCTGATCAAGG[T/C]GATGCAAAAATATTTTTTGATTCTTGTGTGTGATAGTTTGTATAATTTCA
Long Flanking Sequence:
GGTGACTATAGGTAACTAGACAAGGAAAAACTTAGTCCCCAATACCTTATGCCTAAGCTAACCAACTGGTAGTTGATGTAGGAGCAATGTGAACAGCAATAGTAAACAGAATGTCTAAAGAGGAATGTTTAAAAGTGCTTATATGTGATTATATTTCATCAAAGTCATATAAATTACTCTATTTTTATTTCAAACCAATATCTCAAATATCCCAAAAACTTTCCAAAGGCTTCATCCATAAGCTTTTCTAATGATTATTTTGTCATTGCTAACATTTAGGTGTTTTTTTTTTTTAATTCATGAATTGTATTTTTTTTTTGCACAGCAATGTCAACATCAGGAGGAAATTCAGATGGAGCACCCTGTGTCTTCCCCTTCAAATTCTTGGGTGATAGTTACGACTCCTGCACCACATCAGGGCGCAATGATGGAAAAATGTGGTGTGCTGTCACCAAAAGCTTTGACGATGACCGCAAATGGGGCTTTTGTCCTGATCAAGG[T/C]GATGCAAAAATATTTTTTGATTCTTGTGTGTGATAGTTTGTATAATTTCAAGCTCGACAAGATTATTCTGTTCTTTAATGGGATACAAAAGCATTTTTACCCACTTCCTGTCACTGTCTCTTCCTTTTCCATGGAATATGATCCTATATGCTTTTTTATGTAGCTTAAATCATTTTAAAAAATCAGCATCTGTTTTATTTTCAGGTTACAGTCTATTCCTTGTGGCGGCCCATGAGTTCGGCCATGCCCTGGGTTTAGAGCATTCTGATGACCCCGGAGCTCTCATGGCTCCTATCTACACATTCACCAAAACCTTAAGACTGTCTGATGATGATGTTAAAGGCATCCAGGAGCTCTATGGTAAGTGTGACATGAAGATGATTTATATCTATGGAAATCATTTGTTTCTCTTGATTTAAAACACTGTACATAGTAAATAATTACATAGCTATGTTTTAAGTAAATCCATTTTCCCCCTGCAAAGTACTGATTTTTTTTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34122
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026712 Nonsense 481 657 9 13
Genomic Location (Zv9):
Chromosome 7 (position 36876403)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 35150246
GRCz11 7 35421723
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTATGTAATGAAAACATCATATTTGATGCTGTAGCCCAGATCAGAGGA[G/T]AGATCTTCTTCTTTAAGGACAGGTAATACATTTCATTCATTCTTTTTTTT
Long Flanking Sequence:
ATCCATTTTCCCCCTGCAAAGTACTGATTTTTTTTCTACATTTCAATTAGAAATGCTAATGCTTGGAGCAAAAAAATGCCAAATAGTCAAAACAAAAAATATGCCATAATTTTAAATATGTTTATATTGACTTTTAGACACAATACCAATGATTAAAATGCTGTTTTCTGCAAAGAAAAAAAGAGAAATGCTCATAATATTTGTATTTTAAATCAGAAAAAGAAATGCTATCAGACTGTTATTAAAAACAACAAATTCCTAGAAAATTTACAGAAACTGAGAGCTTTCAAGTGGTCATTTAAATGTCCCATTCAGTATTGATTAATTCTGATGTTGCATTGATTATAATCATATTTAAAATTCTTTGACTTCTTTACTCTTCTTTTCTCTGTACAGGAGAACCAACAGACAAGCCATTGCCCACTCACACCCCACCAGTCACACCAATGGATGTATGTAATGAAAACATCATATTTGATGCTGTAGCCCAGATCAGAGGA[G/T]AGATCTTCTTCTTTAAGGACAGGTAATACATTTCATTCATTCTTTTTTTTTCAGTTTAGTCCCTTTAATAATCAGGGGTCGCCACAGCGGAATTAATTGCCAACTTATTCAGCATATGTTTTACTCAGCTTGTGTCCTTCCAGCAGCAACCCATCACTGGGAAATACCCATACACTATTGCATTCACACACATACACCACAGCCAATTTAGCTTATTCAATTCATCTATAGTGCATGTCTTTGAACTGTGGGGGAAACCAGAGGACCCAGAGGAAACCCAAGCAAACGCAGGGAGAACATGCAAACTCTACACAGAAATGCCAACTGACCCAGCTGGGATTCGAACCAGCGATCTTTTTGCTGTGAGATGACAGCGCTACTCACTGCGCCACTGAGTCACCGGCACTCATTTTAAAGAATTATATTTTTTACTATAAACACATTTTCAAGAAAATAATAGAGCAATCATCTATTTGTATATTCACGCAAGATTACAACAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1218
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026712 Nonsense 630 657 13 13
Genomic Location (Zv9):
Chromosome 7 (position 36865663)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 35139506
GRCz11 7 35410983
KASP Assay ID:
554-1127.1 (used for ordering genotyping assays)
KASP Sequence:
TATGTGGTATTAACACGTATGAACTGTTTTTAGGTCACAGCTACTTCTTC[A/T]AAGACTCACACTATCTCAAAATGGATGACAGCACTCTGAAAATTATCAAA
Long Flanking Sequence:
CAGACAGTCACATGGCAGCAACTCAACACATTTAGGCATGTAGACATCGTCAGGTTGATCTGCTGCAGTTCAAACTAAGCATCAGAATGGGGAAGAAAGGTGATTTAAGGGACTTTGAACATGATATGGTTGTTGGTGTCAGATGGGCTGGTCTGAGTATTTCATAAGCTGCTGATCTACTTGGGTTTTCATGCACAACAATCTCTAGGGTTTACAAAGAATGGCCTGAAAAAGAAAAATATCCAGTGAGCAGCAGTTCTGTGGGAGCAAATGCCCTTTTGATGCCAGCGGTCAGAGAAGAATGGCCAGACTGGTTCAAGCTGATAGAAAGGCAACAGCAACAGTATTTAAAAAATGTCATATTTAAAAAAGATTCACACTTTAATATTTTTTAAAAAATCCCCTAAACCTCTGTACAGGTTTATGTGTTTTCATTGATGTTGAAGTTTTTATGTGGTATTAACACGTATGAACTGTTTTTAGGTCACAGCTACTTCTTC[A/T]AAGACTCACACTATCTCAAAATGGATGACAGCACTCTGAAAATTATCAAAGTCGGCGAGGTCAAAAAGGACTGGCTGCGCTGCTGAACATCGACAGACCATTCAGCTCTATGCCCTTCAACACTCAATAAAAATGGCCAGAAATGACAGCACTCAAATTTACCATTCAGCCCCTCTTGGTTAGTCAGAGCCTCTTAGATTATAACCCTTTTTTACTAACCAGAGAGGCCTGGTAAGCTTCACTGCCTGGACCCACAGTAAGCAAACAGGACTGTCATTTTAAATGTTTTGTTGTAATGTGCGATATTTTTCTTTATTTTTAAATATGAAAGGGTTTAGTGCACTCCTTACTATAACCTTACATGTATATCATCAGACTTAAAAAGGCTTCTGACATTTCTCACGTACATGTAAAGTGTGTCAGTGAGATATATCTCCTTTTTTTATTTGCACAGAATAACTGAATCCAGGCAGTATGTAAAAAAGCACAATGTAATGTTT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa21006
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026712 Nonsense 654 657 13 13
Genomic Location (Zv9):
Chromosome 7 (position 36865589)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 35139432
GRCz11 7 35410909
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGACAGCACTCTGAAAATTATCAAAGTCGGCGAGGTCAAAAAGGACTG[G/A]CTGCGCTGCTGAACATCGACAGACCATTCAGCTCTATGCCCTTCAACACT
Long Flanking Sequence:
CTAAGCATCAGAATGGGGAAGAAAGGTGATTTAAGGGACTTTGAACATGATATGGTTGTTGGTGTCAGATGGGCTGGTCTGAGTATTTCATAAGCTGCTGATCTACTTGGGTTTTCATGCACAACAATCTCTAGGGTTTACAAAGAATGGCCTGAAAAAGAAAAATATCCAGTGAGCAGCAGTTCTGTGGGAGCAAATGCCCTTTTGATGCCAGCGGTCAGAGAAGAATGGCCAGACTGGTTCAAGCTGATAGAAAGGCAACAGCAACAGTATTTAAAAAATGTCATATTTAAAAAAGATTCACACTTTAATATTTTTTAAAAAATCCCCTAAACCTCTGTACAGGTTTATGTGTTTTCATTGATGTTGAAGTTTTTATGTGGTATTAACACGTATGAACTGTTTTTAGGTCACAGCTACTTCTTCAAAGACTCACACTATCTCAAAATGGATGACAGCACTCTGAAAATTATCAAAGTCGGCGAGGTCAAAAAGGACTG[G/A]CTGCGCTGCTGAACATCGACAGACCATTCAGCTCTATGCCCTTCAACACTCAATAAAAATGGCCAGAAATGACAGCACTCAAATTTACCATTCAGCCCCTCTTGGTTAGTCAGAGCCTCTTAGATTATAACCCTTTTTTACTAACCAGAGAGGCCTGGTAAGCTTCACTGCCTGGACCCACAGTAAGCAAACAGGACTGTCATTTTAAATGTTTTGTTGTAATGTGCGATATTTTTCTTTATTTTTAAATATGAAAGGGTTTAGTGCACTCCTTACTATAACCTTACATGTATATCATCAGACTTAAAAAGGCTTCTGACATTTCTCACGTACATGTAAAGTGTGTCAGTGAGATATATCTCCTTTTTTTATTTGCACAGAATAACTGAATCCAGGCAGTATGTAAAAAAGCACAATGTAATGTTTTGCTAGTACTGATATGAAAAAGATTAGGGACTTAATTCATGTTCTATTTCGTAGTAAATACTATCCAATAAACA
Associated Phenotype:
Not determined