ZMP
braf
Ensembl ID:
ZFIN ID:
Description:
serine/threonine-protein kinase B-raf [Source:RefSeq peptide;Acc:NP_991307]
Human Orthologue:
BRAF
Human Description:
v-raf murine sarcoma viral oncogene homolog B1 [Source:HGNC Symbol;Acc:1097]
Mouse Orthologue:
Braf
Mouse Description:
Braf transforming gene Gene [Source:MGI Symbol;Acc:MGI:88190]
Alleles
There are 7 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20232 | Essential Splice Site | Available for shipment | Available now |
| sa33418 | Nonsense | Available for shipment | Available now |
| sa33417 | Nonsense | Available for shipment | Available now |
| sa20231 | Essential Splice Site | Available for shipment | Available now |
| sa40247 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa20230 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa20232
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000023894 | Essential Splice Site | 390 | 777 | 8 | 19 |
| ENSDART00000048391 | Essential Splice Site | 390 | 817 | 8 | 20 |
| ENSDART00000131168 | Essential Splice Site | None | 358 | 15 | 26 |
| ENSDART00000132650 | Essential Splice Site | 390 | 575 | 8 | 13 |
Genomic Location (Zv9):
Chromosome 4 (position 11150015)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 12086642 |
| GRCz11 | 4 | 12085491 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCAGCCCCTAACGTCCATATCAACACCATTGAGCCGGTCAACATTGAT[G/T]TGAGAATGATATTTTAGTCAAAAGGATTTAATCCCTTTTGAATAGGTGGA
Long Flanking Sequence:
AACCTGTGTTAGGCACACTTCATAAATGCACAATGTGTTTTTTTGAGAAGTGATTGTAAGATAGTGTTTAGTGCAAGTGTTGGTTAAAATGTCAGAAATATGAATGACTATATTTCTACAGATGGTTTGTCAAGCACAGTTACCTGTGTAAGCCATTTATTTATTTGAATAATTTAAATTCCAGCATGATCAAATTTAGCTCTGCCCCCTACTTGGCTTGCTTTACACAATTTGGCCCTTGGGAAAAAAGTAATTGGGGTTTAGGCTTAGTATTGGAACCAAAATTGTATCGTAAACAAACAAACTATGCAAAATGTCATTGTGTCTCTGTTTTCTGCAGCTCTCTGTGCCATCCTACTGTGTCCCCGTCCAAATCCATCCCTATCCCGCAATCTTTTAGACCTGGAGAAGAGGACCACCGTAACCAGTTTGGTCAGAGGGATCGCTCCTCATCAGCCCCTAACGTCCATATCAACACCATTGAGCCGGTCAACATTGAT[G/T]TGAGAATGATATTTTAGTCAAAAGGATTTAATCCCTTTTGAATAGGTGGACTTTTCTTTTATAAATAGTTTCAGAAAAATTAATACTGTAAGTATTTGAGGTGTGCTCTTATTTCATTACTTTATTAATATTAACTATATAAGATACTTTTGTAGTACCCTAAACCAAAAGGCACCAAATCTCCCCTTAGTGCTTGCTAATCTGTGTTATTTCCATCCAGGATTTGATTCGTGATCAAGGCTTACCGAGGTCAGATGGAGGTAAGGGTTTTACGAAACATACACTGAGACACACTGAATTCAAATGGCTTTCCGTCATCCCATGTCTTTGTGCTATCTCTGTGTCATTGGCCTTAGAAGTTTGGGACAGCTGATCCATTTCACTCTGCCTGCTATTAGAGCCGACAAACAGGCTTTTTTCTCCCCTGTCCGCTTTGTGAAGTGCTTCTGCCCTTTTCTTTATCACTAGCGGCCTGCTGTAAACTACTAAATCCTAATCAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33418
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000023894 | None | None | 777 | None | 19 |
| ENSDART00000048391 | Nonsense | 417 | 817 | 10 | 20 |
| ENSDART00000131168 | None | None | 358 | None | 26 |
| ENSDART00000132650 | None | None | 575 | None | 13 |
Genomic Location (Zv9):
Chromosome 4 (position 11147798)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 12084425 |
| GRCz11 | 4 | 12083274 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCCCCCTGCAGCCCCCTCGCAACACCCAGCCCGCTGCTTGAGGAAGAAC[C/T]GAACACGGACCTCAAGCCCCCTTCTGTCCTCCCACCCCAATGACATTGTC
Long Flanking Sequence:
TGCACTTGGTCACAATAGGGAATAAAATAGAACTTCTACTGTAATAAGATTTTCAAATTTGGCCCACATTAGCTTTGTTTACATATAAAGGGTGGGGTTTATGACATATACTGCAGAAAGCCACCAGGGGGTGATCAAAATATTCTGGCTTCACTTTTTAAGACTTTCAAGGTCACACCAGTAAAAAAAAGACTGTTAAACCTACAGTTTCATGCCTTCAAAATAAACACGTTCATATAAAAGCAACAGATCAACACAATGGTGAATAAATGATAACCGAACAATACTTTTTGGCTGAACTATCCTTATAAGGACAGACTGGCTCTGTGTCACCTAGAATCCACTTAATGATCTGTAAACAATGTCTGAGAGTAGACACAGGATTTTTGGTAGTGGGTAACTGGAGGTGCACCTGAGCTTCAGGGGCCAGTGATCCCGTGTCTGTCTCTCTCCCCCCTGCAGCCCCCTCGCAACACCCAGCCCGCTGCTTGAGGAAGAAC[C/T]GAACACGGACCTCAAGCCCCCTTCTGTCCTCCCACCCCAATGACATTGTCTTTGATTTTGAGCCTGAGCCAGTGTTCAGAGGTAGCGAGGCCGTTGTGCGTGGCCGTGTCCTACACCTTGTCTCGTCTTTTGCTTGTTTGTCTGTCTTTCTGGTCTGTCTGTCTTCCACCTTGTATGTATTGTGGATGTATTTCACTCCTCCTTGTTTGAATTCACGCTTTCTCTGCCACTTCTTTCACACAAATGCTTTCACTGACATTTTTGAAGGGCTGCAGTCACTTTTCTTTAACTCAACGCACTACAAAATCACATAATCAGGCCAGCAATGCCACTAATGTGACATTTTACAAATATCTCTACCTTTAAATGATTATGTATTAATCAGTATTGAAGATGTGTTAATTGATTAATTTATTATTAAAAGTGCCTATTTATTGATGTTTTGTAATCCTCACTTAAAGATAATCTTTAACAACACAAGTACTTAATATCACCATTTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33417
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000023894 | None | None | 777 | None | 19 |
| ENSDART00000048391 | Nonsense | 437 | 817 | 10 | 20 |
| ENSDART00000131168 | None | None | 358 | None | 26 |
| ENSDART00000132650 | None | None | 575 | None | 13 |
Genomic Location (Zv9):
Chromosome 4 (position 11147738)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 12084365 |
| GRCz11 | 4 | 12083214 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCAAGCCCCCTTCTGTCCTCCCACCCCAATGACATTGTCTTTGATTTT[G/T]AGCCTGAGCCAGTGTTCAGAGGTAGCGAGGCCGTTGTGCGTGGCCGTGTC
Long Flanking Sequence:
GGCCCACATTAGCTTTGTTTACATATAAAGGGTGGGGTTTATGACATATACTGCAGAAAGCCACCAGGGGGTGATCAAAATATTCTGGCTTCACTTTTTAAGACTTTCAAGGTCACACCAGTAAAAAAAAGACTGTTAAACCTACAGTTTCATGCCTTCAAAATAAACACGTTCATATAAAAGCAACAGATCAACACAATGGTGAATAAATGATAACCGAACAATACTTTTTGGCTGAACTATCCTTATAAGGACAGACTGGCTCTGTGTCACCTAGAATCCACTTAATGATCTGTAAACAATGTCTGAGAGTAGACACAGGATTTTTGGTAGTGGGTAACTGGAGGTGCACCTGAGCTTCAGGGGCCAGTGATCCCGTGTCTGTCTCTCTCCCCCCTGCAGCCCCCTCGCAACACCCAGCCCGCTGCTTGAGGAAGAACCGAACACGGACCTCAAGCCCCCTTCTGTCCTCCCACCCCAATGACATTGTCTTTGATTTT[G/T]AGCCTGAGCCAGTGTTCAGAGGTAGCGAGGCCGTTGTGCGTGGCCGTGTCCTACACCTTGTCTCGTCTTTTGCTTGTTTGTCTGTCTTTCTGGTCTGTCTGTCTTCCACCTTGTATGTATTGTGGATGTATTTCACTCCTCCTTGTTTGAATTCACGCTTTCTCTGCCACTTCTTTCACACAAATGCTTTCACTGACATTTTTGAAGGGCTGCAGTCACTTTTCTTTAACTCAACGCACTACAAAATCACATAATCAGGCCAGCAATGCCACTAATGTGACATTTTACAAATATCTCTACCTTTAAATGATTATGTATTAATCAGTATTGAAGATGTGTTAATTGATTAATTTATTATTAAAAGTGCCTATTTATTGATGTTTTGTAATCCTCACTTAAAGATAATCTTTAACAACACAAGTACTTAATATCACCATTTAATTAAAACATTTCAGAATGAAAATTCACTTACGTTATTTAAAATTAGTCTGTGTTTATTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20231
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000023894 | Essential Splice Site | 516 | 777 | 12 | 19 |
| ENSDART00000048391 | Essential Splice Site | 556 | 817 | 13 | 20 |
| ENSDART00000131168 | Essential Splice Site | None | 358 | 19 | 26 |
| ENSDART00000132650 | Essential Splice Site | 516 | 575 | 12 | 13 |
Genomic Location (Zv9):
Chromosome 4 (position 11143679)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 12080306 |
| GRCz11 | 4 | 12079155 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCACTCCACAGCAGCTACAAGCCTTTAAGAATGAAGTGGGTGTCCTCAG[G/A]TAAAAGAAAGCCTAGTGTTCCTGTAACTGGCAATGAGGATGCATCTGAAA
Long Flanking Sequence:
ATTATTAGATTTATTTATTTTTTTTATTGTCAGTGCGTTATTTGCAAATGTTTTATGTGATATTCCAGTTTTGCGCACAAGTCTAATTAACACATTTGGATAGAAACAAACCTATAGACTTTCTTACAATGGATATCCATTTCTTACAATGGAAATATGATTCGAATGCAATTATTACAATATAGTCTCCTTTTGCAATTTGTCTTGTTTAAAACATTTGTTCTGTATACACAATAGCGTGATACACAGTGTTTTTGGTTATATACATGTATTTGTTGCAGCTTAGGTCAATATTGAGCTAATACCATACACCATGATAAACCCTTCAGCAATTAATTTCAACAAGAAATGTTGATACCGGCAGAAGCCTAATCTAAAAGTCTAAATCGTATGTTCTTCCTCTGTTTTTTTAAAGGTGACGTGGCGGTAAAGATGTTGAATGTTACAGCTCCCACTCCACAGCAGCTACAAGCCTTTAAGAATGAAGTGGGTGTCCTCAG[G/A]TAAAAGAAAGCCTAGTGTTCCTGTAACTGGCAATGAGGATGCATCTGAAATTGCATACTCCTTTTATTCTTGGGCAAAGCCAATGGCAAATCGATGATCAATTCATTGTGGATAATTCTTTAATTCCCTTGGGGGGTGTTTACAATGTATAATTCTATACATTTTTCCTGTACTGAACAAAAATTGCAGGATTAAAAATAACTTCATCACAGCATATTTAAGAAAACGATAACTAATAAATATCACTAATGCATATATAACATATCTATGATATATAACAGGCAAGACAAAACATCCTTCATTCAAACAAATAAATAAATAAATACGTCCCTAACAAATGGTTTCGCTAATAAATACCAAGAGTAATAATATATATATCCAAGACATTACTGAAACATTACATTTAATTTAATATTTGATCAAGTATTGATAGTGTGTGAGATTGCTTAATTGTTTTTCACACAACCTAAGATGGTGATTTTAATTTTGTTTTCCTACAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40247
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000023894 | Essential Splice Site | 720 | 777 | 18 | 19 |
| ENSDART00000048391 | Essential Splice Site | 760 | 817 | 19 | 20 |
| ENSDART00000131168 | Essential Splice Site | None | 358 | 25 | 26 |
| ENSDART00000132650 | None | None | 575 | None | 13 |
Genomic Location (Zv9):
Chromosome 4 (position 11140076)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 12076703 |
| GRCz11 | 4 | 12075552 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTCAAATGTTTTTATTTATTAAAGATATACATGTAATTTATTTATGGCA[G/T]ATCTTGGCCTCCATCGAGTTATTGGCACGCTCTCTGCCCAAAATCCACCG
Long Flanking Sequence:
TATTATTCATGCCTAAGCATAAAAAGTGCAAGTAAATGATTGAATATTTCAGATAACTGTGGATATATACATGTAGGTATATTTTTATGAAGCAAAAATTACGTAAATGACTAAATATAAATAAAAATGTTTTAATTAAAATTAAGCTGATATTTAAAAATAATAAGATGAAAAACTTAATTAAATGATATTATAAATGGCATATTTGCAACTAATTTACATATTAGTCAATCATTATCTATCAATTATGTATTATTATTTTTCTTTATACAATTCCAATGAATCAGTGAGGCTATATTAGTGGAATAAACCAGATTTACATTTTACTGAAGGAAAATAAATATTAAAATATGACTTGGAACCTATACCTCTAATAAATCTAGAGAAATGTAGAATTTCAGGTGATTTCTTAAATTATTAATGCATTATTCTTGCTTAAAAATTCATGTTGTTCAAATGTTTTTATTTATTAAAGATATACATGTAATTTATTTATGGCA[G/T]ATCTTGGCCTCCATCGAGTTATTGGCACGCTCTCTGCCCAAAATCCACCGCAGCGCCTCTGAACCGTCTCTGAACCGCGCTGGCTTCCAGACGGAGGACTTCAGCCTATACACCTGCGCTTCCCCCAAAACACCCATTCAGGCCGGTGGCTATGGCAAGTGCACGTTCCTAATCCTCCTTCTTGACTTGTGTTGCATTCATTCAGCATCCAAACTGATGTTCTTTGTTGCACTTTCAGGTGAATTCACAGCGTTTAAATAGTGCTGCAAATCCTAAACCTCCATCCCTTGTCAGTTTTTCAGACGTCTTGTGTTCCTATGATGGGTTCATCCATAACAACACAGAAAAAGGACAAGTTTTCAAAGAATGTGCTGTTTTTCTTCCTCTTTACCCGAAGAGCTACGGCCTCAACGGAATTGCTTTAAAATAAAAACATCTCTGCAGGGTGTCACTTTACAAAAAAATAAATGTCATAAACATCGCCGGACAACTCTAATACA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20230
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000023894 | Essential Splice Site | 771 | 777 | None | 19 |
| ENSDART00000048391 | Essential Splice Site | 811 | 817 | None | 20 |
| ENSDART00000131168 | Essential Splice Site | None | 358 | None | 26 |
| ENSDART00000132650 | None | None | 575 | None | 13 |
Genomic Location (Zv9):
Chromosome 4 (position 11139920)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 12076547 |
| GRCz11 | 4 | 12075396 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTATACACCTGCGCTTCCCCCAAAACACCCATTCAGGCCGGTGGCTATGG[C/T]AAGTGCACGTTCCTAATCCTCCTTCTTGACTTGTGTTGCATTCATTCAGC
Long Flanking Sequence:
AAAATAATAAGATGAAAAACTTAATTAAATGATATTATAAATGGCATATTTGCAACTAATTTACATATTAGTCAATCATTATCTATCAATTATGTATTATTATTTTTCTTTATACAATTCCAATGAATCAGTGAGGCTATATTAGTGGAATAAACCAGATTTACATTTTACTGAAGGAAAATAAATATTAAAATATGACTTGGAACCTATACCTCTAATAAATCTAGAGAAATGTAGAATTTCAGGTGATTTCTTAAATTATTAATGCATTATTCTTGCTTAAAAATTCATGTTGTTCAAATGTTTTTATTTATTAAAGATATACATGTAATTTATTTATGGCAGATCTTGGCCTCCATCGAGTTATTGGCACGCTCTCTGCCCAAAATCCACCGCAGCGCCTCTGAACCGTCTCTGAACCGCGCTGGCTTCCAGACGGAGGACTTCAGCCTATACACCTGCGCTTCCCCCAAAACACCCATTCAGGCCGGTGGCTATGG[C/T]AAGTGCACGTTCCTAATCCTCCTTCTTGACTTGTGTTGCATTCATTCAGCATCCAAACTGATGTTCTTTGTTGCACTTTCAGGTGAATTCACAGCGTTTAAATAGTGCTGCAAATCCTAAACCTCCATCCCTTGTCAGTTTTTCAGACGTCTTGTGTTCCTATGATGGGTTCATCCATAACAACACAGAAAAAGGACAAGTTTTCAAAGAATGTGCTGTTTTTCTTCCTCTTTACCCGAAGAGCTACGGCCTCAACGGAATTGCTTTAAAATAAAAACATCTCTGCAGGGTGTCACTTTACAAAAAAATAAATGTCATAAACATCGCCGGACAACTCTAATACAGCTTACAATGGAGAAGAAAAAATAAAAGACTGATCCTGGTCACTGGAAAAGAAACAAACCCAAATAGATCAAATGGCAGGGATTAAATAAAAGAAAGATGAATGAGTTTGGGATGAATGGAACACAAGCCCCGCCTTTGCTCCACCCCTGGAGGGG
Associated Phenotype:
Not determined