ZMP

tlx3b

Ensembl ID:

ENSDARG00000017615

ZFIN ID:

ZDB-GENE-021021-1

Description:

T-cell leukemia, homeobox 3b [Source:RefSeq peptide;Acc:NP_739572]

Human Orthologues:

TLX2, TLX3

Human Descriptions:

T-cell leukemia homeobox 2 [Source:HGNC Symbol;Acc:5057]
T-cell leukemia homeobox 3 [Source:HGNC Symbol;Acc:13532]

Mouse Orthologues:

Tlx2, Tlx3

Mouse Descriptions:

T-cell leukemia, homeobox 2 Gene [Source:MGI Symbol;Acc:MGI:1350935]
T-cell leukemia, homeobox 3 Gene [Source:MGI Symbol;Acc:MGI:1351209]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa41648	Nonsense	Mutation detected in F1 DNA	Not yet available
sa2555	Nonsense	F2 line generated	Not yet available

Mutation Details

Allele Name:

sa41648

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000016575	Nonsense	41	300	1	3

Genomic Location (Zv9):

Chromosome 10 (position 22256925)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	22087263
GRCz11	10	22056715

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCAGCTTCGGCATTGACCAGATTCTCAGCGGAACCGATCAAGAATCACAG[C/T]AGAACTCGACCAGGAATAGTTCGGAGAGCAGCAGTGGCAGTAGCAGTGCG

Long Flanking Sequence:

CAAACGATCTGCATTTTAAAGAATGATATCGGAATACGCGTTATGTTTTGTGACTTAACCAAATGAAAGCCAATAAGGAAAGCGAGATTAAGCACTGTCCAATCAGAGAAGAGAACAGCGCAATGTGCTCCGTGCAGGGATCCATTGGAGAGAGAGAGTGCCAGGATTCTGCCAAGTCCTCGTGCCAAAAACTTTTCACCCATAGACGAATGCGTCCAAGCCGTCCTTAGTCAAGAATTGAATAGAGGGGTACTACATCACAAAGTAGATATTACTAGGGATTCCCTTATTTACAAAGATAGAGTTTTCCGTAGTGCAAATCCAGGACTGTTCGAAATTGTCTGTGGAATAAAACCGCTGGAAAGGTTCGGGTGGTGAGGATGGACCGAGCTCCAAGCTCCAGCCCAAGTGGCACCAGTCAAACATCACAACCAACCCAACATGAACCCATCAGCTTCGGCATTGACCAGATTCTCAGCGGAACCGATCAAGAATCACAG[C/T]AGAACTCGACCAGGAATAGTTCGGAGAGCAGCAGTGGCAGTAGCAGTGCGAGCGGAGGCTGTTACCATCTCGGCAGCCCAACGGGAGCGAGCGCAACGCCGTACACGACGCTTACCGGCACATTTCATGGTATCGCGGCTCCTTATGAGGAGTCCAGTCCATACGGAATGAACTTGACCCTTGCGCCCGGAGGAGTGATTAGGGTCCCGGCGCACAGGCCCCTTGCCGCGGCCGTTCCTCCACCTATGGCCAGCGCGGTACCCGGACTTGGGAGCCTCAGTTTTCCCTGGATGGAGAGCAGCCAGCGCTTTGCAAAAGACAGGTTTGCAGGTAAAAAAAAAAAAGAAAATACTCATGCCATTTCAACATGTTCCTTACGGGTTTCATACAAATATTCCTCTTGGTTAAAATGAGGAAAATATATTGATTGAGGAAAAACACAGCCTAATTTAAAAAATAATCAGAGCGAGAGCAAAATGGCAACTCAAGCTGAATAATGT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa2555

Status:

F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000016575	Nonsense	209	300	2	3

Genomic Location (Zv9):

Chromosome 10 (position 22254322)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	22084660
GRCz11	10	22054112

KASP Assay ID:

554-3065.1 (used for ordering genotyping assays)

KASP Sequence:

GCTTTCACAGACAAAAATACCTGGCCAGCGCTGAACGGGCAGCTTTGGCC[A/T]AAACTCTAAAGATGACAGACGCACAGGTCAAAACATGGTTTCAGAACCGC

Long Flanking Sequence:

AGCAAAATTGTTCATTATTTAAAAGTGTAATTCTTTATCTAAAATATTAATAGAAATTGTTCATATACATCTTATTTTTGCTGGGGTTTGCATTTAATGCATTATATATAAAAATGTAATTATTATTTGACAAGTGATAGTGTAGATGTACATTAATATCTTGTGAGTTAAAAAATAGTAAACCAAAAATAAAACTGATTATGAATATTAAAAATTTGAAATTAAGCTTTTTCTCATTTCTAAAAAAAAAAAGGCATATAAAGCTAAGTTACAGACTCTAACCCCATCTCTCATTTTGTAATTTTTCTTTCCTTGTCCATCTCACAGCAGCCTTGACGCCTTTTACTGTGGCTCGACGTATTGGTCACCCGTACCAGAACCGCACACCACCAAAGAGAAAGAAGCCTCGCACGTCCTTCTCCAGAGTGCAGATCTGTGAGCTGGAGAAGCGCTTTCACAGACAAAAATACCTGGCCAGCGCTGAACGGGCAGCTTTGGCC[A/T]AAACTCTAAAGATGACAGACGCACAGGTCAAAACATGGTTTCAGAACCGCAGGACTAAATGGAGGTGAGGCAAAGAAAGGGAAAAGGAGAATATGTTAATATGAAACATCAAGAAAACGTGGTGAAAGAAAGTGTGATCTGAGAACAAATGCACCATTTCACTAAAACAATATTTCCCATTAGATCTTTCACAAAATACAATTTTTCTAATTTTTTCCATTAGTTACTGTCCAATAATTTAACCTGTGAAAAAGTTGATTGTTTTACCTACAATGTCGTCATCTTGGAATTATAAGGTTCTATCTGCATTTTGAATGATTTTGAGATATTGAGCTTCAAAGTTTTTGCATTCCATAGCAAACAGAATGTGTGTAACATTTTTTTTTTTATAAAAAGTCTTAAAATGTAAACAACTTATAAAAAAACATCCTATAATATAAATAAGTTGTCATTTAATAAGAATATGTCAACTTAATTTTGACAAAAATGTCTGATAGAAC

Associated Phenotype:

Not determined