Busch Lab

ZMP

zgc:123068

Ensembl ID:
ENSDARG00000017489
ZFIN ID:
ZDB-GENE-051030-98
Description:
putative ISG12-1 protein [Source:RefSeq peptide;Acc:NP_001007133]
Human Orthologues:
IFI27, IFI27L1, IFI27L2, IFI6
Human Descriptions:
interferon, alpha-inducible protein 27 [Source:HGNC Symbol;Acc:5397]
interferon, alpha-inducible protein 27-like 1 [Source:HGNC Symbol;Acc:19754]
interferon, alpha-inducible protein 27-like 2 [Source:HGNC Symbol;Acc:19753]
interferon, alpha-inducible protein 6 [Source:HGNC Symbol;Acc:4054]
Mouse Orthologues:
Ifi27l1, Ifi27l2a, Ifi27l2b
Mouse Descriptions:
interferon, alpha-inducible protein 27 like 1 Gene [Source:MGI Symbol;Acc:MGI:1277180]
interferon, alpha-inducible protein 27 like 2A Gene [Source:MGI Symbol;Acc:MGI:1924183]
interferon, alpha-inducible protein 27 like 2B Gene [Source:MGI Symbol;Acc:MGI:1916390]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa38967 Nonsense Mutation detected in F1 DNA Not yet available
sa8727 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa8700 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38967
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046945 Nonsense 27 95 3 4
ENSDART00000140230 Nonsense 27 95 4 5

The following transcripts of ENSDARG00000017489 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 38003595)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 37480407
GRCz11 13 37606297
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGGAGCAATTGCTGCAGCTCCTGCACTTCTAACAGCTGCAGGTTTCACT[G/T]GAGCTGGCATTGCTGCAGGATCAGTTGCCTCCTGGATGATGTCAACAACT
Long Flanking Sequence:
ATCATGATACCTTGTGAATATCTATACCTTTACTCACATTACACCCAGCTTCAAAAGACCTTCAGGAAAAAAAGAAAGGCACAGTTTAGGAGAAGGCTACAAAAACACTTTAAAACCTGAAAAAGTGGTCTGGAATGTAATTTGATTTCAGGATGTATTACAAATACATAAGAATATTTATAATATATGACAAGTTATATATGAATATATGACAAAAAAAGTTAAAGTAATTTAAAGGGATATGATGATTTTTCAAAGGCATTGTAACTCTACCACAGCATCTTTCCATAACCTTAGCCATATTACTTATCAAAAGCAGAAATAGTAATACAATACAACATGAGCACAGAAAACATTGTACATAACAACTAAATTAAGCAGATTGTTCACTGTATGTGACAGTGATCCACTTAAAGTTGCTTTCTGGATCTATTTTTCTTCCACCTACAGCTGGAGCAATTGCTGCAGCTCCTGCACTTCTAACAGCTGCAGGTTTCACT[G/T]GAGCTGGCATTGCTGCAGGATCAGTTGCCTCCTGGATGATGTCAACAACTGCCGTGGCGAGCGGAGGAGGAGTCGCTGCTGGATCAGCGGTTGCTGTTCTTCAAAGCGCAGGTGAGTAAAATTCCTCAAATGAGTTAAAATGATTAATGCATGGAATAAAAAGACTTTCCATTTATGTGTTCAGGTGCAGCTGGAATCTCAATGGCAGGTCAAGCAGTTGTAGGTGCTGTGGGAGCTGCTATGGCCACTGCTGCCAGTATGGCCAGCAACTGTACTGGGTGACTGGAGAAACCTTGGCCAGTCTTTTTGTAGCATTTTACAAGGTTGCATTATGTTGATTCTCCAAATGCATGTTGTTCTTCCGATTGTATCTAGTATGGCTATTAAACCTTTATAAATCATGCAAATGTATGTTGTCATTTATTTTATTACTGATTAAAAAGACTTTGGAATCCACAATCAACACAAAATGCATACAATATGTGCTTTAACCTGATTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8727
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046945 Essential Splice Site 64 95 3 4
ENSDART00000140230 Essential Splice Site 64 95 4 5
ENSDART00000046945 Essential Splice Site 64 95 3 4
ENSDART00000140230 Essential Splice Site 64 95 4 5

The following transcripts of ENSDARG00000017489 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 38003482)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 37480294
GRCz11 13 37606184
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGAGGAGGAGTCGCTGCTGGATCRGCGGKTGCTGTTCTTCAAAGCGCAGG[T/G]GAGTAAAATTCCTCAAATGAGTYAAAATGATTAATGCATGGAATAAAAAG
Long Flanking Sequence:
AACCTGAAAAAGTGGTCTGGAATGTAATTTGATTTCAGGATGTATTACAAATACATAAGAATATTTATAATATATGACAAGTTATATATGAATATATGACAAAAAAAGTTAAAGTAATTTAAAGGGATATGATGATTTTTCAAAGGCATTGTAACTCTACCACAGCATCTTTCCATAACCTTAGCCATATTACTTATCAAAAGCAGAAATAGTAATACAATACAACATGAGCACAGAAAACATTGTACATAACAACTAAATTAAGCAGATTGTTCACTGTATGTGACAGTGATCCACTTAAAGTTGCTTTCTGGATCTATTTTTCTTCCACCTACAGCTGGAGCAATTGCTGCAGCTCCTGCACTTCTAACAGCTGCAGGTTTCACTGGAGCTGGCATTGCTGCAGGATCAGTTGCCTCCTGGATGATGTCAACAACTGCCGTGGCGAGCGGAGGAGGAGTCGCTGCTGGATCAGCGGTTGCTGTTCTTCAAAGCGCAGG[T/G]GAGTAAAATTCCTCAAATGAGTTAAAATGATTAATGCATGGAATAAAAAGACTTTCCATTTATGTGTTCAGGTGCAGCTGGAATCTCAATGGCAGGTCAAGCAGTTGTAGGTGCTGTGGGAGCTGCTATGGCCACTGCTGCCAGTATGGCCAGCAACTGTACTGGGTGACTGGAGAAACCTTGGCCAGTCTTTTTGTAGCATTTTACAAGGTTGCATTATGTTGATTCTCCAAATGCATGTTGTTCTTCCGATTGTATCTAGTATGGCTATTAAACCTTTATAAATCATGCAAATGTATGTTGTCATTTATTTTATTACTGATTAAAAAGACTTTGGAATCCACAATCAACACAAAATGCATACAATATGTGCTTTAACCTGATTTTATGCTTATTTATTATATACACATTTTTCTGTTTTTTTGTTACGATGAGGCAGTTTTAACGGGGACCTGTTATGCTCCTTTATACAACATTAAAAATGTTACCCCTAGAGTGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8700
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046945 Essential Splice Site 64 95 3 4
ENSDART00000140230 Essential Splice Site 64 95 4 5
ENSDART00000046945 Essential Splice Site 64 95 3 4
ENSDART00000140230 Essential Splice Site 64 95 4 5

The following transcripts of ENSDARG00000017489 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 38003482)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 37480294
GRCz11 13 37606184
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGAGGAGGAGTCGCTGCTGGATCRGCGGKTGCTGTTCTTCAAAGCGCAGG[T/G]GAGTAAAATTCCTCAAATGAGTYAAAATGATTAATGCATGGAATAAAAAG
Long Flanking Sequence:
AACCTGAAAAAGTGGTCTGGAATGTAATTTGATTTCAGGATGTATTACAAATACATAAGAATATTTATAATATATGACAAGTTATATATGAATATATGACAAAAAAAGTTAAAGTAATTTAAAGGGATATGATGATTTTTCAAAGGCATTGTAACTCTACCACAGCATCTTTCCATAACCTTAGCCATATTACTTATCAAAAGCAGAAATAGTAATACAATACAACATGAGCACAGAAAACATTGTACATAACAACTAAATTAAGCAGATTGTTCACTGTATGTGACAGTGATCCACTTAAAGTTGCTTTCTGGATCTATTTTTCTTCCACCTACAGCTGGAGCAATTGCTGCAGCTCCTGCACTTCTAACAGCTGCAGGTTTCACTGGAGCTGGCATTGCTGCAGGATCAGTTGCCTCCTGGATGATGTCAACAACTGCCGTGGCGAGCGGAGGAGGAGTCGCTGCTGGATCAGCGGTTGCTGTTCTTCAAAGCGCAGG[T/G]GAGTAAAATTCCTCAAATGAGTTAAAATGATTAATGCATGGAATAAAAAGACTTTCCATTTATGTGTTCAGGTGCAGCTGGAATCTCAATGGCAGGTCAAGCAGTTGTAGGTGCTGTGGGAGCTGCTATGGCCACTGCTGCCAGTATGGCCAGCAACTGTACTGGGTGACTGGAGAAACCTTGGCCAGTCTTTTTGTAGCATTTTACAAGGTTGCATTATGTTGATTCTCCAAATGCATGTTGTTCTTCCGATTGTATCTAGTATGGCTATTAAACCTTTATAAATCATGCAAATGTATGTTGTCATTTATTTTATTACTGATTAAAAAGACTTTGGAATCCACAATCAACACAAAATGCATACAATATGTGCTTTAACCTGATTTTATGCTTATTTATTATATACACATTTTTCTGTTTTTTTGTTACGATGAGGCAGTTTTAACGGGGACCTGTTATGCTCCTTTATACAACATTAAAAATGTTACCCCTAGAGTGTG
Associated Phenotype:
Not determined