Busch Lab

ZMP

epha2

Ensembl ID:
ENSDARG00000017354
ZFIN ID:
ZDB-GENE-990415-63
Description:
ephrin type-A receptor 2 [Source:RefSeq peptide;Acc:NP_571490]
Human Orthologue:
EPHA2
Human Description:
EPH receptor A2 [Source:HGNC Symbol;Acc:3386]
Mouse Orthologue:
Epha2
Mouse Description:
Eph receptor A2 Gene [Source:MGI Symbol;Acc:MGI:95278]

Alleles

There are 9 alleles of this gene:

Allele Name Consequence Status Availability
hu3575 Nonsense Available for shipment Available now
sa1266 Essential Splice Site Available for shipment Available now
sa33949 Nonsense Available for shipment Available now
sa40777 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa44642 Nonsense Mutation detected in F1 DNA Not yet available
sa33948 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa20802 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
hu3575
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025428 Nonsense 371 984 5 17
ENSDART00000136964 None None 52 None 2
Genomic Location (Zv9):
Chromosome 6 (position 45825020)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 45885954
GRCz11 6 45887836
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGACGTCACATACAGTGTGGCATGCGAGCGCTGTGAGGGTGGTCTGTG[T/A]ACGCTGTGTGGCGGAAGGGTGCGATTCGAGCCTGCGCAGACGGCCTTGAG
Long Flanking Sequence:
GAATTTAAATTATTGTGTGAACTATCCCTTTAATACAATGTGTAAATGTTATCTGTATTGTTTTAATTCATTAAATGTCTCATCATGTTCAACATTTCTTCGTGTCTACAGCTTGTGAACCGGGTTTCTACAAGAGCACTGATTCCAGCCAGCCTTGTGAAGTGTGTCCAGAAAACACCCAACGTTCGGGACGGGGAGCACTGTTGTGCCCCTGCATGGAGGGTTTCTACCGGGCTCCTACAGACCTAAACTCTGCTCCTTGCTCTTGTAAGTTTAAATCTTCATTCTGAAAAGTTCATTCTGAAACTACTGACCTAATTCTCAAACATTTTACACTGCTCTGCTTCTCTAGCTCTTCCTAGCCCACCCCGAGACCTGGTTTACACTCCTCTCCTGACAGCAGGAAGTTTGCAGCTGCTTTGGCGCCCACCGGCAGACACTGGTGGTCGGAGTGACGTCACATACAGTGTGGCATGCGAGCGCTGTGAGGGTGGTCTGTG[T/A]ACGCTGTGTGGCGGAAGGGTGCGATTCGAGCCTGCGCAGACGGCCTTGAGAGCCCCTGAGGTTGTGGTTAGCGAGCTGGAGCCTCATGTGAACTACACTTTTACAGTCGAGGCCCAAAATGGCGTCTCCCAGTTCAGTCGAAAGAGAGCCATGGCTAGCATCACAACAGTGCTTCACTTCACAGGTTAGATTTTGCATATAAAGCTATTGTAATGCCTAAATCACAGCTAATCACATTTAATTTGATGCTACTTGAAGCTGAGTTTTGTACCAGCGTGGGTAATTGTGGGCGGAGCTAGCTTGTGAGCTTCATTGCTTGTCACGGCTGGAGAAGATTAACAGATTAGTAAGGAGGGGAATTGACAACATGTCATGCCTGCTTAAGACATGGCGTATCAAATTCTGTTCACTTGTAATCTGTTTCGTTGATGGTTTTAGCCAAAATACTGATGACTGCTTGTGCTTCTGTTGTTCAGATGGCCCGAGGGTGCTGTACTTGA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa1266
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025428 Essential Splice Site 433 984 6 17
ENSDART00000136964 None None 52 None 2
Genomic Location (Zv9):
Chromosome 6 (position 45824545)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 45885479
GRCz11 6 45887361
KASP Assay ID:
554-1181.1 (used for ordering genotyping assays)
KASP Sequence:
GTTGATGGTTTTAGCCAAAATACTGATGACTGCTTGTGCTTCTGTTGTTC[A/T]GATGGCCCGAGGGTGCTGTACTTGAGAGTTGAAGATCGGACCACCAGYAG
Long Flanking Sequence:
GCGAGCGCTGTGAGGGTGGTCTGTGTACGCTGTGTGGCGGAAGGGTGCGATTCGAGCCTGCGCAGACGGCCTTGAGAGCCCCTGAGGTTGTGGTTAGCGAGCTGGAGCCTCATGTGAACTACACTTTTACAGTCGAGGCCCAAAATGGCGTCTCCCAGTTCAGTCGAAAGAGAGCCATGGCTAGCATCACAACAGTGCTTCACTTCACAGGTTAGATTTTGCATATAAAGCTATTGTAATGCCTAAATCACAGCTAATCACATTTAATTTGATGCTACTTGAAGCTGAGTTTTGTACCAGCGTGGGTAATTGTGGGCGGAGCTAGCTTGTGAGCTTCATTGCTTGTCACGGCTGGAGAAGATTAACAGATTAGTAAGGAGGGGAATTGACAACATGTCATGCCTGCTTAAGACATGGCGTATCAAATTCTGTTCACTTGTAATCTGTTTCGTTGATGGTTTTAGCCAAAATACTGATGACTGCTTGTGCTTCTGTTGTTC[A/T]GATGGCCCGAGGGTGCTGTACTTGAGAGTTGAAGATCGGACCACCAGTAGTCTGACCTTGTCCTGGGCTGTGGACCATCATGTGCAGAATCAACCCTCCCCTCGCTACGAGCTCATGTACCGCAAGAAGGTGATTAAGCCTCTTTTTTCTCTAACGTTCATTCATTTTCTTTTCGGCTTAGTCCCTTAATTAATCAGGGGTCGCCACAGAGGAATGAACCGCCAACTTATCCAGCATATGTTTTACACAGTGGATGCCCTTCCAGCTGCAACCCATCACTGGGAAACACCCATACACTCTCATTCACACACATTCACTACGGACAATTTCGTTTACCCAATTCACCTATAGTGCACATCTTTAGACTGTGGGGAAACCGGAGCACCTGGAGGAAACCCATGCCAACACGGGGAGAACATGCAAACTCCACACAGAAATGCCAAATAACCCAGCTGAGGCTCGGACCAGCAACCTTTTTGCTTTGAGGCTACAGCGATACC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa33949
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025428 Nonsense 586 984 9 17
ENSDART00000136964 None None 52 None 2
Genomic Location (Zv9):
Chromosome 6 (position 45821667)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 45882601
GRCz11 6 45884483
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGCTGAATTCCCACGTCAGACGGAGGGTTGATGGAGATTACTTTTCATG[T/A]CCAGGTATGACATGGATTTTGGCATTTGTGTGCATCTGTTTGGTATTTGA
Long Flanking Sequence:
AGTTTGAATGCTTTCGGGCATGAGAAAGTGTGTAACTTAGATGCATTGGTGATAGGCTGTGTGCGTGTGCGTGTGTGGTGCGTCAGTGTTTGTCAGTATAAGTAAAGTGAACTTCTTTTTTTATTCTCACAGCGGAATCTCGGACACAGAACAGTTCCATGGTTGTCATGGGAGCCATCGCCGGGGGCGGGGTCATGTTGCTGATTGTGGTGGTTATTCTGCTTCTGCACAAAAGGTTAGCGAACGTATCTCTGCTCTCACTTTTTCCAGTCTATTCTCTTCTTTATCTCTATCCAGACCGCAGAGCAGGATTTCCCAACTTGGCCTTCAATGCCTGCCCACACTGTTTACATTCCAGCTTTGATCTACAATCATGCTCATTTAAAGAAACCATCGAGATAGCAGCTTTAATTATCTCGCTAATGTGATGTTGAATGCTCTTTCATCAGGAGGCTGAATTCCCACGTCAGACGGAGGGTTGATGGAGATTACTTTTCATG[T/A]CCAGGTATGACATGGATTTTGGCATTTGTGTGCATCTGTTTGGTATTTGAAATGATCTGATGGTCAGCAATAACTTTGTATGAATCACTGAAGATCATCGTACAGTGGGTGTCGTCTAATCCAAGGTCAAATCTTTTCTTATTTTGAAGAAAAACTCCTTCCGTTGAAGACCTACATCGATCCCCACACATATGAAGACCCCTGTGCGGCCATCCTCAAGTTTGCCAGTGAGATTCATCCTGGTCACATCACCAAGCAGAAAGTCATTGGTGCAGGTCAGTGTTCATATTGTGTTAGCCGTATGGTATATTAATAGTATACATGGACTAATATAAATATCTAAATATTTTAGAATATATTTTATTTTTAAGTATTTTTGGGTTTATTTTAGTTGAAGTAAACATTTTTTTATTCAGTTTGTTATTCATTCATGGTAGAATATTGCGAAATGAATACACCAGATGACCTGAATAGCTTAATGTAGAAAAAAGAAATCTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40777
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025428 Essential Splice Site 629 984 10 17
ENSDART00000136964 None None 52 None 2
Genomic Location (Zv9):
Chromosome 6 (position 45821391)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 45882325
GRCz11 6 45884207
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGTGAGATTCATCCTGGTCACATCACCAAGCAGAAAGTCATTGGTGCAG[G/A]TCAGTGTTCATATTGTGTTAGCCGTATGGTATATTAATAGTATACATGGA
Long Flanking Sequence:
CTCTTCTTTATCTCTATCCAGACCGCAGAGCAGGATTTCCCAACTTGGCCTTCAATGCCTGCCCACACTGTTTACATTCCAGCTTTGATCTACAATCATGCTCATTTAAAGAAACCATCGAGATAGCAGCTTTAATTATCTCGCTAATGTGATGTTGAATGCTCTTTCATCAGGAGGCTGAATTCCCACGTCAGACGGAGGGTTGATGGAGATTACTTTTCATGTCCAGGTATGACATGGATTTTGGCATTTGTGTGCATCTGTTTGGTATTTGAAATGATCTGATGGTCAGCAATAACTTTGTATGAATCACTGAAGATCATCGTACAGTGGGTGTCGTCTAATCCAAGGTCAAATCTTTTCTTATTTTGAAGAAAAACTCCTTCCGTTGAAGACCTACATCGATCCCCACACATATGAAGACCCCTGTGCGGCCATCCTCAAGTTTGCCAGTGAGATTCATCCTGGTCACATCACCAAGCAGAAAGTCATTGGTGCAG[G/A]TCAGTGTTCATATTGTGTTAGCCGTATGGTATATTAATAGTATACATGGACTAATATAAATATCTAAATATTTTAGAATATATTTTATTTTTAAGTATTTTTGGGTTTATTTTAGTTGAAGTAAACATTTTTTTATTCAGTTTGTTATTCATTCATGGTAGAATATTGCGAAATGAATACACCAGATGACCTGAATAGCTTAATGTAGAAAAAAGAAATCTTGAATTTAGATAGATTGGGGTAATTTTGTATGAAAATTGGGATGTGAAATAATTGCAAGCAAGAGTAATTACAATAGAGCAAAGAAATAAAGTTAAATAAACATAGATTTATAGTTTTCTAGAGAGTCAAACACTATTCAGACACAGTAAGCGAGTAATGAAATGTAAAAATAACTCTATATAGTCTTAGTTATATTAATATTTCATTAAAAGTATTCTTCAATAAAGTTACAAATGTGCTTTTTTTTTTACCCGAACTCTCTTGAAATGCCTTTAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44642
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025428 Nonsense 659 984 11 17
ENSDART00000136964 None None 52 None 2
Genomic Location (Zv9):
Chromosome 6 (position 45819213)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 45880147
GRCz11 6 45882029
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCGGGCCGCAGTGAGGTCGCAGTAGCCATAAAGACACTGAAGCCAGGCTA[T/A]ACGGAAAAGCAGAGGCAAGACTTCCTCAGCGAGGCCAGCATCATGGGCCA
Long Flanking Sequence:
ATTATTAAGCCCTCTATATATTTTTCTCCCAATTTGTATAACGATGAGAGGAATTTTTAACATATATCTAAGCATAATAGTTTTAATAAATAATTTCTTATCCTATCTTTGTCATGATGACAGTAGATAACATTTCAAGATAGTAATAGTAGTATTCAGCTTGTAGTGGCGTTTAAAGGCTTGACTAGGTTAATTAGGTTAATTTGGCAAGTTAGGTTAAATTAAACAACCTAAAATTGTTTTAAAATATAAAAACTGCTTTTATTCTAGCTAAAATAAAACAAATAAGACTTTTTCCAATAGAAAAGATATTTTAGGTATTACTGTGATTTTTTTTTCTGTGTACAATTTTACCGGACTTCATTTTATTAGTTAAGATCAATAATTTTAAGAACCCATAATTGTCCAACAGGCGAGTTTGGGGAGGTGTTTCGTGGCTCTCTGAAGATGCCGGGCCGCAGTGAGGTCGCAGTAGCCATAAAGACACTGAAGCCAGGCTA[T/A]ACGGAAAAGCAGAGGCAAGACTTCCTCAGCGAGGCCAGCATCATGGGCCAGTTTTCCCACAAGAACATTATCCGTCTGGAAGGTGTCGTCACCAAATGTAAGTAATGTAATGTAATCAGATTATAAATGCATGCTTCTGGCAACTCTACATAGCAGTGCATGTTTTAACAGGATGTTCTCCTTCATTTCAGTCAAAGATGCCATGATTATCACCGAGTACATGGAGAATGGAGCTCTGGACCAGTATTTAAGGGTGTGTTTTGGTCTATGAATAAACAAATCTGAATAATCTGAAATGTATTAGAATCACTGATGATTTTATTTGTGCTTAACAGGATCACGATGGGGATTTTTCCTCATACCAGCTTGTGGGGATGTTGAACGGCATTGCAGCAGGAATGAAGTATCTCTCAGACATGAACTACGTCCATCGGGACCTCGCAGCTCGCAATGTGCTGGTCAACAGCAACTTGGAGTGTAAAGTGTCCGATTTCGGCTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33948
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025428 Essential Splice Site 832 984 14 17
ENSDART00000136964 None None 52 None 2
Genomic Location (Zv9):
Chromosome 6 (position 45816071)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 45877005
GRCz11 6 45878887
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTGATGTCATTTGGAGAAAGACCCTACTGGGACATGAGCAACCAAGAGG[T/C]ATGGAGTGTTACTTATGTTTTTTTGATCGATGGCTATACATCAAAATGGG
Long Flanking Sequence:
AGGTCACTGGTTCGAGTCCCGGCTGAGTCAGTTGGCATTTCAGTGTGGAGTTTACATGTTCATGTGGGTTTTCTCCAGGTTCTCCGGTTTCCCCCTCAGTTTAAAGACATGAGCTATAGGTGAATTGAGTAAAATATATTGGCCGTATAGTATGTGTGTGAATAAGTGTGTATTAATGTTTCCCAGCTGGAAGGGCAACCGCTGTGTAAAAGCGGATACTGGATAAGTTGGTGGTTCATTCCGCTGTGACGACCCCTGATGAGAAAAGGAACTAAGCCAAAAGAAAATGAATGAATGAATTGTATACAAAAGTCTGACATTGTATGTTGTTTGTTTTATTTGTTTTTAGGGCGGAAAGATTCCTATTCGCTGGACTGCACCAGAGGCAATAGCTTACAGGAAGTTCACTTCTGCTAGTGATGTGTGGAGCTTCGGCATAGTCATGTGGGAAGTGATGTCATTTGGAGAAAGACCCTACTGGGACATGAGCAACCAAGAGG[T/C]ATGGAGTGTTACTTATGTTTTTTTGATCGATGGCTATACATCAAAATGGGTGATGATGAAAAACATGAATTAAGTAAAAGACATTTCTAGGAAACAAAAAGTGAAAGGGTTCGTTTACCTCAAAATGTTGTCATTCTGAACTCATAAGTTTTTAGTTGGTCCTCTGGGGCCAGATTCTCCAGCAGTACGTAAGTTTAAACGTAGCCTAGTTGTGACTTAAAGGGACACTAAGTTAAAACATTACTAAAATTTATTTGTGTTGCACCACTGAACGTAGTTTAAATGTGACGCTATGTTACAACTAAATATTTACAGCAGCCTCCCCCATGTATAACGGTAGAAAAGAGACGACAGCGATTATAATGAAGAATGATCTTCCTCTACTCGCAACCTTATTTTCCTCCCAAATCTCGATGTATTTTTTTCAGTTTATGAAATGTGTTTAATTTTTTTTCAAGGAGTGTTTTGCGTTATTCATATTCATCAATTAAAACAAGAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20802
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025428 Nonsense 970 984 17 17
ENSDART00000136964 None None 52 None 2
Genomic Location (Zv9):
Chromosome 6 (position 45812399)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 45873333
GRCz11 6 45875215
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATTGGAGTTCGGCTGGCAGGTCATCAGAAGAGAATAGCATACAGCATTT[T/A]GGGCCTGCAAGACCCAGTGGGGGCCTTGGATTTGTTTGCAATGTGATAAT
Long Flanking Sequence:
AAAACATCAGCATGCAAAATAAGACAAAAGATCATGGAAATCCCATTTGCCCAAGTCATTTTTAACAAATGATCCACTTGTGATTTATACTTCAAAACAGCGCAGAATAGTGCATGAAATACAAACTGGGATGCAGCAATGTTCACTAAAACCTGGTTTATTTTCATCACAGTGTCTCCATTCGTCTACCCAGCACTAGTGGTTGTGATGGCGCCCCCTTCAGGTCAGTGGACGAATGGCTGGAATCCATCAAAATGGCCCAGTACAGAGAAACCTTCGCCCTCGCTGGCATTAAATCTTTCGACCAGGTGCTGCGCTTGAAAATTGAGTAAGTATCCTCTGCATTCAAAAACCAAACACAAATGTAACCAAATGTGTATTACCAAAAATTCCATATGCCATCATATAACGTTTTTCTATCAACTTCTTTTTCTAAAGGGACATCGGGAATATTGGAGTTCGGCTGGCAGGTCATCAGAAGAGAATAGCATACAGCATTT[T/A]GGGCCTGCAAGACCCAGTGGGGGCCTTGGATTTGTTTGCAATGTGATAATACGGTCGACTGAAGCAACACTGTTTTGAATGGATTTTAAAAAAAACTGACTAAAGACTAGAATGCCCTTTTTCAATCAAACGGACTCCCTCTGGGAATATGAACACTTTACTGTTAGTTTGTTTATGCATTTTATAGTCTATTTTTCCACATGTCAGATGGACCCTTATGCTCTTTGCCATGTTTTAAACATAAGCCATATTAAGCACACGTATGATGGTAAGCTTTGAAATGCTATAACTACTGTCTCAGGTCTGATGATTAGGGTACTATCAAGTCTACGGTAGTAACCTTGGATATTACTGTGGTGCCCTTATAGTGAACAAAGCTGCCCGAATATGAGGGGTTGAAGTCTGATTAAACTTTGTACAATTGTAATTGTAAAAATGTTTGTAGTAAACATGATTTTTTTTTTTTTGTCAAATTGTTGACCTGCATCCTTTTCTGTCAA
Associated Phenotype:
Not determined