Busch Lab

ZMP

kdr

Ensembl ID:
ENSDARG00000017321
ZFIN ID:
ZDB-GENE-041001-112
Description:
Vascular endothelial growth factor receptor 2 [Source:UniProtKB/Swiss-Prot;Acc:Q5GIT4]
Human Orthologue:
KDR
Human Description:
kinase insert domain receptor (a type III receptor tyrosine kinase) [Source:HGNC Symbol;Acc:6307]
Mouse Orthologue:
Kdr
Mouse Description:
kinase insert domain protein receptor Gene [Source:MGI Symbol;Acc:MGI:96683]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa13239 Nonsense Available for shipment Available now
sa43425 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa43426 Nonsense Mutation detected in F1 DNA Not yet available
sa23684 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa13239
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049204 Nonsense 121 1357 3 30
Genomic Location (Zv9):
Chromosome 20 (position 22304991)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 22333158
GRCz11 20 22232831
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCTATAAGAGCMTGCCAAAAGAGGATGGGAARACATCTGWAGCTGTATA[T/A]GTCTTCATACAAGGTATCATTGTCATGTCGGAAAAGTTTTAAGACAATTT
Long Flanking Sequence:
GATATGTTTTATTCTTGCAGCGATAGAGCTCAGGTTTGTACCTGATCCTCCAACCTTGAACATCACTGAGAAGACTATCAAAATCAATGCTTCAGATACACTTCAAATCACATGCAGGTAAACTTTCCATCAGTTGTTTAATCCTTATTATAACAAAGTTACTTTGTCTCATATTCTGAATAAGGGATACTGATTTTGTTTATTGCTTTGTTTGGTTTACAATAATAACATATAGTAAACAATGTAATTTTGTTATCAATTTTCTCTATTAATAGTCTTTTTTTAAATCTGTTTCTCAGGGGTCGTCAAATTCTGGAGTGGTCCACACCTCACAACCGGACCAGCTCTGAAACCCGGCTCACTATATCCGACTGTAGTGGCGATGGACTATTCTGCAGCACTCTGACACTTTCCAAAGCTGTAGCCAATGAGACAGGCGAATACCGCTGCTTCTATAAGAGCCTGCCAAAAGAGGATGGGAAAACATCTGTAGCTGTATA[T/A]GTCTTCATACAAGGTATCATTGTCATGTCGGAAAAGTTTTAAGACAATTTTTAAAATACTCCTACTTTCTCTCTTAAGTAAAGTGGGAAAGAGAGTTGGAATGTTGCAAAAAATGTGTCCATCACATACTTCCTTTGTTATCCTTCTGGATAACCCTTTGACCTCTTCATCCTTCATAACCTCTTCACCACTACATTTTACCTCCCATTTCAGCCAGCTGTAAACTCCTCCCTTGTCCAGACAGACAAAATATAGGAAATAGCTTGTTTCGAGTTTTAAATGTGGTTGTGTAAACCTGCATTGCTTTCTGTGCCTGCAGATCCGGACTGGTACATTTGTTGTCCATAAGAAGTGTCATGTCTCTTATACAAGCTAAAAAGAATAGTTTTTGCAAAAATCATTCACCCTGGGTTTTTTTTTTTAATAAAACCTATTTGAATTTCTTTCGTTTGTTGCACCTAAAGGGAAAAAAGCATATTAGGTTTAGTTCCTATAGTACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43425
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049204 Essential Splice Site 268 1357 6 30
Genomic Location (Zv9):
Chromosome 20 (position 22309482)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 22337649
GRCz11 20 22237322
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGCTCAATGTTGGAATCGACTTCCAGTGGACCTTCCCTCATGAGAAGG[T/C]CAGTAATGGAGAGAAATGCCCAGAGTTCAGTCATTTTTACCTCTGATTGG
Long Flanking Sequence:
CTTATAAAATATATCAAAATAAAAAACAGTTGTTTTAAATTGAAATAATATTTCACAATACTACTCATTTTATTTTTGAAGAGACTTTTTGAAGAAACATTCCTACTGATCCCAAAGTCTTACTTATAAACTTTTTGATGGTGGTGTAAGCATCTGACATACAGTATGCATTGATTATGCTTACTCAATATCATGTCAAAAGCATGTCAAAAAGTGATAAAGCTTTTGTTTTTGAGGAGACTTGCTTGTTTCAGAATGTTTTGTTGATACTGAGAACAGTGTGGTGTGAGATCAGCTGCCTGGGTCTCAAGAGAACAATGCTCCTCCCGGCACGTCTCTCACACCCCTTCCCTCTTCCGCAGGATACAAGATCTATGACCTCACCCTGAGTCCACAGCATGAGAGGCTGACGGTCGGAGAGAGACTCATACTCAACTGCACCGCGCACACAGAGCTCAATGTTGGAATCGACTTCCAGTGGACCTTCCCTCATGAGAAGG[T/C]CAGTAATGGAGAGAAATGCCCAGAGTTCAGTCATTTTTACCTCTGATTGGTGACATTTGTCACAATTGTGATTACCTCAACATAAAAAGACCAGCCCTTGGAGATTTTTTTTCTGTGGTCTTTTTCCTGTTCCCCTTCAGTATGTGCTGTAAGTTTGCAATGTACGGCGATGAAAAACAGCCAGAAATAGTCTAAACAAAAGCAGTCTGCTTCTTTTTTCTGATTGCAGGTGTCTGACTGCTTATGTCTAAGATACAGTTTCAAATACAATTTCACTAGTGCCGTTTAATGGGGTCAAAATTTTCAAATTGTTTTAATAACTGATTTCTAATAACTATTTTATTCTGTCTTTGACATGATGACAATACACATAATGGGCCCTATAATACACCTGTTGCAATAAGGCGCAAGATGTGTTTGGCGCGATTGGTTGCTATTTTCAGACCAGCACCACCATAATTTACAAGTTTTGCACCACGCAAATCCATTTGCGCCACTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43426
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049204 Nonsense 586 1357 13 30
Genomic Location (Zv9):
Chromosome 20 (position 22326174)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 22354341
GRCz11 20 22254014
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTGAAGGACAGGATGTTATAATGCGTTGTGTAGCAGACCGGCTGCTGTA[C/A]TATAACTTGCGCTGGTATCGGGTAGCAAATGTAGCCAACCATGATCCACC
Long Flanking Sequence:
CATTTTACGGTATTTATCTCATTAAATCAAAGTGGATAAACCAGATTCAAAGACTTTCTTGAAATTCATGTACTTTTTTTATCCTAACATTTAATTTTGAAAATGCAAAAGATGAGCTTTTTAATTTATGCACCAAGTTTCTGTATTGAGGGTTAATCTTGATAAATCTGGTAAAAATGCATTTTATACACAATGTGCCTTTCTGCAGACCATCAGCACTCTGAAGATCCAGAAAGCAGTGGATCATGCCCTATACAGGTGCATCGCTACCAATAAGATGGGTCAAGATCAGCGAGTCATTGTGTTTCAAGTAACTCGTAAGTGCCTCCAAACCTATGACAATCCCAAATTAAATTGGATTTAAGTAAAGATATAATCAAGTTCAACCTTCATATATTTGTCTTATTCACAGGTTTTCTCAACCTAAGCGTCCTCCCCTCCAGCAGCCCTATTGAAGGACAGGATGTTATAATGCGTTGTGTAGCAGACCGGCTGCTGTA[C/A]TATAACTTGCGCTGGTATCGGGTAGCAAATGTAGCCAACCATGATCCACCTCCAGCAGCTGTGCCGTGTGATACTCTCACACTGTCACACTTACACCAGCCCAACGTCACTGTTTCAGGCCTGCAGGGGACCAATGTCACACTGGACATGCCCATACCCAATGCCACAATGATGGACCAAGGCTTGTACGCTTGCCAGGTGGAGATTGTGGGCACCAATGAGAAAACCTGCTTACTTCACAATCTCAGACTCAGAGGTAGGTCCTTAGTTTACATTGAGTGGAAACCTGTTTGAAAACAGTCATTATTTTTAGTATTTCAATTGTTGGAGATGCTAAAGTGTGGTATGTGTGGTGGATACACTAGGGTATGGCTAATTTCAGACTTGACTGTAATTATCTCAGTGTGCTTTCACATCTGTTGTTCAATTCATTTGGTCCAGCCCAAGGGCAACATTGTCGCAATTTTCTGCCATTTTGGGTCCTTTTCACACCACACTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23684
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000049204 Nonsense 1131 1357 25 30
Genomic Location (Zv9):
Chromosome 20 (position 22344186)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 22372353
GRCz11 20 22272026
KASP Assay ID:
2261-4232.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCTCCATATCCAGGTGTGTGCATTGATGAGTCTTTCTGCAGGCGACTT[A/T]AAGAGGGAACCAGAATGAGAGCTCCAGATTACGCCACGCCTGAAATGTAC
Long Flanking Sequence:
TCTCACAGATTATTTTCTCTTTATTTTTCAATACTTGGAATACAGTACTAATAAACTCATCCATAATATTACAGTGGAAAGACTCTTTTCAAGTTTTTTTTTTTGGTTATTCTAGGTCTGCTGAAAGTAATTTGTTCATTCTAATAAGTCGACTTTTAATATCCAATAGGTAAACTGTAAGGAGAATAATGACACCTCATAGTATGTTGTTTTTTATAGCACATTACTGATTGATTATAATTTAATAGAAGCTCCTTAATAATTCACGCAAAAGCATTGTGGTTGGAAAAGGGCAGATTCTGTGCTCTAACAAAGATCCATAGAAGGATCTTTACTGAACCATTAATATCAGTAAAGAAGCTTTATATAAACAATACTACTGGAAATAGTTTAAACCTACAGTATTTGCTTGACATGTCCCGTTGACCATTTTTTTCTTTGGTGCAGGTGCATCTCCATATCCAGGTGTGTGCATTGATGAGTCTTTCTGCAGGCGACTT[A/T]AAGAGGGAACCAGAATGAGAGCTCCAGATTACGCCACGCCTGAAATGTACATAAATATATTTCACATTTTTAAAATGTCCCCATTATTCTACATTTTTAAGGTTTCTAGATTTGTTTAGTAGGTCTCCTACAGTGACTTTGATGTGATTTCTTTTTTTTTGTCAGATACCAGACCATGCTGGACTGCTGGCTTGATCGACCTTTAGACAGGCCAACTTTTACTCAGTTAGTTGAGCATCTGGGTAATCTGCTACAAGCTAGTGCTCAACAGGTTAGACTTCATTCCAAGTATATTTTTCTTGCAATTTTTAATTTTATTTATTATTTTATTTAATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTCATTTTTTAGAAGTAGAAATTGATTCTTGATATAGATAAAATTGACCAGGGTTTAAAAAAACATATATATTTTTTTATTTAATTTAGTAATTTTTTCATGTTTTGGTGAGCCTAAATGACTGTTGTTT
Associated Phenotype:
Not determined