Busch Lab

ZMP

INT3_DANRE

Ensembl ID:
ENSDARG00000016811
Description:
Integrator complex subunit 3 [Source:UniProtKB/Swiss-Prot;Acc:Q1LXC9]
Human Orthologue:
INTS3
Human Description:
integrator complex subunit 3 [Source:HGNC Symbol;Acc:26153]
Mouse Orthologue:
Ints3
Mouse Description:
integrator complex subunit 3 Gene [Source:MGI Symbol;Acc:MGI:2140050]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa43289 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa23531 Nonsense Available for shipment Available now
sa6559 Nonsense Mutation detected in F1 DNA Not yet available
sa43290 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa14360 Nonsense Available for shipment Available now
sa29217 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa43289
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067793 Essential Splice Site 220 1017 7 29
ENSDART00000124755 Essential Splice Site 220 362 7 20
ENSDART00000130401 Essential Splice Site 220 362 7 11
Genomic Location (Zv9):
Chromosome 19 (position 27132154)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27062266
GRCz11 19 26646489
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCTCAGACAAAGAGAGGTGGACTTCTGCATCGGGCTGCTCCGAGAGAGG[G/A]TGAGTACAGTGATGTCTTAAAACAATGTGCCCATATTCTCTGTTTCTTTT
Long Flanking Sequence:
ACTGGTGAAGAGTGGAGTCATTGGAGCAGATGGAGTCCTCATGACGCTCATGAAACAGATCGCTGGTACGTTCACACACAACTGCCAATCATGCTATATACTTACAACGTATTCCTAAATGTGTGTGTGTGTGTGTGTTTGTGTGTCTAACCTACGTCACTCTGCAGGGGGAGACATTTCCAGCAAAAACCTGTGGTTGGCAGAGAATGTGTTGGACATCTTAGTGGACCAGAGGTGAGAAGTTGAGTCAAACTGCATGTAATGTGACTGCTGCACTGTAGGAGTAAACTACGTCCATGCAAATCGACCAGTGTGAGCTTATTATTCAGTCTGGTGAATGTGTCTGTGTGATGGACAGGGAGTGGGTGCTGAAGAGCGGGATGTTAGTGGCCATGTCTTTGTACACGTACCTGCGGCTCATAGTGGACCATGGTACGACAAGCCTGCTGCCCCTCAGACAAAGAGAGGTGGACTTCTGCATCGGGCTGCTCCGAGAGAGG[G/A]TGAGTACAGTGATGTCTTAAAACAATGTGCCCATATTCTCTGTTTCTTTTAAATAAATAAAATGCACTTATAGGATCATTTTTAATTAATTATCTGTGTGAATGAGTTTATGCAATAAAGCCTACTGCATCATATTTAATGAGCAATTTTCTAAATAATACCAAGATTACTCTTTTCTGAAACAAATGCACAATCTCTTACATTCCTTCTGTCATCTTATTTATAGTTCATGCATATTTAGCAAGTAGCAAAAGCTTTTTAGGGTGTTTTCACACATGGCTTGTTTTGATCATTTTGTTTTGGTATCTGATGATTTTTTTCACATAGTTCAGTCAATTTTGGCATTTCCGAACAGCAGGCACACTCTGATGTACAACAAAATCATCAGTCTGAAAAATTTAAGTGATTTATTTAACCTATCCTTTTTTATTTTATAATATACAAACCCAAATCAGAAAAAGGAATGCATGTTTATTTGTATATTATTTTGGGGAAAAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23531
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067793 Nonsense 272 1017 9 29
ENSDART00000124755 Nonsense 272 362 9 20
ENSDART00000130401 Nonsense 272 362 9 11
Genomic Location (Zv9):
Chromosome 19 (position 27139537)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27069649
GRCz11 19 26653872
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAAATACTTTTTTTTTTTTCTTTTAGGTATATTGCAGCTCCTTACCTCT[A/T]GAACCTCACGAAAGTTTCTGGCCTGTCGACTCACCCCTGACATGGAGACC
Long Flanking Sequence:
CGATGTGAAGTGTAAACAAAGTGGGGTCACGTTAATCAACACACGGTAGGGAAAGTAATGGAAAAAATTTACCTAAAAAGAAACTTTGATCGATTATAGGTTCTGAATGTCGATTCCGATCATTATTTTTTTTTTTTTTCGATTAATCACCCAGTCTTAGTAAATGTTTATGTTTAGTTTATACAGACGTTTTGTATGTTTAAAGTGTTCAAGTGTTGTTGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTATAGTTCATGGAGTGTTTTATCATCGGGAGGGATCTGGTCAGACTCTTACAAAATGTGGCTCGTATTCCTGAGATGGAGTTGGTGTGGCGAGACCTGCTGCACAGTCCTCAAACCCTCAGCCCACAGTTCACAGGTGTGCAAGAGTGCAATTCATAGATGGAATACACACAATTATTAAATATTGAAATATTAAACAAATACTTTTTTTTTTTTCTTTTAGGTATATTGCAGCTCCTTACCTCT[A/T]GAACCTCACGAAAGTTTCTGGCCTGTCGACTCACCCCTGACATGGAGACCAAGCTGCTGTTCATGACCTCACGGGTAAAAATGCACACAAAAAAAACTGACACATTAATAATTGTGACTTGTATATCAAACGCTCTTGCTTTCTGTGTTTGCAGGTTAGGTTTGGTCAGCAGAAGCGATATCAGGACTGGTTTCAGCGGCAGTATCTGTCCACAGCTGAGAGCCAATCACTGCGCTGTGACCTCATTCGTTATATATGCGGTGTGGTTCATCCATCTAATGAAGTACTGAGCTCAGATATTTTGCCACGCTGGGCCATCATTGGCTGGCTTCTGACAACCTGCACGGTAGGAGGCTGTTAAAAGCAATTTTGAAAATATGACACCCGCAACTACTCCAGAATCGCTAGAAAGCACATGTTTTTTCTCTATGTTTGGAGTTCATATTAATGCTGAACATCAATCACATCTTTCCATGCAGTCTAATGTTGCTGCATCAAAT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa29216
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067793 Essential Splice Site 483 1017 14 29
ENSDART00000124755 None None 362 None 20
ENSDART00000130401 None None 362 None 11
Genomic Location (Zv9):
Chromosome 19 (position 27142948)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27073060
GRCz11 19 26657283
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAGAACGTTTCCCTGAGTTCTGCAGTTCCCCCTCACCGCCCACAGAAGG[T/G]CAGACCTGCACATCACTGTTTCAGTGAAACATAAAATCCAAATCAATCCA
Long Flanking Sequence:
TGTTTTTACGACTTGATTCCACCCACATTTTCCACATCACAGAAGTCACAGGGCCAGTCTAGTCCTGTCAAAAAAGTTACACCCTACATTCTTTTCTACTGTATATTTTGTTTGACTCAGAAATAAGTAACCTAATTCAAAGTGTGTTATGAATAGCAGCTATTGTTTTAAAGTCTCACCTGCTCTCATATTCTCATTCAGATCATCCCACACTTTTTCCCACCTCTTGAGGGTCAAGTGCGACAGGGCGTCTTCAACTCTCTCAACTTCATCATGGAGAAGAGAGTTCTGGCGTGAGTATAACACACACTCTATCACGAACAGCAGTCGTGTGTCCCTGCTGGTAGAGAGACTTTCTATATGATTATCCTGAATTGCTCTTGCTCTCTCAGTCATCTAGCACCTCTGTTTGACAACCCTAAACTGGACCGTGAGCTGCGGTCTATGTTGAGAGAACGTTTCCCTGAGTTCTGCAGTTCCCCCTCACCGCCCACAGAAGG[T/G]CAGACCTGCACATCACTGTTTCAGTGAAACATAAAATCCAAATCAATCCACCAGAAGTGTTATACAAAACACACATTCTGGCATGCTTTTCAGTTTGCTGTGATTGAAGATAAGCTGAAATGGTTTCCATACTAGACAATAATGATAGTGTAATATGTTTATTGTTTCATACCAGCAGTGTATTGTATTAGCATGCAGTCGAAAATGTTTGTAGAAGGCTTCTTAAAAGAAACTCTTTTAATAATGAGTTTGACATTTTATTAACAAAACAACATATTTTTAAGGTTAACTAGAAATATTTAGTTTCATTACAATAAAGTTGATATTTTTTTTATTATTGTATTGATTTTTTTTTTTTTTCTAAAATCTAAAAACTGTCCTAGTCTAATTCCGTCATATATTCCAGGTATATTTATTATTCTGAATTTAAAAAATAAATATTTGATATGATTTCAGTTTGACATTAACATTTTGGTCACACTTTACAATAAGGGTTCATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6559
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067793 Nonsense 576 1017 17 29
ENSDART00000124755 None None 362 None 20
ENSDART00000130401 None None 362 None 11
Genomic Location (Zv9):
Chromosome 19 (position 27145721)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27075833
GRCz11 19 26660056
KASP Assay ID:
554-4956.1 (used for ordering genotyping assays)
KASP Sequence:
NNNNNTGGTCTTTCTCTCTCAGTGACACAGAAACACATTGTGAGGTCATG[C/T]AGGAAATTGTGGATCTCATTTTAGAGGTGATGTTTGCTCGTTGAAAACAT
Long Flanking Sequence:
ATGACAACACAGATGCTACCTTCAGTGACGATGAGGAGGAGCTGAACAACAAGGGTAAGATGCTTGCGGTAATGGTAACAACAAATGAACTTTAGACCAGCCAATTAAATAGAAGAGCACTATTTCAGCTGAGCCCATGTGCCCTGCTTTGTTGTTCAGGATCTAGATCAGTGAGTCTGGCTTAGAATGATGACCCACTTCTGTATTTTCAGCTCATTTCAGTGCCATCATGTTATGAACTCTTGTTTATCCCAAGGTAAAAAACGAGAGTTCAGATTTCATCAGCTCAAAGAAACGTACATTGACGAACCTTCTGACATCACTCCATTTGTTGATCAATTGGACGAGGCACTTAAAGAAAGGGTCCTGCAGCTGCAGAAGGGGAGGTGAGACACAGGATTAATGATAGTATTGTAGTTGTATGAAGGCCTCTATTGCTTAAGCCTGATTTGTGCTGGTCTTTCTCTCTCAGTGACACAGAAACACATTGTGAGGTCATG[C/T]AGGAAATTGTGGATCTCATTTTAGAGGTGATGTTTGCTCGTTGAAAACATTTTAGTTTGTACTTTCAATATGGCTGGCATACAAATGTATTTTTCTTTTTTATTTAGGAGGACTTTGACTCTGAGCAGATGTCCACTCTGGCTTCCTGTCTGGCTGAACTGTTTAAGAGTCACTTCAGAGGAGATGTGTTGCCTGAGGAGATCACAGAAGAGTATGTTTCTCTCTGACTTCCCGTCTAGTAGGATGTTAACTTTTTGTTTTTGGTTCTTGTCTGCATTGTGTCCTGCTCCTACTTCCCATGTTGCCCCGTTCATTTTTCTTAATGCTGATTAAGGCTAATAGGTTGCTGTGTGTATCTGTGTGTGCGCTTGTGTTTGCAGGTCACTGGAGGAGTCTGTCTGTAAGCCGGTGTGTCTGATCTTCAGGAACTTGTGTCAGATGCAGGAAGACAACAGTGGCTTCTCTGTTCTGCTGGACCTGCTCGCTGAGCTCTACCAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43290
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067793 Essential Splice Site 748 1017 21 29
ENSDART00000124755 Essential Splice Site None 362 12 20
ENSDART00000130401 None None 362 None 11
Genomic Location (Zv9):
Chromosome 19 (position 27150871)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27080983
GRCz11 19 26665206
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTAGTGGCGAGCTCCTCAACATGATCGTGGCTGTCATTGACTCAGCACAG[G/A]TTTCAGATATATAACTTTAGCAGTGATTTATATTCAAGATGATTTTTCAT
Long Flanking Sequence:
GATGTCCTAAATAATAATGTCAAATAACACACATTTCTCAAAATGGATATATCTGGTTTTGCAACGAAACTCTACATATATAGATGGATGGATGGATAGATGCTCAATAGTGCTCAACACAACAGCTGCCTGTTTTTCTGTTCATTATAGATCATGGAAATTTAGCTTTTTAGTCAGAAATAGTCAGGTAGAGTTTAACATGCAGCTTAGAGTGGAAACCCTGGGTGTAAATCTAATTGGGTGGGAAGTTTTCTTTGCAGTGTAATTGAGAAAAAAGATCAGAACATCTTAAAAATGTGTTAATGGCATTCAAATATTGGTTTTGTCTGATTATAACAGATTGCTTTAGCAGAGTTTCAGTGACTTTAACGTGTTTTTTGTGTCTTGATATGAACAGGCCTTTAGTCTTTCTGTGTGTTTGTGTCGTACAGTTTCCAGATGAGACTCTTCGTAGTGGCGAGCTCCTCAACATGATCGTGGCTGTCATTGACTCAGCACAG[G/A]TTTCAGATATATAACTTTAGCAGTGATTTATATTCAAGATGATTTTTCATTGAAATTTCAAATAACTTTGTCCTCTTGTTTTTGCCTCATAGCTTCAGGAGCTTATGTGTCACGTGATGATGGGGAATCTGGTCATGTTTCGTAAAGACTCAGTCCTCAACATTCTCAGTAAGTTCAGGGATTGCAGGTTAAGGTCAAATTGTGTTATTACACTAGGACTGGGCGATATGAGAAAAAAAAAATCTGTTTAATTTGATGTCAGCAATTATTACTCTAAAATGAAACCGAATTGATATTTTAATGGTAGACTTTTGCTTTTAAGGTAAAGTTTAATGTTCATTTAAATGGCTCTTTCATTGTCAGAACATGACAAACACTACCTTTATATTTTATGATGGTAAGTATGTGAGTAAATTTGAAATCGTTCGGCTGTTTTTTTTTTCATAACAAAATAGTTTGTTTACACTTTACAATAATTAGTTAGTGTTCGATAATGCATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14360
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067793 Nonsense 882 1017 25 29
ENSDART00000124755 None None 362 16 20
ENSDART00000130401 None None 362 None 11
Genomic Location (Zv9):
Chromosome 19 (position 27155020)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27085132
GRCz11 19 26669355
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGAACATATTAAAGCCCTGCTCATTAAGAACAACAACATGCCTCGCAAA[C/T]GACAGAGGTAATRGCAACCCTTGAGCTAGTTTAACGCCCTCTTGTGACCT
Long Flanking Sequence:
CTGCGAGTGAAAATTAAGCCTCGCCCGCTACTCAATATTCTGTTTCACTTGAAAATACTATCATCATGCTGTAATAAAAGTCTTCAGCAAATTCTGATTCACACTACTTTGAAGCAGATGCAGAAATGGGTTTTTCCATGGGTGTTAGTTTGTCTATGCTCCAGTTCAATCTCTGGTCCATGTTAATTCTCACTTTATGCACTTTGTATTATAAAATCATTTCAGTATGCTTTGTTTTCAAGTCTAGAACAAAAGTCAGCTGAAGTTATACAAAAAAAGCTGATTGTGATTTCTAGCCAGTCAGCCTGTGCATCTATAATATTTCTTCATTGTGCTTAAGGCCGAGTGAGGAGATGGTGAAGATGGTGTTGAGTCGACCGTATCACCAGGAGGATCAGTTCACCACCAGCATCCTCCGGCACTGGACAGCCAAACACGATGACCTGCTGGGAGAACATATTAAAGCCCTGCTCATTAAGAACAACAACATGCCTCGCAAA[C/T]GACAGAGGTAATGGCAACCCTTGAGCTAGTTTAACGCCCTCTTGTGACCTCAGAACTGAAATGTGGGTTTTGAAGGCCTCGGGGATGAGGACACAAGGGTTACAGGTTCAAGCTGAAGCACATTGACTGTAGGGTCGGTTATAGGCCTTGAGAAAAATGAAAAACATTTGAATGTTTGCACTATGAAGTTAACCGGTATAATGAAAACACAAAGATCTTGCCAGTAGGTGATATTTTGGTTTTCCACCTACAGATTGTCATGACTAGTAAGTTGTATAGTTTTAAGAAGTATTGTAATAGCGCCCCAGATTTAATCCTTTGATATATTTTACAAATCTATTATTACAGTTCTTTAGTTAAGTAAAATATTCTATTGTTGGACTGAATAATATATTGTTTGAGCATCAGTATCACAATGTGCGTGTCCGCAATAGTCACAATGCAGGACATGCGGTGTTGAGTTGGGTTTATAGTTGATCGTCAATTGAGAATACATGAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29217
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067793 Essential Splice Site 884 1017 None 29
ENSDART00000124755 Essential Splice Site None 362 None 20
ENSDART00000130401 None None 362 None 11
Genomic Location (Zv9):
Chromosome 19 (position 27155029)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 27085141
GRCz11 19 26669364
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTAAAGCCCTGCTCATTAAGAACAACAACATGCCTCGCAAACGACAGAGG[T/G]AATGGCAACCCTTGAGCTAGTTTAACGCCCTCTTGTGACCTCAGAACTGA
Long Flanking Sequence:
AAAATTAAGCCTCGCCCGCTACTCAATATTCTGTTTCACTTGAAAATACTATCATCATGCTGTAATAAAAGTCTTCAGCAAATTCTGATTCACACTACTTTGAAGCAGATGCAGAAATGGGTTTTTCCATGGGTGTTAGTTTGTCTATGCTCCAGTTCAATCTCTGGTCCATGTTAATTCTCACTTTATGCACTTTGTATTATAAAATCATTTCAGTATGCTTTGTTTTCAAGTCTAGAACAAAAGTCAGCTGAAGTTATACAAAAAAAGCTGATTGTGATTTCTAGCCAGTCAGCCTGTGCATCTATAATATTTCTTCATTGTGCTTAAGGCCGAGTGAGGAGATGGTGAAGATGGTGTTGAGTCGACCGTATCACCAGGAGGATCAGTTCACCACCAGCATCCTCCGGCACTGGACAGCCAAACACGATGACCTGCTGGGAGAACATATTAAAGCCCTGCTCATTAAGAACAACAACATGCCTCGCAAACGACAGAGG[T/G]AATGGCAACCCTTGAGCTAGTTTAACGCCCTCTTGTGACCTCAGAACTGAAATGTGGGTTTTGAAGGCCTCGGGGATGAGGACACAAGGGTTACAGGTTCAAGCTGAAGCACATTGACTGTAGGGTCGGTTATAGGCCTTGAGAAAAATGAAAAACATTTGAATGTTTGCACTATGAAGTTAACCGGTATAATGAAAACACAAAGATCTTGCCAGTAGGTGATATTTTGGTTTTCCACCTACAGATTGTCATGACTAGTAAGTTGTATAGTTTTAAGAAGTATTGTAATAGCGCCCCAGATTTAATCCTTTGATATATTTTACAAATCTATTATTACAGTTCTTTAGTTAAGTAAAATATTCTATTGTTGGACTGAATAATATATTGTTTGAGCATCAGTATCACAATGTGCGTGTCCGCAATAGTCACAATGCAGGACATGCGGTGTTGAGTTGGGTTTATAGTTGATCGTCAATTGAGAATACATGAGATTTGTGGAG
Associated Phenotype:
Not determined