ZMP
atic
Ensembl ID:
ZFIN ID:
Description:
bifunctional purine biosynthesis protein PURH [Source:RefSeq peptide;Acc:NP_001076265]
Human Orthologue:
ATIC
Human Description:
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [Source:HGNC Symb
Mouse Orthologue:
Atic
Mouse Description:
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Gene [Source:MGI
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa39534 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa19406 | Nonsense | Available for shipment | Available now |
| sa4826 | Nonsense | F2 line generated | Not yet available |
Mutation Details
Allele Name:
sa39534
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022307 | Essential Splice Site | 126 | 590 | 5 | 15 |
The following transcripts of ENSDARG00000016706 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 4381454)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 4794495 |
| GRCz11 | 1 | 5492300 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAGGTTCTCCAGTTGACATGTTTCACCATTATTCCCATAATCCTCTTTA[G/T]GTGGTGTTACGCTTCTTCGAGCGGCAGCTAAGAATCACGCTAGAGTCACC
Long Flanking Sequence:
TTGTGTATTGTGATTCAGTTTCTAGAGAAACAGATTATTAAATGAAGAAAACAGAGGGCGTGGCCTGTTAATTTATTTTTTTGCTGCGAGCTGATTGAATGTAGTAAAGTAGGCATGTCATTCAGAAACATCACGATAAGAGTTTCGGGTTTCGAGTTACAAGCTAACAGACACCTCCCCCTCGACATTTCTGTTTGTTGTCAAAACAGTTGGAGGGGTGTGGTTAAGTTTTTTAGCCACACCCAATACCTTAGACTAACCTATTCTGAAAACAAACAGGAAGTACATTTTCAGATTTTGATTTTAGATTACAAGGGCAAAGTATTTTTTTTTCTCCTTAATGACACGCACAATTGAAATGTTCACCGCAAAACTAGCATTGTGAGCTCACAAAATCATATGGTTAGTTTTAATTTCATCTGTACTTCAAACATGTCTTGACTACCTTTGTGAGGTTCTCCAGTTGACATGTTTCACCATTATTCCCATAATCCTCTTTA[G/T]GTGGTGTTACGCTTCTTCGAGCGGCAGCTAAGAATCACGCTAGAGTCACCGTCGTCTGCGATCCATCCGACTACAATGTTGTGGCCAAGGAAATGGAGACCTCTGAAATCCACGACACCACAATGGAAACCCGCAAAACTCTCGCGCTCAAGGTAAACGCGTGGGGATTATTGACCCACTAACCTTTGTGCACATGTGAAACTCTTTGATCCAAAGGCGAGTTTAATAAGTGAGGCAAGCGGCCGCTTGGGGCCAAATTTCTCAAGAAATTTGGAGTTCCCTAATAAATAGCTAGAAGTATACATTTTATTTTATAAATAAATAAATGAATATGAATAAACCAACATTGTTTCCTCATATTTAGTAAAGTCTGGGGTCTAATAAAATAATTTATCATAATTATTACATCTGTGCAAATTTGTCCCCCACCTCTGAATAATGGAGCAGTTCAGCAGTCAAATTAGATGAAGATTTAGTTTTAAAAACGAAATGATTTATTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa19406
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022307 | Nonsense | 184 | 590 | 6 | 15 |
The following transcripts of ENSDARG00000016706 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 4384347)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 4797388 |
| GRCz11 | 1 | 5495193 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATGAATTTGTATTTGTAATTCGTCAGGCCTTCACGCACACCGCTCAGTA[C/A]GACGAGGCCATCTCTGATTACTTCAGACGTGAATACAGTCGAGGAGTTTC
Long Flanking Sequence:
CGTGGCGCAACGCCTCAAAACGACTTTTGCGCCAAGCTGAAACAAGCAAACAAGTATTGCGCCGCGCGTTGCGCCACACTGCGCCGGGTGTATGATGGGGCCCTAAGTGTTTCTCTTCTTTGTATTAGTCACCCGTCTCTCTAGACCAGTGTTTCCCAACCCTGTTCCTGAAGGCACACCAACAGTACACATCTTCAACCTCTTCCTTATCAAACACTCCGGAATCAACTCATCAGAACATTAGAAGAGTCTCCAAAACCGGAAGTTAATGGGTCAGATGAGGATGACATCCAAAATTTGTACTGTTGGTGTGTCTCCAGGAACAGGGTTGGGGAAATACTACTCTAGACATCCACTGTATCGTCATTAGTGAACTCATTTATTGTTTTATTTTTATTTATTTAGAGCTCTAAATTCAGTCCAGTTACTTATAAATAATTTTTTTTAGTGTATGAATTTGTATTTGTAATTCGTCAGGCCTTCACGCACACCGCTCAGTA[C/A]GACGAGGCCATCTCTGATTACTTCAGACGTGAATACAGTCGAGGAGTTTCCCAGCTTCCTCTGCGTTACGGGATGAACCCACATCAAGCACCAGCTCAGCTCTACACTACACGACCAGCACTTCCGCTCACAGGTAAATATGGCCACACATCAGAGAGCTATTCAACCATGAATGCCATATTAATTTGAATGTTTGTTTCAGTGCTGAATGGATCTCCTGGCTTCATTAATCTGTGTGATGCTCTGAACGCCTGGCAGCTGGTCAGAGAGTTGAGGAAGGCTCTCGGTTTGCCAGCCGCCACTTCATTTAAACACGTCAGTCCTGCAGGTATGAACACAAACATGCTCCAAGGATCATCATAAAGCCGCCTTTCCATTGCACACACATTTGGACACGACTGTCTGAATACGCCCTCTTGTGGCAGCCGCACAGTATTTTCAGTGTTGTCGTGCACCACGGGGGAGCTGATTCTCACGGTGTCCGAAATAAAGGAGGGCAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa4826
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022307 | Nonsense | 464 | 590 | 13 | 15 |
The following transcripts of ENSDARG00000016706 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 1 (position 4389966)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 4803007 |
| GRCz11 | 1 | 5500812 |
KASP Assay ID:
554-3561.1 (used for ordering genotyping assays)
KASP Sequence:
TCTCGTATCCACTGCACCCGGCTGGCAGGAGACAAGGCTGATAACTGGTG[G/A]CTCAGGCACCATCCAGGAGTGCTCAGTATGAGGTTCCGCRGCGGAGTGAA
Long Flanking Sequence:
TGTAGTTCAATAGTGCATCTAAGCTGTCTTTAGTATAGTGCAATTTGAATACATTTATTTTACCACTAATTTTGTGTTCTTTTTGTCTTAAATTTAATACTTAATGGTCCTAAAAAGTCATCAATTTGACATTATAATATCTGCAGAAACCCTGGTTTAGTCACTGGGATTTGATTGGACTGTTGAAATACTCTTTTTGTGTTAATGTGAAGGATCTTCTAACACAGTTGATGTGATTTTTGTGTTAAAGCTCTCTGAGAGTGCTCTGCGAGACCTCATCGTTGCCTCCATCGCTGTAAAGTACACCCAGTCTAACTCTGTGTGTTATGCTAAGGATGGGCAGGTAAACAAAAGTTTATACATTTTATATATATAAAGGAAATTCAGTATAAAAATATTTGTTGTCTGGTGTGTGTTTGTTAGGTGATTGGCATCGGAGCTGGGCAGCAGTCTCGTATCCACTGCACCCGGCTGGCAGGAGACAAGGCTGATAACTGGTG[G/A]CTCAGGCACCATCCAGGAGTGCTCAGTATGAGGTTCCGCGGCGGAGTGAAGCGTGCAGAGATGGCTAATGCTATTGATCTGTATGTCAGCGGCACAGTTGGAGAGGTAGTCTATTTAAACATTGGTCATTTGTACTAGTCATACAGGGATATATTGAACTATTTAGCTGCTTCAGGATTGTCTACAACCATGCTTTCATAAGTAGCAACAAAAACTACAATGTCTAGACATGATGTAGACATTTTGTGAATGTAGTAAATTGTAACAGTTGTGGATCTATCTCTCAGAAACAGACGAGAAATGTGTGGATCATTTTCACCTCAAATGGAAAAAATAAATAAAACAAAAAATAAAAGTAGCAATGACAATTTGGGTGCAAGATGTGCTTAACCCTTACATCATTTACAAAAAATGTGTACAATTTTTGGATTCCACACTTATTTGGTCTTGAAGAACAGTTATTTTATAAAACCCAACATTTTCAACTAAATGCTTCGATG
Associated Phenotype:
Not determined