ZMP

pla2g12b

Ensembl ID:

ENSDARG00000015662

ZFIN ID:

ZDB-GENE-040426-2771

Description:

group XIIB secretory phospholipase A2-like protein [Source:RefSeq peptide;Acc:NP_998595]

Human Orthologue:

PLA2G12B

Human Description:

phospholipase A2, group XIIB [Source:HGNC Symbol;Acc:18555]

Mouse Orthologue:

Pla2g12b

Mouse Description:

phospholipase A2, group XIIB Gene [Source:MGI Symbol;Acc:MGI:1917086]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa659	Essential Splice Site	Confirmed mutation in F2 line	Not yet available
sa10863	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa659

Status:

Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000128494	Essential Splice Site	197	235	4	4

Genomic Location (Zv9):

Chromosome 13 (position 4336679)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	4553408
GRCz11	13	4681994

KASP Assay ID:

554-0567.1 (used for ordering genotyping assays)

KASP Sequence:

ATAAYAAACTGGATGATCTSTGATAACTTTTCCTATTCTTTCTCCTGCAC[A/T]GCATGTGAGACCTTTGCAGACACCATGTACAACACTGTGTGGACTTTGGG

Long Flanking Sequence:

TGTAAAACGTGCCCAAGTAACTATATTTACGATCGTCAAAAATATGCACAGGGGCCTCCAGTGGATTTGTGAAAGCAAAAACTGTAAGAAGATGTAGCCCCTGGTACATATTTCTGGGTTCTCAAAAATGTAGCCCTGGGTACATACAATTGAAGTCAGAACTATTAGCTCTCCTTACTTATTATACCCCTGTTTATTTCCCCCAATTTCTGTTTAACAGAGAGATTTTTTTCAGCACATTTCAAAACATAATAGTTTTATAACATATTTCTAATAACTGATTTGTTTTATCTTTGCTATGATGATAGTACATAATAAGTTATTGTATAACAGTGTTTTGTCTAATAATTTAGACTTCAACTGTCTCCCCAATGAGCTTGGGTTGCTTAAAACAAGGGAAAGCAAACCAAATCAGTTCTGATATGTAAAAAAAAGGGATTAACATTTGTAATAACAAACTGGATGATCTCTGATAACTTTTCCTATTCTTTCTCCTGCAC[A/T]GCATGTGAGACCTTTGCAGACACCATGTACAACACTGTGTGGACTTTGGGCTGCAGACCCTTCATGAACGGCCAAAGGGCGTCCTGCTATTGCGAAGGAGAAGAGAAGGATGAGCTCTGAAGACCAACAAAATCACAAAACACACCACCTTCAGCACATATAAACACTTCATAGCTTTAAACTATACCACACAAGGCACGAGTCACATTCAAACAAGTCACATTTCACTACAAACATTGAGTAGAAACTATTGATCGACATTAATTTGAAGTGAAATGTGACCTTCACACGTTGTGGAGATTCATCCACTAACCCTTGAACTGGTGCTATTGGATTTTGTCAGACAAGAAAAAGTTTATATGGTATATGGGTGTCGTTATCGCATATGTATTGTGTGTGTGTGTGTGATTGTGTATAGGTTTCGCACACAGAAATCTGATATATGGCAATATATGCAAATTTCATATATAACATACAAGTTTATATTTGAATTTCACATA

Associated Phenotype:

This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.

Stage	Entity	Quality	Tag
Larval:Day 5 ZFS:0000037	yolk ZFA:0000084	increased size PATO:0000586	abnormal PATO:0000460
Larval:Day 5 ZFS:0000037	yolk ZFA:0000084	necrotic PATO:0000647	abnormal PATO:0000460

Mutation Details

Allele Name:

sa10863

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000128494	Nonsense	210	235	4	4

Genomic Location (Zv9):

Chromosome 13 (position 4336720)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	4553449
GRCz11	13	4682035

KASP Assay ID:

2260-5968.1 (used for ordering genotyping assays)

KASP Sequence:

CYCCTGCACWGCATGTGAGACCTTYGCWGACACCATGTACAACACTGTGT[G/A]GACTTTGGGCTGCAGACCCTTCATGAACGGCCAAAGGGCGTCCTGCTATT

Long Flanking Sequence:

ATATGCACAGGGGCCTCCAGTGGATTTGTGAAAGCAAAAACTGTAAGAAGATGTAGCCCCTGGTACATATTTCTGGGTTCTCAAAAATGTAGCCCTGGGTACATACAATTGAAGTCAGAACTATTAGCTCTCCTTACTTATTATACCCCTGTTTATTTCCCCCAATTTCTGTTTAACAGAGAGATTTTTTTCAGCACATTTCAAAACATAATAGTTTTATAACATATTTCTAATAACTGATTTGTTTTATCTTTGCTATGATGATAGTACATAATAAGTTATTGTATAACAGTGTTTTGTCTAATAATTTAGACTTCAACTGTCTCCCCAATGAGCTTGGGTTGCTTAAAACAAGGGAAAGCAAACCAAATCAGTTCTGATATGTAAAAAAAAGGGATTAACATTTGTAATAACAAACTGGATGATCTCTGATAACTTTTCCTATTCTTTCTCCTGCACAGCATGTGAGACCTTTGCAGACACCATGTACAACACTGTGT[G/A]GACTTTGGGCTGCAGACCCTTCATGAACGGCCAAAGGGCGTCCTGCTATTGCGAAGGAGAAGAGAAGGATGAGCTCTGAAGACCAACAAAATCACAAAACACACCACCTTCAGCACATATAAACACTTCATAGCTTTAAACTATACCACACAAGGCACGAGTCACATTCAAACAAGTCACATTTCACTACAAACATTGAGTAGAAACTATTGATCGACATTAATTTGAAGTGAAATGTGACCTTCACACGTTGTGGAGATTCATCCACTAACCCTTGAACTGGTGCTATTGGATTTTGTCAGACAAGAAAAAGTTTATATGGTATATGGGTGTCGTTATCGCATATGTATTGTGTGTGTGTGTGTGATTGTGTATAGGTTTCGCACACAGAAATCTGATATATGGCAATATATGCAAATTTCATATATAACATACAAGTTTATATTTGAATTTCACATATAGAAAAATCAATGGTTCATTCCACTGTGTCAGCCTCTAAA

Associated Phenotype:

Not determined