Busch Lab

ZMP

zgc:76988

Ensembl ID:
ENSDARG00000015352
ZFIN ID:
ZDB-GENE-030131-2184
Description:
Large subunit GTPase 1 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q6NY89]
Human Orthologue:
LSG1
Human Description:
large subunit GTPase 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25652]
Mouse Orthologue:
Lsg1
Mouse Description:
large subunit GTPase 1 homolog (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:107236]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa2609 Essential Splice Site F2 line generated Not yet available
sa21946 Nonsense Available for shipment Available now
sa11790 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa2609
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023867 Essential Splice Site 117 640 3 14
Genomic Location (Zv9):
Chromosome 11 (position 35031036)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 33968109
GRCz11 11 34230541
KASP Assay ID:
554-3168.1 (used for ordering genotyping assays)
KASP Sequence:
CTAAAGAAACTCCATGAGGAAAACAAACAGCTTCTGCGAATCCCCCGAAG[G/A]TATTCTGATGTCTTATAATATGCATTTTTTCCTTACCTATATTAAAGTTT
Long Flanking Sequence:
GTTAGATCGATTGCATCTCCATAAAATATAATAAACAATATATTACATTTTTAGGGGTCCCCCCCCAACAGATCTTAGTAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTATTGACACAAAAAAATCGCAAAAAAAAAAAAAAAGAAAGTGGTTTATTAAAAATAATAAAGAAATATGGTTTAATTTAAGCTGTGGTGATTTAAGTACTGAGTAATTAAAATTAATTGAAAATTGACCATATGGGTTAGCATTTATTTATGCATAATTTACTGTATTATTGTAGTAAGTACATGTAATATGTAACAAGGACACAAAACTATAGCACTGTCAGCTATAGAACAATATATAAAGATATGTCATTGTTTTGCAGAGAAGCTCAATATAAAGTTTGTCCCAGCTGAAGCAAGAGCTGGCTTGCTTTCCTCTGAGGAGTCCAGGCGGCTAAAGAAACTCCATGAGGAAAACAAACAGCTTCTGCGAATCCCCCGAAG[G/A]TATTCTGATGTCTTATAATATGCATTTTTTCCTTACCTATATTAAAGTTTATCATGGATGCAAAACAATGCAAAAGCAGATGTTTTCAACATTGTGCTTTGTCTCCTCAGACCTCCTTGGGATGAGAGCACAAGTCCTGAAGTTCTACAGCAAACTGAGAAAGACAGTTTCCTCACATGGAGAAGAGATCTGGCTCGGTGAATGACTTAAATGTTCAGTCCAAATATTAGCAAATTAAGAAAGATGATAATGTTTGTGACTAAATGCACTTTCTGTTATAGGTTGGAAGAGGAGCAGAAGTTGATTCTCACCCCTTTTGAGAGAAATCTCGATTTTTGGAGGCAACTGTGGAGAGTTATTGAGAGAAGGTGAGCTTTTGTTTGGCTTGTACTGAAGTTGTTTTATTTGTATATTTTACTATCTGGTCACACTAATGATTGCATATTAGGGGCTGTTTCTGTCTGAAACATATATTTTCAATGTTTAAATGCATCCACAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21946
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023867 Nonsense 376 640 9 14
Genomic Location (Zv9):
Chromosome 11 (position 35035719)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 33963426
GRCz11 11 34225858
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCATCAGAACTGTTAATATTCTAACTCTAAATTCTCTGCAAGGTTGGATA[T/A]CCAAATGTTGGGAAAAGCTCCACCATCAACACCATCTTTAGGAATAAAAA
Long Flanking Sequence:
TGGAGAACACAGATACACACACATGTAATAATGAGTCTTAGTCAAGTTTCTAACATATAAAGCTCATCTAAAAATGAATTTCCATTACAAAAACCAATTCATTTAGGATCACTGCAATGTTGCAAAGGGTTTGTTCTGACCTTGGAACTGGAAAATCAAGCACAAGTTTGTGTTACTTAAAATGAAGAACTTTTGTTTATTGAACTGTTGCTGCTGTATAAAATCAGTATTACATTTGTGATCTGAAGTTTTGTAAAAAATCATTGTGAAATATTATAAACATCATATCTTACAAATGTAAAAAAACTCATTGAAGCATATTTTATGCTTTTCTTAACTCTTGATTGTTTTATTTACAAAGCTGGTGACATTCTCAATAATACTATCTCTCACATCATTAGGATTTTATCACAGATGATTCTACAATATATCAAACATGTTTGCTGTTTTCCATCAGAACTGTTAATATTCTAACTCTAAATTCTCTGCAAGGTTGGATA[T/A]CCAAATGTTGGGAAAAGCTCCACCATCAACACCATCTTTAGGAATAAAAAAGTCTCAGTTTCGGCAACACCTGGACACACAAAGCACTTTCAGGTGAGTTTTTTCAAATTATTATTAAGGAAGTAGAGTTTTAAAAATGAATCCTTGAAATTGTTTGTCCCTTCAGATTTAGAGGCTTTTTATTTTAAAGTAGCCAACTCATTGTATACCAATAGCTTCCAAAACAAAGTGATGTAAAGCATGTTGTAATTACAAGTTCAGTTTATTCTTTCTGACTTCTGGTGTTTGTTTGCCTATATGTTTCAGACTCTGTTTGTTGAACCCGGTCTTTGCCTGTGTGATTGTCCTGGACTGGTCATGCCTTCATTTGTGTCCACCAAAGCTGAGATGATCTGCAGCGGGATCCTACCCATCGATCAGATGAGAGATCACGTGCCAGCCATCTCTTTGATAACCTTTTACGCTGCATTGATTGTGACAGTTGCATTTTTAAACTTGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11790
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023867 Nonsense 469 640 11 14
Genomic Location (Zv9):
Chromosome 11 (position 35036401)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 33962744
GRCz11 11 34225176
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CACAAATACGTATGTCAGAATATCCCTCGAAATGTGCTGGAGGGSACTTA[C/A]GGAATCAACATCATCAGACCGAGGGARGACGAGGACCCTGATCGGCCGCC
Long Flanking Sequence:
ATTTTAAAGTAGCCAACTCATTGTATACCAATAGCTTCCAAAACAAAGTGATGTAAAGCATGTTGTAATTACAAGTTCAGTTTATTCTTTCTGACTTCTGGTGTTTGTTTGCCTATATGTTTCAGACTCTGTTTGTTGAACCCGGTCTTTGCCTGTGTGATTGTCCTGGACTGGTCATGCCTTCATTTGTGTCCACCAAAGCTGAGATGATCTGCAGCGGGATCCTACCCATCGATCAGATGAGAGATCACGTGCCAGCCATCTCTTTGATAACCTTTTACGCTGCATTGATTGTGACAGTTGCATTTTTAAACTTGATCGCAACACATACACTACTGTAAAGCTGCATGATCCATTTTACTAACCCTAAACATTTTGATTGGTAGTACGTAAGAATTTTTGTTATCAATGAGTTACCAAAAATCTGAAAAGTTTGGATTTTGTCCTTAGCACAAATACGTATGTCAGAATATCCCTCGAAATGTGCTGGAGGGGACTTA[C/A]GGAATCAACATCATCAGACCGAGGGAGGACGAGGACCCTGATCGGCCGCCTACCTATGAGGAGCTGCTTATGGCATACGGATGTCAGTTCACTTTGCACAATGTACACATCACATAGGTCACAATTGTGACCGTCTTTTTTCTGGAAGCTCTAAAAATGTGTTGTTGGCTGTAGGCAAGACATTTTTTAATGAAAAATTAGATTGCTTTGAACCGTTTACATACTTCCTGCTTGCACATCTATCAGATGTAAGTAGTGAAAATTTGTTGAAGGTTACAGTTGTTAACGGTAGCATAACAATTGGTAGCACTTTAGAATAATGGTCTATTAGTTAATGTATTTACTAACATTAAGTATGTATAATCTTGTTGTGCATTTATTAATTGTAGTTTAACGTTAACTAATTCATTATTAAATTACCCAAATAAATGGATTGCTAATAATTTGTTCATGTTAGTAAGTTCATTAACTAACAATAAGTGATGAACCGTTTATTTAAA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa27814
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023867 Nonsense 556 640 13 14
Genomic Location (Zv9):
Chromosome 11 (position 35038680)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 33960465
GRCz11 11 34222897
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTTCCAGCCTCAGCACGCCAAGTTTGCCATGCGGATAACAGAAGCCGAA[C/T]AGATCGATGGCAGTGGTGGCAAACCATCAAAAGTGAAACGCATAGAAAAC
Long Flanking Sequence:
GCTTTATGACAGCACACGGACAGCCAGACCAATCAAGATCTGCTCGATATGTTTTAAAAGACTATGTCAGTGTAAGTGCACCTTTATTGTAGGGACTACTAGCTCTGAGGCATTTTTTAATTTAAGATATAGTTTTGTCAAATCGCTCACAAGTGGATAACATTAAAATAATTGTGTAAATGATCTTAAATGTTTTGAGTTTTTTACAAATGGTTGACAGGAATATGAACTAAAGAGATTGGATTGAGGATTAAACACCAGGTGTAAACAGGAATGTGTCTTCAATGTGAACTATTAATCTAAATGAACAAAATGCATTTTAATTCCAGGTGTAAACAGGGCCTGGATATTATGATAAAAAAATAATTGGAGATGCTAATTCGTTCTTACCTGAATTGTTGCAGGGCAAACTCCTCTACTGCCATCCTCCACCTCACATCGATCCTGAAGACTTCCAGCCTCAGCACGCCAAGTTTGCCATGCGGATAACAGAAGCCGAA[C/T]AGATCGATGGCAGTGGTGGCAAACCATCAAAAGTGAAACGCATAGAAAACACAGTGGATAAACAGTTTTTTCATCAAGTAAGATTCAACCCATCAGTGCTTTCTGACATTGTCAGGCTACTTAATTGCACAATATAAAATATTTGTTCATTAAAATATCTCAAAACCTCATAAACAGTGTTATATTTTGCTGACCTATAATTGATGAATGTTCAAATACAGAGAAATAAGCAATTTGGACATCATAAATCCACCATTTCCGGTTCGGTTTTAAAGAAAATAGAAGAACATCAATGATGCTTTAATATGTTGTATGTTTTATTAGACTGCACATTGAAGCATCCTAAAATGTAATTTAGTCTGATAAAACAGCGCTGCTGCTTCTCCACAAGATACAGTAATATCTAGCTGCAGACTCACTCACGTTTCAGGCACACAACATCCAGCACACGATCTAGGCAAACCATGTATTGTTATGACCGATGTTATTGTAATTAACGT
Associated Phenotype:
Not determined