Busch Lab

ZMP

si:dkey-261o10.2

Ensembl ID:
ENSDARG00000014592
ZFIN IDs:
ZDB-GENE-060404-6, ZDB-GENE-091118-31
Human Orthologue:
DENND1A
Human Description:
DENN/MADD domain containing 1A [Source:HGNC Symbol;Acc:29324]
Mouse Orthologue:
Dennd1a
Mouse Description:
DENN/MADD domain containing 1A Gene [Source:MGI Symbol;Acc:MGI:2442794]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa37235 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa16575 Essential Splice Site Available for shipment Available now
sa14051 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa37235
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055336 Essential Splice Site 42 1007 3 25
ENSDART00000143151 Essential Splice Site 42 511 3 20
Genomic Location (Zv9):
Chromosome 21 (position 7938694)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 8346245
GRCz11 21 8438784
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCAGGACTAGAGGTGCGCAGAAGTTTCCCCGACACATACACTGAACAGG[T/G]TTGTGCTTCTTAATTTTTTTTCCTCTGTGTTTCTCCAGGGATGTTGAGGT
Long Flanking Sequence:
CAGAAGCCCTGAGTTTTGATATCTTAAAGAGCGAGTTGGATTGTAGAAAGACAGAAGGTTGGTTAGATAAACAGGAGCTAGATTATTTAAAGCTTTATATGAAACAAGCAATATTTTAAATTCAATACGAAATTTAACAGGCAGCCAGTGTAAGGAGGATAAAATTAGGGTGATATGATCATATTTTCCAAACCTGGTAAGAACTCTGGATTTTGCATTTGCATTTTGTACTAGCCGAGGTTTGTTAATAGAGGATACTGGGCAGCCAGCAAACAGCATTACAGTAATCCAGCCTAGAAGTCATAAAAGCATAGACTAGCTTTATCATTATCATAATTTTATTTGTTAACATTCCCCAGATTTTTTGTACTTGCTAGGTAAATTGTGATGATATAGAAAAACACCTGTGTGTATGCATCTATTTAATAACTTTCAGATTTCTGTATTATTTTCAGGACTAGAGGTGCGCAGAAGTTTCCCCGACACATACACTGAACAGG[T/G]TTGTGCTTCTTAATTTTTTTTCCTCTGTGTTTCTCCAGGGATGTTGAGGTAGATCTCATAATTGTTGCTCACCTCAGTGATAATGCATTGAGCACCTGCTCTGACAGATGGAGTTTAAACCACTAGAGAGTCTGCGGTACCAAACACCCTCTGAAGGGGATTTAACCAAACTCACTCAAGATTGTGACTCAGGCTTACATATGCTTTCGCTGCGTCTGACTTCTGCTTATTCCCTCTTCTGTGAATGACACTATATCTAAAGTAGTCAGCAAAATCATATGCTGATGTAAATATTGTCTGCCAAAGAGCTCTGAAGGTGATGAGTGACTAGCAACTGTTTTCTCTTTTATTTATTGATATACATTTGAATTCATGCTAATCAGTGTTTCTGCACAGATAGGAGAACTCGTCCCAAAAAGAAGTAATAAAGGCTGCAATAACAATCACTTATCTACCTAAATATTTGTAATACAGTGGTCCCTTGTTTATCGCGGGAGTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16575
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055336 Essential Splice Site 488 1007 19 25
ENSDART00000143151 Essential Splice Site 488 511 19 20
Genomic Location (Zv9):
Chromosome 21 (position 7956056)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 8363607
GRCz11 21 8456146
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACTCCCTCACCTGGGACCAGAGGCGGCCAATCACAGTTCACTTTGGGCAG[G/A]TGGGTAAAAGAGATGTTGTGAATTCTTGTTAGATTRAAAAAGYGTATTGT
Long Flanking Sequence:
TCATGGCTTGAATTGTAATTTAATTAAATTTTTATTTTAAATAAAATTTTTATATTTTTATATATTTTTGTATTTTAAATAATAATTTTTAACTTTGATTTTCAAATCTTTTTAGTTATTTTATGTAATTGTATATTTTTATTTATTAGTTTGAGCGAATTTTGTTTTATCAGTGTGAGTAAACAGCAACAATTTCAAAAGATTTAAATGTGCAGTTTATAAGCAAATCTCTCATCCTCTGCAGGCCAAAGACCATGCCAAGATGGGCATCAAAGAAGTCAAGAGTCGACTCAAACAAAAGGTACTCATTTCAGTAAATAAATCAATTATTTATAAGTACTGCATAAACACACACCCATTCACTGTCACTGAATCTCTTGCAGGAGCTTACAGAGAACGGCTACTCAGAAGAGCCCGGGCCCACTCAGCTTCCCTCCACACAGAGCAAAGACTCCCTCACCTGGGACCAGAGGCGGCCAATCACAGTTCACTTTGGGCAG[G/A]TGGGTAAAAGAGATGTTGTGAATTCTTGTTAGATTGAAAAAGTGTATTGTGATGATAAACATGCAGTCTTGTTTAATTTATTATTTTTTTTCTTTATTCTTTAATGCGATCCACTCTATAAAGTGTAAAAAGATAAATCTTAGGCAATTTGACTGGAGTGCTGTTTAACCTAGATTTTTCTTAAATGCCGTTTTCTCAACTCTGCAATATTAGTTGCATGTTTATTTTGTTATTGAGAGGAAAAACTGCTGCACATATTGACTAGGATGATCATACCTGCCAGTTGTACTGGACACTTCCTGACCAGGATTCATTTATATTACTTTGCTCTCCAAGATTCATGCTTAAAGGTAATTATTGAATAGTAGTTTGACCAATGACTTTCAGGCATTGTACTTATTCAAGCAATCATGGCGCTTGGAATGTGGGATCTAAACAGAATGTTCAAAGTAATGCAAATATGCATTTATACAGTAATTAGATGTGTTTGTTTGAAGAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14051
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055336 Nonsense 833 1007 24 25
ENSDART00000143151 None None 511 None 20
Genomic Location (Zv9):
Chromosome 21 (position 7969790)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 8377341
GRCz11 21 8469880
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAAGACCAATGAGCCAAAYGAGGGACAGGAGCAGGACTTACTTAGCTTGT[T/A]GGATCCGTTGTGTGGAGCAACAAAGGATGAGGCCACMYCATCCCTTTCTA
Long Flanking Sequence:
TCTATCCTAAAAACTGTTTCAATTGTTTGTTCTCCAGCGGATGGAACTAAATGCTGGTGAGCGCACACGCACACTTCCCGTGCTTAAAACCACCAACCCATACAGCAAGCTCTGGAGTCAAAGGGAAGACCCATCCACCTTGCTTGGCCGGGAGTCACCATCCTGGGAGAGACCTCTTTCCGTTCCACCCTTAGAACCTTCTGATGTGCGCCCACCCAGCAAGGAGAGTTCAAATTCCTGTGCAGAGAAGACGGAAGGGGCTTGCATTACAATCCCTCGTCCCCAAGGTCGGAAAACACCAGAACCAGGTGCAGTGCTGGCTCCAGCGGTGACCCTGCTGCGCGGGGTTAGGCAGGCCTGTGACAAGGAAGGAGGAGTGTCTGCTGGAGGGCAGGAGTTTCGGCAGGCATTAAATATGTCTCCTCAAGCACAAACTCAGGTGGACCTGTTGAAGACCAATGAGCCAAACGAGGGACAGGAGCAGGACTTACTTAGCTTGT[T/A]GGATCCGTTGTGTGGAGCAACAAAGGATGAGGCCACACCATCCCTTTCTAAACCTCCTGTACCTCCTAGACCGAACCCCCCAAACCTTGCCAACTTTCCCCCTCCAGTGTCTATGAACCCTTTTACCCAACCACCGCAGTACCCACCTCAAAGGCACTATAGTCCTGTCGTCCCAGGTAACCCTTTCACCCCAGCCTTCATGAATCCCCCAGGTGCCAACTACTTCCCCGCCTCAGGCAGTCCATACGCAGTATTTAATCAGGCATCCACTGTGGGTGTGACCCCAACTGGAGGGGCGTGGCCCATTGGACGTGTTCTTCCAACCTCCAGCAGTAGTGGATCTCTTTCAACCCTCTTAGACTCATCTTCTCCGGCTACTTTGTCACAGCCTGTGCAAGTCTCCACAGATGCACCCAGTGACCCATTCAGTGACCTTCTTACCATGGCAACTACACCAACAATAATGGCCACGCCCCCCAAAAAGAAGGTGGAGGACTTGC
Associated Phenotype:
Not determined