ZMP
axin2
Ensembl ID:
ZFIN ID:
Description:
Axin-2 [Source:UniProtKB/Swiss-Prot;Acc:P57095]
Human Orthologue:
AXIN2
Human Description:
axin 2 [Source:HGNC Symbol;Acc:904]
Mouse Orthologue:
Axin2
Mouse Description:
axin2 Gene [Source:MGI Symbol;Acc:MGI:1270862]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa40180 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa40181 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa45159 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa40180
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000019803 | None | None | 268 | None | 3 |
| ENSDART00000020575 | Nonsense | 456 | 812 | 6 | 11 |
| ENSDART00000124707 | None | None | 321 | None | 3 |
The following transcripts of ENSDARG00000014147 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 3 (position 56627761)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 55388462 |
| GRCz11 | 3 | 55640071 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCTTTCCAGAGTCCTCAAGACCCCTGGCTGTCAGTCTCCAGGATTGCTT[C/T]GACATTCCCCACGCTCTCGCTCTCCTGAACAGCGTCCCCTGCCTCGGGGA
Long Flanking Sequence:
TGTCTGCTCTTCTTGCTAATCTGTATCTCTCTCTGGTTGTGCAGAGGACGCGGCGGCCACCTAAGGAGATGACTCCCGTGGAGCCAGCAGCCTTTGCAGCACAGTTGATAGCCAGACTGGAGCGACTGAAGCGGGAACAGGAAACCATGAGCTCCCTGGAGGAGAGACTTCAACAGATTCAGGAGGTCGGTGTTGCTAGAAGTTTGTAAGAATGTTGACACTGATAATAGCGTGAACATTAAAAGAAGGTCATTCGATAACAGGCCTAATTGTGTCTCAACTAAACAACTGTTTGCAAGCAATTAGTTTTTTGTAAAATAAGTATTTGTGTGCGGTTGTAGGAGGAAGAGCGAGATGAATCTGAGATGTCTAGTAGCAGTGCGTCCCATTCTCTGCCTTTGCTCCCTCCTGGCACTTGTGAGGAGGATCCTCAGGCCATCCTGGACGAGCACCTTTCCAGAGTCCTCAAGACCCCTGGCTGTCAGTCTCCAGGATTGCTT[C/T]GACATTCCCCACGCTCTCGCTCTCCTGAACAGCGTCCCCTGCCTCGGGGAGGTCTCAGCACAAGGTCACAGTCTAGCTCTATGAATGGATATGTGCCAGCCAAGACCTTCATTTCTAGACAGTCAACCAAGCACATCCATCACCACTACATCCATCACCATGCTGGGCCTAAAAGCAAGGAGCAGATTGAGGTGGAGGCGACACAGCGGGTACAGTGCCTGTGCCATGGAACCTCAGAATGCTGCACTGCTCCTTACATTCGCAGCCGGAGTCTGGGCAGAGACCAGTGTGCCAGCCCTGCAGAAGTGGCCTTGGGGTAGGCTCGCCTATTTAATTTATCGTTTTAATTGTGGCATTTTGGTGTCTAGATAATAAAATTTTTGTTTTACTGATTTAATTTTTTTTTTTACTACTAGGCATTCCAGTACTTTATCCAAGCGTCTGTGTAAATCTGGAGAGGAGGTGAACATGGAAGGGCTGGAGAACAGTCTCCTCCAGCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40181
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000019803 | None | None | 268 | None | 3 |
| ENSDART00000020575 | Essential Splice Site | 561 | 812 | 7 | 11 |
| ENSDART00000124707 | None | None | 321 | None | 3 |
The following transcripts of ENSDARG00000014147 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 3 (position 56628176)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 55388047 |
| GRCz11 | 3 | 55639656 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTAGATAATAAAATTTTTGTTTTACTGATTTAATTTTTTTTTTTACTACT[A/T]GGCATTCCAGTACTTTATCCAAGCGTCTGTGTAAATCTGGAGAGGAGGTG
Long Flanking Sequence:
TTGTGAGGAGGATCCTCAGGCCATCCTGGACGAGCACCTTTCCAGAGTCCTCAAGACCCCTGGCTGTCAGTCTCCAGGATTGCTTCGACATTCCCCACGCTCTCGCTCTCCTGAACAGCGTCCCCTGCCTCGGGGAGGTCTCAGCACAAGGTCACAGTCTAGCTCTATGAATGGATATGTGCCAGCCAAGACCTTCATTTCTAGACAGTCAACCAAGCACATCCATCACCACTACATCCATCACCATGCTGGGCCTAAAAGCAAGGAGCAGATTGAGGTGGAGGCGACACAGCGGGTACAGTGCCTGTGCCATGGAACCTCAGAATGCTGCACTGCTCCTTACATTCGCAGCCGGAGTCTGGGCAGAGACCAGTGTGCCAGCCCTGCAGAAGTGGCCTTGGGGTAGGCTCGCCTATTTAATTTATCGTTTTAATTGTGGCATTTTGGTGTCTAGATAATAAAATTTTTGTTTTACTGATTTAATTTTTTTTTTTACTACT[A/T]GGCATTCCAGTACTTTATCCAAGCGTCTGTGTAAATCTGGAGAGGAGGTGAACATGGAAGGGCTGGAGAACAGTCTCCTCCAGCTGCCAGCTGACAGTACAGATCGCTCTCAAAATGTATGGCAATGGATCCTGGAGAGCGACCGACAAACCAAGCACAAGCCCCACAGGTTTGTAACTGCTGCTGTTGTAACTTTCATTCTCTGAGTTTGGTTTTAATTATGAAAAAAATTTATTTTACTTTTCTCCGAAATTGGCCAAATATTTTGAAGATGCCATTTGCTCCCTGCTGAAAAATCTAGCTTAAACCAGCCTAGGCTGGTTGGCTGGTTTTAGCTGGTCGACCAGGCTGGTTTTAGAGGGGTTTTGGCCACTTCCAGGCTGATTTCCAGCCATTTCCAGCCTGGTCTTAGCTGGTCAGGCTGGGAGATAACCAGCTAAAACCAGCTTGACCAGCCTAGCCAAGCTGGGAGTCCAGCCAAAACCAGCTATATCCAGCTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa45159
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000019803 | None | None | 268 | None | 3 |
| ENSDART00000020575 | Essential Splice Site | 771 | 812 | 10 | 11 |
| ENSDART00000124707 | None | None | 321 | None | 3 |
The following transcripts of ENSDARG00000014147 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 3 (position 56632509)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 55383714 |
| GRCz11 | 3 | 55635323 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTACCCTCGGACACTTCAAGGAACAACTACGGAAAAAAGGCAACTACAG[G/A]TATACTTTTAATTCTGACAACTTATTTATTAGTTCATTTATTTGTTCATT
Long Flanking Sequence:
GCTTTGAATCTACTTTAGCCTCAGAAGTCATGGACTGTTTTCTGTGCGCATAACCTACACGTATATTAGTTTTTATCATCGACACTAACATTTCAAATGACTACAGTTTTAAGTTTGATTGTTTAAATCCTAAATCCAATCGTAATAGCTGATGCTTGCCTTAGTAAACTTCACAGATACTATCAGAAGTTATCACGCGTCCATATAATCAAAACAAGTTTAACGTTAAATTGTAAAATGACAGAATTTAAACGTGAATGCCATCTTGCCAGCATTGGTTTTTACTTGGATTATCTTTATGTTTGCGCTCATCTATATTTGTGTTTTTACAGAAGGAAAGATCCTAAGAAGATGTCAGGCTGTCACAGTAGTTTGGGCTCGGAGACGGTAGTCACGTACTTCTTTTGTGGTGAGGAAATCCCATATCGGCGGATGATGAAAACACACAGCCTTACCCTCGGACACTTCAAGGAACAACTACGGAAAAAAGGCAACTACAG[G/A]TATACTTTTAATTCTGACAACTTATTTATTAGTTCATTTATTTGTTCATTTATTTATTTATTTAAAATGTATACAGTTCATCCAGAAAGTATTCATAGCACTTCACTTTTTCCACATTTTTTTATGTTAAAGCCTTATTTAAAAAAAAAATTAAATTAATTTATTTCCCCCAAAGTTTTATATACAATACCCCTTAATGTCAATGTGATTTTTTTTTATTGTTGTAAATTTATTACAAATAAAAAGCGTGAAAAATCACATGTACATCAGTATTCATAGCCTTTGCCGTGAAGCTCTAAATTGAGCTCAAGTACATTCTGTTTCCACTGATCATTCTTGAGATGTTTCAGCAGCTTAATAGGAGTTCACCTGTGGTAAATTCAATTGATTGGACATGATTTGAAAAGGCATACACCTCTCTATATAAGATCCCAGGGTTGACAGTGCATGTCAAAGCATAAACCGAGCATGAAGATAAAGGAATTGTCCCTAGACAATTC
Associated Phenotype:
Not determined