ZMP
aacs
Ensembl ID:
ZFIN ID:
Description:
Acetoacetyl-CoA synthetase [Source:UniProtKB/Swiss-Prot;Acc:A3QK15]
Human Orthologue:
AACS
Human Description:
acetoacetyl-CoA synthetase [Source:HGNC Symbol;Acc:21298]
Mouse Orthologue:
Aacs
Mouse Description:
acetoacetyl-CoA synthetase Gene [Source:MGI Symbol;Acc:MGI:1926144]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20372 | Nonsense | Available for shipment | Available now |
| sa40383 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa38456 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa33560 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa20372
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Founder:
SL6_01_H2
KASP Assay Location:
Unknown
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010101 | Nonsense | 31 | 673 | 1 | 18 |
| ENSDART00000099434 | Nonsense | 31 | 659 | 1 | 19 |
Genomic Location (Zv9):
Chromosome 5 (position 20681071)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 18393530 |
| GRCz11 | 5 | 18897322 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTCGAAGGTGCTCTGGTACCCGGACTCCAAGCGAAACACACAGACGGAC[C/T]GATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGGTGAGTAG
Long Flanking Sequence:
AACATCCTCAATATAATCTGACAGATGAATCAGACAGACCTTCCGCCAGGGTACGTGCAAGTCAGTAATTGCAAATGCTAGTTCATTAATCACAAATATATATAAAAATAATAGAAAATAAATTAAAAAAAGGAAAAAAATCTGAATCATCCATAGATTTTTGTGTAGAAACCGAAGCACTACATTAGTCGCGGAATAACACATGGAGGTTGTCAGGACGCAGTGCGGTTGCGCGGTAGGCGGGGCTTCCGCTGCTGCTGGTTGATTATGTTCGGCTGACGCTCGGAAGTGACCCATGTGTCTGACCTGCACCAATACACGATCACCGGATCGGCCCGTCCAACTCGCGTAGTGCGATTCTTTGAGTCTTCATAGCTTATTCACGATACGTTGGCGCGTGTCATCCGATCATGTCTAAAGACACGGAGGCCAAGAGCGAGGAGATTATGGAGTCGAAGGTGCTCTGGTACCCGGACTCCAAGCGAAACACACAGACGGAC[C/T]GATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGGTGAGTAGAGAGTCAGCCTGGGCTTGGTTGAATGTAGACTAACTACACACCCCTTATTCTCCAGGAAAACAAAGCATAGTACTATGGTTTGGTCTTAATCGCATTACTAGCTCATCCTAGGCTTGTCATGTTATGTCATGGTCACATTTAAGCAAAAACAGAGCTCTTTATTTTTTGCCCACTATATTTGATCCAGGATCCATTTTATATGTTTCATCTAGAAATAGATGCCTGACCACGTATTTCCAGTTATTCATGCATGCCAGTCTGCTAAATCTCAATGCTTGCATTAGACATAAGAAGTTGCAAAACCAGAATTTCAGATCAGACCTAGAATTTACACTGACAGCATGATTTATTTCCTTATGTCACTCTCATCTCTGTTCCTGTTATACAATTATATTTTGTCTCACAAATTTGTACATTTTTCCTAATAGTAAATGGTATATCCTTGTGTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40383
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Founder:
SL7_02_F10
KASP Assay Location:
Unknown
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010101 | Essential Splice Site | 45 | 673 | 1 | 18 |
| ENSDART00000099434 | Essential Splice Site | 45 | 659 | 1 | 19 |
Genomic Location (Zv9):
Chromosome 5 (position 20681027)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 18393486 |
| GRCz11 | 5 | 18897278 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGGACCGATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGG[T/C]GAGTAGAGAGTCAGCCTGGGCTTGGTTGAATGTAGACTAACTACACACCC
Long Flanking Sequence:
GCCAGGGTACGTGCAAGTCAGTAATTGCAAATGCTAGTTCATTAATCACAAATATATATAAAAATAATAGAAAATAAATTAAAAAAAGGAAAAAAATCTGAATCATCCATAGATTTTTGTGTAGAAACCGAAGCACTACATTAGTCGCGGAATAACACATGGAGGTTGTCAGGACGCAGTGCGGTTGCGCGGTAGGCGGGGCTTCCGCTGCTGCTGGTTGATTATGTTCGGCTGACGCTCGGAAGTGACCCATGTGTCTGACCTGCACCAATACACGATCACCGGATCGGCCCGTCCAACTCGCGTAGTGCGATTCTTTGAGTCTTCATAGCTTATTCACGATACGTTGGCGCGTGTCATCCGATCATGTCTAAAGACACGGAGGCCAAGAGCGAGGAGATTATGGAGTCGAAGGTGCTCTGGTACCCGGACTCCAAGCGAAACACACAGACGGACCGATTCCGAACTCTGGTTAACCGGGAATTCGGCTTGAACCTGGG[T/C]GAGTAGAGAGTCAGCCTGGGCTTGGTTGAATGTAGACTAACTACACACCCCTTATTCTCCAGGAAAACAAAGCATAGTACTATGGTTTGGTCTTAATCGCATTACTAGCTCATCCTAGGCTTGTCATGTTATGTCATGGTCACATTTAAGCAAAAACAGAGCTCTTTATTTTTTGCCCACTATATTTGATCCAGGATCCATTTTATATGTTTCATCTAGAAATAGATGCCTGACCACGTATTTCCAGTTATTCATGCATGCCAGTCTGCTAAATCTCAATGCTTGCATTAGACATAAGAAGTTGCAAAACCAGAATTTCAGATCAGACCTAGAATTTACACTGACAGCATGATTTATTTCCTTATGTCACTCTCATCTCTGTTCCTGTTATACAATTATATTTTGTCTCACAAATTTGTACATTTTTCCTAATAGTAAATGGTATATCCTTGTGTTGCTGATGTTTATGCTTTTAATAAATACAACAGTTAGTCTTATAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38456
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Founder:
SL7_01_F7
KASP Assay Location:
Unknown
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010101 | Nonsense | 420 | 673 | 12 | 18 |
| ENSDART00000099434 | Nonsense | 406 | 659 | 13 | 19 |
Genomic Location (Zv9):
Chromosome 5 (position 20627711)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 18340170 |
| GRCz11 | 5 | 18843962 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCCTCCACACACTCCTGTCTACAGGATCCCCACTGAAGCCCCAGAGCTA[T/A]GAATATGTGTACAGCTGTATTAAGAACAACGTGCTCCTGGGATCTATATC
Long Flanking Sequence:
GACTCTGATAACCAGGGCGAGAGACCCTCTCTACACGGGACCCCAGGCGGGTGGCCTGGCATGTCGCCTGCATACATTTTTCAGCACAGTTTAATGCGCTTACTAATTCTGATCACTGTGAACCAACCCATCTGCCTCCAGAATACAAACCAAGCTGAGCTTAGCTGTATTATTCAAGACTGAATTTACAACAAATCCAAACATGCTTGAATTTTTATTGAAGATTGATAGTGTCACTGCTGTTGATTACTGAATGAATATGTGGGCATCTCAAGCTGATTTGAATGTACAGTATGTGGCCATTATTGTTGTTGTTTTTTTATGTTGTACAAGCTTTTTTTTTTCATTAAATGCAGTGTTTTTTTTACATCGTGAGTCTTAAGCAGTTTTTTTTTAATTAATAGATTGTGTAATTCTTTTCTGTTTACAGCAAGCACACACAGCCTGCAGACCCTCCACACACTCCTGTCTACAGGATCCCCACTGAAGCCCCAGAGCTA[T/A]GAATATGTGTACAGCTGTATTAAGAACAACGTGCTCCTGGGATCTATATCAGGTGTGTTCTCCTTTATCTCTTTCCATTTCTTTTTCCTTCTTTCATTTGCTGCTTTACTTCTTTATTTCCGTTGTCTGCTTTTTATTTATTTATTTTTTTGTCCTTCCTGCATTTTATTACACAACTCGTTTTCTTTCCTCAGTTATTAACCAACATTCCTTCTTCTCTTCATATTTTTTTACTTTTATGCTTTACCTGCATCTTTTTCTTCCTACATTCCTTTTTAATATTTCCTCTTTCGTTGTTTCTTTCTACGGGTTTTTCTCTCTGTTTTTCAGTTACTCTCCTGACTCCATGCATTCCATTTGTTTGCTAATTTTCCTTTCTTTCCAGTTTCAGCATTTCCTGTCCTTTTCCCTCTTCTTTAGCTCTTCCTTCCTTCTGTCCCTCTTCAATGCCACCTTTCTTTCCTTATTTTTACCATATTTCTTTATTTTCCTTCTCCTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33560
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Founder:
SL6_07_G3
KASP Assay Location:
Unknown
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000010101 | Nonsense | 588 | 673 | 17 | 18 |
| ENSDART00000099434 | Nonsense | 574 | 659 | 18 | 19 |
Genomic Location (Zv9):
Chromosome 5 (position 20612153)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 18324612 |
| GRCz11 | 5 | 18828404 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGTGTCCCTCAGTACAACAGTGACGGAGAAGAGAGGGTGATTCTGTTTT[T/A]GAAAATGGGACCCAATAAGAGCTTTAGCCAGGAGCTAGTAGGAAAGATCC
Long Flanking Sequence:
GATGTCTCCTTTCTCTCTCACACCCCTTGCAGGTCCTTCAGTCTCTGCTAATGAGCTAATGATCTGAATCATCTGCTGTTTACATCAATATAGTGGATGTTTACATCAATATAGTGTACTTTTTCTGAAACCGTAAAACAATAATCAATATTTTTACGTTAACATGAAGGTTGCGTTTAGTTTTTCTGTAGGGTTAGATGCTATTAACATGGGTAATTTAATAATACAAATAATCCTCATTAACTTCAAGTCGAGCTGTATCCCTTCTAGCAGCAAATTGTGTTGTTTGACATCATTTTCAGTAAGTAGTTTGAACAAGGTGCAAGTGTAATTTCTTTGAGTGTATATGTGCTAACATTATACAGTAGCAAGACATTTTGTTAAGACCCCTGTTATGCTCTCTCTCTCTCTCTCGCCAGTTGAAGCCTTTGACGAAGTGTCCGACAGCCTTTGTGTCCCTCAGTACAACAGTGACGGAGAAGAGAGGGTGATTCTGTTTT[T/A]GAAAATGGGACCCAATAAGAGCTTTAGCCAGGAGCTAGTAGGAAAGATCCGTGGTGCTATTAGAGTAGCTCTCTCTGCACGACACGTACCAGCCTTGATACTGGAGACCAAAGACATCCCGGTGAGCACGGCTGCACATCTTTTTTTTTTTTTTTTGCTTGTCCTCTCTCTGCCTCCATTTTCTGCACTTTTCCACCTGACTGACTTTAAATTTGCTTTGCCCGCAGTACACTATCAGCGGAAAGAAGGTGGAAGTTGCAGTAAAGCAGGTGATTGCAGGTAAGGAAGTCACTCAGCGAGGGGCCTTCTCAAACCCAGACTCTTTGGACCTTTACAAGAACCTACCTGAACTCCAGAACTTCTGAGGTACTCATGCAGATTCCGTTCAAAGGAACGTCTATTGGACCATTTGGAGGGAATTAAACATTGAAGCTTTTTCTGCACATTGTGGCACTTACGCAAACTTCACTGGAGCCAATGGAGTTTGAACACGCAACACC
Associated Phenotype:
Not determined