Busch Lab

ZMP

usp25

Ensembl ID:
ENSDARG00000012314
ZFIN ID:
ZDB-GENE-040426-2847
Description:
ubiquitin carboxyl-terminal hydrolase 25 [Source:RefSeq peptide;Acc:NP_001001886]
Human Orthologue:
USP25
Human Description:
ubiquitin specific peptidase 25 [Source:HGNC Symbol;Acc:12624]
Mouse Orthologue:
Usp25
Mouse Description:
ubiquitin specific peptidase 25 Gene [Source:MGI Symbol;Acc:MGI:1353655]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa34963 Nonsense Mutation detected in F1 DNA Not yet available
sa16746 Nonsense Available for shipment Available now
sa21787 Nonsense Available for shipment Available now
sa41714 Nonsense Mutation detected in F1 DNA Not yet available
sa11988 Essential Splice Site Available for shipment Available now
sa18443 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa34963
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000115250 Nonsense 238 1073 7 24
Genomic Location (Zv9):
Chromosome 10 (position 39587071)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 38277042
GRCz11 10 38220800
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGGAGCTTAGGCATCTCTTCTCCTTGTTGGTGGGCTCCAAGCGGAAGTA[T/A]GTGGACCCGTCCGGGGCCGTGGAGATCCTCAAAGATGCCTTCAAGTCCAG
Long Flanking Sequence:
ATAATTATGCATCATTTAATGCAAGTTACCCACATTTTAACCCTAAGCATATTGTAAGTATATGTAATTAATTAATACATCACAGTAATTCAATGAATAGTTACACTTTACCAAGTAAACTTTAATTTATAGTGGGCTTTATTTTGTTTTCTGCTGTCACCAGGAAAATCTCTTATACTATATTTAAATGTGTGTCTTAAGCAAGTCCTACAAAATGTTTTTATTTATTTATTTAGTTATTTATTATTCAAATAAATAAATTTTAGCTTTTAGCTGACACAGACACTTTAACTTGGCCATTTATTACTTATATATTTATTACTTATAAACCTTGGTGTCCTACTGTTTAAGCTGTTTCTGGGAGGATATGTTGTTTTTCTGTGTGCTGTTAAGATTTTAATTTGCTCTCTGTATATGTTCCCATAGGAGCACAGGAACCTGCCCTTCATGCAGGAGCTTAGGCATCTCTTCTCCTTGTTGGTGGGCTCCAAGCGGAAGTA[T/A]GTGGACCCGTCCGGGGCCGTGGAGATCCTCAAAGATGCCTTCAAGTCCAGTGAGTCTCAGCAGGTAAGTTTCTTGAGTTGGTCACTAAAACAATATCTTAGGAAATCAAGATTTGCCTTGCCCTTATACTTTTATATAATACCATACGAATATACTACTAATTTTTTGAATGCATCGTTGGAAATGTTTTGTTTTTGTTAGCCTATTTAATCTCACCTGGGACCTCATGTACAAAGACTTGTGTTGAAATCAAACTAAAACATTGCGTACGCACAAAGCTGTAAATGTGTGTACGCAGTAAAGAATTCAGATGTATGAAACACTGCGTACGCGGAATCCCAAGCATTGTAACGAGTGGTTATTTGAGTTACTGTTGCCTTTCTATCAGCTGGAACCAGTCTGGCCATTCTCCTCTGACCTCTGGCATCAACTAGGCATTTTCGCTCACAGATATTCACTGGATATTTTCCCTTTTTCCAACCATTCTCTGTAAACCCTAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16746
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000115250 Nonsense 404 1073 12 24
Genomic Location (Zv9):
Chromosome 10 (position 39575539)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 38265510
GRCz11 10 38209268
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATACTTCCAGTTTTCAGAGAAGCCGCGTGTTGCWTGATTGATTTTNAGGTA[C/A]ATGGACAGGAACCGAGAGATCACACGGATAAAGCGAGAGGAGATCAGAAG
Long Flanking Sequence:
TGGCTACACAGGTGATCATGTGAGCTCTGCTACCAAATGAGGAGAAGAAGCAACGACGTCATTGCAACTTAATTTTTCTCCACCGCAAACACATTACTCAGAAAGAATTCAACTAAATAATAGCTGAGGACATGCTGCTGCTGTCTCTCACATTGTCCCACAACACCATTAAAATAGTGTAGAGGACAAGGTTTTATTATTTTATATTCACTTGACTAACAATTTTTTTTTAAGTAACCCAATAGTTACTTTCCCTAGTAAATAGTTACTTTTATAATTATGTAACTCCGTTACTCATTACCATAATTACTTTTTAAAAGGAATGTGCCCAACACTGGTCACAACAAACTTTGCCTGGCACATTGCATATGAAATTATGACAGCAAGGTTTTAATCAAATTGTTTTAAATGCTACCTTGAATGTTTAGAATTCTATACATGCAACTCAAAATACTTCCAGTTTTCAGAGAAGCCGCGTGTTGCATGATTGATTTTAGGTA[C/A]ATGGACAGGAACCGAGAGATCACACGGATAAAGCGAGAGGAGATCAGAAGACTAAAGGAGCACCTCACCGTCCTCCAGCAGCGACTCGAGAGGTTTGTTCACTCCATTTAACCTCCGCTCAGATCTAGCTATAACCTGCTGTTAACTGGCATAGCAAGAAAACCCCAGCTTTCAGCGTGAAAGAAGCTTTTAGGTTGCTGATGGAAAGATGGAAATGACACGCTGAGCTGTAATTTAGCTAAAGAATTATTAAGAATTGTTTCATATTTTTGCTGTCAATCTCTTTCCACATTTTTTTACTATACTCCACAGTTCTTTGTGTAAATTTTAATAGTAACTTCTGATAAACTTACTATAAACAATCAGTGAAGTGTTTTTAAAAATGTTGTACAGGGAGTTGTCATTATTATCTAATATTATAAGAAAGCTGAACAAAAATACTTTTTCAACTGACCATGAATTATCACCAAAACTTTCAATTTAGTTACTGATGTGTTGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21787
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000115250 Nonsense 705 1073 17 24
Genomic Location (Zv9):
Chromosome 10 (position 39562530)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 38252501
GRCz11 10 38196259
KASP Assay ID:
2260-3559.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTTTGTGGAGGCAGATAACAAGCTCTTCGAGAGGGAGATGGAGGAGTG[G/A]GATGCTTTACAGGCCCGCAAACTCCAGCAGGAAAAGTTGGCTCTGGCTGC
Long Flanking Sequence:
TTGCTTGGCAGCTTTTAAATATCTAGTTGTGTTATTTAACCAAATTGACAAATGGATAAACAAAAGCATTTGACCAATAAATTCATGCAATTTGATTATATTTTGTTCCATTTAAAAAGAGCAATTTAATCAGTAAATTAATGTACAGTTGTTACGACTGACATTTTAAATTAATTACAAATTTATTGTTTTTGATTTATTATTTGTGTCACCATTACCTACATTTTGAAAACCTTTAATTTGTGTTTACACTTGTAAGGTATGTGTTTTAATATGTATTATATGTATTATATGTAGATATTATATGTATAATATCTGTTTTAATATGAATAAAGTGTTCTATTTAATCTGTGTAATTCTGACTCTGTGCTTTGGTGTGTTTCAGAAGAGTTTGATAAAGAGACGGGACAGATGCTCAGTGGTTTGGACAAGCTTCCTCCTGACCTGAAGGTGTTTGTGGAGGCAGATAACAAGCTCTTCGAGAGGGAGATGGAGGAGTG[G/A]GATGCTTTACAGGCCCGCAAACTCCAGCAGGAAAAGTTGGCTCTGGCTGCTGCTGCTGCGGCTGCTGCCGCCGCTAGTGTGGCCGTCCAGCCCATGAGCACTGAACCCTGCTCTCCAGACAACACAGGTGAGCCAACGGTTCTTAAAGAGCCATGCTCAACTACATTATATGAGATTGTAACAGCAGTGTTTGTTTCTCACCTAATGAAGGTCTGTTAGCATCATTTTAATTGGAGAAAATGGTCAAATCTGGCTTTTTTGTACTATTTTTTGTATCCATCCATCTATCCATCCATCCATCCATCCATCCATCCTATTATTGCATCCATCCTCTCATATATTCTATTATTGCATCATCCATCCATCCATCTAATCTTTTATTGTATCCATCCATCTATCCATCCATCCATCCATCCTATTATTGCATTCATTCATTAATTCAATAATTCTATTATTTCATCCATCCATCCATCCATCGATCTATCTATTCTAATATTCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41714
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000115250 Nonsense 751 1073 18 24
Genomic Location (Zv9):
Chromosome 10 (position 39560730)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 38250701
GRCz11 10 38194459
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGCTACAAAAACTCAATGAAGCTAATTCTCAGCTCCATCAGCAGCTCCT[C/T]AGCATGACCCAGAGTACATGGAGCAACAGTCGCCCAGCGGAGACTCCAAA
Long Flanking Sequence:
CAATATTTCACTGAATTAAATTGAATCAAAATCGAAGTACTGAGGTTTTTGAAGAATTGACAAATATTGTATCGCTAGCTAAGAGAATCAATATTATATTGTATTGTGATGAGACATTCAATTTAACATTGTTAGTTATTTTTAACTATAGAGAGAACTGATCGATGTGGAAAACATTTTTGACCATTTAAAGAATCTTCATCTTCTTTTTTTTTTTTTAAATAAGCCTAATTTTTTAAAGGAGTGCACAATGTAACCACAGAAGAGTCCAGCTTTTTTTTTGTGTGTGAGATGCTTATGGTCTAGTCCGATTCTATGCTCTAATAGTAAAACTCAACTGTTTAACACTAGGGGAGTTGTAAAATGGGCCAATAAAAACAAAGTGGAGGGTTTCATTTAATAGTGGTTGAAAGACCCTGTAGTCACAATATGAAATTGAAACAACAATGACAGCTACAAAAACTCAATGAAGCTAATTCTCAGCTCCATCAGCAGCTCCT[C/T]AGCATGACCCAGAGTACATGGAGCAACAGTCGCCCAGCGGAGACTCCAAACACCTGCAGGAGGACACAGAGAGAGCCATCAGCAAGGCTGCAGCGGAGCATGATGAGAAGAGTCCAGAAGCTCTGCTTAATACAGTAAGACCTGCACAAACACATCATCATTCAGGTGTTTCTGCACACCTTCATTCACTCTTTAAATGCAGTGTTTAGAAAGACTGTAGGGTACGGCTGCACAAAATATTGTTTCAGCATGTGGACATCCAAATAATGTTTATTTGGGATTCTCCACTCTCCAGTGGAGACACTGGAAAGTTTAACCTTAAAGGTCACATGAAGTGCTTTGAGCAGAGTTGCACTCGCACCTTCAGGCTTGCACTCTCGAGTTTGCATGCTCAGGCGCCCACGCTTCCTATGCAATCAACATAAATAAACCGCAAGTAAGTTTCCAGTTCGTTTGCGCTGACAGCGACGACGTTGTCAAATAATTCTAATTCTAAGTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11988
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000115250 Essential Splice Site 908 1073 21 24
Genomic Location (Zv9):
Chromosome 10 (position 39544616)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 38234587
GRCz11 10 38178345
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGACGTCAGTGTTCCTGTTGATCGGCCTGGAATTATTYATGAAGAAAAG[G/A]TGAAGATCCATTTCTTGCATTTCAAGTTCACAGTTATGTATGCAAACAAT
Long Flanking Sequence:
AAATAAAAAAATAACATAAAAGTGACCATTTTATCATTGCATTAAAACATATTAATTATACATTTAATTTTGTTTTTTTAGTTCAGCTAAAAGAAAGAAATAAGACAAAAAATGTCAGGTGACATTTTAATTATTTTAGGAAATAAGAAATATTTCCTGTTTACCTAGCTATTACAATTATACATCTTTTTGTATTGCATTATAACTATATAGTTAATTTATGTTTATGTATTTTATGATTAGTTATTAACCTGATTTAGGTTTAAAATATTTAATTCATAAATTTACATTAAATAATTTACATTCAAAACTCCAGAACAATCAAATGTCAGAATTATACAAAATAATACAGACATTTTTAAAAAGTGATCTTGTTTCTTGTTTGGTTTACCTGCATTTTTTCTGCTTTTATAAACTCAGATGTGGCATCAGGACTACAGGATTTTCCGTGAGACGTCAGTGTTCCTGTTGATCGGCCTGGAATTATTCATGAAGAAAAG[G/A]TGAAGATCCATTTCTTGCATTTCAAGTTCACAGTTATGTATGCAAACAATCCAAACAGAGAGAAGTTGGTCTAGAATAGATTCTGGAACACTTTTCTAAAACATCACCACTAGATGGCAGCATATGCTAGTTTACCAACAGCTTACCAAAAATCCAAGAAACATTAAGCACAATAAATTCCTTAGCATTTAATATAATTGCAAATGTATCATTCAGCTGTTCATATTTAAATAACAAGTCAGTATTAAGATGCTATTCTCTCTCTTTTTTCTGCAGTTTTGTGGAAGCGTTGATGTATCTGATCTACGCCTATCAGTACAACAAAGAGCTTCTGGCGAAAGGGCCGTACAGAGGCCATGATGAGGAGCTGATCGCACATTACCGCAGAGAGTGCCTGCTGGTGACGGATTTCATTTTATTTATTTAATTATTTTTTATTAAGAGTGCAAATCATACAACATACTGTAAAACACAGAACACATAAACGGCAATGCGACTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18443
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000115250 Nonsense 954 1073 23 24
Genomic Location (Zv9):
Chromosome 10 (position 39539675)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 38229646
GRCz11 10 38173404
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AYTGATYTTTCTGTGTTGTTTTCGTGTGTGCTGTAGAAGTTAAATGARTA[C/A]GCTGCCGCTTTGTTCGAGACKGGCGAGGAGGCTAAAGTGAACACGGGTCW
Long Flanking Sequence:
GCAGCTTGGATCTGTTGCTGTTGTAAATCAGCCATACTAAACATTTGCTCTGACTTCGCATTGTACCCGCTGACCCCGTGCGGCCATTGTGCGGATAATATAATCATCAGTCCTGGAATAGGAAGCTAACTGCAGTCGGTGTGTAAACACATTAGCAGGAAGCGCGTCGCTGTCCTTGATTCACCTTTTTCGAGTACCGCAGAGGCCTTGACTTCATCTCAAGCTGTGCTGTTTACCCTCTGCTCGCTTTAATTGAAAAAACTGCTAACATTGACTTAGCTAATGTACTGCGATGGGGTTTTTTTATGCGCTTTCAGCCTAATTTCAGGAGAGCCTGGAAAAGGGTTAGAGAGTTTACCATGTCGCTTCTGAAGTTTAAGAGCGATTAATTGCGATGACAAAGAACATCAGCTTTTTGCGTCAGAGATGTTTTTGCAGTGGAGACTGTTTATTGATTTTTCTGTGTTGTTTTCGTGTGTGCTGTAGAAGTTAAATGAATA[C/A]GCTGCCGCTTTGTTCGAGACGGGCGAGGAGGCTAAAGTGAACACGGGTCTGAGCATCATGAACGATCTGGTGGTGCCCTGTCTTCCTCTGTTACTGGTGGATGAGATGGAGGAGAAGGACATGGTGGCTGTTGAAGACATGAGGAACCGATGGTGCTCATACCTGGGCCAGGAAATGGAGCGTAAGTTGGAGATCTTGTAAACTATACTTAGAGTATACAGAGGGGAAAATAAGAAGTAAACACGTCACTATCTTTCTCAAAAACATATTTCTAAAGGGGTTGTTGACTTGAAATTTTCCCCAGATTTGGGCAGCAACCAAAGAAATCCATATATGCAAAGAAAACAAAGCTGATTAGTTTACAAATGAAGTTATGTGTAATTAAATGAAATGACACAGGAAAAAAGTTTTGAACACATGAAGAAAGGGAGGTGTGGAAAGGCAGTGAAAGAGCCCAGACAGCAGCTGAAATCTCTCAGTAGTTCTTCAGTAACCCTCTG
Associated Phenotype:
Not determined