Busch Lab

ZMP

kif3b

Ensembl ID:
ENSDARG00000012081
ZFIN IDs:
ZDB-GENE-050119-3, ZDB-GENE-050119-3
Description:
kinesin-like protein KIF3B [Source:RefSeq peptide;Acc:NP_001093615]
Human Orthologue:
KIF3B
Human Description:
kinesin family member 3B [Source:HGNC Symbol;Acc:6320]
Mouse Orthologue:
Kif3b
Mouse Description:
kinesin family member 3B Gene [Source:MGI Symbol;Acc:MGI:107688]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa6722 Nonsense Confirmed mutation in F2 line Not yet available
sa39397 Nonsense Mutation detected in F1 DNA Not yet available
sa5805 Essential Splice Site F2 line generated Not yet available

Mutation Details

Allele Name:
sa6722
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102519 Nonsense 238 775 2 9
ENSDART00000122633 Nonsense 238 775 1 8
Genomic Location (Zv9):
Chromosome 23 (position 7789232)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 7781695
GRCz11 23 7715667
KASP Assay ID:
554-4517.1 (used for ordering genotyping assays)
KASP Sequence:
TCATCAMCATTGAGTGCAGTGAGTTGGGTCCTGAYGGAGAGAACCATATT[C/T]GAGTTGGRAAGCTTAACCTTGTTGACCTGGCAGGAAGTGAAAGACAGACC
Long Flanking Sequence:
TGGAGCTCTACGACGAGACTTTCCGCCCGTTAGTGGACTCTGTACTGTTTGGCTTCAATGGGACCATCTTTGCATATGGCCAGACTGGCACTGGAAAGACTTACACAATGGAAGGGGTACGAAACGACCCGGAAAGAAGGGGTGTGATCCCAAACTCATTTGAACACATTTTCACACACATCTCCCGCTCTCAGAACCAGCAGTACTTGGTCAGGGCTTCATATTTGGAGATTTATCAGGAGGAGATCAGAGACCTTTTGTCAAAGGACCAAGCACGTCGTTTGGAACTCAAAGAGCGACCAGACACAGGTGTCTATGTTAAAGACCTGTCTTCGTTTGTCACTAAAAGTGTTCGTGAGATTGAGCATGTGATGAATGTGGGGAACCAGAACCGCTCAGTTGGTGCAACAAACATGAATGAACACAGTTCTCGCTCTCATGCCATCTTCGTCATCACCATTGAGTGCAGTGAGTTGGGTCCTGACGGAGAGAACCATATT[C/T]GAGTTGGGAAGCTTAACCTTGTTGACCTGGCAGGAAGTGAAAGACAGACCAAAACCGGTGCTCAAGGTGAACGCTTAAAAGAAGCCACTAAAATCAATCTCTCCTTGTCAGCTTTGGGAAACGTCATCTCAGCGTTGGTGGATGGAAGAAGCACCCATATCCCGTACCGTGACTCTAAGCTTACAAGACTTCTTCAAGACTCCTTGGGTGGAAACGCCCGAACGGTTATGGTGGCCAACATTGGACCAGCTTCCTACAATGTAGAGGAGACTCTAACGACGCTACGCTATGCAAACCGCGCCAAAAACATCAAGAACAAACCCCGTGTCAATGAAGACCCCAAGGATGCCCTTCTTCGGGAGTTTCAGGAGGAGATTGCCCGCTTGAAAGAACAGTTGGAGAAAAGGTCTGGAAGGAAGAGGAGGAGAAGGAGGAGAAGAAGGGTTGGAGAAGGAGGAGAGGAGTTTGAGGATGGGGAGGATGAAGAGGATGATGATGAT
Associated Phenotype:
This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
trunk
ZFA:0001115
bent
PATO:0000617
abnormal
PATO:0000460

Mutation Details

Allele Name:
sa39397
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102519 Nonsense 427 775 2 9
ENSDART00000122633 Nonsense 427 775 1 8
Genomic Location (Zv9):
Chromosome 23 (position 7789799)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 7782262
GRCz11 23 7716234
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGAAGGAGTGGATGCAGATAAGAACATTGCAGATTATTGGCATGAGCAA[C/T]AGGAGAAGCTGGAGAAGGAGAGGAGAGCCATCATGGAGGACCACAGTCTG
Long Flanking Sequence:
GTGAACGCTTAAAAGAAGCCACTAAAATCAATCTCTCCTTGTCAGCTTTGGGAAACGTCATCTCAGCGTTGGTGGATGGAAGAAGCACCCATATCCCGTACCGTGACTCTAAGCTTACAAGACTTCTTCAAGACTCCTTGGGTGGAAACGCCCGAACGGTTATGGTGGCCAACATTGGACCAGCTTCCTACAATGTAGAGGAGACTCTAACGACGCTACGCTATGCAAACCGCGCCAAAAACATCAAGAACAAACCCCGTGTCAATGAAGACCCCAAGGATGCCCTTCTTCGGGAGTTTCAGGAGGAGATTGCCCGCTTGAAAGAACAGTTGGAGAAAAGGTCTGGAAGGAAGAGGAGGAGAAGGAGGAGAAGAAGGGTTGGAGAAGGAGGAGAGGAGTTTGAGGATGGGGAGGATGAAGAGGATGATGATGATGATGATGAAGACGAAGAGGAAGGAGTGGATGCAGATAAGAACATTGCAGATTATTGGCATGAGCAA[C/T]AGGAGAAGCTGGAGAAGGAGAGGAGAGCCATCATGGAGGACCACAGTCTGGTGGCAGAGGAGAAACAGCGGCTGCTGAAGGAGAAGGAGAGGAAGATGACTGACCTGCACAAAGAGAAAGAGGCATCAGAGATGCTGACAGCCAAAGTTAAGGTTAGAAACTTCAAGCTTTGAATGAAATACAAATACATAATGGAGTCTGTAAGGTGTTAAGAAAAATTTCTGGATTTACAATAGGGATGTCCCAATTAGATTTTTTTTTAATTTTGAGAATCTATCGATACCGAAACCCAATCTGATACTTCTATAATACATAAAAAGAATAAAGAAGAGCAAAGAAACAGATTCAGGATGTACATTCAACAACTCTGTTTACAAACAGAGCACTTCTGTGAGGTAGCTTAAACAATCAAGTGATAAATGATATAAATTCTTCACTTTTGGAATTTAGTGCAACAGTAAATATAAAACCAAACAGCACCTCAACTTAAGATACCCGGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5805
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102519 Essential Splice Site 631 775 7 9
ENSDART00000122633 Essential Splice Site 631 775 6 8
Genomic Location (Zv9):
Chromosome 23 (position 7798783)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 7791246
GRCz11 23 7725218
KASP Assay ID:
554-3518.1 (used for ordering genotyping assays)
KASP Sequence:
AGCATCCTTCCTGTTTTCATTTTAATGCTTCTTTCTCTGTATTATTTTCA[G/A]CAGTGATCATCAGATGATGAAAAGGCCTGTTTCYGCAGTGGGCTACAGAC
Long Flanking Sequence:
GACGGTGTGAACACGTGACAAGGGGGAGACAAGTGAACTTGGGTTTGGACCAGGAAATCAACCCAAGTGTGACAGCACTTCTAGGCTTTTTTGTTTTGTTTTCTAAGAATTTACCTCATTTCCTAACTAAAGTCTTAGTTTTAATACTCCAATTCGAACAATATATACTTAAATAGATTTTAATCATGGAATAGTGATCTAACTTTAAAGTAAATTGACATAAAAATGAAAAACAAACATTGCCACTACTGACATGAAAACATTTGCATTGTATCTACCAGACACTTAATCATAGAGAACTTCATCCCAATGGAGGAGAAGAACAAGATTGTAACAAGAGCCACATTTGATGAAGAAGACGATCTCTGGAAAATGACCCCCATCACCCGTATACAAAAGTATGTCGGCTTATTTTAGAAATGTAAAACTTATTTACAAACTGAGGCCATCAGCATCCTTCCTGTTTTCATTTTAATGCTTCTTTCTCTGTATTATTTTCA[G/A]CAGTGATCATCAGATGATGAAAAGGCCTGTTTCTGCAGTGGGCTACAGACGGCCTCTGAGTCAGCATGCCCGTATGGCCATGTTGATGCGGCCTGATGTCAGATACAAGGTATGCTGACACTGTTGCCATAATCCTCCACATGGCACAACACAAAGGCTTCAGTAACAATACACCCCCACTCTTCACAGCGACACAGATGAGCTTAGGAGAATCAAATGCATGACATGTCCTTGCTTATTCACTTTTGTTTATTTTAGTGAGGTTTTATTGATTTTCTGAAAGGTAATATGATATTGTTATATACAATAATGGAATAAGCCGAATGAAGTCAGGGTTTACAGAAAATTTATAACAGCTAATTGGTGTTTGTGCCTTAACACACTTGTTTTCACTGTATTGCATTAATACACTGTTTTGCATTTATTAAACACTTTTATAACTATAAATAGTTTATTTGGCCCAGTACCAGTATGGGAATGGTTGCTGATTAACTGTCACA
Associated Phenotype:
Not determined