Busch Lab

ZMP

si:dkey-71c4.3

Ensembl ID:
ENSDARG00000011855
ZFIN ID:
ZDB-GENE-081105-101
Description:
Novel protein similar to H.sapiens AAK1, AP2 associated kinase 1 (AAK1) [Source:UniProtKB/TrEMBL;Acc
Human Orthologue:
AAK1
Human Description:
AP2 associated kinase 1 [Source:HGNC Symbol;Acc:19679]
Mouse Orthologue:
Aak1
Mouse Description:
AP2 associated kinase 1 Gene [Source:MGI Symbol;Acc:MGI:1098687]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa13225 Nonsense Available for shipment Available now
sa21387 Nonsense Available for shipment Available now
sa34493 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa7158 Nonsense Mutation detected in F1 DNA Not yet available
sa31683 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa13225
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008058 Nonsense 41 569 1 13

The following transcripts of ENSDARG00000011855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 51226474)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 48977518
GRCz11 8 48966287
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGCGCGGGCTCCGGTGCMTTCATCGGACGCGTTTTCTCCATCGGACGCTA[T/A]CAGGTGACCGTGGAGGAGACCGTGGCCGAGGGTGAGTTGTTCATAGTCAC
Long Flanking Sequence:
GGAGGACGACCAGAGAAAGCGGCTTTTCTGGATTTTTTTCTTCTGACGGGAGCGCGCTGGCGTTCACCACATCTCCTATTATTATATATCATCATAATCCACAGAAGTATGAAGATCTGTCAATGGTGACTCATCCTACAGCTCTTATATGCGATTTCTTCTCCTCCTCCGAGTTGTTGTTTTGGATCTCCAGCACTTCATTTAGTCTGTTTTGAGAGTATATATTGATATATTAAGAGATTATCTTGCTTTTTTCTGTCATTTGTGCTGCTGTCACGCTTGATTGGGATCTGGGAGAACGGCGCGTGCACGAGTCCGGCTGATTTATCTGTATTATTTTCATGGTTTAATGACAATTAAAGTGTCGCCGGTTGGACAATGAAGAAGTTCTTCGATGCCCGACGGGAGATGGTGAGCTCCGGGCCCGCGTCTGGAGCCGGTGCGGGAGGCGGCGCGGGCTCCGGTGCCTTCATCGGACGCGTTTTCTCCATCGGACGCTA[T/A]CAGGTGACCGTGGAGGAGACCGTGGCCGAGGGTGAGTTGTTCATAGTCACAAACTGCTTGTTTTTAGGTCTAATGTGTGTATTAATAAATGATGATGCGATGTGAGTGACTCCAAACGTCTGGCGTCACTGCTCTCACTCATGCGTCATCTAAATATTTGCTGACCTCATGAAGTGAAGTGTGCTGTCTCAGCAGAGGAGGGGTACACTTTAATGTTGCACGCCACAGTTATCATTTTGGAGATCACTTACTATAGTGTTGTTAAAAAATGAAAACAAAACAAAAAAGTTTTTTAAAAGACTTTGTTTAGGTGTAAGAAAAAAGAAGAACTTTAGCAGAATGTTCAAGCTGCTCCCCCCATGTAATGGAAGCAATGTAAACTGGAGAAGTGTCAAGCAAAAAACATCTTAAAACTACAATTAAAGAAATCAGTAACTCCCTTAGTCTTCTGAAGCCACATGTTAGCTTTGTGGAAATGTTTCGTAATGTAAGTGATTAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21387
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008058 Nonsense 139 569 4 13

The following transcripts of ENSDARG00000011855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 51258301)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49009345
GRCz11 8 48998114
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTCTCTGCTAATGCAGGCGGGCAGGTTGTGAACCTGATGAACCAGCGTT[T/A]GCAGACGGGCTTCAGTGAGTCGGAAGTGCTGCAGATCTTCTGTGACACAT
Long Flanking Sequence:
AGCTCACATTGCTAGTTTTGTGGTGTACTGCATGTCATTGAGAACCAAAAAAAAAAGTTGTTTGCCTTTGTGATCTTTAATTGAAATCTGAAAATGTACTTTGTTTGTTTTTAGTCAAATTCTCTGAGGTATTGGGCGTGGCTAATATACTTAACCACGCCCCTCTAACTGTCAGTTTTGACGTTGAGCAGGAGGAGGAGGAGTCTGTTAGAATGTAATAACTCTCCCAAAACCCTTTTTCTGATCTTTCTGAATGAAATGCCTACTGTACTACATCCAATCAGCTCGCAGTAGAAAAACAAGCCCTGCCCACTGTTTTCTCATTTAATATTTCGTTTCTCTGAAAACTGCATCACAATACAAAAAAAAAAGTTTTTGCAGCTTCTGGTTTGTGGACTTTAGGAATTACATTTCAGATTAGATTTACTACTAATCTTCCACCATTTTTCTGTTCTCTGCTAATGCAGGCGGGCAGGTTGTGAACCTGATGAACCAGCGTT[T/A]GCAGACGGGCTTCAGTGAGTCGGAAGTGCTGCAGATCTTCTGTGACACATGTGAAGCTGTTGCTCGACTACATCAGTGCAAACCTCCCATCATCCACCGGGACCTCAAAGTATGTGCTTTCCAGACTATCAGTATGTAATTTCTTTCTCAAGAAGGAACTGTTATTGTGTTTTTCAAAATCTATTTGACTTTAATAAATTGCATCTAAAAATGTTAAATGATTTTGTGTTATTGCACCTTTTATTTATTTAATATTAAACATTGTATTTATATACAATGTTTTTTTCTTACATTTGTTTCATTCAATGTTATACATACATGCGAAGATGCATATATATATATATATATATACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACTGGCCACTTTATTAGGTACACTTCTCTAACTGCTTGTTAACGCCAATTTCTAATCAGCCAATCACATGGCAGCAACTCAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34493
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008058 Essential Splice Site 243 569 6 13

The following transcripts of ENSDARG00000011855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 51260256)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49011300
GRCz11 8 49000069
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGTCAATCTCTACGGAGGCATGGTCATCACTACTAAAGCAGATATATGG[G/T]TGAGTCAAGTCAAATAATCATTTACCTGCGGTGACAACAGGGTATTTTTA
Long Flanking Sequence:
TGTATTTACACAATAAGTACATTGTAAAAATCTATTAATTCCTTTGTAAGTACATATTAGTTAAGGCCACAATAAAGTGGGACCGAAAAAACATTATAGGAAATACTGTGAAAAGTTTCTTGCTCTGTTAAACAATTTCGGAATTATTCCAAAAACAAATTCACAGAAGGGCTATTTTAACTCATCTCGTTTCTTTGTATGTGTGTGTTGTAGGTGGAGAACATCTTGCTCCATGACAGAGGTCATTATGTGTTGTGTGATTTCGGTAGTGCCATCAACCGCTCCCAGAATCCGCAAACAGAAGGTGTGGCGGTTGTAGAAGAAGAAATCAAGAAGTAAGGGCTGATTTCTTTTGTTTGCGTTACACACTTCAGTTGTTCACATCAGTCAAATATATTTCCTCCTTGTGTGTTTTAAGGTACACTACTCTTTCATACCGCGCCCCAGAAATGGTCAATCTCTACGGAGGCATGGTCATCACTACTAAAGCAGATATATGG[G/T]TGAGTCAAGTCAAATAATCATTTACCTGCGGTGACAACAGGGTATTTTTAGTAGCAACCCAAGCTATTGTGTCTTGCCAATTATTGATGAATATGTAACCTGCTTTTATAGGATTAATAAAGATCACAAAGGATATTTTTAATTTTTTACAGTCTACAGTGCGCTCCATTAATAATGGCACCCTTGGTAAACATAACCATAGGAAAAATGGAGAGCCTTTGACCTTTATTAACTTTTGATCTTTTGCTCAAAACATGATCAAAAACATTTTAATTTTAAAAGTTTGGTTTTGAATGAGAATAGAGGCTTATTGTATTTTTTCAAAAAGATTTGGTTCATTTGAATTTATGGGGATTTGTTTTAAATGTCTTAAATAATACAGTCAAAGCTGCTTTATTGATGTTTTCATTCTTCATTTATTCATTCATTCATTCATACGTTCATTCATTCATTCATTCTTCATTTATTAATTTTGGTATTTTATTTGTTTTCTTTTAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7158
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008058 Nonsense 253 569 7 13

The following transcripts of ENSDARG00000011855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 51262294)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49013338
GRCz11 8 49002107
KASP Assay ID:
554-4630.1 (used for ordering genotyping assays)
KASP Sequence:
CTTGTATGTTTGTGTCYTCAGGCTTTAGGCTGCTTGTTGTATAAGTTGTG[T/A]TATTTCACRTTGCCGTTTGGAGAGAGTCAGGTGGCTATCTGTGACGGCAG
Long Flanking Sequence:
ATTTATTTATTCCTTCATTCATTTTTTATTTTCTTTATTCATTCATACATTTATTTGTTCATTTATTTATTTATTCATTTATTTTTTATTTTCTTTAATTATTCTTTTTTTCTTTCTTTCTTTATTTATTCATTTATTTTTTATTTTCTTTATTCGATCATTTATTTTTTGTCCATTTATTTTTTTATTTTCATTATTCATTAGTTTATTAATTTATTTATATATTTATTCATTCATTTATTTATTTATTTATTTATTTATTGTCATTATTCATTAATTAATTAATTTATTTATAAATTTATTTATTCATTTATTTATTTTAATAAAATCACAGAGGGCTAATAGTTTTTTGTCTTCATGCTACTGTATACTAAGAGTGCCATTGTTAACGAAAAGGTATTGTATGTGTTTAGTTGTTCTTTTTTTAGACAGTGCTCAGAAACAGTGTCTCTTGTATGTTTGTGTCCTCAGGCTTTAGGCTGCTTGTTGTATAAGTTGTG[T/A]TATTTCACATTGCCGTTTGGAGAGAGTCAGGTGGCTATCTGTGACGGCAGCTTCACCATCCCAGACAACTCCAGATACTCACACGATATGCACTGTCTCATCCGTAAGAACAGCTCTTCCTTTCTCTTCTGATTTATATGTTAAGGGAAGACTGTCTCACAGAGTTTGGTACTTGGTTTCATGGTTTAAATGTTGTGTGTCAATTAAGGCTTAATCCCTATTCCACCACTTAGCCCTTCCCCTTACTCCTACCCCTTGCTTTGCACTTTCATGTAAAAGGGAAGCATATGTTTTAATACATTCATAATGACAACAAATAATAACTTGACTTCTAATTGATCATTTGGAAAAGTGGCAGAAGGTAGATTTTTCCCATGAATCATCTGTTGAACTGCATCCCAATCATCACAAATACTGCAGAAGACCTATTGGAACCTGCATGGACCCAAGATTCTCACAGAAATCAATCAAGTTTGGTAAAGGAAAAATCATGGTTTGGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31683
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008058 Essential Splice Site 402 569 10 13

The following transcripts of ENSDARG00000011855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 51266939)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49017983
GRCz11 8 49006752
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTCCTCGCAAAAGACCCAGTGCACCTCCAGGACCCAGCCAACCAATCAG[T/C]GAGTGTTGTGTCTTTATGCTCAATCTCTCTCTCTCTCTTGCTCTCTCTCT
Long Flanking Sequence:
TTTTCAAATGAAGGCAGAGCTTCAAATGCCTGTGTGTCAGTATAGTGGCAGATTCAAAAACCAGACCAACGTCCTATGTTAATGAGGGAGAGCTCATCACTAACTGGTGGAGCTTTCCCCCTCTGATGATGCGTACAATGGGAGAATGTCGGTCTATGTGTTTTTATCAAGTGTGATTATAAGAAATAGAATTTATTAAATTTTACCATTAGTAGCTGGTTATCACAGACTGCCGCCACACAACTGTGTTTAAACCCCTTATGAAAGGGAAACAGGACCGCTTTAAACAGCCTCGTAATATGAAAGTTGTTGGTTTTGACTGAACTTTTCTTGTCATTCAGGCTCACTGATCCAGTCCCCACTACTGAGACATCCATCGCACCCCGGCAGCGTCCCAAGGCTGGTCAGGCTCAACCAATCACAGGCATCCTGCCAATCCAGCCAGCCCTCACTCCTCGCAAAAGACCCAGTGCACCTCCAGGACCCAGCCAACCAATCAG[T/C]GAGTGTTGTGTCTTTATGCTCAATCTCTCTCTCTCTCTTGCTCTCTCTCTCTCTCTCTCTTGCTCTCTCTCTCTCTCTCTCTCTCCCTCTCTCCCTCTCTCTCTCTCTCCCTCTCTCTCTCTCTCTCTCTCTCTCTCTATCTCTCTATCTCTCTCTCTCTTAACACCTCACACATCATAAAGACCCTTTTCACAAGACTGTTATGACACATTTAACAGTCATCAGCAGAACATCAACTTACACAACATCAGCCTAAATCCTTTTAAATATATGTTAATACATTTTAAGATGCTTTTAAAAGCTTTTAATACAGTAGCCCCTCTCTAAAACTTAGTTCACCTTTTCGCAGCCTTTTTTTAACGGTGCATTATGTTCTGCATCCTGATTGGTTGTAGACAATTGTCAACCACAGTGAGATCCTTTATTTACAAAGGGTAAAAGCATGAAACAGTAAAGAACCTTCCCAGGAGTGGCCGACTTACCATTTGCGGATTCCGCCT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3698
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008058 Nonsense 487 569 12 13

The following transcripts of ENSDARG00000011855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 51278788)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49029832
GRCz11 8 49018601
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGGGAGGACACAGAAGAATACTAAGTGATGTCACGCACAGCACCATATTT[G/T]GAGTTCCTGTGAGCAAATCCACCCARCTGCTTCAAGCTGCAGCTGCAGAA
Long Flanking Sequence:
TTATGACATTTTTGGTCGTGTCAGGTAACAAAGTTATGACAAACATGTCATAACAAAGACATCTTAAACATAGTCACCACTTAAATAATAAATGGTAATGACGCTTAATAACAATGGTAATAAGCTTTCATATATTCTTATTCATATTTAAGTGTCATGTCATTATTTTGAATGTTTTATGACAGTCTCATGAACATCCCTTTAAAGTATAAGGGGTTACCCACTTTTTCCCTCAACAAATCAGTGCAATTTTGTATTTCTCAATTCTGTAACTCTTTCTTCACTTTATGAAGATGACCCTTACCACTGAACAAATTTAATTTCCTCATGCATATCCTCGTCTTTAATGTTGTTCTGTATCTTCCTTTGTGTAAAAGTCTGCTGCTGGAAGTCGTGGAGTGCATAAAGTCGGCTCTTTGACTCCACCCTCTTCCCCTAAAGCCGCCCCTAAGGGAGGACACAGAAGAATACTAAGTGATGTCACGCACAGCACCATATTT[G/T]GAGTTCCTGTGAGCAAATCCACCCAACTGCTTCAAGCTGCAGCTGCAGAAGCCAGCCTCAACAAATCAAAGTAAATAATTAATTTGTATATTATTATAGAATGTTATATATAATTATTATTATTATTATATGATGTTATATATTATTACTTTATACATATATTTGTATATATCATTATTTTATGTGTTATTATTATTATATAATGTTATATATTATTTTTTATACAACAGTTCTGTCTGGTTCTTGAATCTGATTGGCTGTTAGCCAGTAACATCACACAAAGGCCTCTTCACCCTTCACCTCTGTGTAATAATCTTCCCACATACAGCAAGCAACAAGCAGAAAGGCTACAGTTTGACAAATATTACTGCTGTTACACAACAAAATGTACTTTTGAGGCTTTTATTAGTCAAGAATGTAGTTGTTTAGATTGCAACTATGCAGTTTATTTGTAAGAATAGTGCCTATTTTAAAATATTTAATATTTCTAAGAGCTCGTT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa5508
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008058 Nonsense 542 569 13 13

The following transcripts of ENSDARG00000011855 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 51281327)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49032371
GRCz11 8 49021140
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAAGTGTTTATCAGCCAGCGGATGCTTCTGGACACTYGGCTGGAGCTACA[G/T]GATCCTGGAACCCATTTGGCGAKGACAATTTCTCCAAGCTCACAGCAGAA
Long Flanking Sequence:
TCCACCATAGTGGTAGCTTTGCGCATTTCATCGCAGAAACCTCTGTAAATCTCAATTTAACACACCATTAGAAAACATTGTATGACTCCATGTGTTAATGTTGTGTAAAGACACACAATAACTGATTCCAAAATAGCTTTTCTTTTACATTCTGACACCAACTAGAAACTACAAATCTGCGAGGTCAGATTAACTCAATTAGTTTAAGTTCAGCCTAACACAATCAAATACAACAAACATTCATTTAAATCCAAGTGGAAGGAACTTGTTTCATTACTGCTTCATTTTACAGTGCAGAAACAAAGAAATGTTACAGCAAGGAAGATTGACATGAAAACTGAAACATGACAGCTATGGTGCATACAATCTTGGTGTGGAACTTTCAAGTTTGCGTTGTTTTCTGTAGGTCGGCTAGCACTACTCCATCGGGGTCTCCGTGTTCATCACAGCAAAGTGTTTATCAGCCAGCGGATGCTTCTGGACACTCGGCTGGAGCTACA[G/T]GATCCTGGAACCCATTTGGCGATGACAATTTCTCCAAGCTCACAGCAGAAGAGCTGCTGAACAAGGATTTTGCCAAACTGGATGGTAAAGCCAATGTTTTTAGATGAAATTAAAGCTGTGCATTGATTTCATAAGATAAATTGGTCTCTGATACAGTATCTGCGTAGTAGGTATGTGGTTTAGGCAAGTTCAAATATTCTCCTGAAGCTGTTTTATATGCTCATTTATAACCACAGGAGTTACCTTTAGAAGGAAAAGTTCGGCTTTGACCATATTTGGAATGGTTGTGAATATTAATGAGCTCTGCTTTGACACTCCGCAGCTATATCAATGTCTGCTTGAGTAGAATCCTTGTTAAACTTTTCAACTGAAGTAGTAGAGAGGTTTATTTTAGCTAGAAGGAATGAGTGAGCTTTTTTTAAGCCACCAGAGAAAACTAGTTAGCTTTTGAGCTCAGGCAGTATTCAATATCAACCTCTGCATAAACAAATGAGCTGCTG
Associated Phenotype:
Not determined