ZMP

wars2

Ensembl ID:

ENSDARG00000011801

ZFIN ID:

ZDB-GENE-050306-26

Description:

tryptophanyl-tRNA synthetase, mitochondrial [Source:RefSeq peptide;Acc:NP_001013341]

Human Orthologue:

WARS2

Human Description:

tryptophanyl tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:12730]

Mouse Orthologue:

Wars2

Mouse Description:

tryptophanyl tRNA synthetase 2 (mitochondrial) Gene [Source:MGI Symbol;Acc:MGI:1917810]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa41400	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa41399	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa41400

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000018570	Essential Splice Site	121	364	2	6

Genomic Location (Zv9):

Chromosome 9 (position 22118048)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21273834
GRCz11	9	21084703

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GGCCTGTGGAATCGACCCGACACGCTCCATACTTTTCCAGCAGTCTCAAG[T/C]GAGTCCTACATTAAAGTCCCCATGAACTGGAAGCTGCGACCTTTTTTTTT

Long Flanking Sequence:

TTCATTGGCTGTGGAGCAGTTCCGCTCTAGCACTCTCTCACCCAGTAGGGTGCTCTGTTAGTGCGAGACGTGCTTTGGATTTATCGCTTTGATAACATTCATAAAACTGTGTAGGGCGTCCCCTTTCTTCCTGTATGCTATCCACAAACCTTTTTTTGCCTTCATTTTTATGTGCAGCTTTGATTCTCGTATTACTGTTTGTCTTTCTTCTTAACAGATTTTGTCTCAAACTTCTCCACAGAGCCGCTCTAAAGGACTGGTTTTCTCAGGGATCCAGCCCACAGGTATTCCTCACTTAGGGAACTATCTCGGAGCGCTAGAAAGCTGGGTGGCCCTTCAGGATGATTACAGCACAGTCATGTACAGCATCGTAGACCTTCATTCCATCACTCAGCCTCAGGACCCTCAGGTGCTACGAGATAATATCATGGACATGGCTGCCAGCTTGTTGGCCTGTGGAATCGACCCGACACGCTCCATACTTTTCCAGCAGTCTCAAG[T/C]GAGTCCTACATTAAAGTCCCCATGAACTGGAAGCTGCGACCTTTTTTTTTTCCCTATTGTTACACAGTTCCTAGTGAAACTGAAATTTAAATGAGCAAACAGTGGGCTTTTCTTGTTTTTTCTGCTGTGGTCTGAATGGATGTAGTAAAGTAGGCATTTCATTCAGAAAGATCGGCAAAAAGGTTTGAGGAGAGTTTTTACAACTTAACAGACACCTCCTGCTCACCATTACTGTTTGTTGTCAAAACTGACAGTTGGAGGGGGTGGAGTTAAATATGTTAAACACGCCCATTTGCTAAGATAGACTTAATCTGACAAATTAACTGAAAAAAAAACACAGGAAGTGCATTTTCAGATTTCAATTAAACGTTAGAAGAGCAACTTTTTTCCCTTAATGACATGCACAGATGAATTGTTCACAAAACTAGCAATGTGAGCTAACAAAACCTTATGGTTAGTTTAGATTTTTTGGGGACTTTAAAGACTTTCAAGATTTCAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa41399

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000018570	Nonsense	204	364	5	6

Genomic Location (Zv9):

Chromosome 9 (position 22109561)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21265347
GRCz11	9	21076216

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAGCACTTGGAGCTCGCCCAGGACTTGGCCCGTATCTTTAACAACCAGTA[C/A]GGAGAGTTCTTCCCTGAGCCTCGTGCCCTGCTCAGTATGTTTGGACGTTC

Long Flanking Sequence:

GCTGTTTACTCAACAGCTGAGTGCATGTGAAACGTGGCGGAAAGCGGCCTTTGGATGCTGCCTGTGTGCGTTAATGTGGCAAAACTACTTCATTCAGGGACACTGAGACACCGCATGATGTTAGACCTCATTGTAATAAGAAAACAAACACACATTTGCAGCCAAATGTAATGAAAGGTGCTTTAGATTTATTTCAGACTTTCCCCTCTGCGCTTACCAGTGGTCAATCCTCAGTTTCTTTTCCTCGCAGATGAAAAGCAAGCAGAAGAATGAAGGCAGTGTGGGGCTTTATACATATCCGGTGTTACAGGCTGCAGATATTCTGCTCTACAAGTATGACTCGGCTGGGCTCTTAATATGTGTTGTTCTATTTCCAGTTTTTGTTTGAGAGAGAGACTGATGTTATTGTTGTGCAGATCCACACATGTGCCAGTAGGGGAGGACCAGATCCAGCACTTGGAGCTCGCCCAGGACTTGGCCCGTATCTTTAACAACCAGTA[C/A]GGAGAGTTCTTCCCTGAGCCTCGTGCCCTGCTCAGTATGTTTGGACGTTCTCGTTTTTTACCTCATGACTTTACATACATTATAATAATGAACATGCACAATACTGACATAGTGGGCACTCAAAAAAAACATGATTATTTATTGTTAAAACTATTAGAGTGCATTTTAGGAATATTCACACTGTATCCGCAGTAGTGTCTAACCACGCCAAATGCTTGGAGACTTTTATAGGTTAAAAGTTTAAACATTAACATTTTTAATTTACTTGATCTACTACATGACTAAAAGTTCTGCGACTATTTGGCTTTATATATTCTTTTTAGATGATGTTAGTTTCTTAGTTGATGCTTCACTCAAAAAATATTTTTGCAGCTTGTTCAAACTACTTATTTAAAAGGAGCTGAAACAACACAATTCTGGAGTGTTTTTGGGAAACGGAATTATTTAATTGTTGTTATATTAACTTAATTGATTTGTGTTTGGACAACAAGAATGATTTG

Associated Phenotype:

Not determined