ZMP

chuk

Ensembl ID:

ENSDARG00000011662

ZFIN ID:

ZDB-GENE-040426-1069

Description:

Inhibitor of nuclear factor kappa-B kinase subunit alpha [Source:UniProtKB/Swiss-Prot;Acc:Q4G3H4]

Human Orthologue:

CHUK

Human Description:

conserved helix-loop-helix ubiquitous kinase [Source:HGNC Symbol;Acc:1974]

Mouse Orthologue:

Chuk

Mouse Description:

conserved helix-loop-helix ubiquitous kinase Gene [Source:MGI Symbol;Acc:MGI:99484]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa35487	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa35488	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa35487

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000027428	Essential Splice Site	159	758	6	22

Genomic Location (Zv9):

Chromosome 13 (position 25590725)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	25236385
GRCz11	13	25366835

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAGGGATCTCAAGCCAGAGAATATTGTGCTGCAAGAAATTAATGGAAAGG[T/C]ATTTACTTTTTAGTGGTTAGAATTTTATTCTATAGACATGCTTTTCAAAC

Long Flanking Sequence:

CTAATCTTTTTTTATCCTACTTCTAAGGCTAAAGCACCTTAATGTTGTCACAGCAAAGGATGTGCCTGAGGAGATGATGCACATTGCCTTGAATGATTTACCACTTTTAGCCATGGAGTATTGTTCCAAAGGAGATCTTCGTAAGGTGTGTGCGTGTGACCATAGGCTTTTCTTTTGTATCTGTCAGATGTGCTCTTATATTAAGTTCATTCTGACTCATTTCTGTTTTTTAATTCTTTTTTTGTAGTTGTTGAGCAAACCTGAAAATTGCTGTGGGTTGAAAGAGAGTGAGGTGTTGTCTCTACTCAATGATGTTGGTAATGTGTCAAAGCCTGTTGCTTCTGTTTTTAGTATTTTTACCATCAATAGCTGAGGGTTGTGTGTCAAACTGAGTGTTTTCTTTTGAATAGGTTCTGGAATCCAGTACCTTCATGAGAATAAGATCATACACAGGGATCTCAAGCCAGAGAATATTGTGCTGCAAGAAATTAATGGAAAGG[T/C]ATTTACTTTTTAGTGGTTAGAATTTTATTCTATAGACATGCTTTTCAAACATGGGTTATGTTTTGTTGTCTATGCAGCTTGTTCACAAGATAATCGACCTTGGTTATGCCAAAGACCTGGACCAGGGGAGCTTATGCACTTCATTTGTGGGGACTTTACAATATCTGGTATGTTTTAACCTGCATTATTTAGAAATATGACAGTTATGGCAATAATCTCACATACACTTTCATATGCTGGAGATTTTTTATTAAGATGCAGGGAATTTTTTGTGTCTAATACCTGTCAGTTTTGAGATTTTGGAGATTGTTCTTTGTACTCATGGGAAAAAAAACATCCACAATGCAATTTTAAGTGTTTATTTTATACTAATTTATAATTATAGAAAAAAATACCATTGTTATTTTAATAACATATTTTTTAAGGCTGTTACCTCAAAATGAGTTTTTCACTTGTAGTGATCCCTGTTTTTACTCCAGTATCACTTACACCAAATTTCC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa35488

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000027428	Essential Splice Site	504	758	14	22

Genomic Location (Zv9):

Chromosome 13 (position 25596143)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	13	25241803
GRCz11	13	25372253

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ATACAGTACGACTTGGAGAAATACAGTGATCAGATGCAGTATGGCATATG[T/A]ACGTTTTTGAATATGCTGCTTTGTTGATAAAGCTAAAAATGTGTTATTGC

Long Flanking Sequence:

GAAAGTGTCAACTTTATTGGTAAGATATGATTTGGCTTTTCTTTGGATCATTTGTTTAGATGTTATTGCGTGAAATGTGAAGTATTTGTAAACTTTCATTAGAATATTAAAATTCCTTAACTCGTTTTGTGTTTCAGTTCGGGAAACCAAAACTCAGCTCCCACTAAGTACCCTAAAAAAGGTTTGGGGTGAGGCGGTTAGCTACATTTGTGGCCTCAGAGAAGACTACAGCCGCCTCTTCCAGGGCCAGCGTGCAGCCATGTACATACCTTACATTTACTATGCTCGTTAATGTCTCTGTCTTGTGTTTTGTTCTGTTCATAATTGAATCATTTGTTTGTTTGCAGGCTGAGTCTTCTTCGCTTCAATACAAATTTGACAAGATACAAGAACATGATGTTCTCCTTTTCACAACAGCTCAAAGCAAAGCTGGACTTTTTTAAGACCAGCATACAGTACGACTTGGAGAAATACAGTGATCAGATGCAGTATGGCATATG[T/A]ACGTTTTTGAATATGCTGCTTTGTTGATAAAGCTAAAAATGTGTTATTGCATTATTGATTAGTAATAATCCATTTTTTTTGTAGCTTCAGAAAAGATGCTGAAGGCTTGGCACGAAAATGAAGAGAGGGCTGCTGCTTTTGCACAGGTGCTGTGAATGAATGATACACAAAGTAGTTTTAAAACCTTTAATAAATAGTCATCTAAGTGGATTTCACATTTTTGTAAAAAAAAAAATCTTTTTGACCAGCATATCTGTTGTGCAAATGTATTTGTATGTGGGTTTACATTTGTTTTAACTACAACTAAAACAACTTTTTTATCTTCTGAAGGTGGCAGAGATTGGTCATCTGGATGAGGAAATAATGGCGTTGCATTCGGAAATCGTTGAGTTACAGAGAAGTCCTTATGCTCGTCGTCAAGGAGATGTCATGGAGCAGTTGTGAGAACCTTTGTTCAGAAATAAGCTTTGTGAAGTTTATCAGCATTTATTTTGACATAA

Associated Phenotype:

Not determined