Busch Lab

ZMP

abcb11a

Ensembl ID:
ENSDARG00000011573
ZFIN ID:
ZDB-GENE-050517-13
Description:
Novel protein similar to vertebrate ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ABCB11)
Human Orthologue:
ABCB11
Human Description:
ATP-binding cassette, sub-family B (MDR/TAP), member 11 [Source:HGNC Symbol;Acc:42]
Mouse Orthologue:
Abcb11
Mouse Description:
ATP-binding cassette, sub-family B (MDR/TAP), member 11 Gene [Source:MGI Symbol;Acc:MGI:1351619]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa44714 Nonsense Mutation detected in F1 DNA Not yet available
sa34768 Essential Splice Site Available for shipment Available now
sa18968 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa18599 Essential Splice Site Available for shipment Available now
sa45380 Nonsense Mutation detected in F1 DNA Not yet available
sa21601 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa44714
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047401 Nonsense 5 1281 1 25
ENSDART00000134566 None None 609 None 12
ENSDART00000139631 None None 635 None 12
Genomic Location (Zv9):
Chromosome 9 (position 49806243)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 49061439
GRCz11 9 48758924
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGAATGGTGAAGTCAAAAAAAAAGAGAAAGCACCGACTGTCGGATTCTTT[C/T]AGCTGGTAAGCATCTCAGTAGTACTCTACGACGTTTTTTCGTTACCTGGA
Long Flanking Sequence:
CTCGACTAAAAAAAGCCTCAAAAGTACATTATGTTGTCCAACAGCTGCATTATTTGTCAAACTGTAGTGAGTCTATTGATCTGCTGCCACTCTCTGCAGGTGGAGTGAAACAAAAGGGTGAAGAGGATGTATGAGTGCTGTTATTGCAGAATATATCTCGGCTATCAACCAATCAGATTCTAAAACCAGACAGAACTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACAGTAAATACAAGCTTTAAATTTGAATTTGATTAATTGTGATTAATCATTTGACAGCACTAATATAACAGTAAATTTGTAAAAATCTATTTTAGCTTGACCAAAATATCAATAATAATCTGATTTAGGTTTCACTACAGCTACAGTTTCTAAAATATTTCTGTGTTTGAAGGAATGGTGAAGTCAAAAAAAAAGAGAAAGCACCGACTGTCGGATTCTTT[C/T]AGCTGGTAAGCATCTCAGTAGTACTCTACGACGTTTTTTCGTTACCTGGATCAAAATATTAAATTATTAACTGAATGTTTTTAACAACTGAAGTTGGGCAGCAAAAAGGTCACTGGTTTGAGTTCTGGCTAGGCCAATTGGCGTTTCTGAGTGGAGTTTGCATGTTCTCCCTGTGTTGGTGTGGGTTTCTCCGGATGCTCCGGTTTCCCTCACAGTCCAAAGACATGCAGTATAGGTGAATTGGATAAACTAAATTGGCCCTAGTGTATGTGTGTGAATGCAAGACTGTATGGGTGTTTCCCTGTGATGGATATCCGCTGCGTAAGACATATGCTTTATTGCCAGGTATGTTCATACATTCGAGGAATTTGTTTTGGTGACAGAGCTTCTACAGTGCAACAGAATGACAAAGACAGGATATAAAACAGATAATAAATATATTTAATAAAAATAGAAGTAGTGAATGCCAAGGCTGGAGTGGGACTCCTTCAGCCCTGGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34768
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047401 Essential Splice Site 160 1281 4 25
ENSDART00000134566 Essential Splice Site 154 609 3 12
ENSDART00000139631 None None 635 None 12
Genomic Location (Zv9):
Chromosome 9 (position 49811110)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 49066306
GRCz11 9 48763791
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGGTTTGACTGCAACTCTGTGGGGGAGCTGAACACGAGGATGTCTGAG[T/C]AATGTCCAAGTCTATCTGTGTTATCTTAAACCATTGTTAGCTTTGCTCAC
Long Flanking Sequence:
AGTGCACTAATTATTTTTAGAGTTTTTAGTGTGAACACACTACTTGCACTATTTATACTACAAAATGGCGTAGAATAGTGCATAAGTATGTGATTTGGGACGCAGCTTCAGTCCTGGAGAGCCAGTGTCGGAATTTAACGCCAACCCCAATCAGACACACCTGGACTAGCTAATCAAGCTCTTACTAGGCTTTCTAATAACATCTGTGCAGTTGTGTTGAGGCAAGTTGGAGCTAAAATCTGCAGGACACCAGCCCTCCAGGACCAAGTTTGAGCACCCCTGATTTAAGTAGTGCATATTTATAATAGCAAAACCTCATCTGGTTTGCACATTGTCAGTCTAAATGAGCTTTTCTGCGGTTTCAGATCACGTTTTGGGTTTCTGCAGCTGCCAGGCAGATCCAGCGCATCCGAAAAACCTACTTCAGAAAGATCATGTGCATGGAGATCGGCTGGTTTGACTGCAACTCTGTGGGGGAGCTGAACACGAGGATGTCTGAG[T/C]AATGTCCAAGTCTATCTGTGTTATCTTAAACCATTGTTAGCTTTGCTCACAAGCCTGTGATTAGTGGTGTTAAATATTAAACTCGGGTTCTAAAAACAGGTGTCTTCAATAGCTATTCGATCTGTATTTGGTGGAAGATGGGGATAAAAGTTTCTTATTGTGGAGTTAGACTATTAGTGTGTTTCATAAAATTTTGTTTTATTTCTAAAGATCTGGGCCTGGTTGTGCTTTATGAAAGCTTAAGCTAACAAACCCCTTTATTATAAAGTTGGAAGTTGGGTGACATGATGGCTCAATGGTTAGCATTGTCACCTCACAGCAAGAAGGTCATTGGTTCGAGCCTCTGCTAGGTCAGTTTGCATTTCTGTGTGGAGTTTGTATGTTCTCCCCGTGCTGGCGTGGGTTTCCTCTGGGTGCTCCAGTTTGCCTGACAGTTTGCCTAAGACATCTGCTAAGGTGAATTGAATCAGCTAAATTGTCTGTAGTGTATGTATGTGAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18968
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047401 Essential Splice Site 160 1281 5 25
ENSDART00000134566 Essential Splice Site 154 609 4 12
ENSDART00000139631 None None 635 None 12
Genomic Location (Zv9):
Chromosome 9 (position 49816762)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 49071958
GRCz11 9 48769443
KASP Assay ID:
2260-2534.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCTTGCATAGATACTAGTTTAATTTAGCATGTTTGTTACTTTTTTGCA[G/A]TGACATCAACAAAATCAACAACGCTATAGCGGACCAGGTGTCCATCTTCA
Long Flanking Sequence:
GTAACAGACACACTGTACCTCTTCCCAACAGGGAAAAACATAAACAATCATGAATGCATGATTATATGGTGTCATAGCTTTGCAAACAAAAAAATGTCATTTTAATGGAAGTCAATGGGGCAAAAACAGACACCAACATAACGAAAGGATAGTAAATTTGCCCAGAGTGTATTGTTGTTTTTTTTATTTTATTTTTTTTTTATTAAGATTTTAGAGCATTTTCTTAAAATGTGTGTCAAAATAAAATTTGTCACCAAAAATCACCCTATTTGCTGAAACAGATATTTGTGGCCAAATTAAGACTCAAACTCCCCTCAGAGTGGATGAAAACATCCCCAAGAGCACACGAGGGTTAACTTTGCTGGAGCTGTAGAAAAAAACAACAATGTTGTGCATGAAATGAAAAATTAATCTCACAGTGAATGCATCTTTAAGTATTTCTGCTCATTTCATCTTGCATAGATACTAGTTTAATTTAGCATGTTTGTTACTTTTTTGCA[G/A]TGACATCAACAAAATCAACAACGCTATAGCGGACCAGGTGTCCATCTTCATTGAGAGGATCTCCACGTTTATATTCGGCTTCATGGTGGGCTTCATCGGCGGCTGGAAGCTGACACTGGTGGTCATCGCAGTCAGTCCTCTATTAGGCCTCGCCGCAGGACTCATGGCTATGGTCAGTTTCACCACAGACAAATCAATATGAAGGAGACTGGAGTCAGGGATTGTGTGGGGTTTACAAACACTTAATTCAACATATTACAGATAAAGGCCTTAAAGGGAGAGTTCACCCAAAAATGAACATTTACTCACTATTTATTCACCCTCTTTTTTTCTTCTTCTGTTGAACACAAAAGAAGATAGAGTATTTTGGAGAAAGCTGAAAACATGTAACCATTCACTTCCATAGTAGGAAAAACAAATACTATGGATGTCAATGGTTACAGGTTTACTGCTTTCTTCGAAATATCTTCTTATGTCTTCAACAAAAGAAAGAAACTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18599
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047401 Essential Splice Site 317 1281 7 25
ENSDART00000134566 Essential Splice Site 311 609 6 12
ENSDART00000139631 None None 635 None 12
Genomic Location (Zv9):
Chromosome 9 (position 49824965)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 49080161
GRCz11 9 48777646
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TAAACTGGTCATCGAGACCCAGGAGCKCACACCTGGAGGACTCGTTCAGG[T/G]AGAAATGACTCTCAGAATTTAATTTTTCTGTTCAAAACAAYATCTTCACA
Long Flanking Sequence:
CTATTCCTTAGTTGTGTATTTATTTAAGCAGGGATATATATATATATATATATATAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAAATTATGTGTAAAGTGCTAATTTTGATCAAGTCATCATTTTTTTTTGTCTTAGTTCATTAATTTGAGCCTAAGAATTGCATAATTTTGATTTGGTATACATTAAAATGATGACATCAGTCAAATTTGGGAGATAAAAAGTCAAACTTTTGACATATGATGCTAAATTGCTGGCTGGCAAAAGCTGTACAGGCAGAAACTGTTGTGTGGTTTATGCCCGCAGGTATGACAGGAATCTGGTGCAGGCGCAGGAGTGGGGCATAAAGAAGGGCATGATCATCGGGGTGTTTCAGGGCTATCTCTGGTGCATCATATTCCTGTGTTACGCTCTCGCCTTCTGGTTCGGCTCTAAACTGGTCATCGAGACCCAGGAGCTCACACCTGGAGGACTCGTTCAGG[T/G]AGAAATGACTCTCAGAATTTAATTTTTCTGTTCAAAACAACATCTTCACACATTTAAACTCCGGTCTGTTCCTTAAGGGTATTATTTGTAATTAAAACTATTAAATATGTTTGTTACCTTACTCTTTCCCTGCCGGCGTTTAGAAAAAAAATAGTTGCCAGCCACCAACATTTTTAATATTTTTTTCCTACATTTTTAAATATTTTCTGCTTGGAATATATGAGCATATTATATATCAAAATAAAGAACCAAGACTCTGCTTTCAAACAAAAAAGCATTTTATTTTTCATGTGTTCATGTTGTAATCCTATTTAAATGCATGTATGCAGGGTGTCAATAAACAAGCAACAAAAACTAAATCATATATTAATATTTCGGATGAAGTAGTTCGATTTTTAAGCACAAGTGAAAATATAATTTATTGTGGACTTTGAATTAAACTAACAAACATCATATACACAAGTAAATCCTCTGAGTAAAGTTTACTCAGTTTAGATAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45380
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047401 Nonsense 422 1281 10 25
ENSDART00000134566 Nonsense 416 609 9 12
ENSDART00000139631 None None 635 None 12
Genomic Location (Zv9):
Chromosome 9 (position 49832217)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 49087413
GRCz11 9 48784898
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGACGACAGCGTTTGTTGGACCCAGCGGATCAGGAAAAACCACAACAATA[C/T]AACTCATCCAAAGGTTCTACGACCCAAGTGAAGGAATGGTACTGTCATTT
Long Flanking Sequence:
TATATTTCGCCTTAAATTAATATTGTTCGCTGTTCTCTGTCATCCTGAGGCCACCGGCCGGCGTTGAGCCCGGGTGCGAGGTTCCGTTTATCGCTGCTTGCAGCTTTAATTTGTTTTGTATTTTTCATAGGTTTTATATGTTTTAAAAGTAACCTCAAAGAAATGTAATTAGTAATCTGATAACTTTTTACATGAAGTCATTAGTAATGTGATAAGATTACAATTTTGCAGTTGTCAGTAATTTGGAATCAGTGTTGTTTTTTTTAAAGTAACTTACCCAACACTGCTTCGTAATGTGTTCAACAGAAGAAAGAAACTCAAAAGAGTGAGAAAGGAGTGAATAAATGTTCATTTTTGTGTAAATTATCCCTTTAGATTATGTCTAGTATTACCTGAGTATTTCTTGTGTTCAGATATTAGATGATTTGAACATTGTGGTCAAAGCTGGCGAGACGACAGCGTTTGTTGGACCCAGCGGATCAGGAAAAACCACAACAATA[C/T]AACTCATCCAAAGGTTCTACGACCCAAGTGAAGGAATGGTACTGTCATTTGATCCAGTAATATTTTGATATTATTAATATGCCTTCTGGGTGGCACTGTGGCTTAGTCTTTACCACCTCACCTCATAGCAAGAAGGTCACTGCTTTGAGTCCTGGCTGGGCCAGTTGGCATTTCTGTGTAGAGTTTGCATCTTCTCCCCCTTGTTGGCGTGGGTTTCCTCCGGGTGCTCCGGTTTCCTCCATAGTCCGAACACATGCGCTGTAGGTGAATTGGGTAAACTAAATTGACCGTAGTCTATGAGTGTGTATTGGTGTTTCCCAGTACTGGGTTGCAGCTGGAAGTGTATCCGCTGCATAGCCGTATGTCGGAATAGTTGGCGGTTCATTCCGCTGTGGCGACCCTTAATAAATGAAAGGACTAAGCTGAGAAAAATTAATAAATGAAATGATTTATGTTTGAGCAGTGTGTATGTAATTATGCACATTGTATTTATTAGCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21601
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047401 Essential Splice Site 559 1281 12 25
ENSDART00000134566 Essential Splice Site 553 609 11 12
ENSDART00000139631 None None 635 None 12
Genomic Location (Zv9):
Chromosome 9 (position 49833688)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 49088884
GRCz11 9 48786369
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGCGCTGGATAATGAGAGTGAGGCTGTCGTACAGGAGGCCTTGGACAAG[G/A]TGAGACTAATGATATCCTCACCAGCTGATGCTAAAATATAACTTTGGCAC
Long Flanking Sequence:
TAGAAAATTCCTGGCAGGTGTGTTGAAGCAAGTTGGAGCTAAACTATGCAGGACACCGGCCCTCCAGGACTGAGTTTGAACACCCCTGTATAACCGTATCTCAGTCAATGTTGGGTGTAATGCGTAACAAAATACACTCAAATTATTTTTGCTGCTCTTTCAAACTACTTATTTAAAATTAGATAAATCGACACAATGTTTCAGATTTTTTTCAGCTTAATTGTTTCATGTTCAACGTTTTTAATAAAAAATACCTTTTTTATGTTAGCTCTGCAATTTTTGCATATTAATTCTGGAGATCAAACTAATTAAAGCGTGGTGCTTTGCAGACATTTGACACATTGGTTGGTGAAGGTGGAGGGCAAATGAGCGGAGGACAGAAACAGAGGATCGCCATTGCTCGAGCGCTGGTCAGGAATCCCAGAATCCTCCTGTTAGACATGGCCACATCAGCGCTGGATAATGAGAGTGAGGCTGTCGTACAGGAGGCCTTGGACAAG[G/A]TGAGACTAATGATATCCTCACCAGCTGATGCTAAAATATAACTTTGGCACAGTCATTCTTTTATCCTGCTGACTATATTATATGCATTCTAATTAATCCAATTATTGGTTTTCCATAAGTGACAAATGGGATCTCAATAAGCACTTGTTTATTAGTCAGTGCACTGATCAGGGCGTGAGCCATTTTAAGTGTTGTCTCAATTACACAAATTTTCCAGTGCACTGAAACGCCTGCACCCTGAAAAGTCCCACAATGCACAGTGAATTCATCGAAATGCAGTATGCACCCTTAATGGAAGCTTAGAAGCATGAAATGTGAATCACGTGGCTCAAATCGTCAAACGTAATTACAAATGAGAGACGTTTTTCTCATTTGAGAAGAAGAAGAAGAATCTGATATTTTTTATTTTAACATGAACAAACAAAGCTAGACACAAAAAAAATCTACATTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3700
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047401 Nonsense 759 1281 17 25
ENSDART00000134566 None None 609 None 12
ENSDART00000139631 Nonsense 113 635 4 12
Genomic Location (Zv9):
Chromosome 9 (position 49844229)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 49099425
GRCz11 9 48796910
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCTCTATTCCGGACCCGGATGACCAGAGGAGRCAGATAAATGGGATTTG[T/A]ATTTTGTTTGTGGTCATAGGAGTCRTAAGCTTCTTTTCACAGTTCTTACA
Long Flanking Sequence:
ATTGTTTATTTCAACGGAGAGTGGGCTACTTCCGGCGACCTCCGTCTACACGAGCGAAAGCAACTGTAATAAATAAAAATAAAGAGCGACTTTCTTGAGCAACAGCCAATAGGAGGACCAGTAGAGCTCACATGATCTTCTCGTTTGCAGCAGGTCGCCACCCAGAACGCAAGGCAGCTACAAAGTCGCTGCTAGTGTGAATGAGGCATAAAACAAATGCCAGAATAGTTGGCGGTTCATTCAAAAAAAATTTCAGCCGTTAATAAATTACATCTAAAAGGTATAAGAGTTTGGGATTGCAATAAAAAGTAGGAAACTATAATCAGTAGTGGAGTGTGTTTTTGCAGTTGTGTTTAGAAGCTCTAGTAGTGCAGATTCTCACAGTTCACCTTTATTTTAAGTATTTCTTGCTAATAAAGCTTTAACAATATTATGGATGTTTTTCAGACGTTCTCTATTCCGGACCCGGATGACCAGAGGAGGCAGATAAATGGGATTTG[T/A]ATTTTGTTTGTGGTCATAGGAGTCGTAAGCTTCTTTTCACAGTTCTTACAGGTATTTCCTCCATTTCCTTGTGTTTTCGCTGTCTATGCTTGACTGTCTCCCTTAAGTAATGTGAGATGTTGGTTGCAGGGCTACTCGTTCGCTAAATCAGGAGAGCTGTTGACTCGTCGGCTGAGGAAATTTGGATTTCAGGCGATGCTAAAGCAGGAGATCGGCTGGTTTGATGATCCCATGAACAGTCCTGGTGCTTTGACGACCAGATTGGCCACCAATGCCTCCATGGTTCAGGGGGTGAGTGCAGAACACCACAGCGGAATGAACTGCCAACTATTCCAGCTTATGTTTTATGCAGCGGATGCCCTTCCAGCCACAATACAGTACTGGGAAACACCCATCTCACATTCTCACACACACTTATGCAATACAGCCAACTTAGTTAATTCAATTAACCAAAAATCATGACCAAGATAATCATGGTTATAATTTTTCCATAACTGAGC
Associated Phenotype:
Not determined