ZMP

ENSDARG00000011463

Ensembl ID:

Human Orthologues:

F10, F7, F9, PROZ

Human Descriptions:

coagulation factor IX [Source:HGNC Symbol;Acc:3551]
coagulation factor VII (serum prothrombin conversion accelerator) [Source:HGNC Symbol;Acc:3544]
coagulation factor X [Source:HGNC Symbol;Acc:3528]
protein Z, vitamin K-dependent plasma glycoprotein [Source:HGNC Symbol;Acc:9460]

Mouse Orthologues:

F10, F7, F9, Proz

Mouse Descriptions:

coagulation factor IX Gene [Source:MGI Symbol;Acc:MGI:88384]
coagulation factor VII Gene [Source:MGI Symbol;Acc:MGI:109325]
coagulation factor X Gene [Source:MGI Symbol;Acc:MGI:103107]
protein Z, vitamin K-dependent plasma glycoprotein Gene [Source:MGI Symbol;Acc:MGI:1860488]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa28551	Nonsense	Mutation detected in F1 DNA	Not yet available
sa45555	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa28551

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000020921	Nonsense	62	556	2	11

Genomic Location (Zv9):

Chromosome 15 (position 45954185)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	46376118
GRCz11	15	46610335

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAGTGTGACCCGTTCATCTTCTTGTGTTCTTCCAGATGGAGTTCTGGTAC[A/T]GATATAAGAGTAAGTGTTGAGCTGCAATCAGACTATTTTCTTAATCATTT

Long Flanking Sequence:

GTGAAATATGAGGACATTGGTGACGTCCTCATTTCTCAAAATGCTTATAAATCCTACAGGATGAGTTTAATCAGAGAGTAAAGCTAGACACTGACTCCTGTCATGGTTGGGTTTAGGGGTGGGGTGGGGTGAGGGCAATATAATATACGGTTTGGACAGTATAAAATGAATGGAAACTTATGTAATGTCCCCACTTTTCACAAAAACAAACAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTGAATGAGTGTGTATGGGTGTTTCCCAGTAGTGGGTTGCGGCTGGAAGGGCATCCACTGTGTAAAACATATGCTGGAATAGTTGGCAGTTCATTCCGCTGTGGCGACCTCTGGAGAGATAGCGAGTGAGCTGAAGGAAAATGAATGAATGAAGTATTGTTCATTATTAGTAAATGCATGAACTGATGAAGCCTTGTTGTAAAGTGTGACCCGTTCATCTTCTTGTGTTCTTCCAGATGGAGTTCTGGTAC[A/T]GATATAAGAGTAAGTGTTGAGCTGCAATCAGACTATTTTCTTAATCATTTCCACCTCATGATTTGAAGACCATTTCTGAAGCATCAAAACAGATCAAGTGTTTCAGTTTAACAATCTGAGTTTCCCCCTTAAAGACTTATTAATAGCCTGTTTCCACTGAGAGGGGCGGTATAGTACAGTTTGGCACGTTTTTAAGGCTGTTTCCACTGTCAAAAGGTATCTTAAAGCGAATTGTACTGCACCCCTTTTTGGGTACCCTTTGCAAAGGTTACCTAGCACGACAAAAGGGTACCAAAAGGCGGAGCAAGACGTGCAGCTGAATGCTATTGGTTTACAGAGATACATCACTAGCAGGTACACAAGCAGAAAAATGGAAACAAAGGAAGCAGCATTTTTAAATACACAGCCGACACATTGCACTGTAATAATATCGACATATAATAACGAGCCATGATCGACCCGAGCTCAAACAAACCTTGTCGTCGTCTTGATGAACAGCC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa45555

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000020921	Essential Splice Site	327	556	10	11

Genomic Location (Zv9):

Chromosome 15 (position 45965947)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	46387880
GRCz11	15	46622097

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TACCTTATAAATATGTTTATCAGTGTCTCCTGAATGACTGAATGGTCTGC[A/C]GGTTCTTCTTCGGCGTGAGGATGAGTATGGTTTCTGTGGTGGTTCTCTGA

Long Flanking Sequence:

TTGTGTGTGTGTGTTAGTGCAGTATCCCTGTGGGAAGCAGTGGACTGGAGGCATCATGTCACGCTCACTGGATGATGTAAGCCACACCCATGCCGATTATGCAAATCACACCCACTCTTCAACAAGCCCCTCCCATCCATTACATCACAACAGGAGTGCACTGGAAAACTCGACTCACCAGAACCAAACCGAACTCACTGCACCGGACCAGCTGTTGGACACAGGAAGTGACTTCACGGGAGGAAACGAAGACACGCGTATTGTTGGAGGGCAGCTGCAGCGACAGGGCGGGAGTCCATGGCAGGTCAGAAAAATGACTACTGCTTATTTATTTATTTTTAATTTATTTAAATTTGTATTATTGTTATTATTTGAATAATTATTAAAATATTATTGTTATTATTTTTGAACTAAAGAGGAACATTGATTTCATTTATTGAGCTGATAAATTACCTTATAAATATGTTTATCAGTGTCTCCTGAATGACTGAATGGTCTGC[A/C]GGTTCTTCTTCGGCGTGAGGATGAGTATGGTTTCTGTGGTGGTTCTCTGATTAATCAGCGCTGGGTGATAACAGCAGCTCACTGTCTGCAGCAGACACCACACCACATCACCATCGGTGCGTGCGCACACTCACTTTCAGCAAGTCAATTGAAGACTTTTGAAGACATTTTTAAGAGCATTATGAACAGAATTTCAGACTTACACAAGGCTAAACGCTCAGGAAATCTTCTAATGGCTCAATTAAAACATTAAAATACCATAAAAATCAAAAAATAGTGTAAGTAACATTTAAAACATTGGTAGACAAAGAAGACCTGTTTAAATTGATTTAAGACATACAGTACAATAGTTCAGTGAATTTAAACTTTTTAAAGTCTAGAATTGTGTTTCTGTAATTTAACACTTTTCAAGACCCCATGCACTTTATAAACACTCTTCTACAGTCACAGTCACAAATACAGTAACATTTGTGACACATGATACTATTTAAAAGTGGTTT

Associated Phenotype:

Not determined