ZMP
arhgef18
Ensembl ID:
ZFIN ID:
Description:
rho/rac guanine nucleotide exchange factor (GEF) 18 [Source:RefSeq peptide;Acc:NP_999983]
Human Orthologue:
ARHGEF18
Human Description:
Rho/Rac guanine nucleotide exchange factor (GEF) 18 [Source:HGNC Symbol;Acc:17090]
Mouse Orthologue:
Arhgef18
Mouse Description:
rho/rac guanine nucleotide exchange factor (GEF) 18 Gene [Source:MGI Symbol;Acc:MGI:2142567]
Alleles
There are 8 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa16319 | Essential Splice Site | Available for shipment | Available now |
| sa19819 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa16319
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000025841 | Essential Splice Site | 77 | 940 | 5 | 21 |
| ENSDART00000133951 | None | None | 68 | None | 4 |
| ENSDART00000143496 | None | None | 73 | None | 6 |
| ENSDART00000025841 | Essential Splice Site | 77 | 940 | 5 | 21 |
| ENSDART00000133951 | None | None | 68 | None | 4 |
| ENSDART00000143496 | None | None | 73 | None | 6 |
Genomic Location (Zv9):
Chromosome 2 (position 37247495)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 2 | 37544205 |
| GRCz11 | 2 | 37526662 |
KASP Assay ID:
554-6245.1 (used for ordering genotyping assays)
KASP Sequence:
TTGAAAAACTTTTCCAAAGATGCCGWCAAAAGACAGGATGTAATACACGG[T/G]AAGGGACTGTGGTCTWTTTTTKTTNGTTTATTTGTTTATTTGTTTTWCATG
Long Flanking Sequence:
ACCTAGCAAGAACGTTTATTAAACTGATCAGGGTATTTCTATTGCTACAAAAGCTTCAAAAAATGGTCTTTTGAATTAACCATTTTTCAAAAAATCCTTAAAGCATTAATAATTTATTGAGAGAAAATAGCACATCCAGTCTTGACTTTCTTTTTGTTTTTCAGAGCATAAGATGGATGATATTGATTATTACAGAAGCAAGCCTCTGGCAGAGGAATCAAATTTCCAGACCACAAACTATGACGCCATCAGTATTGACGGTTGGACACGTCACCTGTTTAATTGATGTTACATGTGTATTATCATCACAGCACTTGTTTGTTGACACTAAGGCAAGTGTATCTCGTCATCTACACAGAATGCCATTATAATGTGCTGCGTGACGATCTGGAGTCCGATGCTCGGGACTTTGAGGCTCCGACCTGGAGTTTAGCTGTTGACCCACAATATTTGAAAAACTTTTCCAAAGATGCCGTCAAAAGACAGGATGTAATACACGG[T/G]AAGGGACTGTGGTCTATTTTTGTTGTTTATTTGTTTATTTGTTTTTCATGAAATAATTTGAGCCATATTTATTTTAAATGGCTGTTAATGTTGTTCTCGCAGAGCTGATTCAGACAGAAATCAACCATGTGCGGACGCTAAAGATAGTTTTGAATGTGTACATTCGGGAGTTGCGTAACACCCTACAAATGGATGAGACACGACTGGAAAGGCTGTTTCCACAGGTGGAAAACCTGCTGGAGGTGCACCAGTTTTTCCTTGACAATCTTAAACTGCGAAGACTTGACTCTATGGAGCCTGGAAGCTCCCAGAATTACTGCATCCACAATCTTGGGGACATCCTTATCACACAGGTACCATTATTATATAACTGCTGTAGGATATTTATAGATTACAAATGTGATTCCGGACCACAAAAGCAGTCTTATGTGCAAATTGTCCTGAAAGCTGAATACATAATCTTTCCGTTGATGTTTAGTTTATTAGGATGTGAGCGGAGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa19819
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000025841 | Nonsense | 110 | 940 | 6 | 21 |
| ENSDART00000133951 | None | None | 68 | None | 4 |
| ENSDART00000143496 | None | None | 73 | None | 6 |
Genomic Location (Zv9):
Chromosome 2 (position 37247294)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 2 | 37544004 |
| GRCz11 | 2 | 37526461 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAATGTGTACATTCGGGAGTTGCGTAACACCCTACAAATGGATGAGACA[C/T]GACTGGAAAGGCTGTTTCCACAGGTGGAAAACCTGCTGGAGGTGCACCAG
Long Flanking Sequence:
GCCTCTGGCAGAGGAATCAAATTTCCAGACCACAAACTATGACGCCATCAGTATTGACGGTTGGACACGTCACCTGTTTAATTGATGTTACATGTGTATTATCATCACAGCACTTGTTTGTTGACACTAAGGCAAGTGTATCTCGTCATCTACACAGAATGCCATTATAATGTGCTGCGTGACGATCTGGAGTCCGATGCTCGGGACTTTGAGGCTCCGACCTGGAGTTTAGCTGTTGACCCACAATATTTGAAAAACTTTTCCAAAGATGCCGTCAAAAGACAGGATGTAATACACGGTAAGGGACTGTGGTCTATTTTTGTTGTTTATTTGTTTATTTGTTTTTCATGAAATAATTTGAGCCATATTTATTTTAAATGGCTGTTAATGTTGTTCTCGCAGAGCTGATTCAGACAGAAATCAACCATGTGCGGACGCTAAAGATAGTTTTGAATGTGTACATTCGGGAGTTGCGTAACACCCTACAAATGGATGAGACA[C/T]GACTGGAAAGGCTGTTTCCACAGGTGGAAAACCTGCTGGAGGTGCACCAGTTTTTCCTTGACAATCTTAAACTGCGAAGACTTGACTCTATGGAGCCTGGAAGCTCCCAGAATTACTGCATCCACAATCTTGGGGACATCCTTATCACACAGGTACCATTATTATATAACTGCTGTAGGATATTTATAGATTACAAATGTGATTCCGGACCACAAAAGCAGTCTTATGTGCAAATTGTCCTGAAAGCTGAATACATAATCTTTCCGTTGATGTTTAGTTTATTAGGATGTGAGCGGAGTGGAGCAGCAAGAATTTCCACGCTCAAACTATTTTCTCTCTGTCTCCACTCCTCTCCGGGTTTTCCATCCGCATATGTATTTCAACAATAAATGCATTGTAAAAATAAATTCATTTAAGTGTAAGTACACATTAGTTAAGGCCACCTGTAATAAAGTGTGAGCGTTTTTAAAACATGTAGTGTTGCATTACTTAAACTTACT
Associated Phenotype:
Not determined