Busch Lab

ZMP

themis

Ensembl ID:
ENSDARG00000010619
ZFIN ID:
ZDB-GENE-041008-160
Description:
Protein THEMIS [Source:UniProtKB/Swiss-Prot;Acc:A5PF62]
Human Orthologue:
THEMIS
Human Description:
thymocyte selection associated [Source:HGNC Symbol;Acc:21569]
Mouse Orthologues:
9130404H23Rik, Themis
Mouse Descriptions:
RIKEN cDNA 9130404H23 gene Gene [Source:MGI Symbol;Acc:MGI:1921806]
thymocyte selection associated Gene [Source:MGI Symbol;Acc:MGI:2443552]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa36939 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa36938 Nonsense Mutation detected in F1 DNA Not yet available
sa3073 Nonsense F2 line generated Not yet available
sa5946 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa36939
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002928 Essential Splice Site 30 675 1 6
Genomic Location (Zv9):
Chromosome 20 (position 1462375)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 1418240
GRCz11 20 1439066
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAACATCTGCCCCGAGTGTTGCACATCCAGTCCGGCATATACTACCAGG[G/T]TAAGAGGAGATGCTCACAATTACTTTTTCATTTTACTTTTGCTTTTCAAG
Long Flanking Sequence:
TGGAAGCGGAAGTCTCCAGCCAACAAGCTTCCAATGACTCCGCTCACTCGTACGCCAAGAGTAAGGTTAAAGTATAGAGGTTTGTGATTTCAGACGAATCCAATATGAAAAGTAGTTGTGAGATGAGGCTGTAAATGCTGTGTGGTGTTGTATGGATGCTGGTTTCTTCACTCTGTTTTGTGCCTGATGTCACTCAGAGGATGTGGGATGTGTGTGTGTGTGTGTGTATTGTTTGCAGCTCTGCTTGAGTTGTGGTGTTCGAGCTGAACTTCCGCTCCTCCTCTTCCTCCTGTCTCAGTTGTCTGTATTCTCCTGCCATCAGCGGGCCCCTCAGCAGGCCATCAGCGGGGCCACAGGGATCTCCATCAGGCCTCCGCGGGACCATCTGTGGGCCTCAGATAAGCAGAAGATGGCCCAAACACTGCAGGAGTTCACACACGCTCTGGAGGAGAAACATCTGCCCCGAGTGTTGCACATCCAGTCCGGCATATACTACCAGG[G/T]TAAGAGGAGATGCTCACAATTACTTTTTCATTTTACTTTTGCTTTTCAAGAACATTGAGGGAGACCTGGACTAACCCAATGTTGGGTCATTTATTTTCAATTAGTTTAAATGATGCTTTTTGACCCAACATTTTTTTAATCATGCTTTTCAAGCACACTGGGTCAATACAGAGAACCGCATTGTTCTGTTATTGGTTTTTTTTTTGTTGTTTTGTTTTTTTTGATTAAATTTAAAGGATGCTCTTTAACCCAACAGTTGGGTTTGTTCAATAGGGAAAGAGGAGACACTCGTGTTAGTTTTTTATTTTTATTTTTTATTACGCTTTTTAAATACATTGGGGTCAAATATGGACAAACCCAATGTTGGGTTTCACTTATATTTAAATTATGCTTTTTTCTACCCAACAGTTGAGTTTGTTTAACAGGGTAAGACAAGACACTCATATTACTTAACATTTTTTTTTTATAATTCTCATCAAGTAAATTTGGTCAAATATTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36938
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002928 Nonsense 299 675 4 6
Genomic Location (Zv9):
Chromosome 20 (position 1452390)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 1408255
GRCz11 20 1429081
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGAAAACCATTTCAGACTCTCTCCCGACCTGGAGTCCCTTTTCCAGTCC[A/T]AAGAGGTGATTATTCATCACCCTTTCAAAGCCAAACGAATTCTAGCCTCG
Long Flanking Sequence:
TGCTGTTGATGAAATTGACAGTATCTTGCATTAGTTTCACACAGTTTACAAAACCATGTAGTTGGTTTGTTTTAAAGTAGATATTTCAAGCTTTGGATCTGGACTGATTCCCAAAGAACCATCAGTTTATAATGATTGATGATTGGCTCCTGCACAAGAAGGCGGTGCTTTATTCTCCATATTGACCGCTTCTCATTCCCCCATTCAAAACTATTCGAGGGACACATCGTGTGTATTTTATAGTCTTTGCTGATAGAGAGTGTTCCTTTAACCCTGAACTCTTTCTTCCGACAGTCAGCGAGAAAGTTCTGCTCATCCCATCCAATCTGGACGTGGAGGTAGTGGACGTGACAGAACAGTATGATTGCGACTCCTTTGTGCAGCCTTTATCTCTGATGGACGTCTACAAGAGACCACCGCAGTTTTTCCCTGTGCTGGCCAAGCTGTCCAGTGAAAACCATTTCAGACTCTCTCCCGACCTGGAGTCCCTTTTCCAGTCC[A/T]AAGAGGTGATTATTCATCACCCTTTCAAAGCCAAACGAATTCTAGCCTCGGAAATGTGCCAGGAGTCCGCAAGACATTTTCTCATCCCGGAGTCCTACAACGGGCGCTTCAAGCGGCGTCCGCGGCAGTTCTCCACTGCATATGACCTAGAGCGGGCGCGCAGTGAGACCGAGGAAATCCGGGTGGTCGCCACCAAAGACTTCGAGACTGTGTACAGCGGGCTGGCTTCGGTTCAGGCTGGAGAGGAGTTTATAGTGACTAAAGGTCAAAGCTGCGCCGTTTCACACAACGGCACTGAGAAAGTGGCGGATACCTTTGAATGTGTGAAAGTAAAAGCAGAGGGGAAGGAGCCTGTGCGTCTCCCCATGTGTTTGGAGGGGGGATTCATGGAGCTGGTTAAAGACAAGCGTCAGTACACCATCGCAGAAATATGCAGATGGTTCCCGCTGCCCTTCAACGTCAAGGTGTCCGTGCGGGACCTCTCTCTGAAGGCAGACATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3073
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002928 Nonsense 311 675 4 6
Genomic Location (Zv9):
Chromosome 20 (position 1452354)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 1408219
GRCz11 20 1429045
KASP Assay ID:
554-2929.1 (used for ordering genotyping assays)
KASP Sequence:
CCCTTTTCCAGTCCAAAGAGGTRATTATTCATCACCCTTTCAAAGCCAAA[C/T]GAATTCTRGCCTCGGAAATGTGCCAGGAGTCMGCAAGACATTTTCTCATC
Long Flanking Sequence:
TCACACAGTTTACAAAACCATGTAGTTGGTTTGTTTTAAAGTAGATATTTCAAGCTTTGGATCTGGACTGATTCCCAAAGAACCATCAGTTTATAATGATTGATGATTGGCTCCTGCACAAGAAGGCGGTGCTTTATTCTCCATATTGACCGCTTCTCATTCCCCCATTCAAAACTATTCGAGGGACACATCGTGTGTATTTTATAGTCTTTGCTGATAGAGAGTGTTCCTTTAACCCTGAACTCTTTCTTCCGACAGTCAGCGAGAAAGTTCTGCTCATCCCATCCAATCTGGACGTGGAGGTAGTGGACGTGACAGAACAGTATGATTGCGACTCCTTTGTGCAGCCTTTATCTCTGATGGACGTCTACAAGAGACCACCGCAGTTTTTCCCTGTGCTGGCCAAGCTGTCCAGTGAAAACCATTTCAGACTCTCTCCCGACCTGGAGTCCCTTTTCCAGTCCAAAGAGGTGATTATTCATCACCCTTTCAAAGCCAAA[C/T]GAATTCTAGCCTCGGAAATGTGCCAGGAGTCCGCAAGACATTTTCTCATCCCGGAGTCCTACAACGGGCGCTTCAAGCGGCGTCCGCGGCAGTTCTCCACTGCATATGACCTAGAGCGGGCGCGCAGTGAGACCGAGGAAATCCGGGTGGTCGCCACCAAAGACTTCGAGACTGTGTACAGCGGGCTGGCTTCGGTTCAGGCTGGAGAGGAGTTTATAGTGACTAAAGGTCAAAGCTGCGCCGTTTCACACAACGGCACTGAGAAAGTGGCGGATACCTTTGAATGTGTGAAAGTAAAAGCAGAGGGGAAGGAGCCTGTGCGTCTCCCCATGTGTTTGGAGGGGGGATTCATGGAGCTGGTTAAAGACAAGCGTCAGTACACCATCGCAGAAATATGCAGATGGTTCCCGCTGCCCTTCAACGTCAAGGTGTCCGTGCGGGACCTCTCTCTGAAGGCAGACATCTTGGCTGGAACGCCTAGTCTGCACATCGAGGAGGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5946
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002928 Nonsense 336 675 4 6
Genomic Location (Zv9):
Chromosome 20 (position 1452279)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 1408144
GRCz11 20 1428970
KASP Assay ID:
554-3743.1 (used for ordering genotyping assays)
KASP Sequence:
AGGAGTCMGCAAGACATTTTCTCATCCCGGAGTCCTACAACGGGCGCTTC[A/T]AGCGGCGTCCGCGGCAGTTCTCCACTGCATATGACCTAGAGCGGGCGCGC
Long Flanking Sequence:
CAAAGAACCATCAGTTTATAATGATTGATGATTGGCTCCTGCACAAGAAGGCGGTGCTTTATTCTCCATATTGACCGCTTCTCATTCCCCCATTCAAAACTATTCGAGGGACACATCGTGTGTATTTTATAGTCTTTGCTGATAGAGAGTGTTCCTTTAACCCTGAACTCTTTCTTCCGACAGTCAGCGAGAAAGTTCTGCTCATCCCATCCAATCTGGACGTGGAGGTAGTGGACGTGACAGAACAGTATGATTGCGACTCCTTTGTGCAGCCTTTATCTCTGATGGACGTCTACAAGAGACCACCGCAGTTTTTCCCTGTGCTGGCCAAGCTGTCCAGTGAAAACCATTTCAGACTCTCTCCCGACCTGGAGTCCCTTTTCCAGTCCAAAGAGGTGATTATTCATCACCCTTTCAAAGCCAAACGAATTCTAGCCTCGGAAATGTGCCAGGAGTCCGCAAGACATTTTCTCATCCCGGAGTCCTACAACGGGCGCTTC[A/T]AGCGGCGTCCGCGGCAGTTCTCCACTGCATATGACCTAGAGCGGGCGCGCAGTGAGACCGAGGAAATCCGGGTGGTCGCCACCAAAGACTTCGAGACTGTGTACAGCGGGCTGGCTTCGGTTCAGGCTGGAGAGGAGTTTATAGTGACTAAAGGTCAAAGCTGCGCCGTTTCACACAACGGCACTGAGAAAGTGGCGGATACCTTTGAATGTGTGAAAGTAAAAGCAGAGGGGAAGGAGCCTGTGCGTCTCCCCATGTGTTTGGAGGGGGGATTCATGGAGCTGGTTAAAGACAAGCGTCAGTACACCATCGCAGAAATATGCAGATGGTTCCCGCTGCCCTTCAACGTCAAGGTGTCCGTGCGGGACCTCTCTCTGAAGGCAGACATCTTGGCTGGAACGCCTAGTCTGCACATCGAGGAGGAGATCTCAGACCCGTGTGTCCTGGTCTCAAACACGGACCTCTCAGACTTCAGGGAGGTGCCAGTAAACCGTACAGAC
Associated Phenotype:
Not determined