Busch Lab

ZMP

LOC100333601

Ensembl ID:
ENSDARG00000010556
Human Orthologue:
MMP25
Human Description:
matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:14246]
Mouse Orthologue:
Mmp25
Mouse Description:
matrix metallopeptidase 25 Gene [Source:MGI Symbol;Acc:MGI:2443938]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa41941 Nonsense Mutation detected in F1 DNA Not yet available
sa35194 Nonsense Mutation detected in F1 DNA Not yet available
sa41942 Nonsense Mutation detected in F1 DNA Not yet available
sa22003 Essential Splice Site Available for shipment Available now
sa22004 Nonsense Available for shipment Available now
sa22005 Essential Splice Site Available for shipment Available now
sa41943 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa41941
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081382 Nonsense 6 573 1 10
Genomic Location (Zv9):
Chromosome 12 (position 4941311)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 4224028
GRCz11 12 4260796
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCTGTGAATAAAGGTCTCCACCAGCACACACATGAGTTTCTCAGGATA[T/G]CTTGGTCTGGTTTACCTGACCTGCCCTATGCTTGTGTTCTTCTCTGCGGT
Long Flanking Sequence:
CAAATTTTTGAAGAATGTTGGATGAAAAAAAAAACATTCATCTAATTTTTTTCCCCTATTGATTGGCTACATTCTTCACAATATCTTCCTTTGTGTTCAACAGAAGAAAGAAACGCATGTAGTCCTCACTCGTTTTTGGGTGAACTGTCCCTTTAAATCAAGTTACAGCTGAATAATTAATGTTAATATTGATTATGTATTTTAATCCAGTTAAGCAATGTTTATTGAATCTTTAGGGAGTAAGAGATTCTCATAGAGAGGATTTTTTCTGAGTAAAGCATATGTGTGTGTGTGTGTGTGTGTGTGTGCGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGACTCATTGATTGGTTCAGCCCTGCCTAGTCCTAAAGAGACAAACTGAAGAAGCCAGAAAGACGCATATAACGGTGTGAAAGCATAAAGGCAACACTCATCTGTGAATAAAGGTCTCCACCAGCACACACATGAGTTTCTCAGGATA[T/G]CTTGGTCTGGTTTACCTGACCTGCCCTATGCTTGTGTTCTTCTCTGCGGTTCATTCGGCTCCGGTAAAGGATCAGTATTCTCGGGGTGTGGTGAGTTCTTTACTCTGATTTTCTATAAATTGAACACTTTTACAGATAGACGAACAAACACTGTATAAGTGGATCTGGTTGATGTATTATAAGTAGTGCACTTTTAAAAAAGGGGGGAGGACAACATAATTGTTTTATTTTCAATCCACTTTAATTTGTACAACAACAATTAAACTGTTAACTTTATAAATTTGTGTTGGGACAACGTGGAGTTGTGTGGAACATTTTTACAGTGCATGTTATTAGTTCAAATCCCTGTGTGACAGATTGTTAGTGGAATTATAAGGATTTTATATATTATTTTTGAAGAAACTACTGTACAGTAACTAGCTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35194
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081382 Nonsense 75 573 2 10
Genomic Location (Zv9):
Chromosome 12 (position 4943415)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 4226132
GRCz11 12 4262900
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGACGGCATCGAGAGAGCCATTAGAGAAATGCAGAGATTCGCTGGACTC[A/T]AGGAAACAGGCAAACTCGGTACATAATTCTGATCACACATAATTACCTGT
Long Flanking Sequence:
CACCAAACATCTTTAGAAATAGAAGATAACACATTTTAATTCATGCAAAAATATAGCAATTTCCAAGCAAGTATGCCTACTTTTCATTTCTCTTGATTTTTTTTCTCTTTTTACATTTTTTTTATTTAATATTTTTCCCTAACATACAAATTTTGGTGTTTTAATTTTTGGATAATACGCTACTCTGTTAAATAAGCTTCAGATTTTGCTTCAGTATTGACTAATCTAATATATATGCACAAATATCATTTTGTAAAGCTTCCTATAGAAAATATTAATTTAAAAGAGTGATTTGTGAGGGGTGTACTCGTTTATGTTGAGCACTGTACATTGAATTATTGATTATCGGCATATGTCTAGTCACATGGTATTTCTCTGACCTGTAGGACTGGTTGAGCCGGTATGGATATCTGCCTCCTCTAGACCCGCGCACAGGACAGCTACAGAGCAAAGACGGCATCGAGAGAGCCATTAGAGAAATGCAGAGATTCGCTGGACTC[A/T]AGGAAACAGGCAAACTCGGTACATAATTCTGATCACACATAATTACCTGTAAAAGAGCTTGCAAATCTATTCACTAACACCATCTTGTTATTCAGTTGTACCAAAGATTGTACCCTTTGCGATTGCACCCCTCCCCTCTTTTTACAGTAATAAACGTTAATTTCAAAAGCGTTTAAGTACTTTTGCATTTGGCTGTAAATTTACAGTATTTTATTAAGTGTACACTGTAAAGAACATCCTTAAATTAGCAGTTTTTCATATTTTGTGCTTCATGTTTTTATTTTTTATGTTTATTTATGCTTTTAAACTGCATTATGGGACCTTGGACTTTTTTTTACAACTTCTAACCTTGAAAAGTTGGGAAAAAAGTGACTTTTAGAAACATTTTTAATAGTTTAAAGTGATATATTGTGTGCGTTGGTGTTGTAATTACACTACAAAAACCTTGTAATTAGCTGCCAGTACATTTTCTGTTATTCTACAGACTTATTTCTCTATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41942
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081382 Nonsense 109 573 3 10
Genomic Location (Zv9):
Chromosome 12 (position 4946788)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 4229505
GRCz11 12 4266273
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGTTCTCTGCCAGACATCATAGGCATTGAGGACAAGCTGAAAAAGCGC[A/T]GAAGGAAAAGATACGCAACCACTGGGCTCCGCTGGACAAAGTCTGACATT
Long Flanking Sequence:
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAGATAGATAGATAGACAGAATAGATAGATAGATAGATGGATAGATAGATAGATGGATGGATGGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATATGTAAACTGTAATTTGATATATGTAAATGTAATAATGAGACTTTTTATTCCTAATTCTGTGGTTGCTGGCTTCAGTAAATCTCTTCTAGAGAAAGAGTTCTTCCATTGTCCCTCCTCCTCCTCCTCGTGTGGGTTTTATTACATGTTCTGAAATGGGCTCTGTGTCTCTGAAGTCTATATATTGATCCGGTACCTTCTGCCGTTGTGTTTCCAGACAGTGACACTCTGACGCTGATGAACACACCACGATGTTCTCTGCCAGACATCATAGGCATTGAGGACAAGCTGAAAAAGCGC[A/T]GAAGGAAAAGATACGCAACCACTGGGCTCCGCTGGACAAAGTCTGACATTACATGGAGGTCTGTATGATCGAGATATGATCACCGCTAACCAAACTAACAAGCATGACTAACTGAAAATCAAGCACTTTATATATGCAAAATATTACTCCAGTAAAAGTAGAATGATGGAGGCACGGTGGCTCAGTGGTTAGCACTGTCACTTTACAACAAGAAGGTCACAGGTTTAAGGGCCAGTTGGCATTTCTGTGTGGAGTTTGTATGTTCTCCCAGTGTTGGTGTGGGTGTCCTCCGGGTGCTCCAGTTTCACCCACAGTCCAAACGCATGCGCTATAGGTGAATTGGATAAACAAAATTGGCCGTAGTGTATGAGCGTGTGTGGGTGTATGGGTGTTTCCCAGTACTGGGTTGCAGTTGTAAGGACATCCGCTACATAAAACATATGGTGGAATAATGGGGTCGCCACAGTGTTAAATAAGGGATAATAATGTTAAATAAGGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22003
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081382 Essential Splice Site 225 573 5 10
Genomic Location (Zv9):
Chromosome 12 (position 4949219)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 4231936
GRCz11 12 4268704
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTCAGCCACTTATCTACACATGTCCTGTTCTTATTCTCTGTATATTTTC[A/T]GATGAAAGCGGCACTGATTTGTTTGCGGTTGCGGTGCATGAGTTTGGTCA
Long Flanking Sequence:
CTAGTTCACCTTATTAACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGTATAGAAGTGTCTTAAAAAATATCAAGTAAAATATTATTTACTGTCATCATGACAAAGACAAAAAAAATCTGTTATTAGAAATAGGTTTTTAAAACTATTATGCTTATAAATGTGCTGAAACAATCTTCCCTCCATAAAACAGAAATTGGAGAAAAAAGTAAACAGGGGCACTAATAATACAGGGGGGCTAATAATTCTGACTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAGTACATTTATTTACTAATGTTATTTATTTATTATTAAATTAATAAGTAAATGCATACAATAAAAGTTATTGTGAACCAGCAACTGTTGGGCTACCAAGACTTTCTCAAATTTGTATTTATTTATTTATTTTGTGCTCAGCCACTTATCTACACATGTCCTGTTCTTATTCTCTGTATATTTTC[A/T]GATGAAAGCGGCACTGATTTGTTTGCGGTTGCGGTGCATGAGTTTGGTCATGCTCTGGGTCTTTCTCACTCCTCCTCTTCCCCCTCCATCATGAAGCCCTATTATCAGGGCTCTGTTGGAGATGTAGGATCCTACATTCTTCCGGACGATGACCGTGAGGCCATTCAGTCACTCTACGGTATTTTTCTTTTCCCTAATATATGTTTAACGGGAAAAAAAAGGTTTTCAACACATCTCTAAACATCATAGCTTGTTCTGTAGACAATCAAAACATATATTGCTTAAGGGGGCTAATAATATTGAGAAATTTAAACTGCTTTTATTCTAGCTGAAATAAAACAAAATAAAACAAATAAGACTTTTTTTCAGAAGAATAAATTTGATAGGAAATACTGTGAAAAAAATCCTTGCCTTGGTAAACATCTTTTGGAAAATATCTGAAAAAGAAAATTCAGAGGAGTCTAATAATTTAGACTTCAACAGTTGGTGGTTGATCCACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22004
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081382 Nonsense 258 573 5 10
Genomic Location (Zv9):
Chromosome 12 (position 4949321)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 4232038
GRCz11 12 4268806
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTCTGGGTCTTTCTCACTCCTCCTCTTCCCCCTCCATCATGAAGCCCTA[T/G]TATCAGGGCTCTGTTGGAGATGTAGGATCCTACATTCTTCCGGACGATGA
Long Flanking Sequence:
ACAAAGACAAAAAAAATCTGTTATTAGAAATAGGTTTTTAAAACTATTATGCTTATAAATGTGCTGAAACAATCTTCCCTCCATAAAACAGAAATTGGAGAAAAAAGTAAACAGGGGCACTAATAATACAGGGGGGCTAATAATTCTGACTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAGTACATTTATTTACTAATGTTATTTATTTATTATTAAATTAATAAGTAAATGCATACAATAAAAGTTATTGTGAACCAGCAACTGTTGGGCTACCAAGACTTTCTCAAATTTGTATTTATTTATTTATTTTGTGCTCAGCCACTTATCTACACATGTCCTGTTCTTATTCTCTGTATATTTTCAGATGAAAGCGGCACTGATTTGTTTGCGGTTGCGGTGCATGAGTTTGGTCATGCTCTGGGTCTTTCTCACTCCTCCTCTTCCCCCTCCATCATGAAGCCCTA[T/G]TATCAGGGCTCTGTTGGAGATGTAGGATCCTACATTCTTCCGGACGATGACCGTGAGGCCATTCAGTCACTCTACGGTATTTTTCTTTTCCCTAATATATGTTTAACGGGAAAAAAAAGGTTTTCAACACATCTCTAAACATCATAGCTTGTTCTGTAGACAATCAAAACATATATTGCTTAAGGGGGCTAATAATATTGAGAAATTTAAACTGCTTTTATTCTAGCTGAAATAAAACAAAATAAAACAAATAAGACTTTTTTTCAGAAGAATAAATTTGATAGGAAATACTGTGAAAAAAATCCTTGCCTTGGTAAACATCTTTTGGAAAATATCTGAAAAAGAAAATTCAGAGGAGTCTAATAATTTAGACTTCAACAGTTGGTGGTTGATCCACACAGAACAGCGTATAGACTTAAAGGGGTAGTTCAAAGATAAAATTAGAAATCTGTCGTCATTCACTCATCCTTTATAGGTTTCTGTAACACTTTAGTTTAGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22005
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081382 Essential Splice Site 341 573 7 10
Genomic Location (Zv9):
Chromosome 12 (position 4953378)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 4236095
GRCz11 12 4272863
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGTTTTGATGCAGTGGCGAACCTCAGAGGAGAAGTTTTCTTTTTTAAAG[G/A]TACAGTGCAATAACAATTTCTACAATGTAGAGATTTTGTAAACCAGGGGT
Long Flanking Sequence:
CATCTCTGGGAAACATATTACTCATTTTTTTATTTATTAATTAATTTATCATTTAGTAATTTTGTTCTAGAAAATAAAGCAAATCAACACCAAATTTAATAAATAATGCATCATTTAGAAAATTTCTAAAAGATTAACAATCTTTGCATTTCCTAATGTAATCAATCGGCTGCATGGGAATATAATGTGATAGCGATTTTTTTTTACTAAATTCACCTGAAGTGTATTGCATTACATCAAAAAAGACAGAAAAATTTACATTGTACCATAATATTTCAAATTCAAATGAAATAGTTTTTAAATTTCTATCAGTTTTTATAGCGTTTAAAAAACAGCAACATTTTTGCACTTTCTCAAACACTCAATACTATCCAGTTAAAAGTATTAACAAATTCTCTGACCTTTCTGTTTGTCTAGACCTGATCCGTCAATCCAGAATCGCTGTGAGGGAGGTTTTGATGCAGTGGCGAACCTCAGAGGAGAAGTTTTCTTTTTTAAAG[G/A]TACAGTGCAATAACAATTTCTACAATGTAGAGATTTTGTAAACCAGGGGTGCGTTTTCGAAAACCATCATTAGCCAACTAAGGTTGTTATAAACATAGTTCATTGATTTGGCGTTTCCCAAATCCATCGTTTCAACGAACATTCGCAAACTGCGTCGCAAACTTGTACGCTTGCAACTACACCTCTGGAGCTGTAGTTAGAAACATAGTTCCTGGCTATGTGCTATTCCAAGTTATCCCCCCTATGCCCTATTTGTTTAGAACATTTTAACATTTAAACTCTTATTGGAATTTTTTGCCAATTCCATGCGTGTTCAATAAGAAAAGGTCTGGAGAGGGTTTTCTTCAATGCCAAAAATATTAGTAATTTATTAGATACAAATGAATAATTCGATGACAGAGCTCTGGGTTACGTTACCCCAATGCAATACAAGACTTACATTTAAGAGGTTCGCAACTAACATGCATTTCCTAACTCCAGCATATATACACAACTGATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41943
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081382 Essential Splice Site 392 573 8 10
Genomic Location (Zv9):
Chromosome 12 (position 4956290)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 4239007
GRCz11 12 4275775
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGATGCAGTCTATGAAAGAAAGGTGGACAACGCAATCATCTTCTTCATAG[G/A]TTGGTCTCTCTTTATTTGCAGTGAAAAATATATGGAACAATTGATTTGAA
Long Flanking Sequence:
TGGAGTAAAAGCTGTCCATTGGATCTCATTACTGTCGTGATGGCAAGCAGCTGCTTTGTTTTTTATTTATTTATTTTAAAAGGGCATTAAAGCTGAGATACAACCTGAAAGACGACAATACAGCACTTACTATCACAATCATCAACACTTTTAATAGTTTATTTTACAGACTTATAATACGCTCTTGTTCTATTGGAGTTTTCATTCTAAATGGCCGCCGCACCATCTAGTGGCTGTTTCCCAAATTACACTAGAGTGTCGCCTCTTGGTCATTCTAAGCTCTTTGGCTCAATGTTTAAACTTGCTTGTGGAAAAACATTGTGTTGTTACTTGTTGCTCTTGCCCAGGTCCATATTTCTGGCGAATCCAGCGGACGGGTTCTCTAGTGTCCTTTCAGCCTGCTCACATTAAGAACTTCTGGATGGGTCTTCCTCCAACCACCAATAAGGTAGATGCAGTCTATGAAAGAAAGGTGGACAACGCAATCATCTTCTTCATAG[G/A]TTGGTCTCTCTTTATTTGCAGTGAAAAATATATGGAACAATTGATTTGAAAATTATTTTTAGTAAGTTATGCGTAACTTTTCCCACATAGGCTCACAGTACTGGGTATTTAAAAACACGGAGGTGCTTCCTGGCTATCCACGTCCATTGTCTGACTGGGGAATGATCACTCAAGATGGAAGGAAGGTGATGAGAGTGGATGCAGCCTTTATTTGGGCTCATAATGGAAAAACCTACATTTTCAGCGGTGGAGAGTTCTGGAGGTTCTCTGAAGGCAGGGAGACTGAGCTGCGCGGTCCGGACACAGGCTATCCCAGAAACACCAACCTCTGGAAGGGGGCGCCAAGTAACCCGGATGACGTCATCACCTGGGGACAAGGTAAAGTAATAATATAGAGGAAATCAGTTTGCCTCAAACGCATTTTCTAAGGTGAAACAACATTTAAGAAATTTATTCAGTGCTGATTCTGTGATTTTCTAAATTTATCACTATTCTCACTT
Associated Phenotype:
Not determined