ZMP

jak3

Ensembl ID:

ENSDARG00000010252

ZFIN ID:

ZDB-GENE-070725-4

Description:

Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;Acc:B0V237]

Human Orthologue:

JAK3

Human Description:

Janus kinase 3 [Source:HGNC Symbol;Acc:6193]

Mouse Orthologue:

Jak3

Mouse Description:

Janus kinase 3 Gene [Source:MGI Symbol;Acc:MGI:99928]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa45312	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa45312

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000049469	Essential Splice Site	190	1103	4	23

The following transcripts of ENSDARG00000010252 do not overlap with this mutation:

ENSDART00000138151

Genomic Location (Zv9):

Chromosome 8 (position 13908799)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	13354143
GRCz11	8	13391848

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTGGCCAAAGAGAGAAACCAGAGCCTTGCAGAGATCTGCAATACAACAAG[G/A]TATGTTACAACAACAACATTTAGAACATCTTATAAACACTCATCGGCCAC

Long Flanking Sequence:

GCTAATAATTAATAATACACATTCACATTGATTTTTAGAGTGCAAATAAAGTTAGAAAGTAAAATGTGTGTTTGAATTAACAAATGAAATTAGATGATTGTAAAGCTTTTGTGTGTATGTTTAAGGTTTTTCTTCTCAAGCTGGTTTGGTCAAGAGTCGAGAGCATCGTACCGCTTTAGCCTCAGCAAGGGACGAATCTTTGCTGTGCTGGACTATGCTGTCATTGACTATGTTTTTGCTCAAGTAATAACTATTATATGTAACTATTACTATTAGATTTAAATCATTATAAAAAGGTAGCATAAGTTTCTGATTTAAAATCATTTACCTTACGGAGAAGTTTTCCTGTTTCAGTCCCGCAGTGATTTTGTGACTGGATGTGGTGGGATTTCTCCTGCATTGAGTTTGCAGCAGGAATGTTTAGGTTTGGCAGTGCTGGATCTGTGGCGTTTGGCCAAAGAGAGAAACCAGAGCCTTGCAGAGATCTGCAATACAACAAG[G/A]TATGTTACAACAACAACATTTAGAACATCTTATAAACACTCATCGGCCACTTTATTAGGTACCACTTTATTAAGTGCAACTGCTGGCATATTTCTAATTAGCCAATCACATGGCAGCAACTCAATGCATTTAGTTACGTAGACATGGTCAAGTCGATCTGCTGCAGTTCAAATCGAGCATGAGAACGGGAAAGAAAGGTGATTTAAGTGACTTTGAATGTAGCATGGTTGTTGATGGCAGACGGGCTGGTCTGAGTATTTCAGAAACTGCTGATCTACTGGGATTTTCACTCACAACAATCTCTAGGGTTTACAGAGAATGGCCTGAAAAAGATCAAATATCCATTTGAGCGGCAGTTCTGGGGGCGCAAATGTCTTGTTATTGCCAGAGGTCAGAGGAGGATGGCCAGATTGGTTCTTCTAACTGGTAGAAGGCAACAGTAACTCAAATAACCACTCGGTACAACTGAGGTATGATGAAGAGCATCTCTGAAAGCAGAA

Associated Phenotype:

Not determined