Busch Lab

ZMP

ldb1a

Ensembl ID:
ENSDARG00000010137
ZFIN IDs:
ZDB-GENE-990415-135, ZDB-GENE-990415-138
Description:
LIM domain-binding protein 1-A [Source:UniProtKB/Swiss-Prot;Acc:O73715]
Human Orthologue:
LDB1
Human Description:
LIM domain binding 1 [Source:HGNC Symbol;Acc:6532]
Mouse Orthologue:
Ldb1
Mouse Description:
LIM domain binding 1 Gene [Source:MGI Symbol;Acc:MGI:894762]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa38946 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa35507 Nonsense Available for shipment Available now
sa42216 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38946
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002698 Essential Splice Site 127 359 None 11
ENSDART00000015773 Essential Splice Site 83 374 None 11
ENSDART00000126845 Essential Splice Site 82 375 None 11

The following transcripts of ENSDARG00000010137 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 28961735)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 28607683
GRCz11 13 28738133
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATAGCCTGTACATTAATTCTGTACTGAAACCAAATTTTTTTCTTGATTTC[A/T]GCTATTGGGAGAACGTTGATCCCTCGGTACTTCAGGAGTATTTTTGAGGG
Long Flanking Sequence:
TATGGAAATCAAACAGACTACAGAATATTTGAGCTCAACAAAAGATTACAGAATTGGACAGAGGTAAGAAACCAATTAGTTCATATTGGTTTAAATGGGGAGCAACAGAATTTTCATTTTCTGTGAAGAGAACAGTAGTTTATTTACATGCATGCAAATCATGCAAAGTCATGAAACGTGTTGCTTTCATTTATTTTATTTTGAAACAAAGCTTATGGATGTATTGTGTTTTTATGCTTTCTCAGCAGGACTGTGACAATTTGTGGTGGGATGCGTTTACTACAGAGTTTTTCGAGGATGATGCAATGCTGACTATCACTTTCTGTCTAGAAGATGGACCCAAACGATATAGTAATGTTCTGCTTTGTAAAGTCATTTCTGTAATTTTGATTTGTTTGCATTTGGCTTGAAATGCTTTTAAAAATAAATAAATAAATAAGGAAACCCATTATAGCCTGTACATTAATTCTGTACTGAAACCAAATTTTTTTCTTGATTTC[A/T]GCTATTGGGAGAACGTTGATCCCTCGGTACTTCAGGAGTATTTTTGAGGGTGGCGCTACTGAACTCTTCTATGTGTTGAAACATCCAAAGGAGTCGTTCCACAATAACTTTGTGTCCCTGGACTGCGATCAGTGCACCATGGTCACACAGAACGGCAAACCCATGTTCACACAGGTATCGTTTTCATCTGCGTTTCTGGCCTTTATTTTAACACTAACATCACTAAGCATATTCTTTTAGGCCCAAATATAGTTATAGCAAAGTTTGATTGATTGTTCTGTTTCGAAAAGGGGATTCAAATTGTTACAATGTTGCTTTTTGTTCTTGGTGCAGTTCGCTTTCACACACCAAAGCTTCTAAATTGACCAAAATAGTTAAACAAGTCACATGCGAGTAATCTCCTCAAATTGGTTAAAGTTTGCTTTCTTTTCCGGGATTTCACTTACACTTGTCATACGTCGTTATTTTAATTTATGACGATGAAAAAGAGATCAGAGGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35507
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002698 Nonsense 305 359 10 11
ENSDART00000015773 Nonsense 261 374 10 11
ENSDART00000126845 Nonsense 260 375 10 11

The following transcripts of ENSDARG00000010137 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 28966314)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 28612262
GRCz11 13 28742712
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTGATCTGTCTCTCTTCAGCCGAGCCAGCAAGACAAGCCCCCAACAAG[C/T]GAAGGAAACGAAAAATGTCCGGCGGGAGCACAATGAGTTCTGGAGGGGGC
Long Flanking Sequence:
AAACCAATAGCGTTCAGCTGCGCATCTGGCCCCCTCTTTTGGTACCCTTTACGAAGGGTGACCAAAGAGTGGTATGGTACGGTTCAGTACGCCTTTTGACAGTGAAAACAGCCATTGGACCGTACCGTACCACTCTGTGGAAATGGGCCATTAGACTAGAAACGAGACAAAAATTCTAAGAAAGTTAAGTTCCTACTCAACTATAATTCAGACTCAACATTGCATATCTTGCACTGTGACTATTGCGGATGCACACATTGCGATTTTGTTTCTGAAACGATATATCGTGCAGCCCTACTTTATACTCTATACCACTAGGTTTTACCCATTTAGTTTCAGTAAAATGGTTCTTTTTAATGTGTTCTAATTACATGCTTTTAATATGTATATAAAATCACTTTTGTACATTTAAATTTGTCTTTCATGCGTATAAATACCTGAAATTTCCCCCTCTGATCTGTCTCTCTTCAGCCGAGCCAGCAAGACAAGCCCCCAACAAG[C/T]GAAGGAAACGAAAAATGTCCGGCGGGAGCACAATGAGTTCTGGAGGGGGCAACAACAACAACAGCAACAGTAAAAAGAAAAGCCCAGCCAGCAGTTTTGCGCTCTCCAGCCAGGTACCTGTAAGCATCACATTTTGATGTCCGTTTTTGAGCTGTTGGGAGATGGGTGGAGGGTGGAGGGTGGACCACGATACTACATTAATACTAGGAAGACAGACCCAACATAGCGACAAGTGGACATGATCCAATGCTGGGCAGTCCCTGGTCCTTTAGGGCTGCAGGTCTGTGGGGTTTTTGTGCTTTTTGTCAGTCTGTTGGGTGTTTTGAGCTCCAGAGACGCAGCCAACACTAGAGACCCGAGGTGGAATTAACCCGTGCAGCACTCAAGGATCCGGGATGCCCACCATGGCAAAGCTATTTAGTTTTTCAGCATGGTGAACGTAGGCTTGTCACATACAGCAAAGCACAGAGTTCCTGTAGTGGCCAGGATAGTCCAGGTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42216
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000002698 None None 359 None 11
ENSDART00000015773 Nonsense 328 374 11 11
ENSDART00000126845 Nonsense 329 375 11 11

The following transcripts of ENSDARG00000010137 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 13 (position 28967002)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 28612950
GRCz11 13 28743400
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGGAGTTCGGGGACGAGGATGAGCGGCTCATCACACGGCTGGAGAACACA[C/T]AGTTTGATGCGGCCAATGGCATCGACGACGAGGACAGTTTCAACAGTTCC
Long Flanking Sequence:
CGATACTACATTAATACTAGGAAGACAGACCCAACATAGCGACAAGTGGACATGATCCAATGCTGGGCAGTCCCTGGTCCTTTAGGGCTGCAGGTCTGTGGGGTTTTTGTGCTTTTTGTCAGTCTGTTGGGTGTTTTGAGCTCCAGAGACGCAGCCAACACTAGAGACCCGAGGTGGAATTAACCCGTGCAGCACTCAAGGATCCGGGATGCCCACCATGGCAAAGCTATTTAGTTTTTCAGCATGGTGAACGTAGGCTTGTCACATACAGCAAAGCACAGAGTTCCTGTAGTGGCCAGGATAGTCCAGGTCTAGTTCCTGCGATGCGGTGTACAGAAAGCCACCGCGTCCCCTCCTTCGGAGGACCCCCGGGTGTCGGGGATAATGTTTGCGCCCCTTCCTGTCCCCTGCAGGACGTGATGGTGGTGGGAGAGCCCACTCTGATGGGAGGGGAGTTCGGGGACGAGGATGAGCGGCTCATCACACGGCTGGAGAACACA[C/T]AGTTTGATGCGGCCAATGGCATCGACGACGAGGACAGTTTCAACAGTTCCCCTACCATGGGCACCAACAGCCCCTGGAACAGCAAAGCTCCCTCAAGCCAGCAGGGCAAAAATGACAACCCCAGCTCTCAGTCGTCGCAGTAGAAGTATTAGGGGCTAGTAAAAGGCTCGTTCATTCCAGGCCTTGACAAGTCCTCATTTGCTGAAATCAGCCCTCCTCCTCCTCCTCCTCAGTCACCATCAGACGTGCCGCTTTTTTTTCGTAAATTATTCTTTTTTTGGTTTGTTTTCTTTGAGAATCATTTTGCAACACCGTCTGTTTCTGTGTCTCGATCAGGCTTAGCGATCAGGCTGTGGGTTATTGTTCCAACCTCGGGTCTCTCTTGTGCGTGCTGTGCTTTGACACGCATGGCCGTTTCTGTTGTGCTCACTTGACAGGAAAGGATCACTTTTTTTATCTCACCGTTTATTGTGTGCACCTCAGATTCAAACCCCAACCGC
Associated Phenotype:
Not determined