ZMP

slc1a6

Ensembl ID:

ENSDARG00000010096

ZFIN ID:

ZDB-GENE-071004-45

Description:

excitatory amino acid transporter 4 [Source:RefSeq peptide;Acc:NP_001103173]

Human Orthologue:

SLC1A6

Human Description:

solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 [Source:HGNC Symbo

Mouse Orthologue:

Slc1a6

Mouse Description:

solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 Gene [Source:MGI S

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa38824	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa35013	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa35014	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa38824

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000012789	Essential Splice Site	202	560	5	10

Genomic Location (Zv9):

Chromosome 11 (position 6198362)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	6166545
GRCz11	11	6163800

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GTACAGAAATATGTTTCCACCAAATTTAGTTGAAGCCTGCTTTAAACAGG[T/C]TTGTACATCTTTGAATGCAAACATCTTTCTAATGCATGTGTCAGTACATC

Long Flanking Sequence:

AGTATGTGTGGAATGAATGTATATATATTATACAAGTTTCATGTCTTGAATGGAATTAGTGAAATAAATCAACTTTTAAAGATATTTTAAGTATTAGACCAGCACTAGTACATTCTCATCTAGAGATATTTTGGTGCTGCATGTTTTTGTTGCTGTTGTAGGAATCTCATCTTTAGACAGCAAGGCCTCTGGGAAGATGGGAATTCGGGCCATCGTTTACTACATGGTGACCACATTAATTGCAGTTTTCATCGGCATTGTGATGGTGATCATCATCAAACCGGGTAAAGGCAGCAGAGATAGTCCAGTGGCCTCTAGTGGCAGCATTGAACCAGTGCAGGCCGCAGATGCCTTCCTGGACCTTATAAGGTGGGGAGAAAGTTTCACTTGACTATTGCAGTCTTTGTTTATTTAAAAAAAAAAATTACCAGATCTGATTTTCCTCTTTTCGTACAGAAATATGTTTCCACCAAATTTAGTTGAAGCCTGCTTTAAACAGG[T/C]TTGTACATCTTTGAATGCAAACATCTTTCTAATGCATGTGTCAGTACATCTATGTTGGTCCTGTAACAACATTCTAATCAGCAAATCAGAATTAAAGGATACGTTTAATTTAAGCTTAGGCTTAGGTTACGTTAGGGTTATGTGCTTCTTCAGGATTATATCCAACTATTATTCCTCATTGATTTTGGGTATAATTTACAGTTAAGTATGGGTTAGGGATTAGGTCTGGATTACACTTTCGAATAAAAATGCCATTACAGGATCAACATAAATGCTAGATAAAATCATACTCACTGAATATACTCTGTACAATATTTTTTTGTGAGTTTGTGATAGGATGGAGATACAGACTTCGAATTGTGAGTTCATAACTATCTAGGAAGCAACATCTGAATAATGTGCTGTTTTTGGTTTGTTTAGATGTGTTTGGTTCACATTGTGCTCATATTTCAGTTACAGCAAGACACTGCAGGGTGAATAGTGTACGAATTATCTAATGA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa35013

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000012789	Essential Splice Site	307	560	6	10

Genomic Location (Zv9):

Chromosome 11 (position 6200819)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	6169002
GRCz11	11	6166257

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCGACTGCCTGAATGAAGCTATTATGCGCTTGGTGGCCATCATAATTTGG[T/C]TAGTGTCTGATTAGGATGTTATATAGGCAATCAGGCAGTTATTTTTACAG

Long Flanking Sequence:

TACCCTTCTAGCCACAATCCAGTTCTAAGTGTCCATTCATACTTATTCAAATAAACTGCACTAACAGAGCAATCATTTGTTTTAATGAAATCAAAGCTCTAAATTCTGAACACAACCTTTAATTTTATTCCAAAAAGCTTTCATAGATCAAATATATCACTAATCATCCCATTTCATTTTTGCAGTACAAAACACTATACAAGAAAACCGTGCTGACAAAAAATGTCACCATCGTGGTCAATGCGACAGAGAACGTCAACTCTACTGATCTCAGCCAAGTGTCCAACTTCAGCCCAGTCTTGCAGACCATCCAGGAGACGGTGGAGGAGGCTGTCCCAGTCTCTGGCTCCTCCAATGGGGTGAACGCCTTGGGCTTGGTGGTTTTCTCCATGTGCTTTGGATTAGTGATCGGAAACATGAAACAGCAGGGCCAGGCTCTCCGGGACTTCTTCGACTGCCTGAATGAAGCTATTATGCGCTTGGTGGCCATCATAATTTGG[T/C]TAGTGTCTGATTAGGATGTTATATAGGCAATCAGGCAGTTATTTTTACAGTGACATGACACTTGATTCTCTTCTTTTATTTATTTATTTTTTATATGATCAGACCTTTTTGTGCAAGGTAAGTTTACTTTAGGTTGTAAAATGTGGCAAAACTTAAATATCATTTGATAAAAAAATAAATGTAAATATGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATTAGGGGTGTCAAAATTAATCGTTTCTGCTGTGCACCGCGATGCAGACGCGGACAATTCGGTATCGGTTCAGTAATAATCATAACCGGTTAGTATGTACTGACGCCATTTATCTCATATGCTCACTACCGCAAGGGAGGTGAGCGCGGGTGTTTACAACACTCCAGCAGCCAACTCAGAAACTGTGCACAATTTCACTGCATGTGTGTTTTTTTCCCTGACACTTACAACAGAAGCCCCTATTTCTCTACGATTGAGGGAATGAAAGTGAACT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa35014

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000012789	Nonsense	380	560	7	10

Genomic Location (Zv9):

Chromosome 11 (position 6202634)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	6170817
GRCz11	11	6168072

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GAACCCGTTCACCTTCATTGCCGGGCTGCTGCAGGCTCTCATCACTGCTT[T/A]GGGCACTTCATCAAGGTACAAATTTATTAATATAATTTACAAATCCCAGA

Long Flanking Sequence:

GGGATATTTAGAGTTAAAACTACACATACACACTCTATAGGGGCATCAGAGACTTATTTACATCTTTAAAAAAGCGGTATAATAGAAATCATATCAATAGATATCAGCATAATAAATTTCAACCTTTAATGATTTTTATGACCACTCTTTATTAGGATTTGCAGATGTCAGAAACAGATTTCCATACATTTGCTATTGATTGAAGTAGAAAAAAAATCATGAATAATTTAACTTCGAAACATATCAAATTTATTACTGTAAAATGCTGTGTCTGTTGCGCAGGTACGCTCCAGTGGGAATCCTCTTCCTGATAGCGGGGAAGATAGTGGAGATGAAGGATCTGGCTCAGGTTGGAGGACAGTTAGGGATGTACACGGTGTCTGTGATTGTGGGGCTGCTCATCCACGGCCTGTTGGTTCTGCCTCTGCTCTTCTTCGTGGTGACCAAGAAGAACCCGTTCACCTTCATTGCCGGGCTGCTGCAGGCTCTCATCACTGCTT[T/A]GGGCACTTCATCAAGGTACAAATTTATTAATATAATTTACAAATCCCAGAGAAACAATACAGAGCAATCTGATGTTGTAAATTGCTTGAGCACTGTTGCAGATGATCCATCTATTTGATAGACAGGTTTTTTATTTTGTTTCCAGGTATTAAGTATTTCCCAGGTTATGGTTTATAGACCAAGATTTTCACAGAATTTCCCATAATTTTTTTTCCTCTGGGGAAAGTCTCATTTTTTGTTAGTTTGGTGAGATCAGAGGTGCCCAAACTTTTTTGTATGAAGGGCAAAACAAAATATCCGAAGATAAATATACCAAACTATATTAAATTAAAGTTGTCGTGGGTAATTTATTTAATAACCCTACTGAAAAAGAACAGGTTAAACCAGTCTAGGTTGGTTTAAGCTGGATTTTTCAGCAGATATTTAAAAATAAATAATGGGCAATGCGGTGGTGCAGTGGGTAGTGCTGTCACCTCACAGCAAGAAGGTCACTGATTCGA

Associated Phenotype:

Not determined