Busch Lab

ZMP

cbl

Ensembl ID:
ENSDARG00000009958
ZFIN ID:
ZDB-GENE-041114-207
Description:
E3 ubiquitin-protein ligase CBL [Source:RefSeq peptide;Acc:NP_001007331]
Human Orthologue:
CBL
Human Description:
Cas-Br-M (murine) ecotropic retroviral transforming sequence [Source:HGNC Symbol;Acc:1541]
Mouse Orthologue:
Cbl
Mouse Description:
Casitas B-lineage lymphoma Gene [Source:MGI Symbol;Acc:MGI:88279]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa35879 Nonsense Mutation detected in F1 DNA Not yet available
sa42540 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa15300 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa35879
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006085 Nonsense 176 913 3 16
ENSDART00000130728 Nonsense 176 913 3 17
Genomic Location (Zv9):
Chromosome 15 (position 22597430)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23308617
GRCz11 15 23243882
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGGGGACAACTTCAGAATCACCAAAGCGGATGCCGCAGAGTTCTGGAGA[A/T]GATCGTTCGGGGACAAGTGAGATGCTTCATGTGCTCTTAGTACCCGTAAA
Long Flanking Sequence:
TTTTTTTTTTTTTTTAAGTTTTTTTTTTTTGTTGTTGAACACAAAAGAAGATGTTTTGAAAAATGTTGGAAAATTAGCTGTTTACTGACATCCAAAGCAGCAAAATTATACCATGGAAGGCAATATACATTCTAACATTCTTTTGTAAATTTATCATCTTTAGAGAAGTAAAATGCTAATAAAAATGCTCATAATTTAGAGAAAGTGGAGCACTAACAAATAATGACAGTGTTGTCATTTTTAGGTGAACTATACCTTTAGGGTAAAAAAAAAAGATCATCTGCTGGTGTAGACTCTAATAATGTTGTAATTATAGTTCTTAGTGTAAACAGACATTATTTTCCAAATATTCTCTTTTCTTGTCTTTCAGACGGAACTTAACAAAGTTGTCGCTGATTTTCAGTCACATGCTCGCTGAGCTCAAAGCCATCTTTCCTAATGGTCTGTTTCAAGGGGACAACTTCAGAATCACCAAAGCGGATGCCGCAGAGTTCTGGAGA[A/T]GATCGTTCGGGGACAAGTGAGATGCTTCATGTGCTCTTAGTACCCGTAAAAGATTAACATGTTCTATGAAAAAACAAAACAAAAGCAAGATGGACTTTGTCATGCTTTAGAAAACTGTTTCCAATAAGCTGAATTTCTCTGAATTTCAGGACCATTGTGCCTTGGAAGGTGTTCCGTCAGGCCCTGCATGAGTTTCACCCCATCAGCTCAGGCCTGGAGGCCATGGCACTGAAATCCACCATCGACCTCACATGCAACGACTACATCTCCGTTTTTGAGTTTGACATCTTCACCAGGCTATTCCAGGTGCGTCACTCAGTCACTCCATCACTTCCTCCAAGCACAGACTAGCTCCATTGTCTGTGCGCTTGCTCTGACAATGATTATTGTTGTGTGGCTGTGGCTACGGAGGCGCCGTTGAGTGCTGATGCTTCAGTTCTCATGGCTGAATGGAGGCCTCTTATCGCCTTTTGTTGCTCAAACAGGCTTGTCTGCACTCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42540
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006085 Essential Splice Site 511 913 10 16
ENSDART00000130728 Essential Splice Site 511 913 10 17
Genomic Location (Zv9):
Chromosome 15 (position 22609712)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23320899
GRCz11 15 23256164
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGGCCCACCAACCCTCCTGGGGCCTCAAGTCCAGGGGCCACATCCAAGG[T/C]AAATGCTCTAGCGGGGAATGTTTGGTCAAGTTTTCTTCACTTTTGGTACC
Long Flanking Sequence:
CATGTTTGGGGCTGAGGGAGCCCCTTCACCCAGCTACGACGATGATGATGATGACCGTTTAGAGGAAACTCCTTTCATGATTAGCAAGCTGGTCGGCTCTAAAGTGAGAATAACTTTCACCTTTTTGCTAAACCTGCAATAATGTGTCCGCTTCCTCGCCTCACCTCAGTGTCGCCTGCCTCAATAAATATTATTTTTAATTAGTTTGAGGCTGCCATTTTGAAGTTTAATATAGAAATTAACCCAAATCCAAACCAAACAACTCTTCCCGCATACACTTGACCAGGTTGCGGTAAAGGTTCTGAAATTCTGGCAGGAGTATTTAGCATCAGTGGAGCTGTGTGCTGAATGGTGTGACTTGTTTCAGGTGGAGAGGCCGCCCTCGCCGATGTCAATCTCCCCTCAGCCCGTCGTTCCTCCAGTACCTCCTCGGCTGGATCTGCTTCCTCTCAGGCCCACCAACCCTCCTGGGGCCTCAAGTCCAGGGGCCACATCCAAGG[T/C]AAATGCTCTAGCGGGGAATGTTTGGTCAAGTTTTCTTCACTTTTGGTACCTCAGGTTGAAACCCATTAAGCATTTTTTAATGCATCAGAAGGAAATGATGTTCAGATGCTACTGGAGTTTTTCCTAACTGGTTTTATCCCATTCCAGGCCCCTTCCCATCACAAAGACAAGCCATTACCGCTGCCGCCGGCTCTAAGGGATCTGCCACCTCCACCTCCCCCAGACCGTCCACACCCAGCTGGAGCAGACAACCGTCTCCCAAGACGTCCTCTCCCCAGTACGCCTGGAGACCCATCTCGTGACAAACTGCCCCCGGCCCCTCCTAACCGCAACATGCCAGACTGGAACTCCCGGCCTGTACCCAAAGCCCCATCACAGCCACCAGCAAGCGGAGACACCCGTGGATCTCGAGAGCTTTCCAACAGGCACTCTCTGCCTCTCCAACTGCCCTCTACTCTCGATTCCAGAACAGAAGCCCCCAGAAACAACGGCCCTCCCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15300
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006085 Nonsense 645 913 12 16
ENSDART00000130728 Nonsense 645 913 12 17
Genomic Location (Zv9):
Chromosome 15 (position 22610345)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23321532
GRCz11 15 23256797
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATGCTTTATGTGTGCAGAGTTTTGGATCATCRAATCCTGCATCGGATTA[T/G]GACAGTCCAAAAGTAAAGCCGTCTGCCTCGGCTAATGCCATCTATTCCTT
Long Flanking Sequence:
TTTATCCCATTCCAGGCCCCTTCCCATCACAAAGACAAGCCATTACCGCTGCCGCCGGCTCTAAGGGATCTGCCACCTCCACCTCCCCCAGACCGTCCACACCCAGCTGGAGCAGACAACCGTCTCCCAAGACGTCCTCTCCCCAGTACGCCTGGAGACCCATCTCGTGACAAACTGCCCCCGGCCCCTCCTAACCGCAACATGCCAGACTGGAACTCCCGGCCTGTACCCAAAGCCCCATCACAGCCACCAGCAAGCGGAGACACCCGTGGATCTCGAGAGCTTTCCAACAGGCACTCTCTGCCTCTCCAACTGCCCTCTACTCTCGATTCCAGAACAGAAGCCCCCAGAAACAACGGCCCTCCCAGCCTCGACCACCAGCTGGTAAGGACATGTGTGCCATAAGTACACCTTGACAGAAGCAGAAACTGAATATTTATTTAACTTTCACATGCTTTATGTGTGCAGAGTTTTGGATCATCGAATCCTGCATCGGATTA[T/G]GACAGTCCAAAAGTAAAGCCGTCTGCCTCGGCTAATGCCATCTATTCCTTGGCAATACGGTAAGTGCCACACAAAGTTGAAATAAAACTGTACAATAGGTGGGTGTGTGTGTCCACCAATTTTACCTCTGTAGGTGCTTGAATGTGCTTTGGAGGCAAAGTGTTTAAATAAACCCTTGGTGAGTTAAATGTTCCTCCAACTATTATCATTATGGTTTTTATATTTTTTTTTAGTTCAGAGAAGAAAGAATAGCAGAGTGCACACCACATCTACGAGGCTAATGGCACAAGGGAGCAGTGTTGCTTTTTTGCAGTTGATGAACAATAAAACATCCATCCTGATTTTAATAAAAGCTTACACATTTAAAGCAAAGTGAACTCCACTACATGCTTATTAATATATACAGATCATTATTTTGCATTAGTAATTAGGTTGTATTTAAAATGTTTTGTTCTCTGTGTGATCAGGGATGTTTTTATTTTTTTAGTATACCCAAGTTG
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3925
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000006085 Nonsense 863 913 16 16
ENSDART00000130728 Nonsense 863 913 16 17
Genomic Location (Zv9):
Chromosome 15 (position 22617811)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 23328998
GRCz11 15 23264263
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCGCAGACCCAGTCCAGTTCCCCCCGGGGCGAGTCCAGGCCCCAGCCAG[C/T]AGATCAGCAGTGAGATCGAGCACCTCTTGAGCCAGGGATACTCCCATCAG
Long Flanking Sequence:
TAAATTTGCTACGTGTGCTTTAAAGGAAAGCTCCAGTAGTTAGTATTTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTAGGCATAGACGTATCCTCACACACACAGAAAGAGACCAAATATAGGGCTGTATCATTTCCGCTTTCCACCTTTATTTATTTTAGATCACATCTCAACCCCATGAGAGTGTTATGGCTTTCACTGTGCTGCAATATGATCATTGTCTCAGACATCAGTGTACACACAGGCACTATTTTTATTCTGAATTGTATTTTCAGCTGTCCTGGACCCCTCTGAAGCCCCCGAGCGGCCTCCTAAGCCATTGCCCCGTCGCATCAACTCGGATCGCAGACCCAGTCCAGTTCCCCCCGGGGCGAGTCCAGGCCCCAGCCAG[C/T]AGATCAGCAGTGAGATCGAGCACCTCTTGAGCCAGGGATACTCCCATCAGGACATCCAAAAAGCCCTAATGATTGCACAGAACAATATTGAAATGGCCAAGAACATCCTGAGGGAGTTTGTGTCCATCCCTTCTACTGCACATATCTTAACATAACGAAACTTCTCAGTGCACCCAGTCGCAGCCCGGCCACGCTCGCCTCGTATTCGTCTTGGACTTCAGAAGTCAGTGGCGTGACCCTGCATTCTTGCTCTAGCGATGGCAAGAGCCTGTTTCTCCGTAACGCTTCTTGGATTCTCTGTCCTCCTTCGTGCGCAAGGAACAGCAAGGGTTTTTTTGCGGCCGCTTCTTCAGCCTGAAGCCAACGCATGTCCCTTGAGGCTAAACAAAGACAAAAAAAAAAGACAAAAACATGTATGTGTTTATATATGGTTTAATATATAAATCAGAATATTGAGTATAGTTAATATATACACATGTATGTTGGAGAGGCACAGGGTT
Associated Phenotype:
Not determined