Busch Lab

ZMP

ppp1r13b

Ensembl ID:
ENSDARG00000009142
ZFIN ID:
ZDB-GENE-030131-4327
Description:
apoptosis-stimulating of p53 protein 1 [Source:RefSeq peptide;Acc:NP_001038289]
Human Orthologue:
PPP1R13B
Human Description:
protein phosphatase 1, regulatory (inhibitor) subunit 13B [Source:HGNC Symbol;Acc:14950]
Mouse Orthologue:
Ppp1r13b
Mouse Description:
protein phosphatase 1, regulatory (inhibitor) subunit 13B Gene [Source:MGI Symbol;Acc:MGI:1336199]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa43417 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa37008 Nonsense Available for shipment Available now
sa39275 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa1183 Nonsense Confirmed mutation in F2 line Not yet available

Mutation Details

Allele Name:
sa43417
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047662 Essential Splice Site 53 1069 4 18
Genomic Location (Zv9):
Chromosome 20 (position 20838154)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 20866321
GRCz11 20 20765994
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAGATGTGATTTTTAAAGTGGTTTGTTGTTTTAATGTTCTCCCCTCTCC[A/T]GAGCGAGCCATTCCCTTTGACCACATGATGTATGAGCACCTGCAGAAATG
Long Flanking Sequence:
CCTTTAGCTAAAGCTTTGGCTCCAGGTTTCATGCAAGTTTAAATTGGCTGTTCTTACTTGCTTTGTAAATGTCCCTGAGCCCTAGAAGCTTTTCTTCACTTTCATACTTTCTTCTATTGTTCTGTGTGGTTTTATTCCATCCTCCTCTGGGTGTCCGCCAAACGTCCAGATGTCCCTTCACCTGTTATCAATGTCCAAAATATTGTTTTTACCCTTATCCATGTATCTGCTGCCCACCCAGCCTCACCACATTTCTCTGGCCGGATGCCACATTTGATTCAATTTCACTTTTCCATTGTTCCTTTGATCCCACTGTATTTGTTCTTCTGTTCTCCTCTCAGGTGTGCGTAACATTGGAATGAAACACACTTCAGGATAAGACAGTTTCTCTCCTGCTCTCTTTTTGATGTGAACACGCTTTGTTCCATTGAGAAATAAACACACTCTAAAAAAGATGTGATTTTTAAAGTGGTTTGTTGTTTTAATGTTCTCCCCTCTCC[A/T]GAGCGAGCCATTCCCTTTGACCACATGATGTATGAGCACCTGCAGAAATGGGGCCCTAGGAAGCAAGAGGTCAAGTTCTACCTACGCCATGAAGACTCGCCCACCGAAAGCAGCGATCAGGGTGAGAACACTCCCACTTTAATGGCTACAGGCCACATCACGCCCACCGCCGCCTTTATCTCATTGGCTGAGTAGCTGGATGTTTTTCATTCCCTCTCAGTGGCCTCTGACTTGTGAGAGAAAAAGACAAACACATTCTGGCCAAACAATGGAGGGTTCTGTTCATGATTCAGTTCTGTTGGGCTTTCACAAACTAAGAGATGTCAAAGTATCGTTGCAAGTGCAATGGCCTTCAAGCATCTATGAGCAAGGCACTAACTAAGAAATAATCTACCACAGCAAAATCAACTACTATGTATTTATACCATTCTATATAAAACCAACTACCATATATTTTCTTCAAAACTGATTCATGTACAATGTAATGTGTAATTATTGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37008
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047662 Nonsense 74 1069 4 18
Genomic Location (Zv9):
Chromosome 20 (position 20838218)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 20866385
GRCz11 20 20766058
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTTTGACCACATGATGTATGAGCACCTGCAGAAATGGGGCCCTAGGAAG[C/T]AAGAGGTCAAGTTCTACCTACGCCATGAAGACTCGCCCACCGAAAGCAGC
Long Flanking Sequence:
GTAAATGTCCCTGAGCCCTAGAAGCTTTTCTTCACTTTCATACTTTCTTCTATTGTTCTGTGTGGTTTTATTCCATCCTCCTCTGGGTGTCCGCCAAACGTCCAGATGTCCCTTCACCTGTTATCAATGTCCAAAATATTGTTTTTACCCTTATCCATGTATCTGCTGCCCACCCAGCCTCACCACATTTCTCTGGCCGGATGCCACATTTGATTCAATTTCACTTTTCCATTGTTCCTTTGATCCCACTGTATTTGTTCTTCTGTTCTCCTCTCAGGTGTGCGTAACATTGGAATGAAACACACTTCAGGATAAGACAGTTTCTCTCCTGCTCTCTTTTTGATGTGAACACGCTTTGTTCCATTGAGAAATAAACACACTCTAAAAAAGATGTGATTTTTAAAGTGGTTTGTTGTTTTAATGTTCTCCCCTCTCCAGAGCGAGCCATTCCCTTTGACCACATGATGTATGAGCACCTGCAGAAATGGGGCCCTAGGAAG[C/T]AAGAGGTCAAGTTCTACCTACGCCATGAAGACTCGCCCACCGAAAGCAGCGATCAGGGTGAGAACACTCCCACTTTAATGGCTACAGGCCACATCACGCCCACCGCCGCCTTTATCTCATTGGCTGAGTAGCTGGATGTTTTTCATTCCCTCTCAGTGGCCTCTGACTTGTGAGAGAAAAAGACAAACACATTCTGGCCAAACAATGGAGGGTTCTGTTCATGATTCAGTTCTGTTGGGCTTTCACAAACTAAGAGATGTCAAAGTATCGTTGCAAGTGCAATGGCCTTCAAGCATCTATGAGCAAGGCACTAACTAAGAAATAATCTACCACAGCAAAATCAACTACTATGTATTTATACCATTCTATATAAAACCAACTACCATATATTTTCTTCAAAACTGATTCATGTACAATGTAATGTGTAATTATTGGTTATGCAATGGAGCACCTTGCCTTTTTAAATCTTTACTGTTGTGGTGCAAAAAAACATTTAAAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39275
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047662 Essential Splice Site 116 1069 5 18
Genomic Location (Zv9):
Chromosome 20 (position 20841010)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 20869177
GRCz11 20 20768850
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCCAGCAGGAGAGGAGGAAGCAGCTCAGACACGCACAACGAGAACGGGG[T/C]TAGTTCATATCTCATCCTCATCAAAATGTGTGCCTTCTTTTCTAATCTTA
Long Flanking Sequence:
TCCTTTAAATGTGGGCAGGATTAGCTTGTAGCAAGCATCCACATAGATTAAGCCATAAACCTGAAACCCCCTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGGAGGGAGGGAGGGAGGGAGGGAGGGAAACAGAGGCAGTCATCCACTGAAAGCACAAGCTCCGTTCCCAGTGTCACATGGCAAAAACTAACAGCCCTTTAAACATTTGTCTTATGACGATGATGCGTTCTCCATTCAGCCAACCACCGTGTATTTTAAGATGCATTTTTGTTGTTCATTCATGATTATATGTATCAATTGAATGTGCTTTTTGTTTGATGCGCTCATTATGTTTTTAATTTCTTCACTCTCAGGGAGCCAGCAGTCTCAGGAGCAGCCCAGCAGGAGAGGAGGAAGCAGCTCAGACACGCACAACGAGAACGGGG[T/C]TAGTTCATATCTCATCCTCATCAAAATGTGTGCCTTCTTTTCTAATCTTAGCATTGTGGTTATTCCAAATGCATCCTAAGGGTTTTACTTCTCCTCCCGAAGAACATCTTGTGCTTTTCTGACCACTGTAATGCAAAGCAGCTGCCGCAAAAAGATTGAATCTGACACTTTTCAATACCGAAGCATTTCAGCCACATCGTGTCATTCAGGGTTTCTCTGTTAACCCTAGCCAAAAACAGCCAGAACCGTCACGTCCCAGAGTCACTCTGAATTTTCTTTCATATAAGCATTTGACACATCACTCATTCTTTTTGTGATCTGCTTCCTGCAAAAAGTTGTCATCTCGTCCAACCATCTGGCCCAGATTCCAACAGGGGAAAAGCCAGGCTCCAGAAAGCGGAACTAATTCCACCTTTAGGGAGAACGATGAGTGTAGACCACCAGTGTGTGTGAGTCGAGCAGCTCTTTCTTTTCGTATAGCTGTTCAGAGATGCAGTGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1183
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047662 Nonsense 648 1069 13 18
Genomic Location (Zv9):
Chromosome 20 (position 20877267)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 20905434
GRCz11 20 20805107
KASP Assay ID:
554-1093.1 (used for ordering genotyping assays)
KASP Sequence:
ACATGCTGGATTTTGAGCTGGACCTCGACGGTCAACTCATAGGCGTACCT[G/T]AACCACCTGCTCCCAGTGTGGACCACATCCCTCGACCCCTCAGCCCCACC
Long Flanking Sequence:
ATTCTTTTTCCAGCTGTAATTCAGTACTAGGAAACATCCATTCACTCTCATTCACTCACATACACCAGGGCCAATTTGGTTTATTCAATTCACCTATACCACATGTTTTTGGACTGTGGGGGAAACCAGAGCACCCGGAGGAAACCCACGCAAACACGCGGAGAACTTGCAAACTCCACACAGAAATGCCAACTGCCTCCGCTAGGACTCAAACCACTGACCTTCTTGCTGTGAGGCAACAGTGCTTACAACTGAGCCTCCGTGTCACTCAGTTCCAAGAACATGTTCTGTGTAATGTTTTTTTCTTGACTGTCTTTTAATTCCTGAGTATGTTGTTGTTCATCTCTGCAGTGTATGGTAAGCCACTCCTGCCTCCCAGTTCGACGCCCCCCTCTCCCTTACCTTATGGGAGTTCAGGAGCTTTCCCTGCCCTTCAGGGACCCGGAGGAGACATGCTGGATTTTGAGCTGGACCTCGACGGTCAACTCATAGGCGTACCT[G/T]AACCACCTGCTCCCAGTGTGGACCACATCCCTCGACCCCTCAGCCCCACCAAACTCACACCCATGGTCCACTCACCCATGCGCTACCAGAGCGATGCCGAACTGGAGGTGTTGCGCAAGAAATTAGCCAATGCTCCACGGCCTCTTAAGAAACGCAGCTCAATTACGGAACCAGAAGGTCCCAATGGACCCAACATCCAGAAGCTTCTCTATCAGCGCTTCAACACCCTGGCTGGAGGGATGGAGGGAGGGATTGGTGGAGTGAGCGGACCTGGTGGAGTGACTCCATTCTACCAGCCTTCTGTCTCCACTGCTGAAATGATTTTTGATGTTGACAATGGTAATCCACCTTCAGAAATTCCAGCTGTGCCATCAGAGGGCGCTGTTGCTGAGGAAGTGGTCCTGCAAGGTGATGCCAACGATAATGAGCCCCCAGAAGAAGAGGCTGAGAGCATAAGCCCTCCAGCGCCAGAGCCATCAGAAGACAGTAACAATAATCCT
Associated Phenotype:
Not determined