Busch Lab

ZMP

fgb

Ensembl ID:
ENSDARG00000008969
ZFIN ID:
ZDB-GENE-030131-9261
Description:
fibrinogen beta chain [Source:RefSeq peptide;Acc:NP_997939]
Human Orthologue:
FGB
Human Description:
fibrinogen beta chain [Source:HGNC Symbol;Acc:3662]
Mouse Orthologue:
Fgb
Mouse Description:
fibrinogen beta chain Gene [Source:MGI Symbol;Acc:MGI:99501]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa9621 Essential Splice Site Available for shipment Available now
sa298 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa9621
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000011701 Essential Splice Site 159 485 None 8
ENSDART00000041987 Essential Splice Site None 216 None 11

The following transcripts of ENSDARG00000008969 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 9130967)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 9370772
GRCz11 1 10054883
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATTCTMRACTATTAAAAATACCCACAAGTAATKGTTTATGTYCTTTCAC[A/C]GGCAATGGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCA
Long Flanking Sequence:
AAAGCCAACTGTAGAGCAGCTGAAAAGAGCTGTGGACGACTTGACTCAATCCACCAACTCCATCCACGGCTACGTCCTCGATATGACCGCAGAAGTAGCTCAAAGACAAAAAGTCAGCGAGGGTAACTACACTTCAGAAAGTTTTGTTTATATGATATTTGTTTTAAAGTAATAGTTGTCTAATGACTTGCCTAATTATGACTGATTACTATAGTATCTTTTCAAATATCTAGTAAAAAATTCTGTACTGACTGTCATCATGGCCGAGAAAAAAGAAATGAGTTATAGGAAATGAGTTATTAAAGCTATTATGTTTAAAAAGGACTTTTAAAAAGAATGAAAAGTTCACAGGAGGTCTAATAATTTCATTGCATGTCGAGTAAATTAATAAAAGTATAAGCATCCGCCTGACTAATACTGGTAGGCAACCTATTTTTTATATTTAATAGACATTCTCGACTATTAAAAATACCCACAAGTAATGGTTTATGTTCTTTCAC[A/C]GGCAATGGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCATGCTTATATTAAGGACACGGTGGACGTCACCTTCCCCCAGAACATTAAAGTCCTTCAGGGAGTGCTGGATAAGATCCGTGAGAAGATCCAGCGCTTGGAGAAAGCCATCACTACTCAGAGAGCCAAGTGCCAAGCGCCCTGTAAAGTCACCTGCCCCATTCCTGTTGTGTCCGGCAAGGAGTGCGAAGACATCATCCGCAAAGGAGGAGAGGACTCGCAGATGTACATCATACGGCCTGATCCGCTTGGAACGCCTTACAAGGTCTTCTGCGATCAGACCAGTAAAAATGGAGGTATGGCAACTTTGGCCTTGTCTACTCTATTACATTTTACAGTTACCCTAGACACAGCTTTTTCTGTAAACACACACAAAAAAAAAATCCATGTGGATATATTTGAAACTCACATAGAAATCTGATATATGCAAATTATTATGCAAAAACTGTTTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa298
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000011701 Nonsense 177 485 5 8
ENSDART00000041987 None None 216 5 11

The following transcripts of ENSDARG00000008969 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 9131024)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 9370829
GRCz11 1 10054940
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCATGCTTA[T/A]ATTAAGGACACGGTGGACGTCACCTTCCCCCAGAACATTAAAGTCCTTCA
Long Flanking Sequence:
CTCCATCCACGGCTACGTCCTCGATATGACCGCAGAAGTAGCTCAAAGACAAAAAGTCAGCGAGGGTAACTACACTTCAGAAAGTTTTGTTTATATGATATTTGTTTTAAAGTAATAGTTGTCTAATGACTTGCCTAATTATGACTGATTACTATAGTATCTTTTCAAATATCTAGTAAAAAATTCTGTACTGACTGTCATCATGGCCGAGAAAAAAGAAATGAGTTATAGGAAATGAGTTATTAAAGCTATTATGTTTAAAAAGGACTTTTAAAAAGAATGAAAAGTTCACAGGAGGTCTAATAATTTCATTGCATGTCGAGTAAATTAATAAAAGTATAAGCATCCGCCTGACTAATACTGGTAGGCAACCTATTTTTTATATTTAATAGACATTCTCGACTATTAAAAATACCCACAAGTAATGGTTTATGTTCTTTCACAGGCAATGGACTTGTGGTTGATCAGTACACAGACAGCTTAGAAACCCAGCATGCTTA[T/A]ATTAAGGACACGGTGGACGTCACCTTCCCCCAGAACATTAAAGTCCTTCAGGGAGTGCTGGATAAGATCCGTGAGAAGATCCAGCGCTTGGAGAAAGCCATCACTACTCAGAGAGCCAAGTGCCAAGCGCCCTGTAAAGTCACCTGCCCCATTCCTGTTGTGTCCGGCAAGGAGTGCGAAGACATCATCCGCAAAGGAGGAGAGGACTCGCAGATGTACATCATACGGCCTGATCCGCTTGGAACGCCTTACAAGGTCTTCTGCGATCAGACCAGTAAAAATGGAGGTATGGCAACTTTGGCCTTGTCTACTCTATTACATTTTACAGTTACCCTAGACACAGCTTTTTCTGTAAACACACACAAAAAAAAAATCCATGTGGATATATTTGAAACTCACATAGAAATCTGATATATGCAAATTATTATGCAAAAACTGTTTACTAATTACAAATATGTGCATATATGTTAAATTATATTAGCTATAATTTTATATATCGG
Associated Phenotype:
Not determined