Busch Lab

ZMP

mmp14b

Ensembl ID:
ENSDARG00000008388
ZFIN ID:
ZDB-GENE-030901-2
Description:
matrix metalloproteinase 14b (membrane-inserted) [Source:RefSeq peptide;Acc:NP_919395]
Human Orthologue:
MMP14
Human Description:
matrix metallopeptidase 14 (membrane-inserted) [Source:HGNC Symbol;Acc:7160]
Mouse Orthologue:
Mmp14
Mouse Description:
matrix metallopeptidase 14 (membrane-inserted) Gene [Source:MGI Symbol;Acc:MGI:101900]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa39891 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa2034 Nonsense F2 line generated Not yet available
sa5721 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa39891
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044264 Essential Splice Site 332 621 6 10
Genomic Location (Zv9):
Chromosome 2 (position 37880755)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 38195669
GRCz11 2 38177997
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCATTTTGACACCATTGGCATTTTCAGAGGAGAAATGTTTGTGTTTAAG[G/A]TACTGATGGAGTATGTGCTGCATTATTTTTGGAATAATGACTAGGAGATT
Long Flanking Sequence:
AAACGTTCAAGTTTGCGATGCAGTTTGCAAATTTTTATTGTATTGATGGATATGGGAAACACCAAATCAACGAACTATGTTTGTAATGACGCAACTTGCGACCTTAGTTGGCTAGCGATGGTTTTCAGAAACGCACCCCTGTATAGTAAAATCCAATAATAGAGCAGTATACCATTTCCAATTAATTTTCAGTTCAACTAGAGTGAAAAATAATAGTCAAGTACAGCATTTAATTACATATTAAGATGCTTTTGTCAATCAGTTATTTACACAGACCAATGCAAATAAGCTAATTCACTAAAATATTTATATATTTTGATTTAATCTCTGTAGGACCAGGATCTGGAGGACACCCTCGAACCCCTGTCACCCCTGAGACGCCCCATCACACTCCATACCCCACACCGTACAGGCCAGGAGGACCCTCCTATGGTCCCAACATCTGCGAGGGTCATTTTGACACCATTGGCATTTTCAGAGGAGAAATGTTTGTGTTTAAG[G/A]TACTGATGGAGTATGTGCTGCATTATTTTTGGAATAATGACTAGGAGATTGTTTGTTCATTATGGTTCCTGTCTCTGTGTTTTAGGGTAAGTGGTTCTGGCGTGTTCGAAATAATCAAGTTATGGAAAACTACCCCATGCCAATTGGACACTTCTGGAGAGGTCTGCCTACTGACATTAATGCTGCATATGAAAGAGAAGATGGCAAATTTGTCTTCTTTAAAGGTACTAGATCTATCTTATCGCATGAATTCAGTGGAGAATTTGCTTATTGACCCTGAAATACTACATTTGACATGTCTGGTTTGCAGGGGACAGGCATTGGGTGTTCACTGAGTCCAACTTAGAGCCAGGATACCCGAAGGTTTTAGGAGAACTGGGATCTGGTGTACCAAAGGACAAACTGGATGCAGCTCTTCTCTACACGCCTACAGGCTACACTTACTTCTTCAGAGGAAACAAGTCAGTAGCTTTGATGTCCCATAACATAAAGCACGAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2034
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044264 Nonsense 335 621 7 10
ENSDART00000044264 Nonsense 335 621 7 10
Genomic Location (Zv9):
Chromosome 2 (position 37880849)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 38195763
GRCz11 2 38178091
KASP Assay ID:
554-2622.1 (used for ordering genotyping assays)
KASP Sequence:
GGAGATTGTTTGTTCATTATGGTTCCTGTCTCTGTGTTTTAGGGTAAGTG[G/A]TTCTGGCGTGTTCGWAATAATCAAGTTATGGAAAACTACCCCATGCCAAT
Long Flanking Sequence:
CTTGCGACCTTAGTTGGCTAGCGATGGTTTTCAGAAACGCACCCCTGTATAGTAAAATCCAATAATAGAGCAGTATACCATTTCCAATTAATTTTCAGTTCAACTAGAGTGAAAAATAATAGTCAAGTACAGCATTTAATTACATATTAAGATGCTTTTGTCAATCAGTTATTTACACAGACCAATGCAAATAAGCTAATTCACTAAAATATTTATATATTTTGATTTAATCTCTGTAGGACCAGGATCTGGAGGACACCCTCGAACCCCTGTCACCCCTGAGACGCCCCATCACACTCCATACCCCACACCGTACAGGCCAGGAGGACCCTCCTATGGTCCCAACATCTGCGAGGGTCATTTTGACACCATTGGCATTTTCAGAGGAGAAATGTTTGTGTTTAAGGTACTGATGGAGTATGTGCTGCATTATTTTTGGAATAATGACTAGGAGATTGTTTGTTCATTATGGTTCCTGTCTCTGTGTTTTAGGGTAAGTG[G/A]TTCTGGCGTGTTCGAAATAATCAAGTTATGGAAAACTACCCCATGCCAATTGGACACTTCTGGAGAGGTCTGCCTACTGACATTAATGCTGCATATGAAAGAGAAGATGGCAAATTTGTCTTCTTTAAAGGTACTAGATCTATCTTATCGCATGAATTCAGTGGAGAATTTGCTTATTGACCCTGAAATACTACATTTGACATGTCTGGTTTGCAGGGGACAGGCATTGGGTGTTCACTGAGTCCAACTTAGAGCCAGGATACCCGAAGGTTTTAGGAGAACTGGGATCTGGTGTACCAAAGGACAAACTGGATGCAGCTCTTCTCTACACGCCTACAGGCTACACTTACTTCTTCAGAGGAAACAAGTCAGTAGCTTTGATGTCCCATAACATAAAGCACGAGCACAAAGAGAGCATAGATCTGAAACTGCTGCTTATCTTTCATCAGATATTATCGTTACAATGAAGACACGCACTCAGTGGATCCAGATTATCCCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5721
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000044264 Nonsense 335 621 7 10
ENSDART00000044264 Nonsense 335 621 7 10
Genomic Location (Zv9):
Chromosome 2 (position 37880849)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 38195763
GRCz11 2 38178091
KASP Assay ID:
554-2622.1 (used for ordering genotyping assays)
KASP Sequence:
GGAGATTGTTTGTTCATTATGGTTCCTGTCTCTGTGTTTTAGGGTAAGTG[G/A]TTCTGGCGTGTTCGWAATAATCAAGTTATGGAAAACTACCCCATGCCAAT
Long Flanking Sequence:
CTTGCGACCTTAGTTGGCTAGCGATGGTTTTCAGAAACGCACCCCTGTATAGTAAAATCCAATAATAGAGCAGTATACCATTTCCAATTAATTTTCAGTTCAACTAGAGTGAAAAATAATAGTCAAGTACAGCATTTAATTACATATTAAGATGCTTTTGTCAATCAGTTATTTACACAGACCAATGCAAATAAGCTAATTCACTAAAATATTTATATATTTTGATTTAATCTCTGTAGGACCAGGATCTGGAGGACACCCTCGAACCCCTGTCACCCCTGAGACGCCCCATCACACTCCATACCCCACACCGTACAGGCCAGGAGGACCCTCCTATGGTCCCAACATCTGCGAGGGTCATTTTGACACCATTGGCATTTTCAGAGGAGAAATGTTTGTGTTTAAGGTACTGATGGAGTATGTGCTGCATTATTTTTGGAATAATGACTAGGAGATTGTTTGTTCATTATGGTTCCTGTCTCTGTGTTTTAGGGTAAGTG[G/A]TTCTGGCGTGTTCGAAATAATCAAGTTATGGAAAACTACCCCATGCCAATTGGACACTTCTGGAGAGGTCTGCCTACTGACATTAATGCTGCATATGAAAGAGAAGATGGCAAATTTGTCTTCTTTAAAGGTACTAGATCTATCTTATCGCATGAATTCAGTGGAGAATTTGCTTATTGACCCTGAAATACTACATTTGACATGTCTGGTTTGCAGGGGACAGGCATTGGGTGTTCACTGAGTCCAACTTAGAGCCAGGATACCCGAAGGTTTTAGGAGAACTGGGATCTGGTGTACCAAAGGACAAACTGGATGCAGCTCTTCTCTACACGCCTACAGGCTACACTTACTTCTTCAGAGGAAACAAGTCAGTAGCTTTGATGTCCCATAACATAAAGCACGAGCACAAAGAGAGCATAGATCTGAAACTGCTGCTTATCTTTCATCAGATATTATCGTTACAATGAAGACACGCACTCAGTGGATCCAGATTATCCCAA
Associated Phenotype:
Not determined